D:Fibrosis

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Disease Term
Synonyms Desmoplasia, Fibrogenesis, FIBROPLASIA, FIBROSES, Fibrotic, Fibrous Repair, Fibrous Replacement, Fibrous Thickening
Documents 4462
Hot Single Events 200
Hot Interactions 200

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Fibrosis. They are ordered first by their relevance to Fibrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52 100.00
2 INT131353 Binding of Npr1 and Nppb 1 0.27 1.73 0.4 100.00
3 INT131356 Binding of Nppa and Npr1 1 0.27 1.73 0.4 100.00
4 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19 100.00
5 INT303444 Timp1 Regulation of Fig4 1 0.15 0.43 0.39 100.00
6 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21 100.00
7 INT259634 Elane Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17 100.00
8 INT259633 Mmp9 Positive_regulation of Gene_expression of COPD 1 0.01 0.92 0.17 100.00
9 INT344429 Siglec5 Regulation of Gene_expression of Fn1 1 0.11 0.65 0.18 100.00
10 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43 100.00
11 INT164892 IL33 Regulation of Gene_expression of IL1RAP 1 0.06 0.2 0.18 100.00
12 INT323352 Binding of F8 and VWF 5 0.08 2.22 0.33 99.92
13 INT242992 Binding of Agt and Ppara 1 0.20 1.44 0.42 99.86
14 INT322207 CCL18 Regulation of Gene_expression of COL7A1 1 0.07 0.88 0.09 99.76
15 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25 99.72
16 INT281912 Binding of AGTR2 and ANG 1 0.13 0.37 0.1 99.66
17 INT281899 Binding of ANG and NOS3 1 0.12 0.37 0.1 99.66
18 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28 99.60
19 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27 99.60
20 INT343794 Binding of F8 and PTPRC 1 0.00 0.69 0.09 99.56
21 INT281905 Binding of AGTR2 and NOS3 1 0.08 0.37 0.1 99.52
22 INT322208 HRCT1 Positive_regulation of PDX1 1 0.01 1.31 0.34 99.44
23 INT192330 UBR7 Negative_regulation of Positive_regulation of PDGFRB 1 0.01 0.54 0.12 99.44
24 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25 99.28
25 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 99.24
26 INT111486 Binding of IFNG and IL8 1 0.13 0.28 0.15 99.14
27 INT239489 Spna1 Negative_regulation of Timp1 1 0.00 0.89 0.57 99.08
28 INT345157 Lpar1 Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.89 0.15 99.04
29 INT169604 Nppb Positive_regulation of Npr1 2 0.52 2.52 0.37 99.00
30 INT114903 POMC Regulation of Gene_expression of COL7A1 1 0.06 0.2 0.36 98.80
31 INT163418 Sub1 Positive_regulation of Pscs 1 0.07 0.23 0.12 98.76
32 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37 98.56
33 INT222974 NFKBIB Negative_regulation of NFKB2 Negative_regulation of ICAM1 1 0.00 1.6 0.33 98.52
34 INT222973 NFKBIB Negative_regulation of NFKB2 Negative_regulation of IL6 1 0.00 1.6 0.33 98.52
35 INT222976 NFKBIB Negative_regulation of NFKB2 1 0.01 1.58 0.32 98.52
36 INT202313 Gene_expression of PDGFB Positive_regulation of Positive_regulation of Pdgfrb 1 0.14 1 0.29 98.52
37 INT202314 Gene_expression of PDGFB Positive_regulation of Phosphorylation of Pdgfrb 1 0.14 1 0.29 98.52
38 INT299156 Smcp Negative_regulation of Tnc 1 0.05 0.7 0.22 98.40
39 INT164890 Binding of IL1RAP and IL33 1 0.09 0.2 0.36 98.24
40 INT205057 MMP3 Negative_regulation of MMP2 1 0.35 3.02 0.2 98.24
41 INT205051 MMP3 Negative_regulation of TIMP1 1 0.36 3.02 0.2 98.24
42 INT164894 Binding of IL1A and IL1RAP 1 0.08 0.1 0.18 98.24
43 INT164908 Binding of IL1RAP and IL1RL1 1 0.08 0.1 0.18 98.24
44 INT205055 MMP3 Negative_regulation of COL1A2 1 0.32 1.52 0.1 98.24
45 INT299155 Smcp Negative_regulation of Spp1 1 0.00 0.7 0.22 98.20
46 INT200637 Binding of Abpa and Ace 1 0.01 4.62 0.22 98.20
47 INT284705 CMA1 Positive_regulation of Gene_expression of COL7A1 1 0.04 0.49 0.05 98.16
48 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 98.04
49 INT169567 IL33 Regulation of Pscs 1 0.03 0.46 0.19 97.96
50 INT242991 Agt Positive_regulation of Gene_expression of Spp1 1 0.21 0.66 0.26 97.92
51 INT343825 IRF6 Regulation of Gene_expression of FUT1 1 0.00 1.74 0.5 97.88
