D:Gallstones

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pChart

Disease Term
Synonyms BILIARY CALCULI, Biliary Calculi Common Bile Duct, Calculi Biliary, Choledocholothiasis, Cholelithiasis, Cholestasis, COMMON BILE DUCT CALCULI, Common Bile Duct Gall Stones, Common Bile Duct Gallstones, GALL STONE, GALL STONES
Documents 2353
Hot Single Events 200
Hot Interactions 14

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gallstones. They are ordered first by their relevance to Gallstones and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT104702 KNG1 Negative_regulation of Anpep 1 0.11 0.47 0.19 96.56
2 INT58249 CCK Positive_regulation of Regulation of GAST 1 0.48 0.86 0.5 95.80
3 INT142437 Urb1 Negative_regulation of Faah 3 0.41 2.12 1.66 95.72
4 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 95.20
5 INT290678 Binding of CHI3L1 and KRTAP19-9P 1 0.08 1.2 0 94.80
6 INT290679 Binding of SPP1 and KRTAP19-9P 1 0.05 1.2 0 94.80
7 INT153154 OPN1MW Regulation of PTPRF 1 0.03 0.51 0.14 94.64
8 INT229420 Atp6v0a2 Negative_regulation of Ros1 1 0.00 1.13 0.04 93.76
9 INT215955 Binding of alp and Cys1 1 0.00 0.95 0.22 93.76
10 INT229422 Atp6v0a2 Regulation of Mpo 1 0.03 3.39 0.15 88.76
11 INT278610 CDCA2 Negative_regulation of NR1H4 1 0.01 0.62 0.13 88.76
12 INT229421 Atp6v0a2 Negative_regulation of Positive_regulation of Mpo 1 0.03 2.8 0.16 85.68
13 INT177359 Serpinc1 Positive_regulation of CSRP1 1 0.00 0.97 0.72 82.56
14 INT229433 Atp6v0a2 Negative_regulation of Positive_regulation of Gpt 1 0.00 0.32 0 80.08
15 INT232897 Binding of Rab27a and SAMSN1 1 0.00 0.73 0.08 79.00
16 INT221085 GHRH Positive_regulation of Gene_expression of IGF1 2 0.56 1.47 0.41 77.92
17 INT283520 Binding of DLAT and Pain1 1 0.27 0.65 0.22 74.36
18 INT229419 Atp6v0a2 Regulation of Cat 1 0.01 1.73 0.06 74.24
19 INT229423 Atp6v0a2 Regulation of Rab38 1 0.00 1.73 0.06 73.44
20 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 68.48
21 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04 66.64
22 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 65.56
23 INT191240 SAE1 Regulation of Localization of INS 1 0.08 1.15 0.3 65.48
24 INT175596 Binding of ACAT1 and HGF 1 0.01 1.58 0.18 63.92
25 INT316544 BCL2L11 Regulation of INS 1 0.00 1.36 0.77 61.16
26 INT214481 ROS1 Negative_regulation of Gene_expression of INS 1 0.00 0.37 0.22 60.16
27 INT227303 Zbp1 Regulation of Transcription of Baat 1 0.09 1.43 0.08 59.44
28 INT227301 Zbp1 Regulation of Transcription of Ucp1 1 0.19 1.42 0.08 59.44
29 INT227304 Zbp1 Regulation of Transcription of Ucp2 1 0.17 1.43 0.08 59.44
30 INT303845 Binding of PON1 and Pon1 1 0.01 1.33 0 58.60
31 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 57.84
32 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 51.96
33 INT283463 Binding of DLAT and GAGE4 1 0.00 1.1 0.03 51.44
34 INT217666 ADIPOQ Regulation of Gene_expression of INS 1 0.03 1.99 0.05 50.56
35 INT290675 SPP1 Positive_regulation of Gene_expression of VEGFA 1 0.16 2.37 0 50.48
36 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 49.48
37 INT283461 Binding of IL2 and SLC4A2 1 0.01 0.98 0 48.16
38 INT214380 Binding of IL1A and PRTN3 1 0.00 0.94 0.18 43.20
39 INT252787 Binding of FCGR3B and ROS1 1 0.06 0.58 0.2 43.04
40 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0 40.08
41 INT278611 Binding of CASR and SULT2A1 1 0.03 0 0.07 38.88
42 INT278602 Binding of SULT2A1 and NR1I3 1 0.04 0 0.07 38.88
43 INT278600 Binding of CASR and SULT2A1 Positive_regulation of SULT2A1 1 0.03 0 0.07 38.88
44 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 36.68
45 INT278684 Binding of NR1I3 and Rxra 1 0.00 0 0.07 35.60
46 INT278685 Binding of CASR and Rxra 1 0.00 0 0.07 35.60
47 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28 29.12
48 INT303446 Timp1 Negative_regulation of Mmp2 1 0.19 0.33 0.31 26.96
49 INT352521 Cnn1 Positive_regulation of Cp 1 0.00 1.45 0.5 25.92
