D:Gastroparesis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Gastric Stases, GASTRIC STASIS, GASTROPARESES, Stases Gastric, STASIS GASTRIC
Documents 63
Hot Single Events 23
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gastroparesis. They are ordered first by their relevance to Gastroparesis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT82904 Crh Negative_regulation of ge 1 0.00 1.3 0.33 95.16
2 INT91720 Binding of BDNF and CNTF 1 0.09 1.71 0.38 40.40
3 INT91719 Binding of BDNF and LIF 1 0.09 1.65 0.38 39.12
4 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
5 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
6 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
7 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
8 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
9 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
10 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
11 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
12 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
13 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gastroparesis. They are ordered first by their pain relevance and then by number of times they were reported in Gastroparesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6481 Binding of TNF 624 0.48 510.2 214.82 100.00
2 INT6761 Binding of CALCA 100 0.48 26.71 62.05 99.68
3 INT918 Positive_regulation of Localization of PRL 90 0.70 23.97 40.3 99.16
4 INT425 Localization of PRL 455 0.81 189.64 144.8 98.88
5 INT626 Localization of CALCA 289 0.81 125.39 221.15 98.08
6 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 97.48
7 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 97.48
8 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 97.24
9 INT82901 Regulation of ge 2 0.00 1.02 0.25 96.96
10 INT16879 Binding of Crh 72 0.48 21.65 28.43 95.16
11 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 94.84
12 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 94.64
13 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 93.80
14 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 91.48
15 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 90.56
16 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 87.36
17 INT894 Binding of Avp 84 0.48 29.16 29.63 84.48
18 INT5586 Binding of Fos 47 0.48 12.7 21.33 84.48
19 INT5533 Binding of Oxt 43 0.48 8.69 18.35 84.48
20 INT141 Binding of Th 21 0.48 3.53 11.04 84.48
21 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92 84.36
22 INT1562 Localization of Crh 499 0.81 126.74 236.68 83.80
23 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 81.60
24 INT3851 Gene_expression of Got1 58 0.65 29.15 10.52 79.72
25 INT63534 Binding of CRH 23 0.47 6.84 3.43 68.12
26 INT82902 Regulation of Negative_regulation of ge 1 0.00 0.63 0.18 61.52
27 INT79877 Negative_regulation of ge 4 0.34 2.01 0.76 60.16
28 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 58.48
29 INT9358 Positive_regulation of HTR1B 26 0.67 11 17.51 58.08
30 INT194421 Gene_expression of DCLK3 27 0.40 1.26 13.94 57.80
31 INT102448 Gene_expression of RAMP1 23 0.75 4.62 10.9 57.80
32 INT102452 Gene_expression of RAMP2 6 0.69 7.11 3.77 55.16
33 INT141967 Gene_expression of RAMP3 4 0.69 3.35 1.69 55.16
34 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51 50.56
35 INT6021 Binding of PRL 18 0.48 12.55 4.3 43.12
36 INT91721 Binding of IL18 21 0.48 21.17 6.56 42.96
37 INT86437 Binding of IL6 154 0.48 121.22 29.3 42.36
38 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 42.08
39 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 40.88
40 INT194414 Positive_regulation of Gene_expression of RAMP1 4 0.60 0.57 1.89 38.48
41 INT223967 Regulation of Gene_expression of RAMP1 1 0.39 0.5 0.97 38.12
42 INT16964 Binding of IFNG 27 0.48 14.31 2.45 37.96
43 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89 37.20
44 INT253 Regulation of PRL 184 0.62 47.27 65.79 32.04
45 INT29290 Regulation of Gene_expression of PRL 13 0.49 6.46 5.23 32.04
46 INT34889 Regulation of Transcription of PRL 2 0.42 0.55 0.67 32.04
47 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 31.64
48 INT34891 Transcription of PRL 4 0.72 0.69 2.36 31.64
49 INT1898 Regulation of Crh 220 0.62 61.33 102.64 25.00
50 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 18.72
51 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07 17.00
52 INT11244 Transcription of CALCA 21 0.69 3.61 12.27 16.60
53 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76 14.84
54 INT1577 Negative_regulation of Gene_expression of PRL 24 0.59 7.7 3.15 14.80
55 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 14.12
56 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 12.76
57 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 5.00
58 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 5.00
