D:Filariasis

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Disease Term
Synonyms Elaeophoriases, Elaeophoriasis, Filariases, Filarioidea Infection, Filarioidea Infections, INFECTION FILARIOIDEA, Infections Filarioidea
Documents 102
Hot Single Events 24
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Filariasis. They are ordered first by their relevance to Filariasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT313687 Binding of BCR and IFIH1 1 0.09 0.23 0 56.88
2 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 50.00
3 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49 50.00
4 INT197096 VEGFA Positive_regulation of FLT4 1 0.04 1.43 0 33.64
5 INT197097 IL1B Regulation of FLT4 1 0.03 0.66 0.19 21.04
6 INT197098 TNF Regulation of FLT4 1 0.14 0.66 0.19 21.04
7 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19 18.80
8 INT197095 IL1B Regulation of Positive_regulation of TNF 1 0.01 0.64 0.19 16.64
9 INT197093 TNF Regulation of Positive_regulation of IL1B 1 0.01 0.64 0.19 16.64
10 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
11 INT351565 Binding of LPAR6 and SFXN5 1 0.00 1.1 0.17 5.00
12 INT275896 IFN1@ Positive_regulation of Gene_expression of TH1L 1 0.09 0.37 0.08 5.00
13 INT199041 AGRP Regulation of IGHE 1 0.00 1.39 0.03 5.00
14 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 5.00
15 INT197099 Negative_regulation of Binding of FLT4 and VEGFA 1 0.04 1.04 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Filariasis. They are ordered first by their pain relevance and then by number of times they were reported in Filariasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.96
2 INT178878 Regulation of Gene_expression of SRI 2 0.14 0.59 0.07 96.24
3 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 96.04
4 INT3127 Gene_expression of SRI 38 0.68 26.29 3.82 96.04
5 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 94.96
6 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 94.04
7 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 90.24
8 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 87.52
9 INT288383 Regulation of Gene_expression of CHIT1 1 0.18 2.99 0 87.08
10 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 86.64
11 INT241797 Gene_expression of CHIT1 10 0.24 9.75 0.69 86.20
12 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 85.84
13 INT188755 Positive_regulation of Binding of CSF2 6 0.44 8.79 0.35 84.40
14 INT197105 Negative_regulation of FLT4 13 0.42 11.48 0.92 83.36
15 INT192676 Binding of PTEN 14 0.46 10.58 3.06 82.52
16 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 82.48
17 INT288384 Binding of CHIT1 2 0.15 2.04 0.22 82.40
18 INT8775 Binding of IGHE 167 0.48 102.61 23.54 82.32
19 INT636 Binding of MRAP 54 0.48 40.36 18.77 82.32
20 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 82.04
21 INT197104 Positive_regulation of Gene_expression of FLT4 1 0.56 3.45 0.19 82.04
22 INT196007 Positive_regulation of FLT4 2 0.56 5.44 0.08 82.04
23 INT14301 Binding of CSF2 82 0.48 67.95 8.98 81.52
24 INT181790 Gene_expression of FLT4 13 0.72 11.73 0.56 81.24
25 INT10476 Binding of ALOX5 26 0.36 7.69 3.2 79.56
26 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 73.76
27 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 68.64
28 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52 67.84
29 INT22009 Negative_regulation of Ctsa 12 0.58 3.14 3.59 67.84
30 INT99524 Gene_expression of IFIH1 34 0.64 23.38 2.24 66.00
31 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 62.00
32 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 62.00
33 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10 61.08
34 INT22095 Negative_regulation of Dync1h1 11 0.48 5.17 1.08 57.04
35 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 51.12
36 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 50.00
37 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 50.00
38 INT183668 Binding of SGCA 15 0.36 9.86 2.42 50.00
39 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77 50.00
40 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44 50.00
41 INT188176 Positive_regulation of Gene_expression of CDH5 3 0.32 0.75 0.07 50.00
42 INT47625 Negative_regulation of IFIH1 4 0.51 1.68 0.39 49.88
43 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 42.32
44 INT115214 Gene_expression of LSAMP 4 0.63 2.5 1.14 40.24
45 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 36.20
46 INT196006 Regulation of FLT4 2 0.25 2.24 0.27 26.56
47 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 14.56
48 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 14.56
