D:Genetic Predisposition To Disease

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Disease Term
Synonyms Genetic Predisposition, Genetic Predispositions, Genetic Susceptibilities, Genetic Susceptibility, Predisposition Genetic, Predispositions Genetic, Susceptibilities Genetic, SUSCEPTIBILITY GENETIC
Documents 993
Hot Single Events 200
Hot Interactions 25

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Genetic Predisposition To Disease. They are ordered first by their relevance to Genetic Predisposition To Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09 100.00
2 INT139404 Binding of TNF and SFTPA1 1 0.00 0.51 0.1 100.00
3 INT252020 Binding of HLA-A and ELOVL1 1 0.01 1.41 0 99.10
4 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 98.68
5 INT230065 Binding of TOR1A and HLA-DOA 1 0.00 1.65 0.09 98.48
6 INT171939 Binding of HLA-DOA and TNF 1 0.05 6.8 0.26 98.08
7 INT243119 Binding of amd and Sod2 1 0.29 3.25 0.06 95.96
8 INT270656 Binding of Il21 and Idd3 1 0.30 0.92 0 95.36
9 INT270660 Binding of Il2 and Idd3 1 0.29 0.92 0 95.36
10 INT238034 Binding of DMD and SNRNP70 1 0.00 1.18 0.04 92.88
11 INT172048 Binding of TNF and MICA 1 0.29 1.63 0.62 91.64
12 INT288497 Binding of Tlr7 and Tlr9 1 0.21 0.97 0.27 91.04
13 INT136606 Binding of RAN and DLL1 1 0.33 0.45 0.15 91.00
14 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 90.76
15 INT136605 Binding of OPRD1 and RAN 1 0.37 0.54 0.15 90.64
16 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 90.40
17 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26 88.80
18 INT54992 Il6 Negative_regulation of Prl 1 0.00 0.86 0.84 88.48
19 INT338430 Cd4 Negative_regulation of Gene_expression of Ik 1 0.01 1.27 0.22 88.20
20 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 88.04
21 INT338421 Il2ra Negative_regulation of Gene_expression of Ik 1 0.00 1.27 0.22 88.00
22 INT298688 Binding of OPA1 and MFN1 1 0.52 2.09 0 81.28
23 INT298687 Binding of OPA1 and PARL 1 0.50 2.09 0 81.28
24 INT284481 Binding of ABCA1 and Ighg1 1 0.00 1.39 0.7 80.92
25 INT246414 TLR4 Regulation of Gene_expression of TLR3 1 0.35 1.16 0.17 80.88
26 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 79.36
27 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 79.36
28 INT271003 Binding of TBXA2R and Aia1 1 0.01 1.81 0.14 78.28
29 INT355541 Binding of AMELX and Tnfrsf25 1 0.00 1.36 0 77.92
30 INT355522 Binding of AMELX and HLA-DRB7 1 0.00 1.35 0 77.92
31 INT191923 Binding of EXOSC10 and Tlr4 1 0.21 0.48 0.04 77.32
32 INT324068 Binding of GCH1 and SNRNP70 1 0.01 28.19 40.6 75.76
33 INT17726 Positive_regulation of Binding of AKR1A1 and Aldh2 1 0.11 0.35 0.41 75.00
34 INT17725 Binding of AKR1A1 and Aldh2 1 0.08 0.35 0.4 75.00
35 INT299556 SQLE Regulation of CRS 1 0.00 0.77 0.03 72.48
36 INT242301 Binding of EGFR and ACCS 1 0.11 1.31 0 72.44
37 INT223158 Mapk3 Regulation of Gene_expression of Mapk14 1 0.48 1.33 0.59 72.12
38 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47 71.64
39 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 67.84
40 INT246413 TLR4 Regulation of TLR3 1 0.28 0.81 0.05 66.84
41 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 64.16
42 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 64.16
43 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 63.80
44 INT335850 Snrpc Negative_regulation of Gene_expression of Isl1 1 0.00 1.51 0.45 63.24
45 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16 62.76
46 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43 62.76
47 INT354482 Binding of PRNP and Prnp 1 0.16 0.88 0 59.68
48 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98 59.44
49 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68 59.44
50 INT244687 Mmp14 Positive_regulation of Mmp2 1 0.23 0.48 0.25 56.56
51 INT285568 Binding of TNF and Tnfsf10 1 0.12 1.39 0.36 52.64
52 INT223155 Binding of Mapk14 and Stat4 1 0.36 0.84 0.63 51.40
53 INT341308 Negative_regulation of Npc1 Positive_regulation of Gene_expression of Srebf1 1 0.31 1.48 0 50.96
54 INT342385 Positive_regulation of Binding of Lrp5 and Vdr 1 0.53 0.98 0 50.00
55 INT342387 Binding of CALCR and Car1 1 0.11 0.83 0 50.00
56 INT342378 Binding of Vdr and Best1 1 0.05 0.4 0 50.00
57 INT342383 Binding of Srp14 and Best1 1 0.00 0.56 0 50.00
58 INT215470 Binding of HLA-B and CRAMP1L 1 0.05 0.94 0 50.00
59 INT342381 Binding of Lrp5 and Vdr 1 0.55 0.97 0 50.00
60 INT342382 Binding of Car1 and Lrp5 1 0.40 0.9 0 50.00
61 INT342388 Binding of CALCR and Vdr 1 0.12 0.83 0 50.00
62 INT254434 Binding of Lrp5 and Best1 3 0.29 2.53 0 50.00
63 INT342379 Binding of Car1 and Sugt1 1 0.01 0.83 0 50.00
64 INT342386 Binding of CALCR and Best1 1 0.01 0.96 0 50.00
65 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35 48.84
66 INT263249 Binding of ADD1 and REN 1 0.03 0.82 0 48.80
67 INT299592 SQLE Regulation of RatNP-3b 1 0.01 0.99 0.22 46.16
68 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 46.08
69 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 45.40
70 INT350121 INS Negative_regulation of Positive_regulation of SHBG 1 0.09 1.48 0.04 45.40
71 INT350118 INS Negative_regulation of SHBG 1 0.09 1.42 0.04 45.40
72 INT301178 UCP2 Negative_regulation of ROS1 1 0.29 1.41 0 44.48
73 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59 42.20
74 INT352525 SLC25A16 Negative_regulation of SMO 1 0.00 1.1 0 40.96
75 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0 40.64
76 INT240685 Binding of DIRAS3 and KCNQ4 1 0.18 0.95 0 37.12
77 INT240684 Binding of NAT2 and DIRAS3 1 0.03 0.95 0 37.12
78 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5 36.24
79 INT263248 Binding of ADD1 and RAPGEF5 1 0.01 0.84 0 34.64
80 INT353106 Binding of amd and C3 1 0.09 1.69 0 34.60
81 INT324067 Regulation of Binding of GCH1 and SNRNP70 1 0.01 0.95 1.67 32.64
82 INT335514 NR1I2 Regulation of Gene_expression of ABCB1 1 0.66 2.42 0.54 32.16
83 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17 29.84
84 INT250853 Binding of Fgf1 and Mtpn 1 0.00 0.28 0.21 29.80
85 INT261977 Binding of HLA-A and PDCD1 1 0.07 0.52 0 29.48
86 INT261978 Binding of HLA-DRB4 and PDCD1 1 0.23 0.51 0 29.48
87 INT162396 Binding of LCE3B and LCE3C 1 0.32 1.08 0.45 28.44
88 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0 27.84
89 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 25.00
90 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 25.00
91 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 25.00
92 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 25.00
93 INT354789 Tnc Regulation of HSPG2 1 0.02 1.38 0 25.00
94 INT151902 PLG Positive_regulation of Protein_catabolism of F13A1 1 0.00 0.16 0 25.00
95 INT353104 Binding of amd and Gtf3a 1 0.01 1.53 0.03 20.40
96 INT322812 Binding of SLC12A1 and MOCOS 1 0.00 1.69 1.49 20.32
97 INT270666 Binding of Idd6 and Idd19 1 0.37 0.8 0.05 17.32
98 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4 15.60
99 INT172047 Binding of HLA-A and LRRC23 1 0.22 3.32 1.64 15.60
100 INT261976 Binding of PDCD1 and SUGT1 1 0.00 1.3 0.25 10.20
101 INT269014 Binding of EGR1 and COPD 1 0.12 0.96 0 7.12
102 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12 6.56
103 INT289510 Binding of ODF2 and Ezr 1 0.10 0.47 0 5.76
104 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
105 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
106 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 5.00
107 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
108 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
109 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
