D:Fibromyalgia

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Disease Term
Synonyms CHRONIC WIDESPREAD PAIN, Diffuse Myofascial Pain Syndrome, Fibromyalgia Fibromyositis Syndrome, Fibromyalgia Fibromyositis Syndromes, Fibromyalgia Primary, Fibromyalgia Secondary, FIBROMYALGIA SYNDROME, Fibromyalgias, Fibromyalgias Primary, Fibromyalgias Secondary, Fibromyositis Fibromyalgia Syndrome
Documents 1403
Hot Single Events 200
Hot Interactions 44

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Fibromyalgia. They are ordered first by their relevance to Fibromyalgia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 100.00
2 INT250975 Binding of FMOD and CSAD 1 0.01 0.86 0.41 100.00
3 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91 100.00
4 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59 100.00
5 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54 100.00
6 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 100.00
7 INT290376 Binding of CSF1R and MEFV 1 0.29 0.31 0.24 100.00
8 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22 100.00
9 INT260832 Binding of NRP2 and Nrp1 1 0.00 2.32 0.7 100.00
10 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07 100.00
11 INT260842 Binding of NRP2 and Kdr 1 0.00 2.28 0.85 100.00
12 INT254282 Sfpi1 Positive_regulation of Binding of Pam16 1 0.02 0.23 0.03 100.00
13 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03 100.00
14 INT177440 Binding of HPSE and Gnrh1 1 0.00 1.82 0.45 99.92
15 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 99.92
16 INT340274 Cd14 Regulation of Gene_expression of TNFRSF11A 1 0.05 0.8 0.05 99.90
17 INT165627 Binding of COMT and SLTM 1 0.09 0.86 0.88 99.76
18 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38 99.68
19 INT279286 Binding of TXK and VEGFA 3 0.05 2.35 0.07 98.48
20 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67 97.24
21 INT254285 Sfpi1 Positive_regulation of Gene_expression of THPO 1 0.02 0.17 0.03 96.28
22 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 95.52
23 INT158014 Binding of FLT1 and PGF 2 0.27 0.9 0.12 95.28
24 INT158013 Binding of FLT1 and VEGFC 1 0.23 0.34 0.07 95.28
25 INT84067 IGFBP1 Regulation of GH1 1 0.02 1.18 0.54 93.84
26 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65 93.84
27 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82 93.84
28 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 93.68
29 INT91393 Crh Positive_regulation of SST 1 0.01 0.73 0.58 93.04
30 INT177979 Binding of STAT3 and FOXI2 1 0.00 1.83 0.61 92.96
31 INT236723 VEGFA Positive_regulation of Positive_regulation of Ppara 1 0.12 1.01 0 92.40
32 INT292082 MIR1200 Negative_regulation of KDR 1 0.00 1.24 0 91.00
33 INT292091 MIR1200 Negative_regulation of PDGFRB 1 0.01 1.24 0 91.00
34 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57 90.32
35 INT158011 KLRF1 Positive_regulation of ENG 1 0.03 0.39 0.09 89.40
36 INT158012 Binding of ENG and FLT1 1 0.21 0.39 0.09 89.40
37 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28 87.36
38 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28 87.36
39 INT312303 Positive_regulation of FLT1 Positive_regulation of VEGFA 1 0.38 0.73 0.03 87.28
40 INT91391 Crh Regulation of Localization of Gnrh1 2 0.36 1.78 0.61 84.88
41 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 84.80
42 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64 84.16
43 INT177477 Crh Positive_regulation of Crh Regulation of POMC 1 0.02 0.86 0.22 84.16