49 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
50 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
51 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
52 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
53 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
54 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
55 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
56 INT2893 Localization of Oxt 219 0.80 28.96 79.43 5.00
57 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 5.00
58 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
59 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 5.00
60 INT19775 Localization of Il1 183 0.78 145.5 50.91 5.00
61 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
62 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
63 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
64 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
65 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 5.00
66 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
67 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
68 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
69 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
70 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
71 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
72 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
73 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
74 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
75 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
76 INT73362 Negative_regulation of Abcb1a 46 0.59 8.78 17.81 5.00
77 INT24798 Negative_regulation of Glul 52 0.55 27.25 15.17 5.00
78 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 5.00
79 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
80 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76 5.00
81 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
82 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
83 INT32344 Localization of LTF 30 0.80 15.28 10.09 5.00
84 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 5.00
85 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 5.00
86 INT3622 Regulation of CTSB 34 0.58 16.08 8.76 5.00
87 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
88 INT177831 Gene_expression of HDAC1 24 0.65 21.37 8.37 5.00
89 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
90 INT91667 Localization of IL12A 39 0.74 25.51 7.36 5.00
91 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 5.00
92 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 5.00
93 INT17049 Localization of CD4 57 0.75 35.33 6.89 5.00
94 INT142949 Gene_expression of FPR2 27 0.71 26.17 5.58 5.00
95 INT59891 Positive_regulation of GSTK1 46 0.67 17.66 5.33 5.00
96 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
97 INT145 Negative_regulation of H1 12 0.39 5.68 5.08 5.00
98 INT11030 Binding of LPA 70 0.48 40.35 4.81 5.00
99 INT182898 Regulation of Gene_expression of IFN1@ 18 0.44 9.49 4.46 5.00
100 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 5.00
101 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
102 INT57645 Gene_expression of GSTK1 54 0.62 21.05 4.2 5.00
103 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01 5.00
104 INT129312 Gene_expression of SGCB 24 0.76 18.25 3.75 5.00
105 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
106 INT176386 Positive_regulation of Gene_expression of TH1L 14 0.32 9.17 3.4 5.00
107 INT76869 Localization of PAEP 15 0.73 6.57 3.36 5.00
108 INT184390 Binding of Arhgap4 13 0.36 3.29 3.35 5.00
109 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
110 INT110980 Gene_expression of CTSB 17 0.45 8.02 2.69 5.00
111 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 5.00
112 INT59135 Positive_regulation of CTSB 15 0.67 7.53 2.53 5.00
113 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 5.00
114 INT137972 Binding of P2RX7 12 0.36 8.01 2.18 5.00
115 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 5.00
116 INT36018 Negative_regulation of Gene_expression of CD8A 12 0.42 6.66 1.85 5.00
117 INT102843 Negative_regulation of PDC 5 0.57 4.26 1.82 5.00
118 INT64378 Gene_expression of DMRT1 9 0.54 1.72 1.71 5.00
119 INT89849 Regulation of Srgn 6 0.30 0.93 1.59 5.00
120 INT48775 Regulation of Gabbr2 3 0.41 0.15 1.55 5.00
121 INT192673 Gene_expression of Hdac5 6 0.61 2.84 1.51 5.00
122 INT23518 Gene_expression of Ctsa 6 0.32 1.11 1.16 5.00
123 INT192675 Positive_regulation of Gene_expression of Hdac5 2 0.33 2.52 1.13 5.00
124 INT60542 Positive_regulation of Gene_expression of GSTK1 11 0.39 6.21 1.13 5.00
