D:Flushing

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Disease Term
Synonyms CUTANEOUS VASCULAR ENGORGEMENT, Face Goes Red, Flushing Reaction, FLUSHINGS, Reddening Of The Skin, Skin Flushed, SKIN REDDENING
Documents 39
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Flushing. They are ordered first by their relevance to Flushing and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT351001 Binding of Adh7 and Ins1 1 0.00 1.62 0.05 42.64
2 INT271889 Binding of DRD2 and ANKK1 1 0.23 0.36 0.55 17.32
3 INT271888 Binding of DRD2 and DNAJC7 1 0.14 0.36 0.55 17.32
4 INT271902 Binding of KCNK1 and Jun 1 0.12 0.08 0.53 5.00
5 INT186905 EIF1 Regulation of Gene_expression of IL8 1 0.07 0 0 5.00
6 INT186904 EIF1 Positive_regulation of Localization of IL8 1 0.06 0 0 5.00
7 INT186906 EIF1 Positive_regulation of Localization of LDHA 1 0.03 0 0 5.00
8 INT186902 EIF1 Positive_regulation of Gene_expression of IL8 1 0.08 0 0 5.00
9 INT208517 Binding of PAEP and PTPRC 1 0.02 0 0 5.00
10 INT186907 EIF1 Regulation of DEFB1 1 0.00 0 0 5.00
11 INT186910 DEFB1 Positive_regulation of Gene_expression of IL8 1 0.01 0 0 5.00
12 INT351002 Binding of Adh7 and Mrgpre 1 0.00 3.65 0 5.00
13 INT186909 IGKV2D-38 Positive_regulation of Localization of IL8 1 0.45 0 0 5.00
14 INT186908 EIF1 Positive_regulation of Transcription of IL8 1 0.06 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Flushing. They are ordered first by their pain relevance and then by number of times they were reported in Flushing. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT57360 Gene_expression of STAR 31 0.66 12.72 2.24 99.16
2 INT180497 Binding of MRI1 45 0.42 28.35 14.77 97.72
3 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35 96.72
4 INT89290 Regulation of MUC1 19 0.45 10.4 0.81 94.80
5 INT208524 Regulation of PTPRC 7 0.11 3.22 0.16 94.80
6 INT49802 Localization of MUC1 75 0.81 44.74 8.87 94.08
7 INT132163 Positive_regulation of Localization of MUC1 9 0.19 8.96 1.54 94.08
8 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 93.20
9 INT38266 Localization of PTPRC 30 0.68 17.05 1.68 92.80
10 INT350998 Positive_regulation of Adh7 1 0.01 1.25 0 92.48
11 INT163133 Gene_expression of ZBP1 28 0.65 18.59 1.25 92.24
12 INT8632 Regulation of Nfasc 15 0.54 2.87 9.08 73.36
13 INT1429 Gene_expression of PDYN 308 0.78 61.33 175.65 70.76
14 INT186912 Protein_catabolism of EIF1 1 0.10 1.88 0.39 65.72
15 INT186921 Protein_catabolism of DEFB1 9 0.23 1.85 0.35 65.72
16 INT125007 Gene_expression of DEFB1 30 0.60 4.14 1.32 65.24
17 INT186924 Gene_expression of EIF1 25 0.08 2.64 0.97 65.24
18 INT104168 Protein_catabolism of Nfasc 4 0.89 1.31 0.52 57.28
19 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 49.20
20 INT47839 Localization of Slc6a4 4 0.79 0.96 1.14 37.12
21 INT108997 Localization of Htt 28 0.77 3.76 1.07 36.20
22 INT447 Localization of Comt 4 0.75 0.76 1.8 35.96
23 INT1308 Localization of Pomc 457 0.81 66.83 217.5 34.32
24 INT28458 Localization of Slc6a3 31 0.76 2.33 12.49 33.76
25 INT86280 Positive_regulation of Nfasc 14 0.62 6.56 3.84 16.60
26 INT159423 Binding of ANKK1 4 0.47 0.9 1.35 16.52
27 INT271901 Binding of NRCAM 1 0.01 0.36 0.52 16.52
28 INT271898 Binding of DNAJC7 1 0.16 0.36 0.52 16.52
29 INT351000 Binding of Adh7 1 0.01 3.4 0.03 10.16
30 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31 10.08
31 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
32 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
33 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
34 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
35 INT1793 Localization of CGA 379 0.81 67.38 114.69 5.00
36 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
37 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
38 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 5.00
39 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