44 INT92205 Crh Positive_regulation of Localization of SST 1 0.30 0.87 0.21 81.24
45 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21 79.92
46 INT340271 Fig4 Positive_regulation of Localization of RELA 1 0.01 0.68 0.04 79.52
47 INT183269 Binding of CEBPB and CPOX 1 0.07 1.61 0.89 77.44
48 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05 73.88
49 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 68.36
50 INT340214 BGLAP Regulation of Gene_expression of NFATC1 1 0.02 0.76 0 68.12
51 INT337157 Iqgap1 Regulation of Gene_expression of Ros1 1 0.07 1.91 0.72 67.48
52 INT290378 NOD2 Negative_regulation of TLR2 1 0.27 0.83 0.23 67.12
53 INT340276 Tnfsf11 Positive_regulation of Localization of RELA 1 0.02 0.58 0.03 66.44
54 INT304323 VEGFA Positive_regulation of Gene_expression of Ptger2 1 0.27 0.16 0.23 66.28
55 INT304324 VEGFA Positive_regulation of Gene_expression of Ptger4 1 0.27 0.16 0.23 66.28
56 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 65.60
57 INT290377 NOD2 Negative_regulation of Positive_regulation of TLR2 1 0.24 0.95 0.23 62.40
58 INT292081 Binding of EDN1 and NCOR2 1 0.00 0.98 0.03 58.40
59 INT221068 Cd79a Regulation of Gene_expression of IgG 1 0.01 0.93 0.1 55.36
60 INT221067 Cd79a Regulation of IgG 1 0.01 0.93 0.1 55.36
61 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1 55.16
62 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 53.12
63 INT292089 Binding of KIT and TXK 1 0.02 1.54 0.04 53.04
64 INT292090 Negative_regulation of Binding of KIT and TXK 1 0.02 1.54 0.04 53.04
65 INT292084 Binding of FLT3 and TXK 1 0.02 1.53 0.04 52.16
66 INT292085 Negative_regulation of Binding of FLT3 and TXK 1 0.02 1.54 0.04 52.16
67 INT292092 Binding of PDGFRB and TXK 1 0.05 1.53 0.04 51.60
68 INT292079 Negative_regulation of Binding of PDGFRB and TXK 1 0.06 1.54 0.04 51.60
69 INT292094 Binding of FLT4 and TXK 1 0.02 1.53 0.04 50.96
70 INT292093 Negative_regulation of Binding of FLT4 and TXK 1 0.03 1.53 0.04 50.96
71 INT292083 Binding of KDR and TXK 1 0.04 1.52 0.04 50.32
72 INT292095 Negative_regulation of Binding of KDR and TXK 1 0.04 1.53 0.04 50.32
73 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 50.00
74 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63 50.00
75 INT177480 Positive_regulation of Crh Positive_regulation of Regulation of POMC 1 0.06 0.46 0.14 50.00
76 INT241144 PGF Positive_regulation of FLT1 1 0.40 1.03 0.07 50.00
77 INT241143 VEGFA Positive_regulation of FLT1 1 0.20 0.51 0.04 50.00
78 INT292080 Binding of FLT1 and TXK 1 0.04 1.47 0.04 49.68
79 INT292086 Negative_regulation of Binding of FLT1 and TXK 1 0.04 1.48 0.04 49.68
80 INT244641 PDGFA Regulation of MTOR 1 0.07 2.55 0.06 48.96
81 INT320824 VEGFA Positive_regulation of DLL4 1 0.40 0.41 0 47.64
82 INT320825 VEGFA Positive_regulation of Gene_expression of DLL4 1 0.40 0.41 0 47.64
83 INT260837 NRP2 Negative_regulation of Negative_regulation of Bcl2 1 0.00 0.9 0.28 36.80
84 INT177980 CSF1R Regulation of PXN 1 0.07 0.48 0.11 32.84
85 INT281905 Binding of AGTR2 and NOS3 1 0.08 0.37 0.1 32.56
86 INT281899 Binding of ANG and NOS3 1 0.12 0.37 0.1 32.56
87 INT340273 Fig4 Regulation of BGLAP 1 0.00 0.55 0.04 30.56
88 INT254284 Binding of TNF and Tnfsf11 1 0.04 0.44 0.1 30.04
89 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 28.96
90 INT260840 NRP2 Positive_regulation of Gene_expression of Bcl2 1 0.00 0.85 0.24 28.72
91 INT340275 NFATC1 Positive_regulation of Binding of Ahr 1 0.10 0.51 0 26.88
92 INT260835 NRP2 Positive_regulation of Eif2ak3 1 0.00 0.73 0.23 25.20
93 INT260844 NRP2 Positive_regulation of Akt1 1 0.00 0.73 0.22 24.48
94 INT281912 Binding of AGTR2 and ANG 1 0.13 0.37 0.1 23.76
95 INT340272 Tnfsf11 Positive_regulation of Gene_expression of NFATC1 1 0.09 0.56 0 23.60
96 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13 10.16
97 INT281898 Binding of ANG and ACE Positive_regulation of KNG1 1 0.03 0.37 0.1 10.16
98 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
99 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
100 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
101 INT317584 Binding of Lbp and Pgp 1 0.24 1.08 0.99 5.00
102 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
103 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 5.00
104 INT317585 Binding of Lbp and Ppap2b 1 0.03 0.78 0.72 5.00
105 INT317586 Binding of SCLY and Ppap2b 1 0.00 0.78 0.72 5.00
106 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 5.00
107 INT181084 Binding of S100a8 and S100a9 6 0.42 2.91 0.62 5.00
108 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 5.00
109 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 5.00
110 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6 5.00
111 INT260821 NRP2 Positive_regulation of Gene_expression of TNF 1 0.01 1.48 0.56 5.00
112 INT260830 Binding of NRP2 and Flt1 Positive_regulation of Gene_expression of TNF 1 0.01 1.5 0.56 5.00
113 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56 5.00
114 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 5.00
115 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54 5.00
116 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54 5.00
117 INT177981 Binding of RUNX1 and SLC22A4 1 0.08 1.04 0.5 5.00
118 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48 5.00
119 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
120 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48 5.00
121 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47 5.00
122 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47 5.00
123 INT260839 Hivep3 Positive_regulation of Gene_expression of TNF 1 0.01 1.21 0.47 5.00
124 INT181080 Binding of Cx3cr1 and Darc 1 0.00 1.09 0.39 5.00
125 INT181081 Binding of Ccr1 and Darc 1 0.01 1.08 0.39 5.00
126 INT285560 Il23a Positive_regulation of Il17a 1 0.09 1.45 0.39 5.00
127 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39 5.00
128 INT285571 Binding of IL8 and Il17a 1 0.04 1.03 0.38 5.00
129 INT254278 Binding of Il13 and Il4 1 0.02 0.74 0.38 5.00
130 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 5.00
131 INT285557 Eae2 Positive_regulation of Cia1 1 0.02 1.85 0.36 5.00
132 INT285465 IL7 Positive_regulation of TNF 1 0.04 0.67 0.35 5.00
133 INT337156 Kdr Positive_regulation of Gtf3a 1 0.01 0.77 0.35 5.00
134 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34 5.00
135 INT285565 Positive_regulation of Zeb1 Negative_regulation of IL2 1 0.02 0.62 0.33 5.00
136 INT285558 Binding of Il11ra1 and Il27 1 0.05 1.1 0.33 5.00
137 INT285566 F8 Negative_regulation of IL2 1 0.00 0.62 0.33 5.00
138 INT304320 Binding of Ptger2 and Ptger4 2 0.26 0.06 0.33 5.00
139 INT285563 Zeb1 Negative_regulation of IL2 1 0.01 0.62 0.33 5.00
140 INT285567 Binding of IL1B and Cdc42 1 0.03 0.77 0.31 5.00
141 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31 5.00
142 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 5.00
