D:Francisella Infection

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Deer Fly Fever, F TULARENSIS, Francisella Infections, Francisella Tularensis, Glandular Tularaemia, Glandular Tularemia, Oculoglandular Tularaemia, Oculoglandular Tularemia, Rabbit Fever, Tularaemia, Tularemia
Documents 56
Hot Single Events 75
Hot Interactions 9

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Francisella Infection. They are ordered first by their relevance to Francisella Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT297427 Flg Positive_regulation of Gene_expression of Il13 1 0.11 1.2 0.3 100.00
2 INT297428 Lvs Positive_regulation of Gene_expression of Il13 1 0.06 1.2 0.3 99.98
3 INT297422 Lvs Positive_regulation of Gene_expression of Il4 1 0.04 1.2 0.3 99.98
4 INT316537 Binding of Tlr1 and Il23a 1 0.12 0.78 0 94.80
5 INT316536 Binding of Tlr2 and Il23a 1 0.11 0.78 0 94.80
6 INT297424 Gene_expression of Stat6 Regulation of Ppara 1 0.17 1.19 0.38 89.56
7 INT297426 Stat6 Regulation of Ppara 1 0.17 1.19 0.38 89.56
8 INT297423 Gene_expression of Il4 Regulation of Ppara 1 0.07 1.19 0.38 89.32
9 INT297425 Il4 Regulation of Ppara 1 0.07 1.17 0.38 89.12
10 INT315945 IgG Positive_regulation of Gene_expression of Ighm 1 0.13 0.56 0.04 58.28
11 INT315943 Ighm Positive_regulation of Gene_expression of IgG 1 0.13 0.56 0.04 58.28
12 INT315942 Binding of Tlr4 and Lvs 1 0.08 0.78 0 53.76
13 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91 41.76
14 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86 5.00
15 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 5.00
16 INT260433 Dbi Positive_regulation of Cd8a 1 0.00 0.13 0.3 5.00
17 INT260438 Binding of Cd4 and Mx1 1 0.00 1.52 0.29 5.00
18 INT260434 Binding of Cd8a and Mx1 1 0.00 1.52 0.29 5.00
19 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26 5.00
20 INT260437 Positive_regulation of Tlr7 Positive_regulation of Positive_regulation of Il12a 1 0.03 0.27 0.21 5.00
21 INT260440 Negative_regulation of Tlr9 Negative_regulation of Positive_regulation of IFNA1 1 0.03 0.96 0.21 5.00
22 INT260441 Negative_regulation of Tlr7 Negative_regulation of Positive_regulation of IFNA1 1 0.05 0.96 0.21 5.00
23 INT316538 Lvs Positive_regulation of Gene_expression of Il17a 1 0.30 1.3 0.21 5.00
24 INT260436 Positive_regulation of Tlr9 Negative_regulation of Positive_regulation of Tlr7 1 0.14 0.65 0.2 5.00
25 INT284889 Gene_expression of Hand1 Positive_regulation of Gene_expression of Il4 1 0.21 0.4 0.18 5.00
26 INT316535 Il23a Regulation of Il12a 1 0.07 1.15 0.15 5.00
27 INT316539 Il17a Positive_regulation of Gene_expression of Lvs 1 0.22 1.02 0.08 5.00
28 INT260442 Binding of IFNA1 and Il6 1 0.01 1.07 0.07 5.00
29 INT260439 Positive_regulation of Binding of IFNA1 and Il6 1 0.01 1.08 0.07 5.00
30 INT260435 Binding of Tlr9 and Tlr7 1 0.09 0.71 0.05 5.00
31 INT315941 Binding of Tlr4 and Mthfd1 1 0.05 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Francisella Infection. They are ordered first by their pain relevance and then by number of times they were reported in Francisella Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT116727 Gene_expression of Flg 3 0.53 3.13 0.34 100.00
2 INT163253 Binding of Flg 3 0.31 3.6 0.32 100.00
3 INT251236 Positive_regulation of Lvs 3 0.20 4.47 0.78 100.00
4 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 100.00
5 INT297421 Positive_regulation of Flg 1 0.40 1.6 0.53 100.00
6 INT316526 Localization of Flg 1 0.35 0.85 0.12 100.00
7 INT316527 Positive_regulation of Localization of Flg 1 0.22 0.86 0.12 100.00
8 INT251238 Gene_expression of Lvs 35 0.32 29.41 1.59 99.98
9 INT212839 Regulation of Lvs 4 0.03 1.98 0 99.80
10 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.74
11 INT43226 Gene_expression of Hivep3 75 0.71 30.53 21.14 99.48
12 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 99.34
13 INT206796 Positive_regulation of VAMP7 2 0.56 4.12 0.07 99.32
14 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 99.20
15 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 98.98
16 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 98.86
17 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 98.86
18 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 98.28
19 INT138799 Regulation of Gene_expression of Ppara 40 0.60 29.42 6.89 98.28
20 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 98.28
21 INT316524 Negative_regulation of Positive_regulation of Il13 2 0.34 1.87 0.45 96.56
22 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 96.56
23 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87 95.96
24 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 95.92
25 INT288184 Binding of Tlr1 8 0.29 4.73 0.4 95.92
26 INT177346 Negative_regulation of Positive_regulation of Il5 2 0.28 1.12 0.27 95.76
27 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 95.76
28 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 95.28
29 INT59319 Negative_regulation of Positive_regulation of Il4 6 0.57 3.48 1.17 95.28
30 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 94.88
31 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 94.52
32 INT304439 Positive_regulation of Xist 2 0.01 1.56 0.56 94.16
33 INT100671 Positive_regulation of Transcription of Hand2 2 0.36 0.81 0.23 94.16