110 INT86179 TNF Positive_regulation of Localization of IL6 5 0.35 1.66 2.17 5.00
111 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14 5.00
112 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
113 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
114 INT203044 Binding of PDCD1 and DTHD1 1 0.02 3.19 1.87 5.00
115 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 5.00
116 INT172206 Binding of Slc6a3 and ADHD1 2 0.03 2.76 1.61 5.00
117 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 5.00
118 INT172203 Binding of Comt and Maoa 1 0.31 0.98 1.43 5.00
119 INT223156 Il6 Regulation of A2m 1 0.11 2.79 1.39 5.00
120 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
121 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 5.00
122 INT223154 Negative_regulation of Mapk14 Negative_regulation of Localization of Il6 1 0.19 1.13 1.11 5.00
123 INT223157 Abat Negative_regulation of Localization of Il6 1 0.05 1.13 1.1 5.00
124 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
125 INT38936 Binding of Avp and Crh 7 0.40 0.82 1.04 5.00
126 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
127 INT322808 Binding of RS1 and MOCOS 1 0.00 0.86 1.01 5.00
128 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 5.00
129 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99 5.00
130 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99 5.00
131 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98 5.00
132 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96 5.00
133 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93 5.00
134 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
135 INT215650 Binding of Adora1 and Drd1a 2 0.39 0.54 0.92 5.00
136 INT250976 Binding of FMOD and IL8 1 0.08 1.26 0.91 5.00
137 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9 5.00
138 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
139 INT277832 Binding of TNFRSF1B and NPEPPS 1 0.01 1.1 0.88 5.00
140 INT277831 Binding of TNFRSF1A and NPEPPS 1 0.01 1.1 0.87 5.00
141 INT323698 Gene_expression of MIR146A Regulation of FAF1 1 0.16 1.82 0.86 5.00
142 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
143 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84 5.00
144 INT250861 Fgf8 Positive_regulation of Gene_expression of Ptger2 1 0.04 1.51 0.84 5.00
145 INT271511 Binding of Phb2 and Glrb 1 0.04 1.7 0.84 5.00
146 INT282506 ocd Positive_regulation of Gene_expression of Comt 1 0.32 1.26 0.84 5.00
147 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
148 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79 5.00
149 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77 5.00
150 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73 5.00
151 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72 5.00
152 INT237325 Il6 Positive_regulation of Gene_expression of Ik 2 0.00 2.09 0.72 5.00
153 INT187171 Binding of Tnfrsf1b and Gtf3a 1 0.03 2.15 0.72 5.00
154 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69 5.00
155 INT134652 Binding of MC1R and SUGT1 1 0.02 0.84 0.68 5.00
156 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68 5.00
157 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 5.00
158 INT285562 Binding of Il27ra and Il27 1 0.10 2.19 0.67 5.00
159 INT194618 Il17a Positive_regulation of Gene_expression of IL8 2 0.01 1.94 0.67 5.00
160 INT270762 IL1B Positive_regulation of IL1B Negative_regulation of IKBKB 1 0.02 1.13 0.66 5.00
161 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66 5.00
162 INT221847 Binding of Calca and Ntrk1 1 0.03 0.9 0.65 5.00
163 INT45780 GNRH1 Positive_regulation of PLOD1 3 0.07 1.02 0.63 5.00
164 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 5.00
165 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61 5.00
166 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
167 INT203056 Binding of Cd274 and PDCD1LG2 1 0.13 1.61 0.57 5.00
168 INT203041 Binding of CD274 and PDCD1LG2 1 0.03 1.61 0.57 5.00
169 INT228497 Il4 Regulation of Ncoa5 1 0.01 1.24 0.57 5.00
170 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 5.00
171 INT311179 CNR1 Negative_regulation of Transcription of CNR2 1 0.41 2.05 0.55 5.00
172 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54 5.00
173 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54 5.00
174 INT54584 GNRH1 Positive_regulation of FSHR 3 0.48 2.02 0.54 5.00
175 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51 5.00
176 INT322811 Binding of GRIA1 and RS1 1 0.00 0.43 0.51 5.00
177 INT132442 Binding of RHAG and EFHC1 1 0.36 1.2 0.51 5.00
178 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5 5.00
179 INT132443 Binding of MEP1A and EFHC1 1 0.44 1.19 0.5 5.00
180 INT335851 Snrpc Positive_regulation of Il10 1 0.01 1.17 0.5 5.00
181 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5 5.00
182 INT297152 Binding of PRTN3 and SNRNP70 1 0.40 1.27 0.5 5.00
183 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48 5.00
184 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48 5.00
185 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47 5.00
186 INT338940 Fpgs Positive_regulation of Mtx1 1 0.32 0.32 0.47 5.00
187 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47 5.00
188 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47 5.00
189 INT338426 Binding of Hand1 and Hand2 2 0.06 2 0.46 5.00
190 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 5.00
191 INT352387 Binding of CFP and HPSE 1 0.01 1.25 0.46 5.00
192 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 5.00
193 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44 5.00
194 INT355540 Gnptg Positive_regulation of AMELX 1 0.00 2.16 0.44 5.00
195 INT246024 IL23A Positive_regulation of SOCS2 1 0.01 0.99 0.43 5.00
196 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 5.00
197 INT246023 IL6 Positive_regulation of SOCS2 1 0.18 0.99 0.43 5.00
198 INT230437 Binding of PDX1 and HRCT1 1 0.04 2.45 0.43 5.00
199 INT323702 HGF Regulation of Gene_expression of CRP 1 0.01 0.81 0.43 5.00
200 INT331799 IL8 Negative_regulation of Mapk14 1 0.01 1.6 0.42 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Genetic Predisposition To Disease. They are ordered first by their pain relevance and then by number of times they were reported in Genetic Predisposition To Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT46405 Negative_regulation of Gene_expression of ATN1 1 0.41 2.58 0.69 100.00
2 INT46402 Negative_regulation of Gene_expression of DONSON 1 0.04 2.58 0.69 100.00
3 INT46401 Negative_regulation of ATN1 1 0.41 2.57 0.69 100.00
4 INT46410 Negative_regulation of DONSON 1 0.04 2.57 0.69 100.00
5 INT46404 Negative_regulation of NDUFA5 1 0.18 2.57 0.69 100.00
6 INT17312 Binding of HSPG2 30 0.41 33.01 4.88 100.00
7 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 100.00
8 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 100.00
9 INT3925 Negative_regulation of HLA-B 29 0.42 20.19 9.46 100.00
10 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84 100.00
11 INT240359 Binding of Tnc 2 0.35 11.67 1.48 100.00
12 INT149051 Regulation of Il23r 1 0.26 0.37 0.17 100.00
13 INT110269 Binding of Gabbr1 2 0.36 2.1 2.18 99.84
14 INT244657 Regulation of Lch 3 0.40 6.63 0.13 99.80
15 INT270619 Positive_regulation of Il21r 1 0.32 0.89 0 99.76
16 INT288491 Positive_regulation of Transcription of Tlr3 1 0.37 1.85 0.19 99.72
17 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 99.68
18 INT181413 Regulation of Lck 2 0.36 2.54 0.33 99.68
19 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 99.62
20 INT162793 Regulation of NOD2 6 0.45 7.61 1.78 99.60