143 INT260841 Il6 Positive_regulation of Localization of NRP2 1 0.00 0.7 0.29 5.00
144 INT260831 Pgf Positive_regulation of TNF 1 0.60 0.75 0.29 5.00
145 INT326438 Binding of HFE and TAPVR1 1 0.01 0.48 0.29 5.00
146 INT260828 Pgf Positive_regulation of Gene_expression of Gtf3a 1 0.01 0.73 0.28 5.00
147 INT337162 Binding of Kdr and Iqgap1 1 0.32 0.98 0.28 5.00
148 INT337161 Binding of Diap1 and Iqgap1 1 0.29 0.78 0.28 5.00
149 INT177978 Binding of CSF1R and SNRNP70 1 0.02 1.49 0.28 5.00
150 INT177977 RUNX1 Regulation of CSF1R 1 0.14 1 0.27 5.00
151 INT254283 Il10 Negative_regulation of Nfatc1 1 0.02 0.31 0.25 5.00
152 INT304321 Ptger4 Positive_regulation of Gene_expression of VEGFA 1 0.27 0.59 0.23 5.00
153 INT281896 KNG1 Regulation of Binding of KNG1 and NOS3 1 0.02 0.17 0.22 5.00
154 INT337158 Binding of Iqgap1 and Wasl 1 0.09 0.55 0.22 5.00
155 INT254281 Il4 Negative_regulation of Gene_expression of Acp5 1 0.02 0.41 0.22 5.00
156 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22 5.00
157 INT177982 Binding of RUNX1 and SNRNP70 1 0.01 0.89 0.21 5.00
158 INT281903 BDKRB1 Positive_regulation of KNG1 1 0.03 0.32 0.21 5.00
159 INT333053 IL6 Positive_regulation of Gene_expression of HNRNPA1 1 0.02 2.39 0.2 5.00
160 INT260827 Binding of Flt1 and Pgf 1 0.27 0.6 0.2 5.00
161 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19 5.00
162 INT181082 Binding of C3 and C3ar1 1 0.03 1.31 0.19 5.00
163 INT304325 Positive_regulation of Ptger2 Positive_regulation of Gene_expression of VEGFA 1 0.25 0.23 0.19 5.00
164 INT337154 Binding of Iqgap1 and Braf 1 0.13 0.64 0.18 5.00
165 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15 5.00
166 INT337164 Binding of DIAPH1 and Iqgap1 1 0.53 0.37 0.14 5.00
167 INT215010 Myoz1 Positive_regulation of Gene_expression of Il2 1 0.05 0.13 0.13 5.00
168 INT260834 Negative_regulation of Binding of VEGFA and Flt1 1 0.15 0.5 0.13 5.00
169 INT281911 Binding of ANG and MAS1 1 0.05 0.39 0.13 5.00
170 INT337155 Binding of Kdr and Ros1 1 0.06 0.46 0.12 5.00
171 INT337160 Binding of ecs and Ros1 1 0.01 0.46 0.12 5.00
172 INT337159 Binding of ecs and Kdr 1 0.04 0.46 0.12 5.00
173 INT181076 Map4k4 Positive_regulation of Mapk8 1 0.11 0.47 0.11 5.00
174 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11 5.00
175 INT337165 Iqgap1 Positive_regulation of Gene_expression of VEGFA 1 0.03 0.27 0.09 5.00
176 INT265346 Binding of Ocln and Tjp1 7 0.05 1.11 0.09 5.00
177 INT215007 Car2 Regulation of Gene_expression of Trpv6 1 0.07 0.25 0.09 5.00
178 INT342288 Binding of CD4 and HFE 1 0.01 1.26 0.08 5.00
179 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 5.00
180 INT244640 AGK Negative_regulation of KIT 1 0.00 0.69 0.08 5.00
181 INT244639 AGK Negative_regulation of PDGFRB 1 0.01 0.69 0.08 5.00
182 INT201543 Binding of NPC1 and RNASE1 1 0.07 1.33 0.08 5.00
183 INT254277 Binding of Hand1 and Tnfsf11 1 0.02 0.08 0.08 5.00
184 INT244638 AGK Negative_regulation of KDR 1 0.00 0.68 0.08 5.00
185 INT351651 Enpep Positive_regulation of Agt 1 0.22 0.93 0.07 5.00
186 INT351655 Avp Positive_regulation of Agt 1 0.11 0.94 0.07 5.00
187 INT281900 Positive_regulation of Binding of AGT and AGTR1 1 0.12 0.16 0.07 5.00
188 INT333051 Binding of HIVEP1 and NOLC1 1 0.00 4.11 0.07 5.00
189 INT265750 Binding of FLT1 and KDR 1 0.37 0.54 0.07 5.00
190 INT315987 Rhd Positive_regulation of Gene_expression of Igf1 1 0.10 0.47 0.07 5.00
191 INT215006 Myoz1 Regulation of Transcription of Il2 1 0.06 0.44 0.06 5.00
