D:Gangliosidoses

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Ganglioside Storage Disease, Ganglioside Storage Diseases, GANGLIOSIDE STORAGE DISORDER, Ganglioside Storage Disorders, Gangliosidosis, STORAGE DISEASE GANGLIOSIDE, STORAGE DISEASES GANGLIOSIDE, Storage Disorder Ganglioside, Storage Disorders Ganglioside
Documents 14
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gangliosidoses. They are ordered first by their relevance to Gangliosidoses and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT347806 Binding of MOCS1 and SMAP2 1 0.00 0.48 0.12 60.08
2 INT347807 GLA Positive_regulation of Positive_regulation of A4GALT 1 0.05 1.57 0.13 5.00
3 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
4 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gangliosidoses. They are ordered first by their pain relevance and then by number of times they were reported in Gangliosidoses. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 100.00
2 INT87332 Gene_expression of Cyb5d2 8 0.65 2.85 0.15 100.00
3 INT62843 Negative_regulation of Binding of HEXA 1 0.41 0.82 0.09 99.92
4 INT62844 Binding of HEXA 2 0.36 1.45 0.23 99.92
5 INT42410 Positive_regulation of Cyb5d2 13 0.31 6.75 0.54 99.58
6 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 97.88
7 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 97.88
8 INT154840 Negative_regulation of HHEX 1 0.42 0.45 0.17 97.20
9 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 92.04
10 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 91.56
11 INT171117 Binding of Itgam 35 0.36 14.87 2.76 88.76
12 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 88.44
13 INT3798 Negative_regulation of GNS 5 0.26 3.18 2.21 87.24
14 INT233970 Regulation of Myd88 7 0.45 5.2 1.28 82.80
15 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 82.76
16 INT43906 Regulation of Tlr4 71 0.53 35.18 15.49 82.00
17 INT97453 Negative_regulation of MOCS1 25 0.04 13.4 2.4 76.56
18 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12 75.20
19 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 75.00
20 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 75.00
21 INT48728 Negative_regulation of IGFBP3 28 0.59 14.84 1.21 75.00
22 INT61065 Positive_regulation of Igfbp2 9 0.69 1.13 0.3 75.00
23 INT85168 Negative_regulation of Om 5 0.02 0.32 0.72 75.00
24 INT57820 Positive_regulation of Om 12 0.12 3.19 3.56 75.00
25 INT97861 Negative_regulation of Gene_expression of CTSA 3 0.13 1.11 0.09 74.80
26 INT97860 Gene_expression of CTSA 8 0.43 2.22 0.54 74.36
27 INT97859 Localization of Npc1 12 0.75 6.66 0.35 71.52
28 INT94175 Negative_regulation of GALNT3 2 0.06 2.87 0.82 63.24
29 INT94174 Negative_regulation of B3GALNT1 1 0.20 1.1 0.11 63.24
30 INT94176 Negative_regulation of NEU1 1 0.11 1.09 0.11 63.24
31 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 61.68
32 INT17886 Negative_regulation of Il1 95 0.57 70.91 31.25 61.68
33 INT25076 Negative_regulation of Gene_expression of Il1 41 0.52 30.58 13.85 61.68
34 INT233974 Negative_regulation of Negative_regulation of Il1 2 0.30 1.47 1.07 61.68
35 INT61252 Negative_regulation of Gene_expression of Itgam 38 0.54 16.48 5.01 61.12
36 INT79941 Negative_regulation of Npc1 9 0.59 3.97 0.82 60.56
37 INT347808 Binding of SMAP2 1 0.00 0.47 0.12 58.72
38 INT94173 Positive_regulation of CTSA 3 0.53 3.22 0.4 55.84
39 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 48.80
40 INT15173 Positive_regulation of Gene_expression of Itgam 59 0.49 21.89 5.43 48.80
41 INT94177 Positive_regulation of Positive_regulation of CTSA 1 0.38 0.76 0.06 45.60
42 INT197491 Gene_expression of Myd88 32 0.74 14.59 5.29 43.68
43 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 42.88
44 INT198787 Localization of Cyb5d2 3 0.73 0.56 0.03 36.64
45 INT310677 Localization of ARSB 1 0.71 5.72 0.14 33.28
46 INT142752 Positive_regulation of Myd88 26 0.66 12.07 4.4 33.12
47 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 32.32
48 INT59321 Transcription of Il1 13 0.50 9.73 2.68 29.44
49 INT152888 Transcription of Itgam 4 0.44 1.29 0.25 29.44
50 INT142724 Negative_regulation of A4GALT 11 0.53 8.23 2.61 21.28
51 INT16723 Regulation of GBE1 16 0.11 4.3 3.7 9.40
52 INT71946 Negative_regulation of Ass1 7 0.41 1.9 2.68 5.60
53 INT55529 Negative_regulation of Gba 13 0.59 7.91 2.1 5.20
54 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
55 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 5.00
56 INT81289 Positive_regulation of Gene_expression of Tlr4 192 0.69 104.5 33.89 5.00
57 INT56809 Binding of Tlr4 184 0.48 106.02 31.18 5.00
58 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
59 INT73354 Gene_expression of Gap43 36 0.77 13.74 7.47 5.00
60 INT112459 Localization of Gba 12 0.80 1.45 6.4 5.00
61 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 5.00
62 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 5.00
63 INT103760 Regulation of Gene_expression of Tlr4 35 0.59 16.26 5.95 5.00
64 INT49632 Negative_regulation of NBL1 11 0.57 1.11 5.67 5.00
65 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 5.00
66 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
67 INT97254 Positive_regulation of Gap43 22 0.46 7.36 4.48 5.00
68 INT142754 Binding of Myd88 20 0.36 9.61 3.8 5.00
69 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
70 INT134944 Gene_expression of MOCS1 37 0.06 10.76 2.17 5.00
71 INT89981 Regulation of Gene_expression of Gap43 2 0.55 3.1 2.13 5.00
72 INT68829 Binding of ELF3 14 0.47 7.96 2 5.00
73 INT167153 Gene_expression of A4GALT 10 0.49 10.45 1.71 5.00
74 INT233975 Positive_regulation of Gene_expression of Myd88 7 0.66 4.17 1.65 5.00
75 INT121513 Positive_regulation of A4GALT 21 0.63 16.06 1.59 5.00
76 INT131125 Negative_regulation of Localization of Gba 2 0.08 0.24 1.48 5.00
77 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24 5.00
78 INT287436 Positive_regulation of HTs 9 0.60 2.27 1.14 5.00
79 INT36179 Regulation of GLA 11 0.44 6.56 1.12 5.00
80 INT209387 Negative_regulation of Ugcg 9 0.25 7.61 0.9 5.00
81 INT57560 Positive_regulation of GLA 14 0.54 5.01 0.83 5.00
82 INT139160 Negative_regulation of Gap43 5 0.43 1.27 0.77 5.00
83 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 5.00
84 INT164258 Positive_regulation of Gene_expression of GLA 6 0.47 0.55 0.65 5.00
85 INT233973 Negative_regulation of Gene_expression of Myd88 4 0.38 1.32 0.61 5.00
86 INT142723 Negative_regulation of Positive_regulation of A4GALT 4 0.38 1.65 0.34 5.00
87 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 5.00
88 INT197492 Regulation of Gene_expression of Myd88 2 0.39 1.95 0.27 5.00
89 INT320171 Positive_regulation of Gene_expression of MOCS1 2 0.01 0.87 0.25 5.00
90 INT47550 Gene_expression of Naglu 4 0.44 2.02 0.23 5.00
91 INT173211 Regulation of MOCS1 4 0.01 1.94 0.22 5.00
92 INT117050 Binding of GLA 8 0.47 2.41 0.22 5.00
93 INT233971 Transcription of Myd88 2 0.60 1.01 0.17 5.00
94 INT277778 Regulation of AFD1 1 0.01 0.88 0.13 5.00
95 INT229456 Negative_regulation of Gene_expression of Gap43 3 0.11 0.41 0.09 5.00
96 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04 5.00
97 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04 5.00
98 INT310682 Regulation of ARSB 1 0.43 0.98 0.04 5.00
99 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04 5.00
100 INT210071 Positive_regulation of Transcription of GLA 2 0.54 0.67 0.03 5.00
101 INT210062 Transcription of GLA 2 0.56 0.67 0.03 5.00
102 INT307030 Localization of LAMP1 4 0.42 0.57 0.03 5.00
103 INT233972 Regulation of Gene_expression of Cyb5d2 1 0.16 0.17 0.03 5.00
104 INT347809 Negative_regulation of Binding of A4GALT 1 0.05 0 0 5.00
105 INT347810 Binding of A4GALT 1 0.04 0 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox