D:Gait Ataxia

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Disease Term
Synonyms Ataxia Cerebellar Gait, Ataxia Gait, Ataxia Of Gait, Ataxia Sensory Gait, Ataxias Cerebellar Gait, Ataxias Gait, Ataxias Sensory Gait, Cerebellar Gait, Cerebellar Gait Ataxia, Cerebellar Gait Ataxias, CEREBELLAR GAITS
Documents 82
Hot Single Events 12
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gait Ataxia. They are ordered first by their relevance to Gait Ataxia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 41.84
2 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
3 INT288162 Igh-Dex Positive_regulation of Gopc 1 0.02 0.63 0.41 5.00
4 INT288168 Binding of Jun and Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.01 0.52 0.36 5.00
5 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35 5.00
6 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35 5.00
7 INT288165 Binding of Jun and Ugcg 1 0.02 0.45 0.32 5.00
8 INT288166 Binding of gr and Ugcg 1 0.07 0.45 0.31 5.00
9 INT288163 Binding of gr and Igh-Dex 1 0.03 0.18 0.27 5.00
10 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
11 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
12 INT251944 Binding of GH1 and PRNP 1 0.09 1.14 0.05 5.00
13 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
14 INT329013 Binding of LITAF and Nedd4 1 0.15 1.4 0 5.00
15 INT329004 Binding of MPZ and RNF123 1 0.00 0.7 0 5.00
16 INT329012 Binding of MPZ and Nedd4 1 0.03 0.7 0 5.00
17 INT329008 Binding of LITAF and RNF123 1 0.01 1.39 0 5.00
18 INT302675 Binding of OPA1 and PLAA 1 0.15 0.73 0 5.00
19 INT329005 Binding of TSG101 and LITAF 1 0.04 1.41 0 5.00
20 INT329007 Binding of MPZ and TSG101 1 0.01 0.71 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gait Ataxia. They are ordered first by their pain relevance and then by number of times they were reported in Gait Ataxia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 92.28
2 INT200132 Regulation of Ercc2 2 0.36 4.56 0.05 90.16
3 INT200135 Regulation of Ercc3 2 0.34 3.47 0.05 90.16
4 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 88.80
5 INT200136 Negative_regulation of ERCC2 1 0.37 1.91 0.07 88.72
6 INT120135 Negative_regulation of Hace1 1 0.37 1.12 0 88.20
7 INT176180 Negative_regulation of Nr1h2 6 0.16 7.47 0.69 87.64
8 INT70145 Gene_expression of Trav6-3 136 0.76 69.6 18.05 87.64
9 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84 87.64
10 INT152045 Negative_regulation of Trav6-3 10 0.57 6.42 1.16 87.64
11 INT75299 Binding of Atxn3 8 0.43 5.3 0.26 86.36
12 INT109810 Localization of DCAF12L1 1 0.74 0.77 0.47 80.56
13 INT677 Positive_regulation of CST3 20 0.67 17.47 6 74.68
14 INT14500 Positive_regulation of Gene_expression of CST3 9 0.67 7.46 1.87 74.68
15 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16 73.88
16 INT64700 Binding of Nf1 14 0.45 15.24 2.29 72.80
17 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 59.40
18 INT217 Negative_regulation of Th 134 0.59 26.83 62.63 59.40
19 INT162 Regulation of Prl 794 0.62 165.01 322.24 54.64
20 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 54.64
21 INT200133 Negative_regulation of Xpa 5 0.58 9.85 0.09 53.88
22 INT199656 Binding of Pnkp 1 0.07 1.36 0.07 53.88
23 INT194332 Localization of MFN2 2 0.74 1.45 0.15 50.56
24 INT65697 Positive_regulation of GRIN3B 23 0.69 12.52 13.78 47.28
25 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25 44.80
26 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 34.80
27 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 26.36
28 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 25.80
29 INT302703 Binding of PLAA 1 0.13 0.87 0.15 20.44
30 INT309249 Regulation of OGDHL 1 0.01 0.6 0.3 16.04
31 INT309251 Gene_expression of OGDHL 1 0.01 0.64 0.29 14.20
32 INT195203 Binding of Tenc1 14 0.32 13.97 8.28 9.48
33 INT110748 Transcription of Tenc1 5 0.30 3.06 0.48 6.32
34 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
35 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
36 INT2910 Regulation of Abat 169 0.62 36.95 153.53 5.00
37 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
38 INT1530 Regulation of Gh 382 0.61 115.96 112.47 5.00
39 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 5.00
40 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
41 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
42 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 5.00
43 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 5.00
44 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
45 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
46 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 5.00
47 INT1487 Regulation of Cpe 68 0.62 10.24 52.91 5.00
48 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