192 INT281909 Binding of AGT and AGTR1 1 0.09 0.16 0.06 5.00
193 INT258290 Hmgb1 Regulation of Positive_regulation of Tlr2 1 0.46 1.04 0.05 5.00
194 INT281906 BDKRB2 Positive_regulation of ANG 1 0.11 0.51 0.05 5.00
195 INT304322 Hif1a Positive_regulation of Positive_regulation of VEGFA 1 0.11 0.39 0.05 5.00
196 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05 5.00
197 INT201535 Binding of NPC1 and XRCC1 1 0.26 1.6 0.05 5.00
198 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05 5.00
199 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 5.00
200 INT236722 Ppara Positive_regulation of Binding of Apoa1 1 0.10 0.18 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Fibromyalgia. They are ordered first by their pain relevance and then by number of times they were reported in Fibromyalgia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT152433 Binding of CSF1R 6 0.33 10.97 5.54 100.00
2 INT262375 Binding of Fmod 1 0.20 12.37 10.1 100.00
3 INT250978 Binding of FMOD 4 0.16 12.32 8.75 100.00
4 INT250982 Positive_regulation of FMOD 7 0.24 8.65 6.09 100.00
5 INT177993 Localization of CSF1R 4 0.73 7.49 2.94 100.00
6 INT77855 Gene_expression of Pain1 55 0.75 67.42 54.1 100.00
7 INT250981 Gene_expression of FMOD 2 0.20 7.3 4.47 100.00
8 INT351278 Regulation of FMOD 1 0.09 6.45 5.16 100.00
9 INT178002 Positive_regulation of CSF1R 2 0.37 6.52 2.74 100.00
10 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 100.00
11 INT56985 Gene_expression of MEFV 56 0.71 46.71 9.47 100.00
12 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
13 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 100.00
14 INT152254 Gene_expression of CSF1R 16 0.75 12.93 3.81 100.00
15 INT351277 Positive_regulation of Gene_expression of FMOD 1 0.10 5.79 2.25 100.00
16 INT250983 Regulation of Gene_expression of FMOD 2 0.09 2.62 2.18 100.00
17 INT110394 Regulation of CSF1R 3 0.38 2.49 1.12 100.00
18 INT250980 Negative_regulation of FMOD 2 0.14 2.67 2.31 100.00
19 INT202162 Negative_regulation of Localization of ARSD 3 0.28 4.73 1.3 100.00
20 INT183147 Positive_regulation of Gene_expression of MEFV 6 0.50 4.67 1.73 100.00
21 INT59859 Localization of ARSD 11 0.65 9.67 1.88 100.00
22 INT129060 Gene_expression of Fmod 1 0.46 4.6 1.87 100.00
23 INT202161 Negative_regulation of CSF1R 3 0.31 3.36 1.22 100.00
24 INT321183 Regulation of Binding of Csrp1 1 0.11 2.64 0.98 100.00
25 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 100.00
26 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92 100.00
27 INT143125 Binding of FLT1 48 0.40 13.6 0.51 100.00
28 INT229561 Gene_expression of Flt3l 5 0.65 16.76 0.27 100.00
29 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27 100.00
30 INT202163 Negative_regulation of Localization of CSF1R 1 0.31 1.76 0.63 100.00
31 INT297931 Positive_regulation of Fmod 2 0.34 2.58 1.03 100.00
32 INT254614 Positive_regulation of Csf1r 1 0.26 1.31 0.65 100.00
33 INT153591 Binding of C7orf49 10 0.47 2.77 1.87 100.00
34 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09 100.00
35 INT290389 Positive_regulation of Binding of CSF1R 1 0.25 1.14 0.4 100.00
36 INT99163 Positive_regulation of Cd14 18 0.49 16.02 7.91 100.00
37 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91 100.00
38 INT109297 Negative_regulation of WSN 3 0.05 2.13 1.31 100.00
39 INT270304 Localization of FMOD 3 0.15 2.15 0.73 100.00
40 INT351279 Positive_regulation of Localization of FMOD 1 0.10 1.79 0.71 100.00