52 INT299154 Smcp Negative_regulation of Lgals3 1 0.04 0.69 0.22 97.88
53 INT156681 REG3A Negative_regulation of Gene_expression of MMP1 1 0.05 0.39 0.19 97.84
54 INT192332 UBR7 Negative_regulation of TXK 1 0.00 1.38 0.63 97.78
55 INT192331 UBR7 Negative_regulation of INSRR 1 0.00 0.54 0.23 97.78
56 INT156448 ANGPTL5 Positive_regulation of Gene_expression of COL7A1 1 0.00 0.46 0.33 97.68
57 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 97.64
58 INT289769 Positive_regulation of Agtr2 Negative_regulation of Gene_expression of Col7a1 1 0.00 0.1 0.05 97.52
59 INT302422 IFNA1 Positive_regulation of Cxcl9 1 0.03 1.81 0.45 97.48
60 INT302421 IFNA1 Positive_regulation of Cxcl10 1 0.02 1.8 0.45 97.48
61 INT259635 Plau Positive_regulation of PLG 1 0.13 0.22 0.06 97.48
62 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14 97.40
63 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 97.24
64 INT257343 Lox Regulation of Cyba 1 0.02 0.37 0.05 97.20
65 INT349645 Eif2ak1 Positive_regulation of Hmox1 1 0.00 0.18 0.05 97.20
66 INT257338 Lox Regulation of Cybb 1 0.00 0.37 0.05 97.20
67 INT257339 Lox Regulation of Ncf1 1 0.02 0.37 0.05 97.20
68 INT325489 Agtr2 Positive_regulation of Ephx2 1 0.04 0.51 0.08 97.06
69 INT218706 Olr811 Positive_regulation of MMP1 1 0.00 3.16 0.45 96.96
70 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14 96.96
71 INT140183 Il4 Positive_regulation of Gene_expression of Il10 1 0.12 0.73 0.34 96.84
72 INT140181 Gene_expression of Il4 Positive_regulation of Gene_expression of Il10 1 0.17 0.73 0.34 96.84
73 INT316824 Negative_regulation of Sparc Negative_regulation of Gene_expression of Col7a1 1 0.10 0.82 0.09 96.68
74 INT202311 PDGFB Positive_regulation of Gene_expression of Fn1 1 0.02 0.7 0.16 96.68
75 INT349647 Eif2ak1 Positive_regulation of Positive_regulation of Hmox1 1 0.00 1.07 0.2 96.56
76 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13 96.48
77 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18 96.40
78 INT280008 Binding of IFNA1 and PAEP 2 0.08 1.29 0.25 96.40
79 INT147445 Pscs Positive_regulation of Gene_expression of CYBB 1 0.02 0.33 0.31 96.20
80 INT131355 Npr1 Regulation of Nppb 1 0.39 0.88 0.22 96.08
81 INT131354 Npr1 Regulation of Nppa 1 0.40 0.88 0.22 96.08
82 INT338418 Il13 Positive_regulation of Gene_expression of Il9 1 0.07 1.24 0.3 96.00
83 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57 95.84
84 INT183695 Binding of Tlr3 and Ducm1 1 0.04 2.75 0.56 95.60
85 INT183700 Binding of Pilra and Ducm1 1 0.00 2.35 0.53 95.60
86 INT202312 PDGFB Positive_regulation of Gene_expression of Col7a1 1 0.01 0.7 0.16 95.48
87 INT269313 Binding of Ptafr and Gp6 1 0.00 0.48 0.26 95.44
88 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33 95.44
89 INT164904 Binding of IL1A and IL33 1 0.39 0.19 0.35 95.36
90 INT302423 Etohi5 Positive_regulation of IFNA1 1 0.00 1.77 0.44 95.28
91 INT301665 CYP2C9 Regulation of Binding of Ppara 1 0.26 1.79 0.34 95.20
92 INT131357 Agtr2 Regulation of Ren 1 0.04 0.88 0.27 95.16
93 INT169468 Binding of Egfr and Spink3 1 0.37 3.73 1.83 95.08
94 INT169469 Binding of Egfr and Tgfa 1 0.19 1.87 0.91 95.08
95 INT164902 Binding of IL1RL1 and IL33 4 0.37 1.2 0.53 95.04
96 INT346455 IFNA1 Regulation of HCC 1 0.02 1.64 0.23 94.84
97 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 94.76
98 INT172145 IL10 Negative_regulation of Gene_expression of CSF2 1 0.04 0.69 0.59 94.76
99 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 94.68
100 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 94.60
101 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 94.60
102 INT316822 Sparc Regulation of Gene_expression of Ctgf 1 0.68 0.48 0.06 94.40
103 INT165855 Il13 Positive_regulation of Phosphorylation of Pscs 1 0.04 0.35 0.3 94.36
104 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 94.32
105 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 94.32
106 INT239488 Spna1 Negative_regulation of Gene_expression of Timp1 1 0.00 0.94 0.62 94.24
