D:Foreign-body Reaction

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Disease Term
Synonyms Foreign Body Reaction, REACTION FOREIGN BODY
Documents 143
Hot Single Events 3
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Foreign-body Reaction. They are ordered first by their relevance to Foreign-body Reaction and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18 60.32
2 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18 60.32
3 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0 27.40
4 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0 18.08
5 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0 18.08
6 INT323077 CPOX Negative_regulation of Gene_expression of Ptger2 1 0.00 1.57 1.05 5.00
7 INT257937 Binding of CSF2 and INVS 1 0.04 1.1 0.14 5.00
8 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0 5.00
9 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0 5.00
10 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0 5.00
11 INT337262 PRB1 Negative_regulation of THBS1 1 0.18 0.61 0 5.00
12 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0 5.00
13 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0 5.00
14 INT337257 GOPC Regulation of E2F1 Regulation of THBS1 1 0.06 0 0 5.00
15 INT337261 Binding of E2F1 and PRB1 1 0.17 1.19 0 5.00
16 INT337256 PRB1 Positive_regulation of E2F1 Positive_regulation of THBS1 1 0.22 0.61 0 5.00
17 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0 5.00
18 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0 5.00
19 INT337255 E2F1 Positive_regulation of E2F1 Positive_regulation of THBS1 1 0.47 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Foreign-body Reaction. They are ordered first by their pain relevance and then by number of times they were reported in Foreign-body Reaction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 90.68
2 INT76403 Gene_expression of Cnp 16 0.70 8.36 3.07 90.68
3 INT222650 Gene_expression of Col4a2 6 0.19 1.84 0.19 84.88
4 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 78.84
5 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45 76.12
6 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47 76.12
7 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 75.28
8 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 73.04
9 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 69.04
10 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 67.52
11 INT36689 Gene_expression of Bpifa2 27 0.50 14.92 1.65 58.96
12 INT205533 Localization of CS 4 0.28 0.69 0.06 58.60
13 INT53234 Regulation of Binding of Il1 7 0.35 5.92 1.25 56.32
14 INT15610 Localization of GOPC 223 0.65 68.26 28.7 55.80
15 INT25607 Binding of Il1 82 0.47 64.4 23.9 55.80
16 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18 52.96
17 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18 52.84
18 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 52.56
19 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 44.04
20 INT190208 Positive_regulation of MMRN1 15 0.23 14.1 3.37 42.24
21 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 41.08
22 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 31.80
23 INT201130 Localization of AES 31 0.63 25.45 5.12 31.80
24 INT23524 Positive_regulation of VCF 7 0.57 4.25 1.16 27.68
25 INT231474 Binding of THBS1 4 0.34 2.04 0.16 26.36
26 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 24.40
27 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 24.40
28 INT61645 Negative_regulation of Gc 15 0.51 10.44 2.71 23.88
29 INT61644 Gene_expression of Gc 16 0.70 11.35 1.95 23.88
30 INT111124 Positive_regulation of INVS 3 0.49 0.73 0.27 23.88
31 INT126993 Binding of E2F1 5 0.44 1.39 1.12 23.68
32 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 20.20
33 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 20.20
34 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3 16.80
35 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 9.28
36 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
37 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
38 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
39 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