21 INT46406 Binding of DONSON 1 0.03 2.54 0.68 99.60
22 INT46407 Binding of ATN1 4 0.36 5.85 1.81 99.60
23 INT145077 Regulation of SLC22A5 2 0.19 3 1.1 99.60
24 INT177997 Regulation of SLC22A4 2 0.20 3.88 0.86 99.60
25 INT246029 Regulation of IL23R 1 0.21 2.83 0.35 99.60
26 INT246027 Regulation of ATG16L1 1 0.24 2.82 0.35 99.60
27 INT64451 Negative_regulation of MC1R 21 0.59 4.94 9.22 99.48
28 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.46
29 INT345415 Positive_regulation of Cltc 1 0.11 1.06 0.17 99.46
30 INT288489 Transcription of Tlr3 1 0.51 3.85 1.05 99.42
31 INT63905 Regulation of RB1 13 0.62 12.67 1.28 99.40
32 INT86437 Binding of IL6 154 0.48 121.22 29.3 99.36
33 INT224636 Positive_regulation of Il21 6 0.45 6.16 1.97 99.36
34 INT18114 Gene_expression of NPC1 45 0.66 57.85 1.44 99.28
35 INT46409 Gene_expression of NDUFA5 2 0.29 4.76 1.18 99.26
36 INT104502 Gene_expression of Abcc2 26 0.78 8.37 9.65 99.22
37 INT44466 Gene_expression of Ugt2b7 7 0.75 1.32 2 99.22
38 INT65880 Gene_expression of CYP2C8 25 0.77 9.49 1.92 99.22
39 INT46408 Gene_expression of DONSON 1 0.06 2.54 0.68 99.16
40 INT46403 Gene_expression of ATN1 2 0.75 3.33 0.93 99.04
41 INT342470 Negative_regulation of Gene_expression of Ath9 1 0.06 1.52 0.04 99.04
42 INT9210 Regulation of IL6 166 0.62 125.61 49.95 99.00
43 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 98.96
44 INT70970 Binding of COPD 144 0.42 180.34 18.29 98.96
45 INT38930 Regulation of IL36RN 4 0.21 2.14 1.8 98.96
46 INT143125 Binding of FLT1 48 0.40 13.6 0.51 98.92
47 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 98.86
48 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 98.78
49 INT261118 Binding of Tnfrsf10b 3 0.07 4.03 0.1 98.68
50 INT50080 Binding of APOE 38 0.45 29.61 2.67 98.56
51 INT72141 Binding of Apoe 11 0.37 10.91 3.27 98.56
52 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 98.44
53 INT62916 Gene_expression of HTR1F 12 0.75 3.25 5.24 98.44
54 INT9660 Regulation of TNF 363 0.62 312.94 139.99 98.32
55 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 98.28
56 INT230087 Binding of TOR1A 6 0.35 2.84 0.68 98.28
57 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 98.24
58 INT14690 Localization of CSF2 124 0.80 85.17 27.26 98.24
59 INT185501 Localization of NEU2 4 0.02 1.08 1.04 98.24
60 INT185504 Localization of PREP 3 0.68 0.92 0.43 98.24
61 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 98.22
62 INT76227 Binding of NPC1 30 0.41 32.31 4.05 98.20
63 INT138652 Negative_regulation of Mthfr 13 0.54 7.3 2.88 98.12
64 INT155639 Regulation of Negative_regulation of Mthfr 1 0.56 0.76 0.66 98.12
65 INT211363 Positive_regulation of RENBP 13 0.22 13.26 6.48 98.04
66 INT35359 Negative_regulation of LCT 23 0.59 9.13 2.29 97.72
67 INT293904 Regulation of TPH2 4 0.54 2.19 0.65 97.68
68 INT342474 Gene_expression of Ath9 1 0.10 1.45 0.04 97.68
69 INT6481 Binding of TNF 624 0.48 510.2 214.82 97.64
70 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 97.56
71 INT39948 Binding of FLNA 45 0.42 58.05 4.27 97.56
72 INT72890 Positive_regulation of Gene_expression of Fcer2a 12 0.17 6.81 2.25 97.46
73 INT39417 Gene_expression of Fcer2a 65 0.76 32.1 7.37 97.30
74 INT46646 Localization of FLNA 19 0.73 18.83 2.53 97.12
75 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 97.12
76 INT282775 Regulation of Positive_regulation of CD4 2 0.37 1.28 0.3 97.12
77 INT78999 Binding of AKR1C1 3 0.36 1.75 0.58 97.08
78 INT288487 Gene_expression of Tlr6 1 0.44 3.93 0.5 97.04
79 INT142049 Regulation of Mthfr 6 0.41 4.73 2 96.96
80 INT127670 Positive_regulation of ARSD 8 0.54 1.75 1.33 96.88
81 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 96.84
82 INT241191 Positive_regulation of Kctd1 2 0.06 4.28 0.16 96.80