107 INT95730 Binding of CP and SPINK1 2 0.19 5.65 4.02 94.16
108 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11 94.08
109 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81 94.08
110 INT140095 Stat1 Positive_regulation of Positive_regulation of Ifng 1 0.52 0.42 0.18 94.04
111 INT325223 Il13 Regulation of Hrh4 1 0.38 0.58 0.11 94.00
112 INT325222 Il13 Regulation of Ahr 1 0.21 0.58 0.11 94.00
113 INT200635 Binding of Ace and Spink1 1 0.37 1.4 0.05 93.60
114 INT318387 Binding of Slc40a1 and Hrct1 1 0.02 0.88 0.08 93.48
115 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21 93.36
116 INT251349 Ifnar1 Positive_regulation of Rock1 1 0.01 1.27 0.16 93.28
117 INT68004 Binding of Hba-a1 and Vim 1 0.00 1.3 0.08 93.24
118 INT346459 Binding of RNASE1 and ROS1 1 0.06 1.42 0.18 93.12
119 INT316817 Ifnar1 Positive_regulation of Phosphorylation of Insrr 1 0.00 0.43 0.13 93.08
120 INT300304 Positive_regulation of Mapk14 Positive_regulation of Agt 1 0.14 1.5 0.08 92.96
121 INT68008 Binding of DES and Hba-a1 1 0.03 1.3 0.08 92.84
122 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89 92.80
123 INT316823 Sparc Positive_regulation of Phosphorylation of Smad2 1 0.44 0.49 0.1 92.52
124 INT321224 TLR4 Positive_regulation of NFKB1 1 0.04 1.02 0.25 92.48
125 INT114904 POMC Negative_regulation of Localization of FSD1L 1 0.02 0.09 0.2 92.32
126 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37 92.20
127 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37 92.20
128 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16 92.08
129 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 92.00
130 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2 91.76
131 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 91.76
132 INT199212 Binding of IGFBP1 and INS 1 0.05 1.77 0.04 91.76
133 INT321223 CXCR1 Positive_regulation of NFKB1 1 0.00 1.02 0.25 91.76
134 INT257342 Mapk4 Positive_regulation of Gene_expression of Ctgf 1 0.01 0.39 0.08 91.76
135 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71 91.72
136 INT316818 Sparc Regulation of Gene_expression of Col7a1 1 0.06 0.74 0.09 91.56
137 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2 91.44
138 INT146460 IFNG Positive_regulation of Gene_expression of TNFRSF10D 1 0.03 1.46 0.72 91.40
139 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12 91.28
140 INT332252 Stat6 Positive_regulation of Gene_expression of Il13 1 0.08 1.32 0.12 91.28
141 INT146462 TNFSF10 Positive_regulation of Gene_expression of TNFRSF10D 1 0.27 1.45 0.71 91.04
142 INT316815 Ctgf Negative_regulation of Gene_expression of Sparc 1 0.47 0.64 0.24 90.80
143 INT100783 Binding of CYP2B6 and CYP3A4 2 0.17 2 0.77 90.80
144 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44 90.72
145 INT102885 Binding of ANG and ACE 2 0.17 0.37 0.13 90.40
146 INT281898 Binding of ANG and ACE Positive_regulation of KNG1 1 0.03 0.37 0.1 90.40
147 INT274170 Il13 Regulation of Il4 3 0.09 2.75 0.51 90.20
148 INT294762 Il4 Regulation of Il13 2 0.09 0.92 0.32 90.20
149 INT344427 Il4 Regulation of Gene_expression of Siglec5 1 0.14 0.35 0.09 90.20
150 INT165853 Il13 Negative_regulation of Transcription of Nfkb1 1 0.37 0.33 0.3 90.08
151 INT165854 Il13 Negative_regulation of Nfkb1 1 0.37 0.33 0.3 90.08
152 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29 90.00
153 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29 90.00
154 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29 90.00
155 INT185809 Binding of PDX1 and SPP1 1 0.02 1.69 0.57 90.00
156 INT185806 Binding of PDX1 and MMP7 1 0.02 0.84 0.28 90.00
157 INT344433 Il13 Regulation of Gene_expression of Siglec5 1 0.18 0.35 0.09 89.84
158 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68 89.68
159 INT300308 Positive_regulation of Mapk14 Positive_regulation of Trib3 1 0.03 1.42 0.07 89.68
160 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 89.68
161 INT185813 Binding of MMP7 and Positive_regulation of SPP1 1 0.46 0.85 0.28 89.68
162 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 89.52