49 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63 5.00
50 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
51 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
52 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
53 INT11439 Positive_regulation of Csf2 105 0.69 62.63 37.77 5.00
54 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
55 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 5.00
56 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 5.00
57 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
58 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
59 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 5.00
60 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
61 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 5.00
62 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
63 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 5.00
64 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 5.00
65 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
66 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 5.00
67 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
68 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
69 INT8580 Gene_expression of ELANE 132 0.75 62.98 21.79 5.00
70 INT14700 Regulation of IFNA1 111 0.45 66.16 21.52 5.00
71 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
72 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
73 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 5.00
74 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 5.00
75 INT3060 Negative_regulation of Bche 94 0.59 46.75 18.51 5.00
76 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 5.00
77 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 5.00
78 INT152730 Positive_regulation of S100a8 48 0.68 47.67 15.4 5.00
79 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 5.00
80 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53 5.00
81 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 5.00
82 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
83 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
84 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 5.00
85 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 5.00
86 INT3521 Regulation of Csf2 38 0.54 11.09 12.73 5.00
87 INT49975 Binding of SLC6A3 34 0.47 9.86 12.41 5.00
88 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 5.00
89 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 5.00
90 INT9945 Negative_regulation of Csf2 35 0.51 17.85 11.22 5.00
91 INT32007 Gene_expression of ECT 56 0.62 18.94 11.13 5.00
92 INT53201 Negative_regulation of gr 35 0.50 17.76 10.62 5.00
93 INT140338 Negative_regulation of Gene_expression of Il17a 34 0.46 23.82 9.87 5.00
94 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71 5.00
95 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51 5.00
96 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
97 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
98 INT156874 Positive_regulation of Gene_expression of S100a8 26 0.49 32.8 8.99 5.00
99 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 5.00
100 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62 5.00
101 INT17041 Gene_expression of PER1 24 0.66 5.31 7.12 5.00
102 INT55957 Positive_regulation of PRNP 57 0.67 37.87 7.11 5.00
103 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88 5.00
104 INT10785 Gene_expression of Prl 35 0.78 20.64 6.7 5.00
105 INT74865 Gene_expression of Igh-Dex 16 0.22 8.95 6.59 5.00
106 INT49212 Negative_regulation of GAD1 23 0.59 22.15 6.54 5.00
107 INT93061 Binding of gr 31 0.48 10.93 6.45 5.00
108 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43 5.00
109 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27 5.00
110 INT57232 Binding of Casp3 22 0.36 9.42 6.2 5.00
111 INT28088 Binding of Alb 34 0.47 11.06 5.48 5.00
112 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 5.00
113 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 5.00
114 INT18543 Negative_regulation of ECT 20 0.37 8.4 5.25 5.00
115 INT10100 Binding of ELANE 22 0.47 15.32 5.19 5.00
116 INT33854 Localization of OPA1 19 0.65 10.55 5.04 5.00
117 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 5.00
118 INT49405 Gene_expression of Itgal 40 0.75 27.3 4.8 5.00
119 INT51030 Negative_regulation of LMOD1 9 0.44 5.83 4.58 5.00
120 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 5.00
121 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 5.00
122 INT48411 Gene_expression of Cd44 35 0.77 27.05 4.29 5.00
123 INT71868 Regulation of Tenc1 9 0.52 10.73 4.09 5.00
124 INT32933 Gene_expression of GNAS 57 0.32 10.58 4.03 5.00
125 INT3405 Gene_expression of BCAR1 14 0.71 8.89 4.02 5.00