83 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 96.78
84 INT140858 Negative_regulation of SUGT1 9 0.05 8.41 1.4 96.64
85 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 96.52
86 INT178841 Localization of SNRNP70 27 0.78 10.35 1.71 96.28
87 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 96.24
88 INT56286 Binding of HLA-DRB6 2 0.01 2.12 0.52 96.24
89 INT101013 Regulation of HLA-A 7 0.33 6.7 1.8 96.12
90 INT301189 Binding of UCP2 1 0.37 1.39 0.04 96.08
91 INT301190 Positive_regulation of Binding of UCP2 1 0.50 0.89 0 96.08
92 INT236282 Transcription of Nppa 2 0.29 0.93 0.19 95.80
93 INT219610 Protein_catabolism of SAA1 2 0.90 4.47 0.54 95.68
94 INT59342 Negative_regulation of NPC1 20 0.44 20.21 2.79 95.68
95 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 95.64
96 INT118734 Gene_expression of Tlr4 70 0.78 55.7 28.19 95.52
97 INT288482 Gene_expression of Tlr5 1 0.43 1 0.09 95.52
98 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76 95.36
99 INT235930 Regulation of Binding of 1 0.05 3.93 0.68 95.36
100 INT20205 Binding of IgG 108 0.46 66.68 8.57 95.36
101 INT143337 Binding of Aqp4 30 0.40 23.73 4.24 95.36
102 INT23401 Gene_expression of HLA-DOA 91 0.30 38.21 5.52 95.32
103 INT156997 Localization of NPC1 19 0.64 30 0.42 95.20
104 INT626 Localization of CALCA 289 0.81 125.39 221.15 95.20
105 INT230097 Gene_expression of TOR1A 1 0.12 2.93 0.17 95.16
106 INT228007 Binding of GLC1N 3 0.24 0.74 0.03 95.12
107 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 95.08
108 INT130762 Binding of VTA1 2 0.26 1.16 1.19 95.04
109 INT169454 Binding of ATD 2 0.21 2.51 0.86 95.04
110 INT88559 Negative_regulation of Spink1 25 0.56 21.81 9.28 94.84
111 INT55093 Negative_regulation of SPINK1 13 0.42 15.11 3.8 94.84
112 INT16404 Regulation of CD4 54 0.61 33.05 10.29 94.80
113 INT16405 Regulation of CD8A 38 0.45 19.04 5.31 94.80
114 INT10870 Regulation of IgG 67 0.59 43.27 12.74 94.72
115 INT235936 Regulation of Regulation of NMO-IgG 1 0.05 1.97 0.34 94.72
116 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 94.64
117 INT97596 Localization of S100a8 94 0.78 90.69 40.41 94.64
118 INT61253 Negative_regulation of Sele 13 0.57 11.68 3.56 94.60
119 INT193499 Negative_regulation of Localization of Sele 1 0.39 1.53 0 94.60
120 INT5539 Negative_regulation of Mme 75 0.59 28.91 41.84 94.56
121 INT121683 Gene_expression of Hc 23 0.75 7.15 2.7 94.56
122 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 94.40
123 INT270999 Positive_regulation of Gene_expression of CYSLTR2 1 0.44 2.81 0.27 94.36
124 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 94.08
125 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 94.08
126 INT64980 Positive_regulation of Localization of Ptafr 2 0.05 2.36 0.54 94.08
127 INT235950 Regulation of Regulation of Aqp4 1 0.37 1.96 0.34 94.08
128 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97 94.04
129 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08 94.04
130 INT1938 Positive_regulation of DONSON 3 0.13 3.02 1.07 94.04
131 INT193498 Localization of Sele 1 0.69 1.52 0 94.04
132 INT13634 Gene_expression of CYSLTR1 19 0.75 11.24 2.88 93.96
133 INT95917 Gene_expression of CYSLTR2 10 0.64 6.1 0.82 93.96
134 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 93.88
135 INT216428 Negative_regulation of UCP2 2 0.43 3.37 0.03 93.88
136 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 93.84
137 INT244676 Binding of Mmp16 1 0.46 1.57 0.17 93.84
138 INT3213 Gene_expression of Ins1 511 0.76 357.59 53.32 93.84
139 INT74250 Negative_regulation of Gene_expression of Ins1 47 0.40 39.27 5.37 93.84
140 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 93.80
141 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 93.76
142 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 93.72