163 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 89.52
164 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43 89.36
165 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43 89.36
166 INT146463 TNFSF10 Positive_regulation of NFKB1 2 0.08 2.45 0.71 89.32
167 INT349648 Eif2ak1 Positive_regulation of Gene_expression of Hmox1 1 0.00 0.17 0.04 89.12
168 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4 89.04
169 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2 89.04
170 INT146461 IFNG Positive_regulation of NFKB1 1 0.01 1.44 0.71 89.04
171 INT107647 Ighg1 Negative_regulation of Arigg4 1 0.01 0.5 0.14 88.92
172 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84 88.92
173 INT300305 Mapk14 Positive_regulation of Gene_expression of Ctgf 1 0.19 1.25 0.17 88.92
174 INT335446 Binding of PDX1 and COPD 1 0.02 1.99 0.3 88.88
175 INT107645 Arigg4 Negative_regulation of Ighg1 1 0.01 0.5 0.14 88.56
176 INT332244 Il13 Positive_regulation of Gtf3a 1 0.01 1.21 0.15 88.56
177 INT250777 Binding of Cxcl10 and Cxcr1 1 0.14 3.1 1.04 88.40
178 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2 88.32
179 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4 87.96
180 INT274168 Egf Positive_regulation of Gene_expression of Muc5ac 1 0.01 2.11 0.17 87.76
181 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07 87.64
182 INT119583 Mpv17l Negative_regulation of Zmat3 1 0.00 0.4 0.45 87.60
183 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38 87.48
184 INT140094 Ifng Regulation of Gene_expression of Edn1 1 0.18 0.44 0.18 87.44
185 INT140093 Ifng Regulation of Gene_expression of Gtf3a 1 0.05 0.44 0.18 87.44
186 INT244328 ELF3 Negative_regulation of Positive_regulation of SH3GL3 3 0.20 1.26 0.04 87.44
187 INT230438 Binding of PDX1 and HAUS7 1 0.02 2.29 0.35 87.40
188 INT273171 PDE4A Regulation of IL8 1 0.05 0.53 0.15 87.24
189 INT192333 PDGFA Positive_regulation of Gene_expression of FN1 2 0.11 1.26 0.18 87.20
190 INT180928 Binding of Col7a1 and Mmp9 1 0.03 0.96 0.32 87.20
191 INT251348 Ifnar1 Positive_regulation of Limk2 1 0.01 1.12 0.11 87.20
192 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18 87.12
193 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 87.08
194 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3 87.04
195 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65 87.00
196 INT243466 POU1F1 Regulation of GH1 1 0.11 1.26 0.08 86.96
197 INT243464 POU1F1 Regulation of PRL 1 0.28 1.26 0.08 86.96
198 INT140096 Gtf3a Positive_regulation of Gene_expression of Edn1 1 0.02 0.44 0.18 86.48
199 INT157459 Binding of CX3CR1 and CX3CL1 1 0.32 2.12 1.7 86.36
200 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 86.08

Single Events

The table below shows the top 200 pain related interactions that have been reported for Fibrosis. They are ordered first by their pain relevance and then by number of times they were reported in Fibrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 100.00
2 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85 100.00
3 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06 100.00
4 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53 100.00
5 INT179788 Gene_expression of Sparc 42 0.77 19.96 2.57 100.00
6 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15 100.00
7 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 100.00
8 INT113604 Negative_regulation of Gene_expression of Ctgf 19 0.58 9.37 3.43 100.00
9 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 100.00
10 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 100.00
11 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
12 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 100.00
13 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 100.00
14 INT15723 Gene_expression of Fn1 47 0.78 37.59 8.51 100.00
15 INT70654 Gene_expression of Actg2 27 0.67 18.62 4.79 100.00
16 INT92681 Positive_regulation of Ctgf 13 0.69 9.78 3.47 100.00
17 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 100.00
