D:Foreign Bodies

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Disease Term
Synonyms Bodies Foreign, Body Foreign, Foreign Body
Documents 1438
Hot Single Events 96
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Foreign Bodies. They are ordered first by their relevance to Foreign Bodies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT305371 Binding of IL1RL1 and MRI1 1 0.09 0.95 0.15 90.72
2 INT148611 Binding of CD8A and Cr2 1 0.02 0.81 0.44 61.28
3 INT174901 Binding of GSPT2 and GTSE1 1 0.01 1.28 0.07 45.04
4 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33 5.00
5 INT274785 S100B Positive_regulation of Ngf 1 0.05 0.61 0.8 5.00
6 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
7 INT260551 Igh-Dex Negative_regulation of Il6 1 0.09 0.37 0.72 5.00
8 INT274786 Ngf Positive_regulation of Gene_expression of S100B 1 0.05 0.63 0.71 5.00
9 INT316690 Binding of Myd88 and Il1 2 0.06 1.75 0.66 5.00
10 INT316695 Binding of Il1 and gout 1 0.00 1.55 0.62 5.00
11 INT291018 Binding of NSF and USE1 1 0.03 0.98 0.46 5.00
12 INT316694 Binding of BLZF1 and Nlrp2 1 0.00 0.75 0.45 5.00
13 INT274781 Agrn Positive_regulation of Chrna2 1 0.08 0.18 0.41 5.00
14 INT316689 Gene_expression of Cd14 Negative_regulation of Gene_expression of Il1 1 0.09 1.31 0.35 5.00
15 INT316691 Negative_regulation of Cd14 Negative_regulation of Gene_expression of Il1 1 0.09 1.31 0.35 5.00
16 INT291019 Negative_regulation of Binding of NSF and USE1 1 0.03 0.59 0.26 5.00
17 INT299725 AFP Positive_regulation of Positive_regulation of ACPP 1 0.00 0.78 0.17 5.00
18 INT310263 Rb1 Negative_regulation of Gene_expression of Tnf 1 0.07 0.97 0.15 5.00
19 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
20 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
21 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
22 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
23 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
24 INT339897 Binding of Bnc1 and Shc4 1 0.05 0.69 0.07 5.00
25 INT203638 Binding of MR1 and GOPC 1 0.04 1.43 0.05 5.00
26 INT352392 Binding of ENOSF1 and Recql4 1 0.02 6.62 0 5.00
27 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
28 INT336469 Binding of CTS and SAFB 1 0.09 0 0 5.00
29 INT336468 Binding of CTS and ADAP1 1 0.02 0.42 0 5.00
30 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Foreign Bodies. They are ordered first by their pain relevance and then by number of times they were reported in Foreign Bodies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT70544 Negative_regulation of Fbrs 5 0.37 4.15 0.09 100.00
2 INT98739 Gene_expression of Fbrs 6 0.52 4.77 0.4 100.00
3 INT205957 Negative_regulation of Smo 4 0.08 2.57 0.6 100.00
4 INT252242 Gene_expression of Smo 1 0.01 0.23 0 100.00
5 INT173509 Positive_regulation of Localization of Timp1 5 0.41 2.99 2.04 99.70
6 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 99.64
7 INT81578 Gene_expression of TRAP 25 0.72 9.75 2.82 99.36
8 INT136085 Binding of NSF 2 0.35 3.02 0.75 99.24
9 INT24983 Binding of MPO 18 0.42 17.56 3.29 99.20
10 INT204563 Binding of Mpo 16 0.37 12.1 1.56 99.20
11 INT204258 Binding of NSMCE1 4 0.36 6.41 0.42 99.20
12 INT179671 Binding of Eln 5 0.31 5.32 0.23 99.08
13 INT102037 Localization of DYNLL1 2 0.78 0.32 0.08 98.76
14 INT102038 Negative_regulation of Localization of DYNLL1 1 0.42 0.24 0 98.76
15 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 98.36
16 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 98.36
17 INT229671 Transcription of D7Cwr3P 1 0.04 0.62 0.06 98.12
18 INT276437 Binding of Spir1 4 0.12 6.56 0 98.04
19 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 98.00
20 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 97.92
21 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 97.86
22 INT182809 Negative_regulation of Binding of Cuzd1 1 0.28 0.47 0.1 97.84
23 INT215107 Gene_expression of Spir1 17 0.50 10.38 0.25 97.66
24 INT89793 Positive_regulation of Igkv4-68 1 0.38 0.51 0.25 97.16
25 INT182806 Binding of Cuzd1 3 0.24 1.45 0.53 97.08
26 INT191589 Gene_expression of Msu 9 0.46 7.08 1.33 97.04
27 INT15299 Gene_expression of IL1RL1 37 0.69 10.09 3.43 96.96
28 INT111397 Localization of Timp1 17 0.70 11.67 8.76 96.94
29 INT208142 Gene_expression of PITX1 3 0.65 9.36 0.73 96.80
30 INT118217 Regulation of Cuzd1 2 0.30 2.36 0.91 96.12
31 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78 94.68
32 INT142425 Binding of Magmas-ps1 1 0.29 0.87 0.98 94.68
33 INT29693 Binding of Ahr 11 0.31 13.27 1.23 94.60
34 INT57277 Localization of ANGPTL5 5 0.19 2.15 0.84 94.08
35 INT155889 Binding of Nps 22 0.42 9.79 2.6 93.76
36 INT112386 Positive_regulation of Gene_expression of IL1RL1 4 0.47 2.72 0.77 93.60
37 INT71760 Binding of CSE 9 0.48 2.84 5.42 93.56
38 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 91.92
39 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 91.92
40 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 91.68
41 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 91.40
42 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 91.08
43 INT182810 Gene_expression of Cuzd1 5 0.44 1.49 0.53 91.04
44 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 90.80
45 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 90.52
46 INT10136 Negative_regulation of PLAT 23 0.42 11.18 3.02 89.72
47 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 89.56
48 INT23635 Positive_regulation of MMP12 31 0.59 28.19 17.95 89.56
49 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 89.56
50 INT190189 Positive_regulation of Localization of MMP12 4 0.58 2.87 3.18 89.56
51 INT193334 Gene_expression of HPYR1 11 0.53 10.36 0.88 89.32
52 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 89.20
53 INT180038 Gene_expression of D7Cwr3P 6 0.04 4.18 0.25 89.08
54 INT49379 Localization of MMP12 26 0.77 13.07 16.93 88.84
55 INT231952 Positive_regulation of Myh1 14 0.62 0.82 0.27 88.00
56 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 87.48
57 INT284 Positive_regulation of Ggt6 18 0.67 13.56 4.62 87.12
58 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 87.08
59 INT3808 Positive_regulation of Gif 3 0.41 2.51 0.75 86.84
60 INT345973 Binding of EVL 1 0.07 1.4 0.14 86.80
61 INT272272 Positive_regulation of Gene_expression of NARFL 17 0.40 18.85 0.31 86.68
62 INT320168 Regulation of APH1A 1 0.00 1.56 0.08 86.66
63 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 86.64
64 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 85.76
65 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 85.76
66 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 85.68
67 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 85.52
68 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 85.28
69 INT192761 Positive_regulation of Gene_expression of SAA1 5 0.40 7.45 0.82 85.28
70 INT320832 Negative_regulation of Tcp1 1 0.55 0.91 0.27 85.08
71 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 84.56
72 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35 84.56
73 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 84.24
74 INT10763 Localization of IL2 157 0.80 81.11 33.21 83.68
75 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 83.12
76 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 82.84
77 INT73330 Positive_regulation of SERPINB2 6 0.47 5.33 1.57 82.56
78 INT63309 Localization of GIF 2 0.78 1.14 0.06 82.40
79 INT61500 Binding of FN1 39 0.48 27.33 3.13 81.92
80 INT4809 Gene_expression of PTGDS 103 0.76 52.94 24.01 81.84
81 INT182807 Localization of Cuzd1 2 0.49 1.38 0.14 81.60
82 INT182808 Phosphorylation of Cuzd1 1 0.53 0.38 0 81.60
83 INT6852 Localization of TNF 883 0.81 705.95 270.84 81.52
84 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 81.52
85 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 81.52
86 INT193603 Localization of HTT 13 0.16 2.74 0.19 81.36
87 INT31341 Positive_regulation of CSE 15 0.60 11.57 12.29 81.16
88 INT38041 Gene_expression of epf 12 0.46 3.46 0.95 80.88
89 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45 80.76
90 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17 80.76
91 INT5320 Gene_expression of PTGFR 18 0.59 12.99 3.7 80.56
92 INT179661 Gene_expression of Eln 9 0.56 7.59 0.58 80.56
93 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 80.52
94 INT76403 Gene_expression of Cnp 16 0.70 8.36 3.07 80.52
95 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 80.16
96 INT245996 Binding of Gda 1 0.09 0.63 0.12 80.12
97 INT166010 Positive_regulation of Nsf 2 0.38 1.76 0.72 79.68
98 INT231950 Gene_expression of Myh1 31 0.69 3.7 0.51 78.96
99 INT231954 Positive_regulation of Gene_expression of Myh1 6 0.45 1.28 0.48 78.96
100 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 78.04
101 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 77.88
102 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 77.88
103 INT219610 Protein_catabolism of SAA1 2 0.90 4.47 0.54 77.64
104 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 76.48
105 INT291026 Gene_expression of NSF 1 0.53 4.05 0.91 76.44
106 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97 76.08
107 INT115108 Negative_regulation of Gene_expression of FAS 9 0.57 9.16 1.23 75.92
108 INT206798 Binding of VAMP7 1 0.30 2.23 0.26 75.64
109 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 75.44
110 INT9053 Negative_regulation of ALOX5 97 0.58 40.34 29.94 75.00
111 INT222650 Gene_expression of Col4a2 6 0.19 1.84 0.19 74.72
112 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 73.12
113 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 73.12
114 INT670 Gene_expression of B2m 31 0.66 27.32 8.49 72.88
115 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 72.76
116 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 72.76
117 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 70.28
118 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 70.16
119 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 70.16
120 INT193602 Negative_regulation of HTT 7 0.41 1.8 0 70.12
121 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 70.00
122 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 70.00
123 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 69.40