59 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 5.00
60 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
61 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
62 INT397 Localization of SST 232 0.81 58.05 101.19 5.00
63 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 5.00
64 INT5118 Regulation of SST 97 0.62 34.35 51.74 5.00
65 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
66 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
67 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 5.00
68 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
69 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 5.00
70 INT6417 Negative_regulation of ABAT 49 0.51 19.6 36.81 5.00
71 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 5.00
72 INT3913 Positive_regulation of ABAT 47 0.69 22.73 33.4 5.00
73 INT691 Binding of SST 67 0.48 24.66 32.67 5.00
74 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
75 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
76 INT9282 Gene_expression of HTR1B 48 0.75 12.15 22.94 5.00
77 INT7383 Localization of VIP 53 0.81 17.7 22.65 5.00
78 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
79 INT9782 Binding of HTR1B 43 0.47 12.08 19.83 5.00
80 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 5.00
81 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 5.00
82 INT18621 Binding of ABAT 28 0.36 9.88 18.04 5.00
83 INT50403 Negative_regulation of CYP2C19 55 0.59 8.97 17.79 5.00
84 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
85 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46 5.00
86 INT50404 Negative_regulation of CYP1A2 49 0.59 8.61 17.35 5.00
87 INT1578 Negative_regulation of Localization of PRL 52 0.59 20.62 17.18 5.00
88 INT59929 Negative_regulation of CYP2C9 60 0.59 16.33 15.39 5.00
89 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
90 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 5.00
91 INT7587 Localization of GAL 27 0.78 4.79 14.29 5.00
92 INT22272 Negative_regulation of HTR2A 28 0.57 7.62 13.87 5.00
93 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 5.00
94 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 5.00
95 INT86464 Binding of LMOD1 31 0.44 10.23 10.46 5.00
96 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 5.00
97 INT31780 Binding of DIO2 17 0.36 10.07 10 5.00
98 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
99 INT92777 Positive_regulation of Gene_expression of ABAT 13 0.44 7.49 9.27 5.00
100 INT94196 Negative_regulation of Phosphorylation of MAPK1 60 0.59 31.64 9.16 5.00
101 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 5.00
102 INT10237 Binding of EDN1 40 0.48 16 8.48 5.00
103 INT29121 Positive_regulation of DIO2 23 0.67 6.13 8.46 5.00
104 INT15459 Gene_expression of TRH 17 0.78 4.89 8.17 5.00
105 INT4487 Positive_regulation of Positive_regulation of PRL 27 0.70 8.06 8.09 5.00
106 INT6957 Positive_regulation of OXTR 38 0.70 6.55 7.81 5.00
107 INT90461 Negative_regulation of DRD2 21 0.53 8.35 6.55 5.00
108 INT24191 Binding of VIP 14 0.40 2.16 6.2 5.00
109 INT144735 Gene_expression of DDC 8 0.75 3.21 5.31 5.00
110 INT58750 Binding of GAL 16 0.47 5.48 4.92 5.00
111 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73 5.00
112 INT36309 Negative_regulation of DIO2 18 0.57 6.42 4.51 5.00
113 INT4485 Negative_regulation of Positive_regulation of PRL 11 0.43 4.24 3.89 5.00
114 INT116220 Localization of HTR1B 5 0.78 1.86 3.75 5.00
115 INT76092 Localization of ISYNA1 10 0.66 7.72 3.11 5.00
116 INT101342 Negative_regulation of CYP2A6 11 0.53 3.68 2.39 5.00
117 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92 5.00
118 INT4028 Regulation of HYAL1 8 0.54 1.55 1.8 5.00
119 INT155764 Binding of SPINT2 2 0.06 0.12 1.54 5.00
120 INT31047 Localization of HRH2 5 0.75 1.84 1.53 5.00
121 INT303913 Regulation of Regulation of CYP2D6 2 0.37 1.09 1.48 5.00
122 INT121136 Negative_regulation of DDC 4 0.57 2.98 1.32 5.00
123 INT232445 Positive_regulation of Transcription of PRL 1 0.50 0 1.32 5.00
124 INT58311 Regulation of Localization of EGF 3 0.54 1.06 1.16 5.00
125 INT39955 Positive_regulation of Negative_regulation of PRL 3 0.70 0.47 0.9 5.00
126 INT232442 Negative_regulation of Gene_expression of DDC 1 0.05 1.44 0.58 5.00
127 INT110319 Positive_regulation of SRGN 10 0.40 6.2 0.56 5.00
128 INT232453 Negative_regulation of DNAJA3 1 0.41 0 0.54 5.00
129 INT232449 Negative_regulation of Transcription of PRL 1 0.59 0 0.3 5.00
130 INT166403 Gene_expression of SPINT2 4 0.62 2.74 0.29 5.00
131 INT232452 Positive_regulation of Binding of PRL 1 0.50 0.18 0.27 5.00
132 INT232444 Regulation of Localization of GAL 1 0.44 0.28 0.27 5.00
133 INT232448 Positive_regulation of Gene_expression of TRH 1 0.32 0.08 0.17 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox