D:Gastric Motility Disorder

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Disease Term
Synonyms CYCLIC VOMITING SYNDROME, Delayed Gastric Emptying, Delayed Gastrointestinal Transit, Diffuse Gastrointestinal Dysmotility, DUODENOGASTRIC REFLUX, Esophageal Motility Impairment, Gastric Dysrhythmia, Gastric Motility Disorders, Gastro Esophageal Reflux Disease, GASTRO OESOPHAGEAL REFLUX DISEASE, GASTROINTESTINAL DYSMOTILITY
Documents 675
Hot Single Events 148
Hot Interactions 7

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gastric Motility Disorder. They are ordered first by their relevance to Gastric Motility Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33 100.00
2 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 97.32
3 INT343027 Binding of CYP3A4 and Azi1 1 0.02 0.75 0.14 94.48
4 INT157080 Ghrl Positive_regulation of Localization of Gnrhr 2 0.23 0.7 0.26 93.76
5 INT203018 GHRH Positive_regulation of Localization of PYY 1 0.01 0.81 0.12 90.32
6 INT227325 Binding of IRF6 and Cd14 1 0.01 2.51 0.93 87.32
7 INT118136 Binding of HTR1A and HTR2A 1 0.36 0.77 0.45 83.28
8 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 79.20
9 INT325421 PHF20 Positive_regulation of Localization of Gnrhr 1 0.00 0.39 0.17 72.36
10 INT314624 Ex Regulation of GCG 1 0.01 0.67 0 65.88
11 INT314621 Ex Regulation of INS 1 0.06 0.67 0 65.88
12 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17 64.44
13 INT203015 CCK Regulation of Localization of PYY 1 0.24 0.61 0.28 64.44
14 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78 61.72
15 INT227324 Binding of fd and Cd14 1 0.01 2.8 1.13 53.84
16 INT321466 Glp1r Regulation of DPP4 1 0.04 0.59 0.06 40.92
17 INT321465 Gip Regulation of DPP4 1 0.03 0.59 0.06 40.52
18 INT314620 Ex Positive_regulation of GLP1R Positive_regulation of Gene_expression of INS 1 0.03 0.3 0.11 40.48
19 INT203017 Binding of CCK and PYY 1 0.38 0.62 0.43 39.64
20 INT314625 Ex Positive_regulation of GLP1R 1 0.03 0.3 0.11 37.92
21 INT191984 Ide Positive_regulation of Nppc 1 0.04 0.13 0 32.24
22 INT126335 Binding of Pax3 and Tac1 6 0.07 6.22 5.27 5.00
23 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
24 INT115656 Glp1r Positive_regulation of Localization of Ins1 2 0.42 5.23 0.91 5.00
25 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
26 INT287132 Binding of NT5E and Comt 1 0.03 0.11 0.73 5.00
27 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71 5.00
28 INT261517 Binding of HTR2A and USH1C 1 0.01 0 0.66 5.00
29 INT351076 IK Positive_regulation of Gene_expression of Ucp3 1 0.00 0.8 0.58 5.00
30 INT187222 Binding of Vip and Vipr2 2 0.19 1.82 0.56 5.00
31 INT265359 Efs Positive_regulation of Car2 1 0.19 0.42 0.45 5.00
32 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 5.00
33 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 5.00
34 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 5.00
35 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 5.00
36 INT287131 Negative_regulation of Binding of NT5E and Comt 1 0.03 0.06 0.23 5.00
37 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
38 INT265360 Binding of Car2 and Daf2 1 0.18 0.09 0.22 5.00
39 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
40 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 5.00
41 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18 5.00
42 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 5.00
43 INT261518 Binding of DLG4 and HTR4 1 0.01 0 0.16 5.00
44 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
45 INT261521 Binding of ADCY1 and GLUL 1 0.01 0.09 0.15 5.00
46 INT261520 Binding of DLG4 and HTR2A 1 0.06 0 0.14 5.00
47 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 5.00
48 INT261519 Binding of HTR4 and USH1C 1 0.00 0 0.13 5.00
49 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
50 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 5.00
51 INT287130 Positive_regulation of Binding of NT5E and Comt 1 0.04 0 0.12 5.00