50 INT274625 OPN1MW Positive_regulation of SOD1 1 0.19 0.29 0.5 20.68
51 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41 18.84
52 INT215878 Eif2ak3 Positive_regulation of Localization of Ins1 1 0.04 0.96 0.06 18.72
53 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4 17.40
54 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 16.32
55 INT229424 Atp6v0a2 Regulation of Fig4 1 0.00 1.14 0.1 13.32
56 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05 11.04
57 INT339702 TRO Positive_regulation of CD36 1 0.08 1.06 0 9.96
58 INT229418 Mpo Positive_regulation of Sod1 1 0.20 0.71 0 8.40
59 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 5.60
60 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
61 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
62 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38 5.00
63 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
64 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
65 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
66 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
67 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
68 INT215100 Binding of Hmgb1 and Tlr4 5 0.29 3.21 1.68 5.00
69 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
70 INT71176 Binding of ICAM1 and ITGB2 4 0.21 4.93 1.07 5.00
71 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04 5.00
72 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
73 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
74 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96 5.00
75 INT249347 Binding of FOS and JUN 4 0.19 6.15 0.89 5.00
76 INT303656 SST Negative_regulation of Localization of GAST 1 0.12 1.45 0.82 5.00
77 INT239671 Binding of Ccl2 and Gtf3a 1 0.02 1.34 0.79 5.00
78 INT331599 Tlr9 Positive_regulation of Gene_expression of Il6 1 0.03 1.8 0.73 5.00
79 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
80 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 5.00
81 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64 5.00
82 INT252772 ELANE Regulation of Gene_expression of CCL2 1 0.05 2.16 0.62 5.00
83 INT252826 ROS1 Regulation of Gene_expression of CCL2 1 0.20 2.17 0.62 5.00
84 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57 5.00
85 INT303654 Binding of SST and SSTR5 1 0.22 0.46 0.57 5.00
86 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54 5.00
87 INT177358 Ptger1 Positive_regulation of Localization of AMY2A 1 0.00 0.56 0.54 5.00
88 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54 5.00
89 INT177357 Ptger1 Positive_regulation of Gene_expression of AMY2A 1 0.00 0.56 0.54 5.00
90 INT253767 Binding of Hmgb1 and Tlr9 2 0.12 1.78 0.52 5.00
91 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
92 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47 5.00
93 INT303651 Binding of SSTR2 and SSTR5 1 0.24 0.23 0.45 5.00
94 INT303444 Timp1 Regulation of Fig4 1 0.15 0.43 0.39 5.00
95 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37 5.00
96 INT316545 Binding of IGF1 and SST 1 0.06 0.45 0.37 5.00
97 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
98 INT226785 Angpt2 Positive_regulation of Localization of Lep 1 0.01 1.65 0.36 5.00
99 INT236955 Binding of Cxcr5 and Cxcl13 1 0.28 2.26 0.34 5.00
100 INT311228 DPP4 Negative_regulation of Localization of GLP1R 1 0.31 1.25 0.32 5.00
101 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
102 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29 5.00
103 INT228530 Gopc Positive_regulation of Gene_expression of Nos2 2 0.22 0.67 0.28 5.00
104 INT252806 F2 Positive_regulation of Gene_expression of CCL2 1 0.01 0.8 0.27 5.00
105 INT252794 Binding of IL8 and TNF 1 0.02 0.75 0.25 5.00
106 INT252795 IL8 Positive_regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
107 INT252815 Binding of CCL5 and TNF 1 0.02 0.75 0.25 5.00
108 INT252822 CCL2 Positive_regulation of Positive_regulation of FOS 1 0.04 0.75 0.25 5.00
109 INT252804 TNF Regulation of Positive_regulation of FOS 1 0.01 0.76 0.25 5.00
110 INT252786 CCL2 Regulation of Positive_regulation of FOS 1 0.05 0.75 0.25 5.00
111 INT252816 IL8 Regulation of Positive_regulation of FOS 1 0.01 0.75 0.25 5.00
112 INT252793 TNF Positive_regulation of Positive_regulation of FOS 1 0.02 0.76 0.25 5.00
113 INT335028 Fgf15 Positive_regulation of Fgfr4 1 0.40 0.31 0.25 5.00
114 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
115 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24 5.00
116 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24 5.00
117 INT252777 ROS1 Positive_regulation of Gene_expression of CCL2 1 0.31 0.77 0.23 5.00
118 INT255044 GLP1R Positive_regulation of Localization of INS 3 0.49 1.47 0.22 5.00
119 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 5.00
120 INT335025 Gm7647 Positive_regulation of Gene_expression of Fgf21 1 0.01 0.29 0.21 5.00
121 INT331602 Binding of SSRP1 and Tlr4 1 0.03 0.9 0.21 5.00
122 INT189321 Binding of Apoa1 and Hdlcl1 1 0.00 0.68 0.2 5.00
123 INT228532 Positive_regulation of Gopc Positive_regulation of Ros1 1 0.03 0.55 0.2 5.00
124 INT228531 Gopc Positive_regulation of Ros1 1 0.03 0.55 0.2 5.00
125 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2 5.00
126 INT252814 ELANE Positive_regulation of Positive_regulation of CCL2 1 0.05 0.8 0.2 5.00
127 INT266646 HMOX2 Regulation of Gene_expression of Hmox1 1 0.00 0.87 0.2 5.00
128 INT252782 ROS1 Positive_regulation of Positive_regulation of CCL2 1 0.22 0.8 0.2 5.00
129 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19 5.00
130 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19 5.00
131 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
132 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
133 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19 5.00
134 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
135 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18 5.00
136 INT251492 Binding of HSPD1 and SOD1 1 0.02 1.45 0.18 5.00
137 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 5.00
138 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18 5.00
139 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18 5.00
140 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18 5.00
141 INT316072 Binding of Cd3e and Ncam1 1 0.01 0.4 0.18 5.00
142 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17 5.00
143 INT316074 Binding of Cd19 and Cd3e 1 0.02 0.39 0.17 5.00
144 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
145 INT278609 PPARA Positive_regulation of Gene_expression of SULT2A1 1 0.33 0 0.17 5.00
146 INT311226 DPP4 Negative_regulation of GLP1R 1 0.31 0.65 0.16 5.00
147 INT331600 Il18 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
148 INT331601 Il10 Regulation of IFN1@ 1 0.00 1.05 0.16 5.00
149 INT311227 INS Negative_regulation of HBA1 1 0.01 0.52 0.16 5.00
150 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16 5.00
151 INT303659 SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16 5.00
152 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
153 INT303657 Gene_expression of SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16 5.00
154 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
155 INT125770 GLP1R Negative_regulation of Localization of GCG 2 0.29 0.65 0.16 5.00
156 INT116124 Binding of AFP and HCC 2 0.20 1.72 0.15 5.00
157 INT329850 APOA5 Negative_regulation of Transcription of APOC3 1 0.24 0.85 0.15 5.00
158 INT278614 NR1I2 Regulation of Gene_expression of SULT2A1 1 0.11 0.11 0.15 5.00
159 INT334590 IRF6 Positive_regulation of Localization of Ptger2 1 0.00 0 0.15 5.00
160 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 5.00
161 INT217667 LEP Negative_regulation of Localization of INS 1 0.15 1.18 0.14 5.00
162 INT232018 Binding of SERPING1 and KNG1 1 0.15 0.81 0.14 5.00