41 INT262373 Positive_regulation of Fmod 1 0.20 0.89 0.77 100.00
42 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45 100.00
43 INT42530 Gene_expression of Lct 11 0.66 9.37 1.37 100.00
44 INT290388 Regulation of Gene_expression of CSF1R 1 0.24 0.84 0.25 100.00
45 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 100.00
46 INT12835 Negative_regulation of Positive_regulation of CRH 6 0.42 3.15 1.76 100.00
47 INT98376 Gene_expression of tk 27 0.51 21.9 2.23 100.00
48 INT173100 Binding of KDR 39 0.39 22.48 0.81 100.00
49 INT90939 Positive_regulation of Eng 9 0.64 4.62 0.57 100.00
50 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 100.00
51 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31 100.00
52 INT254615 Binding of Csf1r 1 0.21 2.83 1.61 100.00
53 INT137702 Binding of TTN 7 0.35 4.48 3.62 100.00
54 INT194981 Regulation of IMPACT 5 0.38 1.47 0.63 100.00
55 INT153297 Regulation of MEFV 6 0.40 11.09 0.71 100.00
56 INT124124 Negative_regulation of Fmod 2 0.32 1.32 0.14 100.00
57 INT197103 Binding of FLT4 2 0.29 3.08 0.14 100.00
58 INT194342 Gene_expression of Csf1r 5 0.59 4.05 1.51 100.00
59 INT164087 Gene_expression of TPI1 42 0.78 5.39 3.21 100.00
60 INT117003 Binding of Sfpi1 5 0.47 5.04 1.74 100.00
61 INT255663 Binding of Flt1 11 0.32 6.92 1.64 100.00
62 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37 100.00
63 INT199567 Binding of Kdr 18 0.47 13.81 1.34 100.00
64 INT91368 Negative_regulation of Phosphorylation of STAT3 14 0.59 9.22 1.2 100.00
65 INT177994 Negative_regulation of Phosphorylation of CSF1R 1 0.39 1 0.34 100.00
66 INT177999 Phosphorylation of CSF1R 1 0.75 0.99 0.33 100.00
67 INT199555 Negative_regulation of Flt3 5 0.33 3.64 0.16 100.00
68 INT111546 Negative_regulation of Phosphorylation of FLT3 1 0.06 0.77 0.15 100.00
69 INT111538 Phosphorylation of Map3k3 2 0.61 0.85 0.15 100.00
70 INT111548 Phosphorylation of FLT3 1 0.12 0.77 0.15 100.00
71 INT111537 Negative_regulation of Phosphorylation of Map3k3 1 0.00 0.77 0.15 100.00
72 INT351647 Positive_regulation of Tie1 1 0.04 1.39 0.04 100.00
73 INT254267 Binding of Pam16 1 0.01 0.22 0 100.00
74 INT38204 Gene_expression of Acr 4 0.66 4.23 2.85 99.98
75 INT203183 Negative_regulation of C7orf49 4 0.05 3.23 2.9 99.98
76 INT13732 Negative_regulation of Regulation of GHRH 3 0.43 0.84 0.93 99.98
77 INT236703 Gene_expression of Tie1 1 0.03 1.06 0 99.98
78 INT68913 Gene_expression of Cd14 55 0.76 38.99 15.67 99.96
79 INT75923 Positive_regulation of IL6ST 5 0.45 2.49 1.21 99.96
80 INT1026 Binding of Lbp 207 0.48 150.96 119.16 99.92
81 INT177436 Binding of HPSE 2 0.47 1.81 0.52 99.92
82 INT14301 Binding of CSF2 82 0.48 67.95 8.98 99.92
83 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 99.92
84 INT2791 Regulation of Mb 53 0.61 23.03 10.73 99.92
85 INT114157 Positive_regulation of CTD 7 0.24 6.94 1.82 99.90
86 INT259821 Binding of CNTN3 1 0.01 1.22 0.74 99.88
87 INT88868 Binding of MCS 45 0.40 37.43 7.98 99.88
88 INT194289 Transcription of COMT 3 0.72 3.56 2.72 99.88
89 INT64184 Negative_regulation of Gene_expression of TNFRSF11A 7 0.57 2.81 0.22 99.86
90 INT53594 Binding of Csrp1 5 0.32 11.87 3.84 99.84
91 INT120828 Localization of CXCL10 29 0.68 18.01 12.17 99.84
92 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 99.84
93 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 99.84
94 INT81498 Positive_regulation of Gene_expression of CCL2 107 0.70 53.89 45.22 99.84
95 INT92237 Positive_regulation of Gene_expression of CXCL10 43 0.70 43.67 13.65 99.84