40 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
41 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
42 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
43 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
44 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
45 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49 5.00
46 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 5.00
47 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 5.00
48 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
49 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 5.00
50 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
51 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
52 INT4535 Localization of PROC 106 0.73 76.24 21.1 5.00
53 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54 5.00
54 INT5160 Localization of PTAFR 61 0.80 42.6 19.16 5.00
55 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
56 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
57 INT9246 Positive_regulation of Cat 113 0.70 52.73 18.04 5.00
58 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
59 INT52107 Transcription of IL8 63 0.72 41.66 16.06 5.00
60 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
61 INT20378 Localization of Hand1 53 0.71 41.96 13.31 5.00
62 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 5.00
63 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
64 INT9385 Localization of LDHA 74 0.81 31.67 10.5 5.00
65 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
66 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 5.00
67 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04 5.00
68 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03 5.00
69 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 5.00
70 INT72337 Positive_regulation of Positive_regulation of Nos2 37 0.65 17.02 8.11 5.00
71 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 5.00
72 INT10344 Localization of Jun 23 0.73 6.36 7.46 5.00
73 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25 5.00
74 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 5.00
75 INT800 Negative_regulation of Grhpr 21 0.42 10.3 7.17 5.00
76 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 5.00
77 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24 5.00
78 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99 5.00
79 INT1649 Localization of CSH1 15 0.46 3.65 5.75 5.00
80 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98 5.00
81 INT105923 Binding of FUT1 34 0.14 17.81 4.79 5.00
82 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 5.00
83 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 5.00
84 INT205272 Positive_regulation of Gene_expression of Plec 11 0.43 1.5 4.49 5.00
85 INT108579 Localization of Nfasc 18 0.72 3.47 4 5.00
86 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91 5.00
87 INT13302 Binding of PTAFR 20 0.48 7.03 3.7 5.00
88 INT10059 Binding of CSH1 17 0.35 5.28 3.37 5.00
89 INT76869 Localization of PAEP 15 0.73 6.57 3.36 5.00
90 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33 5.00
91 INT109095 Binding of Drd4 7 0.40 3.6 3.18 5.00
92 INT51680 Protein_catabolism of PTAFR 7 0.64 3.69 2.59 5.00
93 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51 5.00
94 INT12622 Localization of LGALS1 9 0.78 0.55 2.19 5.00
95 INT77651 Negative_regulation of Transcription of IL8 8 0.43 4.48 2.16 5.00
96 INT109971 Positive_regulation of Tpt1 23 0.69 13.69 2.14 5.00
97 INT171514 Binding of EP300 13 0.32 4.32 2.01 5.00
98 INT186920 Gene_expression of IGKV2D-38 30 0.44 17.17 1.9 5.00
99 INT205266 Regulation of Gene_expression of Plec 3 0.57 1.45 1.74 5.00
100 INT9380 Positive_regulation of Localization of LDHA 14 0.70 4.1 1.66 5.00
101 INT123223 Binding of TNFAIP6 5 0.35 3.36 1.65 5.00
102 INT53835 Negative_regulation of Localization of IL36RN 3 0.17 1.27 1.63 5.00
103 INT205269 Positive_regulation of Plec 8 0.43 1.78 1.55 5.00
104 INT147788 Regulation of FUT1 11 0.12 7.72 1.44 5.00
105 INT60571 Positive_regulation of Gsta4 8 0.45 3.76 1.44 5.00
106 INT186915 Binding of IGKV2D-38 15 0.23 7.14 1.32 5.00
107 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 5.00
108 INT119283 Binding of DRD1 3 0.33 0.95 1.23 5.00
109 INT123224 Gene_expression of TNFAIP6 12 0.70 7.13 1.21 5.00
110 INT181092 Negative_regulation of IGKV2D-38 9 0.27 4.31 1.09 5.00
111 INT138201 Transcription of PAEP 4 0.67 1.8 1.02 5.00
112 INT147464 Binding of Ptprc 13 0.36 15.18 0.98 5.00
113 INT8772 Positive_regulation of Gene_expression of HBG1 16 0.68 6.93 0.95 5.00
114 INT205275 Regulation of Plec 4 0.42 2.93 0.8 5.00
115 INT56406 Regulation of Gene_expression of PROC 4 0.05 1.52 0.79 5.00
116 INT124850 Gene_expression of Tpt1 42 0.77 14.51 0.79 5.00
117 INT70818 Negative_regulation of Adh7 2 0.16 1.04 0.79 5.00
118 INT205270 Regulation of Regulation of Plec 1 0.01 0.2 0.71 5.00
119 INT55885 Positive_regulation of EIF1 3 0.43 1.17 0.71 5.00
120 INT5262 Positive_regulation of AGL 14 0.40 7.51 0.65 5.00
121 INT208522 Gene_expression of SCGB1A1 7 0.65 3.2 0.58 5.00
122 INT271900 Localization of NR4A1 2 0.42 0.07 0.55 5.00
123 INT271899 Binding of KCNK1 1 0.11 0.08 0.53 5.00
124 INT189630 Gene_expression of PEX19 5 0.75 1.6 0.52 5.00
125 INT271897 Localization of JUNB 1 0.47 0.07 0.52 5.00
126 INT91210 Negative_regulation of Mrgpre 4 0.41 2.76 0.52 5.00
127 INT205268 Gene_expression of Rhd 6 0.65 0.67 0.51 5.00
128 INT186923 Positive_regulation of IGKV2D-38 12 0.31 2.69 0.46 5.00
129 INT2110 Localization of LIF 5 0.73 1.59 0.44 5.00
130 INT186914 Localization of DEFB1 4 0.78 1.27 0.44 5.00
131 INT205271 Binding of Synj2bp 1 0.01 0.29 0.42 5.00
132 INT51232 Positive_regulation of Localization of CSH1 3 0.31 0.32 0.37 5.00
133 INT205274 Gene_expression of Cs 2 0.75 2.08 0.36 5.00
134 INT319472 Phosphorylation of Abcd1 1 0.02 3.12 0.31 5.00
135 INT80059 Negative_regulation of Ptprc 8 0.41 1.85 0.25 5.00
136 INT196191 Binding of Mrgpre 7 0.14 5.84 0.25 5.00
137 INT317342 Positive_regulation of Localization of Nfasc 1 0.62 0 0.17 5.00
138 INT186911 Regulation of EIF1 1 0.03 0 0.16 5.00
139 INT186926 Localization of IGKV2D-38 3 0.47 0.86 0.16 5.00
140 INT186919 Regulation of IGKV2D-38 8 0.25 0.36 0.16 5.00
141 INT186917 Localization of EIF1 1 0.08 0.41 0.12 5.00
142 INT186918 Positive_regulation of Gene_expression of IGKV2D-38 4 0.28 3.92 0.11 5.00
143 INT124852 Positive_regulation of Gene_expression of Tpt1 10 0.50 3.95 0.1 5.00
144 INT205273 Gene_expression of Slc37a2 3 0.75 1.79 0.09 5.00
145 INT186916 Regulation of Gene_expression of IGKV2D-38 2 0.25 0.21 0.08 5.00
146 INT350999 Gene_expression of Adh7 1 0.02 1.64 0.05 5.00
147 INT186929 Positive_regulation of Gene_expression of EIF1 1 0.05 0.21 0 5.00
148 INT208521 Negative_regulation of Binding of SCGB1A1 1 0.18 0.16 0 5.00
149 INT186927 Transcription of EIF1 1 0.07 0 0 5.00
150 INT205335 Localization of UNG 2 0.73 1.99 0 5.00
151 INT186913 Positive_regulation of Gene_expression of DEFB1 1 0.01 0 0 5.00
152 INT208525 Positive_regulation of Gene_expression of SCGB1A1 1 0.19 0.11 0 5.00
153 INT319477 Negative_regulation of Gct1 1 0.05 0.14 0 5.00
154 INT208523 Binding of SCGB1A1 1 0.15 0.16 0 5.00
155 INT187639 Localization of TNFAIP6 1 0.11 0.72 0 5.00
156 INT186922 Negative_regulation of Gene_expression of IGKV2D-38 3 0.24 1.56 0 5.00
157 INT205334 Positive_regulation of Localization of UNG 1 0.49 0 0 5.00
158 INT186925 Positive_regulation of Negative_regulation of IGKV2D-38 1 0.28 0.21 0 5.00
159 INT208526 Negative_regulation of Gene_expression of SCGB1A1 1 0.18 0.25 0 5.00
160 INT186928 Binding of EIF1 1 0.04 0.22 0 5.00
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