163 INT217664 LEP Negative_regulation of INS 1 0.15 1.18 0.14 5.00
164 INT214480 SELPLG Negative_regulation of Positive_regulation of NFKB1 1 0.00 0.6 0.14 5.00
165 INT329847 PPARA Regulation of Gene_expression of CREB3L3 1 0.17 0.84 0.13 5.00
166 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13 5.00
167 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 5.00
168 INT252785 ELANE Regulation of Gene_expression of FBRS 1 0.00 0.5 0.13 5.00
169 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
170 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13 5.00
171 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12 5.00
172 INT232015 SERPING1 Negative_regulation of F12 2 0.24 1.19 0.12 5.00
173 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
174 INT278607 SULT2A1 Positive_regulation of Binding of PPARA 1 0.24 0 0.11 5.00
175 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11 5.00
176 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11 5.00
177 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11 5.00
178 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11 5.00
179 INT232017 F12 Positive_regulation of PLG 1 0.03 0.52 0.11 5.00
180 INT294451 KLK4 Negative_regulation of IL8 1 0.01 0 0.1 5.00
181 INT294449 KLK4 Negative_regulation of MMP9 1 0.01 0 0.1 5.00
182 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1 5.00
183 INT294440 KLK4 Negative_regulation of LIF 1 0.00 0 0.1 5.00
184 INT294456 KLK4 Negative_regulation of SERPINB2 1 0.01 0 0.1 5.00
185 INT294446 KLK4 Negative_regulation of HAS2 1 0.01 0 0.1 5.00
186 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
187 INT294454 KLK4 Negative_regulation of PTGS2 1 0.01 0 0.1 5.00
188 INT294441 KLK4 Negative_regulation of CXCR4 1 0.01 0 0.1 5.00
189 INT294452 KLK4 Negative_regulation of CCL4 1 0.00 0 0.1 5.00
190 INT294438 KLK4 Negative_regulation of IL1A 1 0.00 0 0.1 5.00
191 INT294437 KLK4 Negative_regulation of CXCL1 1 0.00 0 0.1 5.00
192 INT294453 KLK4 Negative_regulation of CCL2 1 0.00 0 0.1 5.00
193 INT294442 KLK4 Negative_regulation of IL6 1 0.00 0 0.1 5.00
194 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1 5.00
195 INT294450 KLK4 Negative_regulation of SERPINE1 1 0.01 0 0.1 5.00
196 INT294457 KLK4 Negative_regulation of MMP2 1 0.01 0 0.1 5.00
197 INT294448 KLK4 Negative_regulation of CTGF 1 0.01 0 0.1 5.00
198 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1 5.00
199 INT252790 Binding of NOS1 and NOS3 1 0.03 0.37 0.1 5.00
200 INT294443 KLK4 Negative_regulation of CXCL5 1 0.00 0 0.1 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gallstones. They are ordered first by their pain relevance and then by number of times they were reported in Gallstones. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT18773 Localization of ALB 117 0.80 69.18 13.8 100.00
2 INT283514 Localization of NR1I2 2 0.74 3.15 0.87 100.00
3 INT2421 Positive_regulation of Positive_regulation of Penk 97 0.69 13.38 55.32 100.00
4 INT15027 Positive_regulation of Localization of NA 11 0.26 3.4 2.98 100.00
5 INT35636 Gene_expression of Sord 6 0.78 2.31 1.35 100.00
6 INT283502 Positive_regulation of Gene_expression of ABCB4 1 0.40 0.76 0.62 99.98
7 INT14185 Regulation of CPB1 9 0.35 5.88 0.93 99.92
8 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.90
9 INT7979 Binding of Nsdhl 6 0.30 3.71 0.4 99.90
10 INT22906 Positive_regulation of Ggt1 3 0.45 5.42 0.92 99.88
11 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 99.88
12 INT283494 Positive_regulation of ABCB11 1 0.13 0.81 0.87 99.86
13 INT120529 Positive_regulation of ABCC2 7 0.49 2.32 2.94 99.86
14 INT287 Localization of Cck 518 0.81 86.84 364.04 99.84
15 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 99.84
16 INT30238 Positive_regulation of Anpep 14 0.66 2.77 3.38 99.84
17 INT2862 Positive_regulation of Localization of Cck 108 0.70 20.75 94.25 99.84
18 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53 99.84
19 INT12190 Negative_regulation of Localization of Got1 2 0.21 0.98 0.8 99.84
20 INT3919 Localization of Got1 10 0.71 2.95 3.28 99.84
21 INT14026 Positive_regulation of Igh-6 24 0.68 10.84 4.32 99.84
22 INT14880 Positive_regulation of Car3 14 0.65 9.19 3.73 99.80
23 INT130582 Gene_expression of ABCB4 3 0.67 1.05 0.82 99.78
24 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 99.76
25 INT27660 Binding of CFP 21 0.40 12.47 3.51 99.76
26 INT171253 Positive_regulation of BMI1 23 0.53 39.41 11.23 99.74
27 INT277009 Positive_regulation of PEX5 1 0.45 1.05 0.16 99.74
28 INT107011 Positive_regulation of NR1I2 14 0.49 8.85 3.11 99.74
29 INT9123 Regulation of Hal 3 0.61 0.5 0.56 99.72
30 INT19626 Regulation of Xdh 4 0.22 2.69 1.7 99.72
31 INT19628 Regulation of Xdh 6 0.45 1.9 1.07 99.72
32 INT22907 Positive_regulation of Ggt1 33 0.67 17.82 5.28 99.70
33 INT210020 Localization of Abcb4 3 0.71 1.65 0.34 99.70
34 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.70
35 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 99.70
36 INT230 Positive_regulation of GGTLC1 14 0.68 11.78 1.55 99.70
37 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 99.68
38 INT15026 Negative_regulation of Localization of NA 26 0.36 3.76 10.69 99.68
39 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.68
40 INT8765 Positive_regulation of Cyp3a23/3a1 63 0.67 22.28 20.39 99.66
41 INT626 Localization of CALCA 289 0.81 125.39 221.15 99.60
42 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.60
43 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51 99.60
44 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06 99.54
45 INT1154 Negative_regulation of CCK 24 0.59 9.3 15.32 99.54
46 INT2883 Negative_regulation of Localization of CCK 9 0.59 3.25 3.08 99.54
47 INT193334 Gene_expression of HPYR1 11 0.53 10.36 0.88 99.52
48 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 99.52
49 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.48
50 INT210021 Binding of Abcb4 1 0.37 2.47 0 99.48
51 INT49802 Localization of MUC1 75 0.81 44.74 8.87 99.48
52 INT49804 Negative_regulation of Localization of MUC1 7 0.59 5.84 1.19 99.48
53 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1 99.48
54 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 99.44
55 INT120286 Positive_regulation of Abcc2 11 0.70 4.71 6.2 99.44
56 INT282679 Localization of FECH 1 0.12 9.57 0.23 99.44
57 INT1898 Regulation of Crh 220 0.62 61.33 102.64 99.40
58 INT37005 Regulation of Nbr1 6 0.24 6.33 1.56 99.40
59 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89 99.36
60 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.32
61 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.28
62 INT397 Localization of SST 232 0.81 58.05 101.19 99.28
63 INT2085 Positive_regulation of LH 441 0.70 60.15 191.02 99.20
64 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 99.20
65 INT57122 Positive_regulation of Localization of AP1B1 3 0.16 0.39 1.93 99.20
66 INT2480 Negative_regulation of Got1 43 0.51 14.47 16.09 99.20
67 INT108173 Gene_expression of Abcb1b 14 0.75 8.61 4.26 99.18
68 INT5194 Positive_regulation of Lpo 63 0.70 26.44 8.37 99.14
69 INT176202 Gene_expression of Abcb4 6 0.68 5.25 0.52 99.12
70 INT136934 Negative_regulation of Urb1 6 0.36 2.53 2.38 99.12
71 INT152970 Positive_regulation of Negative_regulation of Urb1 1 0.18 0.49 0.62 99.12
72 INT11735 Positive_regulation of HBN1 15 0.29 5.69 0.17 99.04
73 INT2463 Localization of CCK 101 0.81 37.54 47.59 99.02
74 INT64180 Binding of Apoc4 2 0.33 3.03 0.23 99.00
75 INT5743 Localization of NA 104 0.59 14.35 35.29 99.00
76 INT4535 Localization of PROC 106 0.73 76.24 21.1 98.96
77 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 98.92
78 INT29821 Gene_expression of Serpina1 18 0.60 2.98 5.75 98.90
79 INT78659 Gene_expression of Thim 17 0.28 14.34 4.4 98.88
80 INT90300 Gene_expression of Abcb1a 56 0.78 11.05 22.89 98.88
81 INT322765 Negative_regulation of ABCB11 2 0.12 1.21 0.24 98.88
82 INT15000 Transcription of Oprd1 32 0.72 5.7 29.22 98.86
83 INT9126 Negative_regulation of Xdh 20 0.58 8.58 3.28 98.84
84 INT21721 Gene_expression of Lpo 25 0.60 16.33 2.57 98.80
85 INT4421 Positive_regulation of LAP 12 0.44 11.06 1.74 98.80
86 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 98.68
87 INT34884 Positive_regulation of Ugt1a2 8 0.24 5.23 1.73 98.68
88 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 98.68
89 INT20052 Negative_regulation of UGT1A1 12 0.58 4.51 4.29 98.56
90 INT1396 Binding of Penk 355 0.48 22.79 269.65 98.52
91 INT19986 Negative_regulation of Cck 31 0.59 4.32 24.99 98.52
92 INT253811 Negative_regulation of Localization of Cck 2 0.41 0.76 0.86 98.52
93 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 98.50
94 INT18778 Gene_expression of Ugt1a2 17 0.35 9.91 6.87 98.50
95 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 98.48
96 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 98.42
97 INT73340 Negative_regulation of Faah 134 0.59 38.67 85.03 98.40
98 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 98.36
99 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 98.34
100 INT36623 Positive_regulation of RSPH1 2 0.40 0.69 0.1 98.32
101 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 98.32
102 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 98.30
103 INT158 Localization of Prl 2431 0.81 378.96 952.2 98.28
104 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 98.28
105 INT227413 Gene_expression of DLAT 12 0.44 13.21 1.36 98.24
106 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.22
107 INT7832 Localization of Cck 39 0.81 6.81 26.54 98.16
108 INT14883 Regulation of Car3 8 0.58 5.57 2.75 98.16
109 INT3703 Negative_regulation of Grhpr 38 0.50 11.43 9.2 98.08
110 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 98.08
111 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 98.08
112 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 98.06
113 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 98.04
114 INT83837 Gene_expression of CEACAM6 7 0.76 13.8 4.59 98.04
115 INT84809 Positive_regulation of Gene_expression of MUC1 39 0.70 36.42 3.75 98.04
116 INT156485 Positive_regulation of Gene_expression of CEACAM6 3 0.49 6.5 1.54 98.04
117 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 98.04
118 INT85830 Positive_regulation of Gene_expression of CA9 4 0.41 5.47 1.02 98.04
119 INT340339 Negative_regulation of UGT1A 1 0.42 1.56 0.21 98.00
120 INT35143 Negative_regulation of ANGPTL5 28 0.54 18.59 3.14 98.00
121 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 97.96
122 INT170470 Binding of CD14 27 0.35 14.89 5.16 97.94
123 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 97.92
124 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7 97.84
125 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 97.72
126 INT57123 Localization of AP1B1 5 0.24 1.29 2.91 97.68
127 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 97.64
128 INT10671 Regulation of CRX 4 0.53 6.29 1.78 97.64
129 INT104182 Gene_expression of ABCC2 19 0.76 5.92 2.88 97.64
130 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 97.64
131 INT27585 Positive_regulation of smc 9 0.58 3.2 1.47 97.60
132 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 97.60
133 INT147873 Negative_regulation of Gene_expression of GRIN1 8 0.58 2.3 1.46 97.60
134 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 97.56
135 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 97.54
136 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 97.46
137 INT35329 Positive_regulation of KRTAP19-9P 15 0.59 12.55 2.98 97.44
138 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 97.32
139 INT229326 Negative_regulation of CYP7A1 3 0.29 1.03 0.7 97.30
140 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 97.28
141 INT99410 Positive_regulation of UGT1A1 10 0.45 2.2 2.07 97.28
142 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 97.24
143 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 97.20
144 INT132278 Binding of CTLA4 32 0.39 18.69 8.17 97.12
145 INT283500 Positive_regulation of Gene_expression of ABCB11 1 0.08 0.41 0.48 97.08
146 INT283495 Gene_expression of ABCB11 1 0.10 0.41 0.47 97.08
147 INT120288 Regulation of Gene_expression of Abcc2 5 0.44 1.3 1.52 96.92
148 INT162521 Regulation of Gene_expression of Ugt2b1 1 0.54 0.19 0.66 96.92
149 INT134504 Regulation of Gene_expression of Abcc3 4 0.57 0.47 2.39 96.92
150 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 96.80
151 INT3948 Regulation of Cck 291 0.62 58.07 255.88 96.80
152 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 96.78
153 INT19966 Positive_regulation of C9orf3 19 0.67 21.88 4.38 96.76
154 INT19545 Positive_regulation of IV 5 0.61 4.22 0.83 96.76
155 INT38543 Positive_regulation of Positive_regulation of IV 1 0.44 1.18 0.16 96.76
156 INT309847 Binding of Frl 1 0.02 0.83 0 96.72
157 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 96.64
158 INT169174 Gene_expression of H19h 1 0.00 0.85 0.14 96.64
159 INT274704 Localization of GPT 5 0.73 3.91 0.29 96.60
160 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23 96.56
161 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 96.52
162 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 96.52
163 INT12159 Transcription of Cck 46 0.72 9.36 37.58 96.50
164 INT52170 Regulation of Cckbr 5 0.58 1.34 3.69 96.44
165 INT283496 Localization of CASR 2 0.76 2.04 0.41 96.32
166 INT6852 Localization of TNF 883 0.81 705.95 270.84 96.28
167 INT293 Protein_catabolism of Penk 161 1.00 11.71 98.45 96.24
168 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 96.22
169 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 96.08
170 INT58625 Gene_expression of Ugt2b1 19 0.77 1.95 7.05 96.08
171 INT169178 Gene_expression of Abcg8 1 0.35 0.84 0.14 96.04
172 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 96.02
173 INT546 Binding of ALB 311 0.48 85.98 60.14 95.96
174 INT213613 Localization of NPS 2 0.62 1.11 0.23 95.88
175 INT278659 Transcription of SULT2A1 1 0.40 0.25 0.21 95.88
176 INT176212 Transcription of Nr1h2 5 0.29 2.92 0.15 95.88
177 INT110515 Regulation of Negative_regulation of Faah 5 0.43 2.84 5.2 95.72
178 INT110208 Binding of ABR 2 0.35 10.49 0.81 95.72
179 INT4015 Positive_regulation of SCTR 5 0.37 6.45 1.62 95.68
180 INT4014 Positive_regulation of Positive_regulation of SCTR 1 0.37 0.82 0.42 95.68
181 INT104499 Gene_expression of Abcc3 16 0.78 1.67 9.34 95.64
182 INT57125 Gene_expression of AP1B1 8 0.18 3.8 4.91 95.64
183 INT4553 Binding of G6PD 7 0.37 3 0.44 95.60
184 INT1530 Regulation of Gh 382 0.61 115.96 112.47 95.56
185 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 95.56
186 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 95.52
187 INT104502 Gene_expression of Abcc2 26 0.78 8.37 9.65 95.40
188 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 95.40
189 INT275878 Positive_regulation of Gene_expression of Aes 4 0.23 4.54 3.39 95.40
190 INT210022 Localization of Thim 1 0.01 1.02 0.14 95.36
191 INT15362 Negative_regulation of Cela1 4 0.21 2.47 0.83 95.28
192 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 95.24
193 INT135029 Positive_regulation of Gene_expression of Cd14 11 0.66 6.4 1.75 95.24
194 INT233975 Positive_regulation of Gene_expression of Myd88 7 0.66 4.17 1.65 95.24
195 INT57431 Binding of PIAS1 4 0.30 4.35 1.94 95.20
196 INT1893 Localization of Gh 1041 0.79 340.23 256.58 95.12
197 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 95.08
198 INT2139 Negative_regulation of Cea 55 0.43 43.59 9.14 94.88
199 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 94.84
200 INT140436 Binding of TWIST1 5 0.39 2.34 0.47 94.84
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