96 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.84
97 INT127667 Positive_regulation of Localization of CXCL10 5 0.59 5.89 4.09 99.84
98 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 99.84
99 INT177600 Gene_expression of C7orf49 21 0.52 7.1 6.92 99.84
100 INT203185 Negative_regulation of Gene_expression of C7orf49 1 0.03 1.33 1.09 99.84
101 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 99.84
102 INT276424 Negative_regulation of IMPACT 4 0.32 2.6 0.72 99.84
103 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93 99.82
104 INT94545 Positive_regulation of C7orf49 37 0.69 12.91 11.19 99.82
105 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 99.82
106 INT2336 Negative_regulation of Lct 51 0.58 33.79 13.73 99.82
107 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 99.80
108 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.80
109 INT81206 Binding of ENPEP 11 0.47 5.19 0.88 99.80
110 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.80
111 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11 99.80
112 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 99.80
113 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 99.78
114 INT78702 Positive_regulation of CCL11 13 0.68 12.94 2.74 99.78
115 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 99.78
116 INT333922 Negative_regulation of TDGF1 1 0.02 0.91 0.96 99.78
117 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 99.76
118 INT135629 Binding of COMT 33 0.48 16.68 19.37 99.76
119 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 99.76
120 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 99.76
121 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 99.76
122 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 99.76
123 INT177995 Phosphorylation of FOXI2 1 0.01 0.93 0.31 99.76
124 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 99.74
125 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 99.72
126 INT47909 Binding of CPP 32 0.48 24.9 13.79 99.72
127 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.68
128 INT1898 Regulation of Crh 220 0.62 61.33 102.64 99.68
129 INT21937 Positive_regulation of Scly 16 0.39 22.34 13.76 99.68
130 INT66416 Regulation of Pnoc 66 0.61 17.32 68.91 99.68
131 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 99.68
132 INT188449 Gene_expression of ENPEP 12 0.55 11.29 3.96 99.64
133 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 99.64
134 INT211363 Positive_regulation of RENBP 13 0.22 13.26 6.48 99.62
135 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 99.60
136 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 99.60
137 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 99.60
138 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 99.60
139 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 99.60
140 INT1562 Localization of Crh 499 0.81 126.74 236.68 99.58
141 INT77955 Negative_regulation of PCS 55 0.43 39.32 5.76 99.58
142 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 99.56
143 INT9655 Regulation of Il6 98 0.62 70.92 31.95 99.56
144 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32 99.56
145 INT259820 Negative_regulation of CNTN3 1 0.00 0.28 0.14 99.56
146 INT62511 Negative_regulation of MCS 20 0.50 6.77 2.35 99.56
147 INT58288 Positive_regulation of Gene_expression of Crp 83 0.61 82.23 23.7 99.52
148 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 99.48
149 INT254262 Gene_expression of Pam16 1 0.02 0.44 0.05 99.48
150 INT10228 Positive_regulation of PCS 49 0.67 28.72 7 99.44
151 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.40
152 INT38285 Positive_regulation of SCLY 8 0.36 3.32 3.96 99.40
153 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 99.40
154 INT111549 Phosphorylation of KITLG 2 0.37 1.13 0.15 99.40
155 INT111550 Negative_regulation of Phosphorylation of KITLG 1 0.02 0.75 0.15 99.40
156 INT921 Regulation of GH1 172 0.60 52.88 51.04 99.38
157 INT30153 Regulation of PTHLH 13 0.58 7.72 1.87 99.38
158 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 99.34
159 INT62945 Negative_regulation of Gene_expression of SELL 12 0.58 12.86 3.23 99.34
160 INT53683 Negative_regulation of Gene_expression of ITGB2 10 0.57 9.11 3.2 99.34
161 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 99.32
162 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34 99.32
163 INT105162 Gene_expression of Ad 47 0.12 46.53 1.83 99.32
164 INT199563 Negative_regulation of Abl1 38 0.46 21.5 0.87 99.32
165 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 99.32
166 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.30
167 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.28
168 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.28
169 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.28
170 INT44446 Regulation of Regulation of PLOD1 3 0.38 1.85 0.97 99.28
171 INT7975 Regulation of PLOD1 97 0.62 20.9 30.51 99.28
172 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 99.28
173 INT49371 Positive_regulation of Gene_expression of IGFBP3 27 0.70 23.13 1.9 99.28
174 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 99.28
175 INT5127 Localization of Lhb 488 0.80 50.48 162.66 99.28
176 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 99.28
177 INT139498 Gene_expression of SEMG1 13 0.67 3.67 1.98 99.24
178 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 99.24
179 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41 99.22
180 INT11937 Localization of Il6 228 0.81 139.83 64.39 99.20
181 INT4985 Positive_regulation of Tac1 81 0.69 35.79 50.67 99.20
182 INT122953 Gene_expression of COMT 65 0.77 25.84 40.49 99.16
183 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 99.16
184 INT113906 Regulation of Positive_regulation of CCL2 4 0.27 3.2 2.17 99.16
185 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71 99.14
186 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 99.14
187 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 99.14
188 INT139493 Gene_expression of Scly 11 0.57 16.96 7.61 99.14
189 INT252 Localization of GH1 529 0.80 227.4 122.05 99.12
190 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.12
191 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 99.12
192 INT140650 Positive_regulation of Gene_expression of CCL11 10 0.68 5.43 2.08 99.12
193 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 99.12
194 INT53491 Negative_regulation of Jun 28 0.57 14.2 6.9 99.12
195 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 99.12
196 INT7527 Gene_expression of SLTM 12 0.25 2.9 6.07 99.08
197 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94 99.08
198 INT167145 Regulation of Gene_expression of Ntf3 6 0.54 3.4 1.64 99.08
199 INT31572 Negative_regulation of FLT1 21 0.48 16.49 1.18 99.08
200 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 99.06
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