126 INT45147 Gene_expression of C2 21 0.58 6.18 3.98 5.00
127 INT19104 Regulation of Gene_expression of Gh 24 0.40 8.42 3.88 5.00
128 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 5.00
129 INT32464 Regulation of Mmp13 12 0.44 6.46 3.61 5.00
130 INT191669 Localization of Igh-Dex 8 0.26 4.35 3.54 5.00
131 INT80224 Regulation of Hmox1 19 0.32 10.53 3.52 5.00
132 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 5.00
133 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 5.00
134 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41 5.00
135 INT1727 Gene_expression of Cndp2 22 0.74 4.28 3.34 5.00
136 INT102634 Transcription of Hmox1 22 0.62 4.5 3.3 5.00
137 INT53520 Binding of Igh-Dex 4 0.28 0.47 3.25 5.00
138 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24 5.00
139 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 5.00
140 INT151123 Negative_regulation of Gene_expression of Csf2 21 0.53 21.76 3.22 5.00
141 INT25674 Positive_regulation of Gene_expression of ELANE 16 0.60 7.46 3.12 5.00
142 INT59905 Gene_expression of Ghr 29 0.63 9.25 2.97 5.00
143 INT5913 Binding of OPA1 12 0.41 9.33 2.92 5.00
144 INT45971 Negative_regulation of GOT1 9 0.51 6.2 2.84 5.00
145 INT205596 Negative_regulation of COQ10A 22 0.51 15.61 2.77 5.00
146 INT115300 Negative_regulation of Napa 7 0.23 1 2.68 5.00
147 INT50080 Binding of APOE 38 0.45 29.61 2.67 5.00
148 INT205594 Gene_expression of COQ10A 19 0.67 12.53 2.56 5.00
149 INT18848 Localization of LMOD1 5 0.69 1 2.49 5.00
150 INT53202 Negative_regulation of Positive_regulation of gr 6 0.46 2.35 2.27 5.00
151 INT161575 Localization of CACNA1A 4 0.75 5.28 2.26 5.00
152 INT164248 Positive_regulation of MPZ 18 0.67 24.54 2.16 5.00
153 INT114330 Binding of MPZ 21 0.32 25.58 2.14 5.00
154 INT108250 Regulation of Prdx2 5 0.25 2.02 2.08 5.00
155 INT167203 Binding of PRNP 25 0.48 20.09 1.84 5.00
156 INT122895 Transcription of DIO2 3 0.52 0.91 1.73 5.00
157 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69 5.00
158 INT97062 Binding of PML 10 0.41 11.63 1.65 5.00
159 INT31616 Protein_catabolism of DNM2 5 0.75 1.61 1.63 5.00
160 INT69125 Gene_expression of Prlr 6 0.78 2 1.58 5.00
161 INT309257 Transcription of LMOD1 3 0.36 1.71 1.57 5.00
162 INT144380 Gene_expression of SYNE1 12 0.58 6.99 1.55 5.00
163 INT17094 Negative_regulation of SLC25A4 3 0.41 3.82 1.52 5.00
164 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41 5.00
165 INT90491 Binding of Igf1 25 0.44 9.75 1.36 5.00
166 INT151540 Regulation of Fmr1 8 0.59 6.08 1.34 5.00
167 INT82932 Transcription of AR 14 0.67 5.75 1.34 5.00
168 INT3404 Binding of BCAR1 10 0.33 7.97 1.33 5.00
169 INT152728 Negative_regulation of Positive_regulation of S100a8 4 0.43 3.96 1.29 5.00
170 INT74550 Negative_regulation of SUCLA2 5 0.41 3.6 1.24 5.00
171 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21 5.00
172 INT16013 Gene_expression of Rac1 52 0.75 23.79 1.21 5.00
173 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 5.00
174 INT172855 Binding of Bcl2 37 0.32 23.41 1.09 5.00
175 INT175389 Positive_regulation of Ugcg 9 0.32 8.79 1.09 5.00
176 INT118054 Regulation of ARMC9 23 0.34 11.32 1.06 5.00
177 INT82969 Positive_regulation of Hltf 2 0.02 0.28 1.03 5.00
178 INT71916 Gene_expression of TTN 9 0.75 1.69 0.97 5.00
179 INT17574 Binding of CISH 23 0.31 4.3 0.93 5.00
180 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91 5.00
181 INT159409 Gene_expression of PLAA 2 0.54 6.14 0.89 5.00
182 INT94563 Gene_expression of H2-Q10 7 0.42 7 0.88 5.00
183 INT170813 Gene_expression of Prdm6 11 0.65 4.35 0.88 5.00
184 INT11198 Negative_regulation of Gclc 3 0.59 0.49 0.87 5.00
185 INT52460 Localization of SUCLA2 5 0.67 2.5 0.86 5.00
186 INT126566 Binding of Ifnb1 3 0.31 2.43 0.85 5.00
187 INT155052 Regulation of Gene_expression of Csf2 6 0.37 7.75 0.8 5.00
188 INT17246 Negative_regulation of POLG 16 0.56 9.69 0.79 5.00
189 INT50687 Gene_expression of Aldoc 6 0.78 0.17 0.78 5.00
190 INT117043 Gene_expression of Itga1 4 0.37 3.3 0.77 5.00
191 INT199649 Gene_expression of Fxn 12 0.72 20.9 0.74 5.00
192 INT129630 Regulation of Sod1 6 0.44 4.94 0.73 5.00
193 INT246552 Transcription of Fmr1 11 0.72 6.72 0.71 5.00
194 INT187096 Negative_regulation of Cd44 6 0.30 5.92 0.7 5.00
195 INT195202 Negative_regulation of Gene_expression of Tenc1 7 0.24 3.76 0.62 5.00
196 INT649 Positive_regulation of Afp 10 0.55 6.5 0.62 5.00
197 INT188137 Regulation of CISH 7 0.04 0.97 0.6 5.00
198 INT288158 Negative_regulation of Gene_expression of Cd44 5 0.30 5.73 0.59 5.00
199 INT309253 Negative_regulation of Transcription of LMOD1 1 0.03 0.2 0.57 5.00
200 INT19047 Localization of SLC25A4 5 0.73 2.73 0.57 5.00
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