40 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
41 INT3034 Localization of Ngf 126 0.81 50.81 72.84 5.00
42 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 5.00
43 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
44 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 5.00
45 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
46 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 5.00
47 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
48 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
49 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 5.00
50 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
51 INT17625 Localization of GCG 210 0.80 55.69 24.97 5.00
52 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 5.00
53 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 5.00
54 INT8518 Localization of Ifng 53 0.81 36.68 24.13 5.00
55 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 5.00
56 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 5.00
57 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 5.00
58 INT170444 Binding of Gopc 172 0.39 45.05 20.71 5.00
59 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 5.00
60 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 5.00
61 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 5.00
62 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
63 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 5.00
64 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
65 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
66 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
67 INT25396 Localization of Ptger2 83 0.78 46.81 14.81 5.00
68 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
69 INT25076 Negative_regulation of Gene_expression of Il1 41 0.52 30.58 13.85 5.00
70 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 5.00
71 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 5.00
72 INT4047 Binding of F13A1 105 0.43 66.54 11.81 5.00
73 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 5.00
74 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 5.00
75 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71 5.00
76 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 5.00
77 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 5.00
78 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
79 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
80 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 5.00
81 INT111397 Localization of Timp1 17 0.70 11.67 8.76 5.00
82 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 5.00
83 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 5.00
84 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 5.00
85 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 5.00
86 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 5.00
87 INT79168 Binding of TNC 39 0.47 16.51 7.55 5.00
88 INT60713 Binding of Col7a1 47 0.43 22.52 6.29 5.00
89 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27 5.00
90 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 5.00
91 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 5.00
92 INT134966 Localization of Col7a1 23 0.42 16.4 5.24 5.00
93 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 5.00
94 INT16214 Localization of F13A1 36 0.74 21.8 4.87 5.00
95 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73 5.00
96 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66 5.00
97 INT36133 Binding of pid 22 0.42 31.34 4.1 5.00
98 INT49700 Regulation of Localization of Ngf 6 0.59 1.18 3.95 5.00
99 INT157805 Negative_regulation of Gene_expression of Col7a1 22 0.34 12.85 3.51 5.00
100 INT22375 Localization of PDGFA 21 0.75 15.46 3.25 5.00
101 INT25393 Positive_regulation of Localization of Ptger2 19 0.32 9.69 3.23 5.00
102 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05 5.00
103 INT59454 Regulation of Gene_expression of CSF2 22 0.52 19.67 2.69 5.00
104 INT287307 Binding of ENO1 9 0.48 11.24 2.51 5.00
105 INT163283 Gene_expression of E2F1 21 0.71 3.77 2.26 5.00
106 INT1153 Negative_regulation of FUT3 17 0.38 8.61 2.21 5.00
107 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
108 INT173509 Positive_regulation of Localization of Timp1 5 0.41 2.99 2.04 5.00
109 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83 5.00
110 INT77415 Localization of GLP1R 23 0.63 11.1 1.69 5.00
111 INT11831 Positive_regulation of pid 13 0.40 23.37 1.54 5.00
112 INT287309 Positive_regulation of ENO1 5 0.59 5.67 1.52 5.00
113 INT94189 Positive_regulation of FUT3 11 0.31 6.61 1.5 5.00
114 INT74870 Gene_expression of Apo 17 0.75 12.5 1.38 5.00
115 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 5.00
116 INT306868 Positive_regulation of Gene_expression of E2F1 6 0.46 1.01 1.28 5.00
117 INT74254 Binding of PTPRC 16 0.36 8.37 1.27 5.00
118 INT170294 Regulation of Gene_expression of Mmp13 5 0.44 4.25 1.26 5.00
119 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26 5.00
120 INT18478 Protein_catabolism of CSF2 6 0.88 1.75 1.26 5.00
121 INT287308 Negative_regulation of ENO1 5 0.59 4.07 1.24 5.00
122 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23 5.00
123 INT19578 Negative_regulation of Gene_expression of F13A1 8 0.42 7.71 1.23 5.00
124 INT118368 Positive_regulation of E2F1 10 0.69 0.8 1.13 5.00
125 INT99767 Regulation of THBS1 18 0.42 11.51 1.03 5.00
126 INT38625 Gene_expression of ELL 8 0.58 12.53 1 5.00
127 INT125573 Gene_expression of CS 26 0.41 8 0.98 5.00
128 INT258932 Positive_regulation of TBX1 3 0.39 2.73 0.82 5.00
129 INT12115 Localization of VCF 3 0.70 2.67 0.8 5.00
130 INT126990 Positive_regulation of Binding of E2F1 4 0.58 0 0.79 5.00
131 INT144908 Gene_expression of SEA 15 0.52 3.81 0.79 5.00
132 INT57070 Protein_catabolism of VUR 19 0.99 18.75 0.76 5.00
133 INT108328 Negative_regulation of Gene_expression of CEL 6 0.57 2.56 0.63 5.00
134 INT306839 Negative_regulation of Gene_expression of E2F1 2 0.39 0.24 0.61 5.00
135 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59 5.00
136 INT179661 Gene_expression of Eln 9 0.56 7.59 0.58 5.00
137 INT228180 Regulation of Localization of Ptger2 2 0.06 3.58 0.54 5.00
138 INT91209 Binding of VIM 15 0.36 12.02 0.53 5.00
139 INT60712 Positive_regulation of Binding of Col7a1 2 0.43 0.53 0.52 5.00
140 INT118369 Regulation of E2F1 5 0.56 3.51 0.52 5.00
141 INT176646 Binding of Bpifa2 15 0.30 7.65 0.5 5.00
142 INT228298 Gene_expression of INVS 10 0.65 6.44 0.43 5.00
143 INT257938 Binding of HYDIN 1 0.01 3.74 0.39 5.00
144 INT147152 Negative_regulation of E2F1 6 0.56 0.89 0.38 5.00
145 INT36880 Negative_regulation of PRB1 9 0.37 1.37 0.38 5.00
146 INT257939 Transcription of CEBPZ 1 0.10 0.93 0.34 5.00
147 INT218795 Regulation of VCF 2 0.43 1.49 0.33 5.00
148 INT257940 Gene_expression of HYDIN 1 0.02 1.46 0.31 5.00
149 INT325303 Binding of DDC 3 0.30 1.04 0.28 5.00
150 INT188760 Regulation of ZC3H12A 4 0.04 4.02 0.27 5.00
151 INT179671 Binding of Eln 5 0.31 5.32 0.23 5.00
152 INT205532 Binding of CS 7 0.14 1.27 0.22 5.00
153 INT198393 Transcription of pid 2 0.51 2.01 0.2 5.00
154 INT210916 Regulation of Gene_expression of HAL 3 0.18 2.22 0.14 5.00
155 INT257942 Regulation of ETV1 1 0.01 1.26 0.11 5.00
156 INT353556 Negative_regulation of Transcription of CNP 1 0.37 0.45 0.09 5.00
157 INT353553 Transcription of CNP 1 0.60 0.45 0.09 5.00
158 INT353555 Binding of CNP 1 0.31 0.46 0.09 5.00
159 INT353554 Negative_regulation of CNP 1 0.37 0.4 0.08 5.00
160 INT257943 Regulation of Regulation of ZC3H12A 1 0.00 0.97 0.07 5.00
161 INT257941 Negative_regulation of ZC3H12A 1 0.01 0.59 0.05 5.00
162 INT341698 Localization of pid 1 0.06 0.88 0.05 5.00
163 INT294469 Transcription of THBS1 2 0.66 0.46 0.03 5.00
164 INT337281 Regulation of Gene_expression of THBS1 1 0.57 0.48 0 5.00
165 INT341697 Negative_regulation of Positive_regulation of pid 1 0.04 1.26 0 5.00
166 INT230768 Regulation of INVS 2 0.07 1.36 0 5.00
167 INT337279 Positive_regulation of Binding of THBS1 1 0.46 0 0 5.00
168 INT214025 Negative_regulation of INVS 4 0.07 3.36 0 5.00
169 INT270300 Positive_regulation of Localization of VCF 1 0.57 0.13 0 5.00
170 INT337283 Positive_regulation of Regulation of THBS1 1 0.46 0 0 5.00
171 INT307737 Binding of VCL 1 0.13 0.36 0 5.00
172 INT337280 Regulation of Gene_expression of E2F1 1 0.41 0.16 0 5.00
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