52 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
53 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
54 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
55 INT332637 Negative_regulation of Dpp4 Negative_regulation of Localization of Ins1 1 0.06 1.66 0.1 5.00
56 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1 5.00
57 INT328297 GHRH Positive_regulation of Transcription of GH1 1 0.04 0.26 0.1 5.00
58 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1 5.00
59 INT280053 Negative_regulation of Dpp4 Negative_regulation of Protein_catabolism of Zglp1 1 0.02 0.71 0.1 5.00
60 INT328311 Binding of GH1 and GHS 1 0.02 0.14 0.09 5.00
61 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 5.00
62 INT325418 Ghrl Positive_regulation of Ghsr 1 0.16 0 0.08 5.00
63 INT328302 Gene_expression of GHS Positive_regulation of Gene_expression of GH1 1 0.03 0.17 0.08 5.00
64 INT196337 Binding of CDSN and HBM 1 0.00 0.79 0.08 5.00
65 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 5.00
66 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07 5.00
67 INT332639 Glp1r Negative_regulation of Localization of Gcg 1 0.03 0.87 0.07 5.00
68 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 5.00
69 INT261556 Binding of USH1C and Olr1746 1 0.01 0 0.06 5.00
70 INT224922 Binding of FAP and TARM1 1 0.06 1.4 0.06 5.00
71 INT267923 Negative_regulation of Dpp4 Positive_regulation of Glp1r 1 0.00 0.23 0.05 5.00
72 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 5.00
73 INT332641 Binding of PPARG and Ins1 1 0.12 1.05 0.05 5.00
74 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05 5.00
75 INT321467 Binding of DPP4 and Glp1r 1 0.03 0.42 0.05 5.00
76 INT332631 Negative_regulation of Dpp4 Negative_regulation of Gcg 1 0.05 1 0.05 5.00
77 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05 5.00
78 INT298734 USE1 Regulation of ACSBG1 1 0.00 0.97 0.05 5.00
79 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 5.00
80 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 5.00
81 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05 5.00
82 INT254161 Epo Positive_regulation of Nos2 1 0.37 0.54 0.05 5.00
83 INT328367 KISS1 Positive_regulation of Localization of Gnrh1 1 0.00 0 0.05 5.00
84 INT332628 Negative_regulation of Dpp4 Negative_regulation of Positive_regulation of Gcg 1 0.05 1 0.05 5.00
85 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05 5.00
86 INT328292 KISS1 Positive_regulation of Localization of PLOD1 1 0.00 0 0.05 5.00
87 INT280057 Zglp1 Positive_regulation of Transcription of INS 1 0.04 0.52 0.05 5.00
88 INT328293 Binding of JAG2 and GHS 1 0.03 0.09 0.05 5.00
89 INT254162 Epo Positive_regulation of NOS1 1 0.01 0.53 0.05 5.00
90 INT332638 Gip Regulation of Glp1r 1 0.02 0.47 0.05 5.00
91 INT297121 Binding of GNB3 and Eps8l3 1 0.00 0.81 0.05 5.00
92 INT332633 Glp1r Negative_regulation of Gcg 1 0.04 1.13 0.05 5.00
93 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05 5.00
94 INT332632 Gip Negative_regulation of Localization of Gcg 1 0.05 0.47 0.04 5.00
95 INT326625 Binding of ALB and Trf 1 0.01 0.64 0.04 5.00
96 INT314622 Binding of INS and Ex 1 0.08 0.44 0.04 5.00
97 INT181168 Binding of CD79A and TAPBP 1 0.10 0.7 0.04 5.00
98 INT227333 Il2 Positive_regulation of Hmox1 1 0.05 0.93 0.04 5.00
99 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 5.00
100 INT332635 Glp1r Regulation of Localization of Gcg 1 0.03 0.94 0.04 5.00
101 INT328301 GHRH Positive_regulation of SCG5 1 0.24 0.13 0.04 5.00
102 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04 5.00
103 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 5.00
104 INT191980 Ide Regulation of Sit1 1 0.17 0 0.04 5.00
105 INT328295 GHRH Positive_regulation of GHS 1 0.10 0.13 0.04 5.00
106 INT195195 IL4 Regulation of Gene_expression of IGHE 1 0.10 0.68 0.04 5.00
107 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04 5.00
108 INT332640 Glp1r Regulation of Localization of Ins1 1 0.04 0.52 0.04 5.00
109 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03 5.00
110 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03 5.00
111 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 5.00
112 INT314771 Glp1r Positive_regulation of Gene_expression of Ins1 2 0.04 1.23 0.03 5.00
113 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03 5.00
114 INT195199 Gene_expression of IL4 Positive_regulation of Gene_expression of IGHE 1 0.08 1.76 0 5.00
115 INT351466 NMD3 Positive_regulation of Protein_catabolism of UPF1 1 0.00 0.54 0 5.00
116 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
117 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 5.00
118 INT332629 Binding of Glp1r and Positive_regulation of Localization of Gcg 1 0.03 0.47 0 5.00
119 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 5.00
120 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0 5.00
121 INT181167 TAPBP Negative_regulation of CD79A 1 0.11 0.48 0 5.00
122 INT195198 Gene_expression of IL5 Positive_regulation of Gene_expression of IGHE 1 0.09 1.76 0 5.00
123 INT224921 Binding of TTR and TARM1 1 0.06 1.06 0 5.00
124 INT332636 Binding of Glp1r and Positive_regulation of Localization of Ins1 1 0.03 0.47 0 5.00
125 INT191982 Sit1 Regulation of Gene_expression of Ide 1 0.25 0.09 0 5.00
126 INT332634 Dpp4 Positive_regulation of Localization of Ins1 1 0.06 0.76 0 5.00
127 INT195197 Gene_expression of IL9 Positive_regulation of Gene_expression of IGHE 1 0.05 1.77 0 5.00
128 INT195196 IL13 Positive_regulation of Gene_expression of IGHE 1 0.06 1.79 0 5.00
129 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 5.00
130 INT191981 Ide Positive_regulation of Positive_regulation of Sit1 1 0.28 0.06 0 5.00
131 INT256400 GLP1R Positive_regulation of Localization of GCG 1 0.02 0.15 0 5.00
132 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0 5.00
133 INT314623 Ex Positive_regulation of INS 1 0.10 1.46 0 5.00
134 INT181165 TAPBP Regulation of Gene_expression of CD79A 1 0.07 0.35 0 5.00
135 INT290861 MNT Positive_regulation of INS 1 0.03 1.78 0 5.00
136 INT351465 PRSS1 Regulation of Gene_expression of IKBKAP 1 0.00 0.65 0 5.00
137 INT312950 Binding of ADA and HBN1 1 0.01 0.49 0 5.00
138 INT332627 Positive_regulation of Ins1 Positive_regulation of Phosphorylation of Hk2 1 0.01 0.83 0 5.00
139 INT293950 Binding of CTNND2 and Spn 1 0.06 1.69 0 5.00
140 INT195200 IL10 Positive_regulation of Gene_expression of IGHE 1 0.07 1.78 0 5.00
141 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0 5.00
142 INT196338 Binding of CDSN and HRASLS 1 0.00 0.64 0 5.00
143 INT325420 Ghrl Regulation of Mag 1 0.02 0 0 5.00
144 INT273197 Binding of BCR and COPD 1 0.03 0.4 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gastric Motility Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Gastric Motility Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT214581 Negative_regulation of GYPC 32 0.32 21.93 3.62 100.00
2 INT164926 Regulation of GYPC 9 0.46 16.66 2.04 100.00
3 INT214860 Binding of GYPC 10 0.36 11.18 0.74 100.00
4 INT218577 Gene_expression of GYPC 6 0.50 5.16 0.44 100.00
5 INT218578 Positive_regulation of GYPC 10 0.37 5.7 1.92 100.00
6 INT343017 Positive_regulation of Azi1 1 0.21 2.39 0.16 100.00
7 INT343019 Positive_regulation of Positive_regulation of Azi1 1 0.21 1.58 0.13 100.00
8 INT183755 Localization of GYPC 4 0.56 3.91 1.42 100.00
9 INT82901 Regulation of ge 2 0.00 1.02 0.25 100.00
10 INT16879 Binding of Crh 72 0.48 21.65 28.43 100.00
11 INT82902 Regulation of Negative_regulation of ge 1 0.00 0.63 0.18 100.00
12 INT79877 Negative_regulation of ge 4 0.34 2.01 0.76 100.00
13 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 100.00
14 INT218579 Regulation of Gene_expression of GYPC 1 0.33 1.3 0.08 100.00
15 INT1221 Regulation of SGCG 65 0.60 24.21 22.94 99.98
16 INT260164 Positive_regulation of Gene_expression of PPPD1 1 0.41 0.96 0 99.98
17 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 99.92
18 INT260162 Gene_expression of PPPD1 4 0.55 4.26 0.04 99.86
19 INT21841 Positive_regulation of PPPD1 4 0.38 3.46 0.16 99.84
20 INT138555 Negative_regulation of Tymp 3 0.39 3.31 0.74 99.84
21 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 99.84
22 INT138554 Positive_regulation of Negative_regulation of Tymp 1 0.13 0.7 0.28 99.84
23 INT17625 Localization of GCG 210 0.80 55.69 24.97 99.80
24 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 99.80
25 INT624 Positive_regulation of GAST 28 0.70 15.61 4.73 99.80
26 INT117117 Positive_regulation of REM1 12 0.40 10.1 3.33 99.78
27 INT19614 Binding of PPPD1 3 0.40 3.13 0.26 99.76
28 INT8740 Localization of Gcg 65 0.78 19 9.81 99.76
29 INT98773 Negative_regulation of Localization of Gcg 10 0.53 9.59 1.5 99.76
30 INT119195 Binding of Cotl1 11 0.14 6.77 2.21 99.68
31 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 99.32
32 INT116528 Gene_expression of HMOX1 106 0.78 86.13 12.8 99.16
33 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 99.12
34 INT3948 Regulation of Cck 291 0.62 58.07 255.88 99.08
35 INT24166 Localization of Mln 40 0.80 9.11 10.32 99.08
36 INT28 Regulation of Gast 106 0.62 26.37 29.85 99.08
37 INT9128 Regulation of Gene_expression of Cck 27 0.62 6.55 19.45 99.08
38 INT238448 Binding of Zglp1 4 0.24 2.07 0.93 99.00
39 INT203020 Positive_regulation of PYY 37 0.68 18.81 9.63 98.96
40 INT39919 Negative_regulation of MLN 9 0.36 2.91 1.06 98.78
41 INT18462 Positive_regulation of Pgc 29 0.57 22.55 3.24 98.72
42 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 98.54
43 INT30 Gene_expression of Gast 158 0.78 99 41.45 98.54
44 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 98.52
45 INT1114 Localization of Ins1 748 0.80 192.95 165.48 98.52
46 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 98.44
47 INT122896 Negative_regulation of TH 23 0.57 9.27 6.88 98.06
48 INT812 Localization of INS 1026 0.81 515.6 145.31 98.04
49 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 98.00
50 INT143400 Positive_regulation of ge 3 0.37 1.09 0.09 98.00
51 INT280032 Protein_catabolism of ge 1 0.04 0.91 0.09 97.96
52 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 97.96
53 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 97.92
54 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39 97.92
55 INT260161 Regulation of PPPD1 1 0.37 0.45 0 97.84
56 INT7827 Binding of Cck 32 0.48 4.66 23.73 97.84
57 INT75778 Regulation of GER 8 0.61 4.18 0.32 97.48
58 INT1473 Localization of Gcg 95 0.80 17.35 30.31 97.44
59 INT3658 Regulation of Gcg 28 0.53 12.89 8.58 97.44
60 INT351284 Regulation of Localization of AP1M2 1 0.04 0.85 1.9 97.32
61 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 97.04
62 INT72110 Gene_expression of Glp1r 48 0.78 22.46 6.17 96.96
63 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 96.92
64 INT203021 Positive_regulation of Localization of PYY 8 0.47 4.86 1.87 96.92
65 INT2366 Binding of Cck 192 0.48 30.64 163.46 96.68
66 INT233 Binding of Gast 31 0.42 17.07 5.21 96.68
67 INT351285 Localization of AP1M2 1 0.07 0.79 1.89 96.68
68 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 96.60
69 INT1898 Regulation of Crh 220 0.62 61.33 102.64 96.48
70 INT145114 Binding of Azi1 2 0.16 0.39 0.2 96.48
71 INT128369 Localization of PYY 27 0.79 10.39 7.06 96.40
72 INT2885 Positive_regulation of Localization of CCK 19 0.70 9.92 8.94 95.96
73 INT260163 Negative_regulation of PPPD1 1 0.35 0.73 0 95.88
74 INT18400 Localization of Glp1r 97 0.80 11.96 24.32 95.68
75 INT43259 Negative_regulation of FAIM3 7 0.43 2.7 3.41 95.68
76 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 95.60
77 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 95.60
78 INT2463 Localization of CCK 101 0.81 37.54 47.59 95.60
79 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 95.28
80 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 95.24