143 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 93.68
144 INT10505 Gene_expression of Ptafr 18 0.62 10.7 6.83 93.68
145 INT34644 Binding of HLA-C 19 0.47 9.41 2.2 93.68
146 INT6934 Binding of OPRD1 51 0.48 7.72 25.73 93.52
147 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 93.40
148 INT12243 Positive_regulation of PRSS1 91 0.70 52.87 19.48 93.40
149 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 93.40
150 INT36554 Gene_expression of PRSS1 70 0.78 50.25 15.33 93.40
151 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 93.24
152 INT812 Localization of INS 1026 0.81 515.6 145.31 93.16
153 INT55343 Localization of Ros1 39 0.60 34.51 12.5 93.12
154 INT54701 Localization of Ptafr 19 0.49 18.68 3.82 93.12
155 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 93.08
156 INT182667 Binding of DLAT 11 0.31 40.75 2.8 93.04
157 INT15692 Regulation of HTC2 4 0.27 4.75 1.61 92.84
158 INT138673 Regulation of Gene_expression of TPH2 3 0.62 1.23 1.42 92.72
159 INT182334 Binding of Glrb 3 0.28 4.81 1.71 92.64
160 INT227402 Positive_regulation of Negative_regulation of Trbv26 1 0.49 2.04 0.11 92.64
161 INT227403 Positive_regulation of Negative_regulation of Tcrb 1 0.06 2.04 0.11 92.64
162 INT147584 Localization of AIS 38 0.63 12.83 5.27 92.60
163 INT171998 Binding of DMD 58 0.47 38.13 3.35 92.60
164 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 92.52
165 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 92.52
166 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 92.36
167 INT6307 Positive_regulation of HTR1D 17 0.67 3.11 7.51 92.28
168 INT145756 Gene_expression of Tlr2 23 0.74 20.77 5.18 92.16
169 INT138671 Gene_expression of TPH2 35 0.78 7.34 6.03 92.16
170 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 92.12
171 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 92.04
172 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 92.00
173 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 91.96
174 INT20664 Binding of ACE 60 0.48 35.27 9.16 91.92
175 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75 91.84
176 INT78281 Gene_expression of Krt7 28 0.70 26.77 0.97 91.80
177 INT15797 Positive_regulation of HLA-E 36 0.67 15.17 5.07 91.76
178 INT339592 Regulation of ARMS2 2 0.26 2.27 0 91.76
179 INT136611 Positive_regulation of Binding of HTR1D 1 0.48 0.45 0.15 91.72
180 INT101923 Binding of MICA 6 0.48 5.44 0.71 91.64
181 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 91.60
182 INT43985 Regulation of LPA 29 0.62 20.79 3.29 91.60
183 INT207818 Positive_regulation of Kcnj11 2 0.48 1.67 0.07 91.60
184 INT210256 Positive_regulation of Tcf7l2 2 0.28 1.25 0 91.60
185 INT288493 Positive_regulation of Gene_expression of Tlr2 4 0.66 4.38 0.94 91.56
186 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 91.56
187 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 91.52
188 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 91.52
189 INT128353 Negative_regulation of Car3 16 0.37 4.93 4.61 91.44
190 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 91.36
191 INT227404 Negative_regulation of Trbv26 1 0.41 2.03 0.11 91.36
192 INT151747 Positive_regulation of PSMD2 26 0.68 17.48 17.89 91.32
193 INT93739 Positive_regulation of Gene_expression of Tnfrsf1a 11 0.66 11.17 4.44 91.28
194 INT215454 Regulation of amd 4 0.38 8.07 0.29 91.12
195 INT120599 Binding of Tlr7 2 0.27 2.16 0.96 91.04
196 INT159119 Negative_regulation of Car1 17 0.37 6.6 4.01 91.04
197 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 91.00
198 INT40036 Binding of DLL1 10 0.36 2.88 3.95 91.00
199 INT136609 Positive_regulation of Binding of DLL1 1 0.49 0.45 0.15 91.00
200 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 90.96
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