18 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11 100.00
19 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 100.00
20 INT151123 Negative_regulation of Gene_expression of Csf2 21 0.53 21.76 3.22 100.00
21 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 100.00
22 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52 100.00
23 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32 100.00
24 INT15918 Gene_expression of Serpine1 60 0.62 41.73 7.72 100.00
25 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 100.00
26 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 100.00
27 INT264716 Negative_regulation of Gene_expression of Sparc 6 0.43 3.16 0.51 100.00
28 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36 100.00
29 INT296620 Negative_regulation of Gene_expression of Pin1 1 0.21 2.82 0.26 100.00
30 INT242989 Regulation of Gene_expression of Fn1 3 0.10 2.42 0.66 100.00
31 INT215202 Localization of Igfbp3 3 0.62 2.5 0.91 100.00
32 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 100.00
33 INT24671 Binding of FGF2 14 0.35 8.73 1.43 100.00
34 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6 100.00
35 INT94055 Gene_expression of Arg1 22 0.68 20.81 6.13 100.00
36 INT250771 Gene_expression of Atl1 3 0.43 2.45 0.75 100.00
37 INT170470 Binding of CD14 27 0.35 14.89 5.16 100.00
38 INT287003 Negative_regulation of Positive_regulation of Hmox1 2 0.34 3.1 0.63 100.00
39 INT179337 Positive_regulation of Gene_expression of Ecm1 14 0.05 3.73 0.58 100.00
40 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 100.00
41 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16 100.00
42 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
43 INT335991 Positive_regulation of Localization of Igfbp3 1 0.42 1.57 0.61 100.00
44 INT78706 Positive_regulation of Ksr1 2 0.08 1 0.78 100.00
45 INT139664 Gene_expression of CCL18 83 0.76 37.05 21.95 100.00
46 INT119248 Binding of Ctgf 1 0.35 1.5 0.35 100.00
47 INT252211 Negative_regulation of Lgals3 6 0.43 4.82 0.48 100.00
48 INT69289 Negative_regulation of Cftr 44 0.57 13.28 6.97 100.00
49 INT254818 Positive_regulation of Positive_regulation of Ecm1 4 0.06 5.27 0.24 100.00
50 INT47540 Binding of Cp 20 0.41 15.54 7.01 100.00
51 INT9664 Binding of LBP 127 0.48 94.9 63.42 100.00
52 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51 100.00
53 INT45112 Positive_regulation of PRB1 20 0.60 6.49 2.85 100.00
54 INT45111 Gene_expression of PRB1 15 0.58 4.16 0.47 100.00
55 INT65928 Positive_regulation of Gene_expression of Rac1 12 0.42 3.34 2.33 100.00
56 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 100.00
57 INT236349 Positive_regulation of Positive_regulation of Il17a 7 0.46 5.96 1.67 100.00
58 INT99610 Localization of MMP9 126 0.79 48.46 32.67 100.00
59 INT100400 Localization of CCL17 3 0.61 3.42 3.46 100.00
60 INT295676 Localization of CCL8 3 0.49 6.05 2.11 100.00
61 INT252714 Negative_regulation of Gene_expression of NAFLD2 1 0.03 3.74 0.23 100.00
62 INT200786 Positive_regulation of Gene_expression of Jak2 9 0.69 6.03 0.35 100.00
63 INT14690 Localization of CSF2 124 0.80 85.17 27.26 100.00
64 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 100.00
65 INT166146 Gene_expression of Ccr9 10 0.64 3.29 0.49 100.00
66 INT260922 Gene_expression of Alox15 2 0.32 0.58 0.27 100.00
67 INT217988 Gene_expression of Ear11 1 0.56 0.81 0.26 100.00
68 INT284065 Gene_expression of Reg3g 2 0.53 1.02 0.17 100.00
69 INT214391 Gene_expression of Cd5l 5 0.65 0.6 0.13 100.00
70 INT167376 Regulation of Aecp 2 0.16 1.65 0.59 100.00
71 INT153463 Localization of Ctgf 1 0.65 0.97 0.13 100.00
72 INT78901 Localization of CCL5 67 0.78 40.79 20.59 100.00
73 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 100.00
74 INT93886 Positive_regulation of Gene_expression of PGR 19 0.52 15.78 1.89 100.00
75 INT181422 Localization of CCL15 2 0.22 1.76 1.62 100.00
76 INT35788 Phosphorylation of Gpx3 5 0.06 0.66 1.52 100.00
77 INT24685 Localization of Serpine1 12 0.59 7.76 1.32 100.00
78 INT295685 Positive_regulation of Localization of CCL15 1 0.05 1.31 0.91 100.00