34 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 94.16
35 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 93.84
36 INT120901 Positive_regulation of Gene_expression of Il13 36 0.57 31.63 13.36 93.84
37 INT103926 Gene_expression of Cd69 37 0.68 16.76 3.58 93.28
38 INT135022 Gene_expression of Cd14 79 0.76 36.37 10.63 92.88
39 INT189791 Negative_regulation of Gene_expression of Cd14 9 0.40 4.2 0.82 92.88
40 INT7535 Negative_regulation of Tlr4 111 0.56 56.84 21.37 92.68
41 INT130603 Binding of Timp1 9 0.35 8.52 3.04 92.40
42 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 92.32
43 INT140708 Gene_expression of Tlr1 10 0.50 5.24 0.72 91.84
44 INT258463 Negative_regulation of Lvs 6 0.18 4.56 0.08 90.24
45 INT204783 Positive_regulation of Gene_expression of Il23a 17 0.36 15.53 4.42 90.20
46 INT161220 Binding of Ccl2 17 0.46 17.63 4.94 89.84
47 INT135411 Gene_expression of Il23a 76 0.72 72.87 26.15 89.76
48 INT176606 Gene_expression of Stat6 9 0.65 6.87 0.77 89.56
49 INT304694 Binding of Lvs 4 0.15 3.71 0.16 89.24
50 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 88.80
51 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 88.80
52 INT178339 Binding of Cxcl1 17 0.36 5.14 2.04 88.40
53 INT135408 Transcription of Il17a 8 0.64 10.7 3.39 88.24
54 INT161515 Positive_regulation of Gene_expression of Il17a 50 0.64 41.52 13.82 88.16
55 INT170056 Binding of Cxcl10 11 0.45 12.72 5.32 87.44
56 INT60690 Positive_regulation of Gene_expression of Il12a 69 0.63 41.41 20.85 86.56
57 INT12325 Gene_expression of Plec 47 0.72 11.92 13.35 85.40
58 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 85.12
59 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 84.56
60 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 84.24
61 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 84.24
62 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 84.16
63 INT61076 Gene_expression of RHD 9 0.65 3.52 1.39 83.96
64 INT160563 Localization of Il17a 34 0.74 26.53 10.24 83.52
65 INT133172 Gene_expression of Il12b 98 0.75 52.16 10.68 82.56
66 INT251240 Positive_regulation of Pgm1 1 0.01 0.56 0 82.20
67 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 81.68
68 INT165737 Localization of RHD 1 0.01 0.08 0.26 81.44
69 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 80.64
70 INT812 Localization of INS 1026 0.81 515.6 145.31 80.64
71 INT278546 Transcription of GNPTAB 3 0.03 2.19 1.1 80.48
72 INT135406 Transcription of Il23a 3 0.32 3.15 1.31 80.48
73 INT204767 Negative_regulation of Transcription of Il23a 2 0.19 2.24 0.62 80.48
74 INT165736 Gene_expression of TRAPPC1 1 0.03 0.08 0.25 80.32
75 INT11807 Gene_expression of Il2 266 0.78 112 64.97 80.04
76 INT165738 Localization of TRAPPC1 1 0.04 0.08 0.26 79.56
77 INT204771 Negative_regulation of Transcription of Il17a 2 0.39 2.31 0.63 79.44
78 INT263524 Binding of Rhof 1 0.03 0.16 0.09 76.48
79 INT72747 Localization of IgG 55 0.53 30.88 4.19 75.44
80 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 75.36
81 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 75.04
82 INT57252 Negative_regulation of PGR 22 0.43 12.95 3.33 69.92
83 INT96068 Positive_regulation of Timp1 30 0.58 23.94 8.17 64.16
84 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 63.52
85 INT314090 Regulation of Gene_expression of Lvs 3 0.18 3.44 0 62.56
86 INT227973 Gene_expression of Gm2404 9 0.10 4.21 0 62.12
87 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 61.28
88 INT38670 Positive_regulation of Gene_expression of KRT20 68 0.69 23.25 5.55 61.28
89 INT251239 Positive_regulation of Gene_expression of Lvs 4 0.21 7.64 0.86 58.36
90 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 58.28
91 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 58.28
92 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 55.96
93 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 55.48
94 INT178711 Protein_catabolism of Tlr4 15 0.84 6.75 3.19 54.88
95 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 54.76
96 INT174423 Gene_expression of Smcp 39 0.48 29.45 6.06 54.48
97 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 54.32
98 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 50.04
99 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 50.00
100 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 50.00
101 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 50.00
102 INT157622 Positive_regulation of Localization of Tlr4 34 0.48 22.63 5.09 50.00
103 INT181186 Binding of Rxra 78 0.35 14.93 4.87 50.00
104 INT38043 Gene_expression of Cps1 6 0.56 0.82 1.46 50.00
105 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58 50.00
106 INT186057 Binding of CCND1 8 0.31 5.92 0.26 50.00
107 INT212845 Negative_regulation of DR1 2 0.12 0.41 0.15 50.00
108 INT196324 Localization of Cyp2b10 5 0.73 2.81 0.13 50.00
109 INT223372 Gene_expression of HSPA1B 2 0.58 1.03 0.03 50.00
110 INT297420 Gene_expression of Tifa 1 0.15 0.71 0.03 50.00
111 INT251237 Localization of Lvs 1 0.08 0.36 0 50.00
112 INT287709 Binding of Cyp2b10 2 0.36 1.98 0 50.00
113 INT297429 Localization of TIFA 1 0.73 0.53 0 50.00
114 INT243034 Positive_regulation of Rarb 1 0.04 4.07 2.52 47.60
115 INT227970 Negative_regulation of Gm2404 1 0.02 0.68 0 47.32
116 INT190081 Gene_expression of Abca1 21 0.65 18.18 2.45 45.56
117 INT220861 Positive_regulation of Mmp8 14 0.50 12.21 4.6 40.96
118 INT341821 Positive_regulation of Gene_expression of Rax 1 0.05 0.38 0 39.80
119 INT341822 Positive_regulation of Rax 1 0.05 0.38 0 39.80
120 INT279598 Gene_expression of Rax 3 0.07 2.91 0.15 39.28
121 INT243032 Gene_expression of Rarb 3 0.42 4.47 0.73 37.60
122 INT227971 Positive_regulation of Gm2404 3 0.06 0.66 0 35.40
123 INT192406 Regulation of Ighm 16 0.31 5.58 0.29 32.64
124 INT278194 Protein_catabolism of Il4 2 0.57 1.12 0.3 27.80
125 INT139679 Positive_regulation of Ighg2b 11 0.55 10.57 1.1 27.20
126 INT46169 Transcription of IgG 14 0.67 7.71 1.01 26.76
127 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43 26.56
128 INT10870 Regulation of IgG 67 0.59 43.27 12.74 25.04
129 INT61148 Regulation of Cd79a 13 0.51 6.95 1.9 24.08
130 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 24.00
131 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 24.00
132 INT155780 Gene_expression of Mmp8 19 0.77 15.85 6.33 24.00
133 INT184257 Positive_regulation of Gene_expression of Mmp8 7 0.49 6.32 2.74 24.00
134 INT173519 Positive_regulation of Localization of IFNA1 27 0.49 24.48 3.9 22.28
135 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 21.80
136 INT20215 Localization of IgG2a 4 0.78 2.2 0.72 21.80
137 INT229681 Negative_regulation of Plec 2 0.39 1.71 0.3 18.64
138 INT282119 Negative_regulation of Negative_regulation of Plec 1 0.20 0.45 0 18.64
139 INT319365 Regulation of Gene_expression of Smcp 3 0.32 0.53 0 13.36
140 INT14238 Positive_regulation of Cd69 19 0.60 17.75 6.07 9.80
141 INT15594 Positive_regulation of Ldha 3 0.26 0.96 1.14 9.76
142 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 9.24
143 INT243031 Positive_regulation of Positive_regulation of Rarb 1 0.03 1.34 0.58 9.16
144 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 7.28
145 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 6.72
146 INT282120 Negative_regulation of Positive_regulation of Alb 1 0.17 0.48 0 6.72
147 INT168600 Binding of Mmp9 14 0.44 12.79 6.92 5.60
148 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
149 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
150 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
151 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
152 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
153 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
154 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
155 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
156 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
157 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
158 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
159 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 5.00
160 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
161 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
162 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 5.00
163 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
164 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
165 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
166 INT117223 Gene_expression of TLR4 348 0.78 206.18 54.42 5.00
167 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
168 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
169 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 5.00
170 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
171 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
172 INT13354 Transcription of TNF 108 0.72 85.81 42.32 5.00
173 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
174 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2 5.00
175 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
176 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 5.00
177 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
178 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
179 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56 5.00
180 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
181 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
182 INT59449 Negative_regulation of Timp1 76 0.42 54.86 26.99 5.00
183 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
184 INT20462 Binding of ESR1 210 0.44 102.7 26.34 5.00
185 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 5.00
186 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 5.00
187 INT5988 Localization of Dbi 74 0.81 17.52 24.09 5.00
188 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 5.00
189 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 5.00
190 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
191 INT88949 Positive_regulation of Il12a 79 0.60 47.68 19.98 5.00
192 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
193 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
194 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
195 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
196 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 5.00
197 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 5.00
198 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 5.00
199 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
200 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox