D:Funnel Chest

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pChart

Disease Term
Synonyms Chest Funnel, Chests Funnel, Excavatum Pectus, Funnel Chests, Pectus Excavatum
Documents 97
Hot Single Events 5
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Funnel Chest. They are ordered first by their relevance to Funnel Chest and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT180200 Binding of BCAR1 and MMVP1 1 0.11 8.57 0.08 87.24
2 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 28.44
3 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
4 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
5 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
6 INT307306 Gene_expression of COMP Positive_regulation of CALR 1 0.27 0.99 0 5.00
7 INT307305 Gene_expression of COMP Positive_regulation of Positive_regulation of CALR 1 0.27 0.41 0 5.00
8 INT307307 COMP Positive_regulation of EREG 1 0.01 0.46 0 5.00
9 INT307309 Binding of CALR and EREG 1 0.00 0.83 0 5.00
10 INT307310 Binding of CALR and COMP 1 0.28 0.82 0 5.00
11 INT307308 Binding of COMP and EREG 1 0.01 0.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Funnel Chest. They are ordered first by their pain relevance and then by number of times they were reported in Funnel Chest. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT9973 Binding of MMVP1 14 0.48 22.66 1.79 97.00
2 INT1703 Regulation of PCa 52 0.52 23.65 20.6 93.32
3 INT180201 Regulation of MMVP1 1 0.08 1.57 0.11 91.56
4 INT27753 Positive_regulation of MMVP1 5 0.43 7.1 0.74 90.48
5 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 82.72
6 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 78.16
7 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 74.08
8 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 68.64
9 INT269104 Positive_regulation of AOX1 1 0.19 4.25 0.4 63.80
10 INT82829 Gene_expression of COMP 104 0.78 57 9.81 61.12
11 INT269102 Binding of AOX1 1 0.21 1.99 0.35 47.92
12 INT198406 Localization of C2 5 0.65 1.42 1.01 47.68
13 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 37.64
14 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 16.24
15 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 12.72
16 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
17 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
18 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
19 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
20 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
21 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
22 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 5.00
23 INT17997 Positive_regulation of Mch 23 0.49 12.71 6.67 5.00
24 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 5.00
25 INT38595 Localization of BCAR1 8 0.73 2.9 6.25 5.00
26 INT59555 Binding of RYR1 39 0.42 8.65 4.92 5.00
27 INT88545 Localization of MMRN1 21 0.78 16.67 4.01 5.00
28 INT162258 Negative_regulation of Gene_expression of COMP 35 0.58 19.14 3.55 5.00
29 INT118095 Regulation of COMP 7 0.43 9.69 3.33 5.00
30 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
31 INT279122 Regulation of Gene_expression of COMP 3 0.39 8.82 3.19 5.00
32 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 5.00
33 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
34 INT200470 Positive_regulation of Gene_expression of COMP 13 0.69 13.73 2.93 5.00
35 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 5.00
36 INT169987 Transcription of GOPC 45 0.60 21.88 2.61 5.00
37 INT54555 Negative_regulation of CALR 10 0.41 4.41 2.4 5.00
38 INT3590 Positive_regulation of AVL9 7 0.40 7.94 2.36 5.00
39 INT131456 Negative_regulation of MMRN1 14 0.19 9.49 2.29 5.00
40 INT8052 Negative_regulation of COMP 46 0.58 13.73 2.22 5.00
41 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 5.00
42 INT11713 Localization of RYR1 22 0.76 10.42 1.64 5.00
43 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54 5.00
44 INT135879 Localization of MATN3 12 0.80 10.31 1.44 5.00
45 INT118097 Localization of COMP 18 0.70 9.99 1.42 5.00
46 INT55305 Regulation of RYR1 14 0.45 5.27 1.33 5.00
47 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 5.00
48 INT11367 Localization of MB 9 0.78 9.34 1.24 5.00
49 INT97909 Binding of COMP 13 0.37 5.98 1.22 5.00
50 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 5.00
51 INT131844 Gene_expression of MATN3 12 0.78 9.65 0.92 5.00
52 INT118098 Protein_catabolism of COMP 5 0.66 2.76 0.9 5.00
53 INT89340 Positive_regulation of EREG 5 0.69 4.98 0.77 5.00
54 INT279130 Negative_regulation of Localization of COMP 5 0.51 3.75 0.69 5.00
55 INT207780 Positive_regulation of NMS 2 0.28 3.2 0.61 5.00
56 INT162801 Localization of CALR 7 0.73 8.69 0.6 5.00
57 INT207778 Positive_regulation of Binding of Ap3d1 1 0.06 1.26 0.52 5.00
58 INT269105 Localization of AOX1 1 0.31 2.16 0.5 5.00
59 INT269103 Gene_expression of AOX1 2 0.26 1.97 0.46 5.00
60 INT89341 Gene_expression of EREG 3 0.78 2.38 0.38 5.00
61 INT195871 Positive_regulation of Gene_expression of CALR 9 0.29 3 0.27 5.00
62 INT49908 Regulation of Gene_expression of RYR1 3 0.45 0.32 0.19 5.00
63 INT202591 Regulation of AVL9 2 0.02 1.58 0.19 5.00
64 INT221002 Transcription of COMP 2 0.60 1.79 0.16 5.00
65 INT207779 Localization of Ap3d1 1 0.11 3.16 0.14 5.00
66 INT200984 Positive_regulation of FIBP 2 0.12 1.12 0.14 5.00
67 INT195744 Gene_expression of XIST 3 0.65 1.61 0.12 5.00
68 INT307328 Negative_regulation of Positive_regulation of FIBP 1 0.01 0.95 0.06 5.00
69 INT245751 Gene_expression of COL9A2 4 0.65 1.83 0.04 5.00
70 INT307330 Negative_regulation of MATN3 1 0.29 0.57 0.04 5.00
71 INT307323 Negative_regulation of Gene_expression of COL9A2 1 0.06 0.74 0.04 5.00
72 INT207781 Gene_expression of CACNA1S 3 0.63 0.9 0.03 5.00
73 INT307325 Negative_regulation of Gene_expression of EREG 1 0.01 0.31 0.03 5.00
74 INT207782 Binding of CACNA1S 1 0.30 0.53 0.03 5.00
75 INT267892 Gene_expression of Prkag2 3 0.62 3.59 0 5.00
76 INT307327 Negative_regulation of Localization of COL9A2 1 0.06 0.35 0 5.00
77 INT279128 Negative_regulation of Localization of MATN3 2 0.43 0.92 0 5.00
78 INT307333 Protein_catabolism of ZNF70 1 0.01 0.68 0 5.00
79 INT315136 Gene_expression of TSIX 1 0.19 0.52 0 5.00
80 INT307324 Positive_regulation of Positive_regulation of CALR 1 0.25 0.36 0 5.00
81 INT307322 Negative_regulation of Localization of MMRN1 1 0.04 0.18 0 5.00
82 INT307329 Negative_regulation of Positive_regulation of COMP 1 0.38 0.12 0 5.00
83 INT307331 Negative_regulation of Positive_regulation of CALR 1 0.29 0.36 0 5.00
84 INT279126 Localization of COL9A2 2 0.64 0.77 0 5.00
85 INT307326 Negative_regulation of Gene_expression of CALR 3 0.25 1.78 0 5.00
86 INT180202 Localization of MMVP1 1 0.25 1.69 0 5.00
87 INT307332 Negative_regulation of Localization of CALR 1 0.29 0.72 0 5.00
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