81 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 95.20
82 INT351509 Positive_regulation of IKBKAP 19 0.70 29.01 0.63 95.20
83 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 95.12
84 INT9012 Localization of Vip 283 0.81 31.71 106.16 95.12
85 INT17811 Positive_regulation of Localization of Vip 35 0.67 0.85 12.67 95.12
86 INT138556 Positive_regulation of TYMP 23 0.58 12.9 0.28 94.96
87 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 94.92
88 INT224924 Binding of TARM1 4 0.18 3.42 0.39 94.92
89 INT22389 Regulation of MLN 9 0.61 4.39 3.08 94.52
90 INT19009 Positive_regulation of Ghsr 17 0.64 5.71 2.78 94.36
91 INT8724 Positive_regulation of Mln 21 0.66 14.12 6.17 94.36
92 INT323979 Negative_regulation of Negative_regulation of Ghrl 2 0.42 0.98 0.76 94.36
93 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36 93.88
94 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5 93.76
95 INT3216 Positive_regulation of Localization of Ins1 170 0.69 56.78 35.63 93.28
96 INT127523 Negative_regulation of Negative_regulation of Ex 1 0.09 0.28 0.27 93.28
97 INT62848 Negative_regulation of GER 8 0.57 3.89 0.93 92.96
98 INT3214 Localization of Ins1 527 0.80 196.9 79.26 92.80
99 INT5617 Localization of Nppa 266 0.81 83.51 83.89 92.68
100 INT136074 Regulation of ELOVL1 5 0.23 3.6 0.49 92.64
101 INT145960 Positive_regulation of GLP1R 19 0.58 7.25 1.19 92.60
102 INT242210 Positive_regulation of Gene_expression of GLP1R 6 0.58 3.59 0.61 92.60
103 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 92.44
104 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 92.32
105 INT127525 Negative_regulation of Ex 3 0.10 1.62 0.31 92.28
106 INT2197 Gene_expression of Gnrh1 184 0.78 40.04 50.57 91.92
107 INT140929 Gene_expression of Cd40 9 0.72 8.76 2.88 91.92
108 INT242212 Gene_expression of GLP1R 29 0.65 11.36 1.52 91.92
109 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 91.84
110 INT3182 Negative_regulation of PPY 12 0.42 4.65 2.28 91.84
111 INT118207 Binding of Ghrl 11 0.47 7.39 3.52 90.96
112 INT18933 Binding of GER 11 0.37 11.56 0.3 90.24
113 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 90.00
114 INT251830 Binding of TYMP 2 0.13 4.36 0.37 89.76
115 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 88.84
116 INT84211 Positive_regulation of Cnrip1 7 0.69 1.4 3.83 88.84
117 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 88.20
118 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 88.00
119 INT139780 Binding of AQP1 7 0.32 4.62 0.54 87.92
120 INT251 Regulation of INS 398 0.62 232.47 55.04 86.80
121 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 86.72
122 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 86.56
123 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46 86.56
124 INT211375 Regulation of Gene_expression of TYMP 2 0.43 2.44 0.22 86.40
125 INT153346 Binding of Cd14 11 0.31 8.64 3.06 86.32
126 INT20283 Localization of RLN1 3 0.80 0.71 0.17 86.12
127 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 86.04
128 INT158444 Positive_regulation of Cnp 6 0.63 5 0.55 85.12
129 INT2407 Regulation of GAST 26 0.62 5.31 10.04 85.04
130 INT76403 Gene_expression of Cnp 16 0.70 8.36 3.07 84.64
131 INT69486 Negative_regulation of Bcl2a1c 34 0.10 19.03 0.6 84.48
132 INT116527 Positive_regulation of Gene_expression of HMOX1 29 0.70 25.79 4.87 84.12
133 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21 83.08
134 INT226478 Protein_catabolism of DPP4 11 0.85 5.52 0.95 82.72
135 INT133228 Protein_catabolism of Glp1r 8 0.88 2.65 0.48 82.72
136 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 82.72
137 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 82.52
138 INT55658 Binding of HTR4 8 0.47 2.14 2.19 82.32
139 INT17267 Regulation of Csprs 1 0.22 0.28 0.26 82.08
140 INT5118 Regulation of SST 97 0.62 34.35 51.74 81.52
141 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 81.52