124 INT157805 Negative_regulation of Gene_expression of Col7a1 22 0.34 12.85 3.51 69.40
125 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 69.32
126 INT65642 Binding of Dync1h1 27 0.41 15.83 2.68 68.92
127 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 68.84
128 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 68.16
129 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 68.00
130 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 68.00
131 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47 67.52
132 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01 67.52
133 INT84881 Positive_regulation of Gene_expression of Pecam1 5 0.46 5.79 2.35 67.52
134 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 66.24
135 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84 66.24
136 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 66.24
137 INT100495 Localization of Gda 2 0.78 0.12 0.38 66.16
138 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78 64.08
139 INT264991 Positive_regulation of Localization of Tnfsf11 5 0.24 3.22 0.59 64.08
140 INT213689 Binding of HPYR1 4 0.29 4.69 0.41 63.28
141 INT19078 Binding of Ngf 78 0.48 31.03 44.33 62.48
142 INT22046 Negative_regulation of IRF6 52 0.43 25.69 14.13 62.28
143 INT125804 Localization of Pth 9 0.69 3.93 0.29 62.16
144 INT320983 Negative_regulation of Localization of Pth 2 0.38 1.17 0.09 62.16
145 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 61.60
146 INT45975 Positive_regulation of SAA1 17 0.67 19.7 4.15 61.36
147 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45 61.24
148 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 60.96
149 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 60.88
150 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 60.64
151 INT67144 Gene_expression of Cd44 17 0.76 8.94 4.48 60.48
152 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 60.20
153 INT65500 Gene_expression of App 605 0.78 429.94 98.31 60.00
154 INT98789 Negative_regulation of Gene_expression of App 54 0.58 40.27 11.15 60.00
155 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26 59.72
156 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 58.24
157 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 58.00
158 INT90852 Gene_expression of F2r 26 0.78 5.5 4.66 58.00
159 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 57.64
160 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 55.76
161 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 55.60
162 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 54.72
163 INT231947 Positive_regulation of Odam 1 0.06 0.34 0.41 54.24
164 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 53.96
165 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 53.96
166 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 53.84
167 INT245995 Protein_catabolism of Gda 1 0.21 0.05 0 52.64
168 INT38013 Gene_expression of Casr 30 0.73 6.03 3.09 52.40
169 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 52.08
170 INT321617 Negative_regulation of IMAGE 1 0.01 0.44 0.12 52.08
171 INT14166 Positive_regulation of Ahr 32 0.61 20.78 7.47 51.84
172 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 51.48
173 INT191669 Localization of Igh-Dex 8 0.26 4.35 3.54 51.36
174 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 50.32
175 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 50.00
176 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 50.00
177 INT88278 Binding of Kit 33 0.37 24.45 4.13 50.00
178 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 50.00
179 INT247971 Gene_expression of MAFD1 4 0.13 6.41 1.5 50.00
180 INT57256 Gene_expression of HLA-DQA2 52 0.55 23.87 6.27 48.64
181 INT257934 Negative_regulation of Gene_expression of HLA-DQA2 6 0.04 3 0.67 48.64
182 INT342591 Negative_regulation of Bp316 1 0.05 1.14 0.3 48.16
183 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 47.16
184 INT231946 Gene_expression of Odam 1 0.08 0.21 0.33 46.84
185 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 46.00
186 INT342590 Transcription of Bp316 1 0.06 0.55 0.23 45.96
187 INT254316 Binding of Msu 3 0.29 6.39 1.37 45.80
188 INT174157 Negative_regulation of Localization of Il12a 4 0.09 1.54 0.48 44.12
189 INT135722 Positive_regulation of Gene_expression of ANGPTL5 5 0.39 4.52 1.05 43.72
190 INT87239 Localization of Il12a 51 0.75 31.95 12.05 43.68
191 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 43.16
192 INT291025 Positive_regulation of NSF 1 0.34 1.5 0.56 43.12
193 INT189289 Negative_regulation of Gene_expression of H2 4 0.18 1.27 0.56 43.00
194 INT324671 Positive_regulation of DSPP 1 0.02 0.08 0 42.52
195 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 42.12
196 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 42.00
197 INT9020 Binding of Tsv 2 0.25 1.28 0.48 41.76
198 INT173974 Positive_regulation of Localization of Il10 25 0.68 16.81 5.87 41.08
199 INT90792 Localization of Il10 144 0.80 87.88 30.03 40.72
200 INT194848 Negative_regulation of Localization of Il10 11 0.36 8.29 3.38 40.72
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