79 INT295692 Localization of CCL7 1 0.06 1.22 0.89 100.00
80 INT93885 Positive_regulation of Gene_expression of MKI67 8 0.60 4.4 0.18 100.00
81 INT96080 Regulation of UBE2D1 2 0.31 1.08 0.11 100.00
82 INT180032 Positive_regulation of CFM1 1 0.02 1.07 0.1 100.00
83 INT180033 Regulation of CFM1 2 0.21 1.09 0.1 100.00
84 INT129929 Transcription of LDHA 4 0.17 4.48 0.08 100.00
85 INT242742 Negative_regulation of Gene_expression of Nppa 2 0.34 1.29 0.05 100.00
86 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68 99.98
87 INT247021 Binding of GJA1 6 0.47 0.91 0.23 99.98
88 INT4141 Binding of Ptger1 19 0.31 2.96 4.83 99.98
89 INT28238 Positive_regulation of Hrct1 5 0.38 3.66 0.5 99.98
90 INT119753 Regulation of Pscs 7 0.45 12.88 4 99.96
91 INT81293 Positive_regulation of Gene_expression of Hmox1 53 0.70 41.54 7.25 99.96
92 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54 99.96
93 INT73432 Gene_expression of Nppa 32 0.59 21.04 1.39 99.96
94 INT37169 Positive_regulation of Binding of APCS 2 0.45 2.4 0.57 99.96
95 INT104250 Positive_regulation of Gene_expression of SPP1 17 0.69 13.22 1.44 99.96
96 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 99.96
97 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 99.96
98 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71 99.96
99 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.96
100 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75 99.96
101 INT155807 Positive_regulation of Gene_expression of Ccl4 8 0.40 5.13 1.9 99.96
102 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 99.96
103 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 99.92
104 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19 99.92
105 INT139317 Negative_regulation of Col1a2 8 0.41 7.17 1.54 99.92
106 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.92
107 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 99.92
108 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48 99.92
109 INT176517 Negative_regulation of Gene_expression of Spp1 18 0.59 15.31 2.28 99.92
110 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.92
111 INT9110 Binding of PAH 32 0.41 42.1 3.1 99.92
112 INT60065 Positive_regulation of Localization of NPEPPS 3 0.22 1.07 1.41 99.92
113 INT60067 Localization of NPEPPS 9 0.26 3.36 4.15 99.92
114 INT139514 Localization of EDNRB 7 0.73 4.63 1.52 99.92
115 INT90 Localization of Gast 400 0.81 137.67 113 99.92
116 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 99.92
117 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36 99.92
118 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 99.92
119 INT54571 Positive_regulation of NFKB1 263 0.70 138.99 87.32 99.92
120 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 99.92
121 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.92
122 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 99.92
123 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 99.92
124 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81 99.92
125 INT62832 Negative_regulation of Gene_expression of SELE 16 0.49 10.6 5.12 99.92
126 INT68576 Positive_regulation of Positive_regulation of CSF2 8 0.40 8.1 2.83 99.92
127 INT149158 Positive_regulation of Sema4g 1 0.00 1.2 0.31 99.92
128 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19 99.92
129 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.90
130 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 99.90
131 INT137614 Gene_expression of Lgals3 70 0.77 66.13 12.53 99.90
132 INT69768 Negative_regulation of Pscs 7 0.51 4.76 2.82 99.90
133 INT8989 Binding of Npr1 25 0.36 5.52 14.58 99.90
134 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 99.90
135 INT290420 Negative_regulation of Positive_regulation of Nppa 2 0.32 0.37 0.05 99.90
136 INT69769 Positive_regulation of Pscs 61 0.56 39.32 15.93 99.88
137 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 99.88
138 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.88