125 INT91106 Negative_regulation of LTF 9 0.51 5.73 1.09 5.00
126 INT66725 Binding of Rars 6 0.48 8.7 1 5.00
127 INT147113 Binding of LTF 14 0.29 18.24 0.98 5.00
128 INT9100 Negative_regulation of CAMKK2 3 0.48 4.89 0.93 5.00
129 INT118217 Regulation of Cuzd1 2 0.30 2.36 0.91 5.00
130 INT81794 Regulation of AGRP 12 0.39 4.94 0.9 5.00
131 INT297919 Negative_regulation of Gene_expression of LTF 2 0.09 3.27 0.79 5.00
132 INT67389 Positive_regulation of SGCA 7 0.45 2.92 0.69 5.00
133 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 5.00
134 INT188775 Binding of IFIH1 11 0.16 12.4 0.61 5.00
135 INT188754 Localization of AGRP 15 0.74 8.88 0.6 5.00
136 INT182806 Binding of Cuzd1 3 0.24 1.45 0.53 5.00
137 INT182810 Gene_expression of Cuzd1 5 0.44 1.49 0.53 5.00
138 INT313688 Regulation of IFIH1 3 0.19 4.2 0.48 5.00
139 INT178589 Localization of IL2RA 3 0.68 1.99 0.45 5.00
140 INT95143 Negative_regulation of Rars 2 0.43 2.39 0.44 5.00
141 INT189176 Positive_regulation of Localization of TH1L 5 0.23 2.93 0.42 5.00
142 INT297921 Regulation of Gene_expression of LTF 2 0.10 3.11 0.37 5.00
143 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35 5.00
144 INT260330 Gene_expression of VPREB1 3 0.21 2.17 0.35 5.00
145 INT191731 Gene_expression of Lmrq1 31 0.43 14.46 0.34 5.00
146 INT152643 Positive_regulation of Gene_expression of IFIH1 5 0.42 5.2 0.28 5.00
147 INT201313 Gene_expression of MX1 27 0.75 16.63 0.28 5.00
148 INT157219 Gene_expression of WNK1 4 0.58 2.5 0.28 5.00
149 INT345678 Gene_expression of SCP2 1 0.11 0.74 0.27 5.00
150 INT275900 Regulation of Localization of TH1L 2 0.26 0.99 0.26 5.00
151 INT75648 Negative_regulation of CTD 4 0.07 3.91 0.25 5.00
152 INT214389 Gene_expression of 20S 5 0.65 0.88 0.22 5.00
153 INT351577 Negative_regulation of LPAR6 1 0.05 1.77 0.22 5.00
154 INT197102 Localization of FLT4 4 0.65 2.89 0.17 5.00
155 INT217052 Localization of Lmrq1 6 0.44 3.36 0.15 5.00
156 INT345683 Positive_regulation of SCP2 1 0.08 0.14 0.15 5.00
157 INT182807 Localization of Cuzd1 2 0.49 1.38 0.14 5.00
158 INT197103 Binding of FLT4 2 0.29 3.08 0.14 5.00
159 INT154235 Gene_expression of KPNA1 2 0.78 1.77 0.1 5.00
160 INT182809 Negative_regulation of Binding of Cuzd1 1 0.28 0.47 0.1 5.00
161 INT275899 Positive_regulation of Localization of Lmrq1 3 0.09 1.5 0.07 5.00
162 INT310717 Gene_expression of GFI1 2 0.11 2.44 0.06 5.00
163 INT351572 Gene_expression of SFXN5 1 0.04 1.26 0.06 5.00
164 INT197101 Positive_regulation of Localization of FLT4 1 0.38 0.77 0.06 5.00
165 INT351569 Negative_regulation of Localization of PAEP 1 0.11 1.2 0.06 5.00
166 INT351575 Negative_regulation of Positive_regulation of P2RX7 1 0.41 1.81 0.04 5.00
167 INT351570 Phosphorylation of CAMKK2 1 0.01 1.83 0.04 5.00
168 INT351571 Localization of SFXN5 1 0.05 0.67 0.04 5.00
169 INT351576 Negative_regulation of Phosphorylation of CAMKK2 1 0.01 1.84 0.04 5.00
170 INT345518 Gene_expression of Mtap1a 1 0.75 0.17 0.03 5.00
171 INT351573 Regulation of Localization of PAEP 1 0.12 1.25 0.03 5.00
172 INT345677 Negative_regulation of Gene_expression of DMRT1 1 0.04 0.17 0 5.00
173 INT267239 Binding of LSAMP 1 0.03 0.23 0 5.00
174 INT345679 Gene_expression of OBP2A 1 0.75 0.53 0 5.00
175 INT345675 Regulation of Gene_expression of GFI1 1 0.06 0.39 0 5.00
176 INT182808 Phosphorylation of Cuzd1 1 0.53 0.38 0 5.00
177 INT275898 Regulation of Localization of Lmrq1 1 0.07 0.48 0 5.00
178 INT189063 Regulation of NDS9 1 0.01 0.8 0 5.00
179 INT345673 Localization of CST2 1 0.00 0.07 0 5.00
180 INT345684 Transcription of DMRT1 1 0.05 0.17 0 5.00
181 INT345680 Localization of TMEM132D 1 0.68 0.48 0 5.00
182 INT202814 Binding of CEACAM5 1 0.17 1.14 0 5.00
183 INT189062 Negative_regulation of NDS9 1 0.01 0.93 0 5.00
184 INT281665 Binding of Ducm1 3 0.36 0.36 0 5.00
185 INT345668 Gene_expression of CST1 1 0.01 0.14 0 5.00
186 INT260240 Binding of HEPH 1 0.36 0.25 0 5.00
187 INT267241 Regulation of LSAMP 1 0.02 0.23 0 5.00
188 INT192674 Positive_regulation of Gene_expression of Dync1h1 1 0.32 1.67 0 5.00
189 INT345666 Positive_regulation of Gene_expression of GFI1 1 0.07 0.85 0 5.00
190 INT345669 Regulation of Gene_expression of WNK1 1 0.01 0.15 0 5.00
191 INT345681 Gene_expression of CST2 1 0.01 0.1 0 5.00
192 INT267240 Gene_expression of BST1 1 0.06 0.14 0 5.00
193 INT345671 Binding of GPR148 1 0.00 0.2 0 5.00
194 INT345670 Binding of OBP2A 1 0.47 0.23 0 5.00
195 INT345676 Binding of GFI1 1 0.06 0.69 0 5.00
196 INT345672 Negative_regulation of Binding of GFI1 1 0.05 0.35 0 5.00
197 INT260239 Localization of HEPH 1 0.78 0.48 0 5.00
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