142 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38 81.36
143 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 80.92
144 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 80.56
145 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 80.52
146 INT90 Localization of Gast 400 0.81 137.67 113 80.48
147 INT183362 Regulation of AQP1 3 0.23 1.49 0.92 80.32
148 INT91 Positive_regulation of Localization of Gast 96 0.70 23.22 29.36 80.16
149 INT1988 Positive_regulation of Localization of Ins1 254 0.69 59.25 68.37 80.00
150 INT28576 Binding of MLN 18 0.48 5.45 2.26 79.92
151 INT219847 Regulation of Ssr1 1 0.44 1.53 0.2 79.84
152 INT203024 Positive_regulation of Positive_regulation of PYY 1 0.38 0.53 0.06 79.80
153 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 79.56
154 INT21744 Positive_regulation of Localization of crf 3 0.12 3.47 1.48 79.44
155 INT21747 Localization of crf 8 0.47 5.32 5.06 79.44
156 INT54740 Positive_regulation of Localization of Crh 10 0.47 7.27 3.01 79.04
157 INT8075 Localization of Crh 64 0.81 25.41 19.45 79.04
158 INT75929 Gene_expression of IL9 61 0.43 24.71 16.17 78.76
159 INT85418 Positive_regulation of Gene_expression of IL9 11 0.38 11.47 9.56 78.76
160 INT97707 Regulation of HMOX2 4 0.18 1.96 1.5 78.32
161 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 78.20
162 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 78.20
163 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 78.20
164 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 78.20
165 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 78.20
166 INT52693 Positive_regulation of Gene_expression of Ptgs2 57 0.70 25.51 21.18 78.20
167 INT76406 Gene_expression of Hmox1 140 0.78 85.86 17.15 78.20
168 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 78.20
169 INT199409 Positive_regulation of Negative_regulation of CYP3A4 7 0.50 2.54 0.41 78.08
170 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 78.08
171 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 77.96
172 INT33009 Gene_expression of Cdk2ap1 6 0.31 6.69 0.33 77.96
173 INT83887 Gene_expression of HMOX2 10 0.77 7.99 3.85 77.88
174 INT25363 Negative_regulation of Trpv1 144 0.59 64.78 75.7 77.80
175 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45 77.80
176 INT9069 Regulation of Htr3a 29 0.60 6.18 16.55 76.36
177 INT52170 Regulation of Cckbr 5 0.58 1.34 3.69 76.36
178 INT68913 Gene_expression of Cd14 55 0.76 38.99 15.67 76.00
179 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 75.84
180 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 75.20
181 INT52690 Positive_regulation of Ptgs2 65 0.68 39.51 30.02 75.20
182 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 75.00
183 INT15358 Transcription of Ngf 29 0.72 10.43 16.94 75.00
184 INT58994 Localization of Mcpt2 7 0.79 3.37 1.3 75.00
185 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 75.00
186 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 75.00
187 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 75.00
188 INT1200 Negative_regulation of Ins1 274 0.58 155.17 56.14 75.00
189 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 75.00
190 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 75.00
191 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 75.00
192 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 75.00
193 INT17546 Negative_regulation of Ngf 135 0.59 60.28 77.19 75.00
194 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 75.00
195 INT4034 Negative_regulation of Gip 16 0.53 6.46 5.65 75.00
196 INT16262 Positive_regulation of Transcription of Ngf 8 0.50 4.02 5.48 75.00
197 INT111514 Positive_regulation of Gene_expression of Mpo 20 0.49 15.13 3.88 75.00
198 INT75713 Positive_regulation of Mcpt2 9 0.69 5.93 2.16 75.00
199 INT73641 Regulation of Lep 45 0.62 26.2 12.59 74.76
200 INT18463 Localization of Pgc 31 0.78 3.74 7.3 74.64
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