139 INT166707 Protein_catabolism of Col7a1 24 0.74 20.47 6.39 99.88
140 INT37170 Binding of APCS 6 0.36 4.79 0.97 99.88
141 INT321641 Negative_regulation of Binding of APCS 1 0.23 2.26 0.26 99.88
142 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 99.88
143 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 99.88
144 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 99.88
145 INT126030 Regulation of CFD 4 0.21 3.92 0.83 99.88
146 INT23955 Regulation of Vim 16 0.25 14.21 2.04 99.88
147 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 99.84
148 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 99.84
149 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 99.84
150 INT120509 Gene_expression of Cat 65 0.77 50.9 9.75 99.84
151 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 99.84
152 INT141542 Negative_regulation of Pin1 2 0.29 10.92 1.1 99.84
153 INT163666 Localization of Cat 8 0.80 5.84 1.57 99.84
154 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 99.84
155 INT213431 Positive_regulation of Gene_expression of MMRN1 15 0.24 9.91 1.96 99.84
156 INT20550 Gene_expression of Vwa2 8 0.04 4.29 2.14 99.84
157 INT111398 Localization of Mmp2 37 0.76 23.78 7.17 99.84
158 INT1285 Localization of Mmp13 12 0.78 8.98 4.93 99.84
159 INT113892 Binding of Cat 6 0.48 3.95 2.65 99.84
160 INT2681 Binding of Thra 11 0.32 5.98 1.27 99.84
161 INT111397 Localization of Timp1 17 0.70 11.67 8.76 99.84
162 INT107860 Positive_regulation of Gene_expression of F2RL1 10 0.68 6.36 3.88 99.84
163 INT245259 Localization of Mmp3 6 0.68 4.49 1.58 99.84
164 INT215914 Localization of Mmp14 4 0.59 2.26 1.98 99.84
165 INT317974 Localization of Timp2 1 0.38 0.88 0.3 99.84
166 INT173641 Regulation of MSC 13 0.39 2.85 1.82 99.84
167 INT173639 Positive_regulation of INCENP 40 0.14 20.97 6.7 99.84
168 INT120062 Binding of AIP 4 0.42 28.86 3.91 99.82
169 INT92684 Positive_regulation of Col3a1 5 0.56 1.79 0.45 99.82
170 INT157805 Negative_regulation of Gene_expression of Col7a1 22 0.34 12.85 3.51 99.80
171 INT22098 Positive_regulation of Il2 27 0.69 14.77 14.1 99.80
172 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75 99.80
173 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 99.80
174 INT1180 Gene_expression of Ren 63 0.77 27.33 10.51 99.78
175 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 99.78
176 INT81496 Gene_expression of CNR2 68 0.75 30.04 24.92 99.78
177 INT179791 Negative_regulation of Sparc 21 0.58 15.1 2.61 99.76
178 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 99.76
179 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4 99.76
180 INT3098 Positive_regulation of Epo 46 0.70 28.27 7 99.76
181 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 99.74
182 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 99.74
183 INT97310 Negative_regulation of Gene_expression of S100a8 2 0.29 1.83 1.07 99.74
184 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05 99.74
185 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97 99.74
186 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.72
187 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 99.72
188 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.72
189 INT266893 Negative_regulation of Gene_expression of Cat 4 0.58 3.76 0.55 99.72
190 INT343885 Negative_regulation of DNAJA1P5 2 0.41 2.51 0.64 99.72
191 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 99.70
192 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 99.70
193 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 99.70
194 INT287800 Positive_regulation of Positive_regulation of AIP 1 0.42 2.15 0.3 99.70
195 INT92686 Gene_expression of Ctgf 51 0.77 34.4 11.93 99.68
196 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.68
197 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.68
198 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 99.68
199 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.68
200 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 99.68
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