D:Gilbert Syndrome

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pChart

Disease Term
Synonyms Benign Unconjugated Bilirubinaemia Syndrome, BENIGN UNCONJUGATED BILIRUBINEMIA SYNDROME, Cholaemia Familiaris Simplex, Cholemia Familiaris Simplex, Chronic Intermittent Juvenile Jaundice, Chronic Unconjugated Hyperbilirubinaemia, Chronic Unconjugated Hyperbilirubinemia, Congenital Nonhaemolytic Jaundice, Congenital Nonhemolytic Jaundice, Constitutional Hepatic Dysfunction, CONSTITUTIONAL HEPATIC DYSFUNCTION SYNDROME
Documents 9
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gilbert Syndrome. They are ordered first by their relevance to Gilbert Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 5.00
2 INT190684 Binding of A2M and IGF1 1 0.16 1.54 0.1 5.00
3 INT223283 Binding of CYP2C9 and VKORC1 1 0.31 0.16 0 5.00
4 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 5.00
5 INT347226 Hck Regulation of Gene_expression of Lyn 1 0.10 0.08 0 5.00
6 INT347225 Hck Regulation of Positive_regulation of Bcr 1 0.15 0.07 0 5.00
7 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gilbert Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Gilbert Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT347222 Gene_expression of Ugt1a1 1 0.44 0.28 0 97.04
2 INT347218 Positive_regulation of Gene_expression of Ugt1a1 1 0.32 0.28 0 97.04
3 INT251082 Gene_expression of Serpina3c 2 0.65 2.3 0.07 96.72
4 INT347220 Positive_regulation of Gene_expression of Serpina3c 1 0.49 0.28 0 96.72
5 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 77.60
6 INT266627 Positive_regulation of Ugt1a2 3 0.04 5.54 0.56 76.72
7 INT347219 Positive_regulation of Dleu2 1 0.67 1.59 0.14 73.04
8 INT78889 Binding of UGT1A1 10 0.47 3.41 1.47 71.84
9 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64 70.48
10 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 59.32
11 INT106261 Negative_regulation of DPYD 16 0.59 15.02 1.19 49.20
12 INT223288 Protein_catabolism of DPYD 1 0.46 0.11 0 33.68
13 INT117031 Binding of Samsn1 6 0.21 6.82 0.76 29.48
14 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 27.56
15 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 26.96
16 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02 24.00
17 INT41890 Positive_regulation of Gene_expression of FOXG1 2 0.32 1.04 0.09 24.00
18 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
19 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
20 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
21 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
22 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 5.00
23 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
24 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
25 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
26 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
27 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
28 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 5.00
29 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
30 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
31 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
32 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 5.00
33 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 5.00
34 INT10798 Positive_regulation of CYP2D6 24 0.56 5.82 11.31 5.00
35 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 5.00
36 INT75137 Regulation of Akt1 74 0.48 37.89 9.7 5.00
37 INT13467 Positive_regulation of ABCB1 36 0.68 9.68 8.95 5.00
38 INT82839 Negative_regulation of ABCB1 61 0.59 16.09 8.83 5.00
39 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 5.00
40 INT66819 Binding of CYP2C9 41 0.48 8.23 8.76 5.00
41 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
42 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83 5.00
43 INT7883 Binding of ADRB2 18 0.47 5.49 7.37 5.00
44 INT110987 Transcription of ESR1 45 0.71 24.16 6.72 5.00
45 INT69561 Positive_regulation of GSTM1 23 0.50 5.69 6.36 5.00
46 INT163756 Phosphorylation of Stat1 45 0.82 14.51 6.11 5.00
47 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 5.00
48 INT103518 Negative_regulation of SCN2A 17 0.57 8.4 5.4 5.00
49 INT78914 Positive_regulation of ABCC1 19 0.67 7.99 5.18 5.00
50 INT60957 Negative_regulation of Abcb1b 18 0.57 6 4.73 5.00
51 INT80983 Regulation of Abcb1b 16 0.60 1.95 4.32 5.00
52 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17 5.00
53 INT75136 Binding of Akt1 27 0.27 8.81 4.15 5.00
54 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
55 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 5.00
56 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49 5.00
57 INT15299 Gene_expression of IL1RL1 37 0.69 10.09 3.43 5.00
58 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 5.00
59 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 5.00
60 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
61 INT212394 Gene_expression of Zic2 44 0.78 2.88 2.82 5.00
62 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5 5.00
63 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45 5.00
64 INT62653 Positive_regulation of CYP2C19 8 0.54 1.23 2.41 5.00
65 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92 5.00
66 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86 5.00
67 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 5.00
68 INT140175 Regulation of Kit 23 0.62 8.59 1.79 5.00
69 INT180185 Gene_expression of MGMT 22 0.65 15.02 1.57 5.00
70 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
71 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 5.00
72 INT86446 Protein_catabolism of Lipg 9 0.50 3.52 1.25 5.00
73 INT155838 Binding of GGT1 7 0.47 13.27 1.11 5.00
74 INT94690 Gene_expression of DPYD 12 0.75 4.6 1.07 5.00
75 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98 5.00
76 INT12555 Binding of ADRB1 7 0.39 3.78 0.97 5.00
77 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96 5.00
78 INT241499 Binding of Abl1 23 0.47 8.86 0.75 5.00
79 INT199573 Gene_expression of Abl1 33 0.65 20.79 0.75 5.00
80 INT145932 Gene_expression of Hck 5 0.77 2.69 0.73 5.00
81 INT189322 Binding of A2M 7 0.29 12.1 0.66 5.00
82 INT144024 Negative_regulation of Phosphorylation of Pdgfrb 6 0.42 3.48 0.51 5.00
83 INT20239 Regulation of APOA1 10 0.60 10.98 0.51 5.00
84 INT273550 Positive_regulation of Bcr 14 0.68 6.71 0.49 5.00
85 INT199553 Gene_expression of Bcr 25 0.76 13.83 0.48 5.00
86 INT126683 Localization of Lipg 7 0.70 3.87 0.46 5.00
87 INT273555 Negative_regulation of Bcr 17 0.57 9.65 0.44 5.00
88 INT213789 Phosphorylation of Kit 7 0.69 5.32 0.43 5.00
89 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42 5.00
90 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39 5.00
91 INT273556 Phosphorylation of Crkl 9 0.37 8.43 0.33 5.00
92 INT112287 Gene_expression of SLCO1B1 3 0.75 0.09 0.32 5.00
93 INT190692 Positive_regulation of Binding of GGT1 1 0.49 1.38 0.3 5.00
94 INT189833 Negative_regulation of Phosphorylation of Stat1 4 0.51 1.1 0.3 5.00
95 INT199557 Positive_regulation of Gene_expression of Bcr 6 0.68 4.21 0.3 5.00
96 INT241498 Regulation of Abl1 8 0.32 6.46 0.22 5.00
97 INT85595 Positive_regulation of CYP2A6 5 0.67 1.02 0.17 5.00
98 INT347214 Positive_regulation of Negative_regulation of Bcr 1 0.38 1.43 0.17 5.00
99 INT199561 Positive_regulation of Gene_expression of Abl1 8 0.36 4.77 0.16 5.00
100 INT181787 Transcription of ERBB2 13 0.71 10.03 0.16 5.00
101 INT190023 Negative_regulation of Mrc1 15 0.25 12.36 0.16 5.00
102 INT156610 Negative_regulation of HBB 2 0.37 1.25 0.15 5.00
103 INT273560 Negative_regulation of Crkl 2 0.22 2.5 0.14 5.00
104 INT112993 Binding of Mrc1 7 0.21 6.55 0.12 5.00
105 INT183206 Regulation of UTS2R 5 0.13 3.17 0.12 5.00
106 INT190693 Negative_regulation of Regulation of APOA1 1 0.09 1.94 0.11 5.00
107 INT320145 Negative_regulation of Phosphorylation of Bcr 2 0.35 0.23 0.11 5.00
108 INT320147 Phosphorylation of Bcr 2 0.67 0.64 0.11 5.00
109 INT74442 Binding of ATRX 2 0.41 3.2 0.09 5.00
110 INT223082 Regulation of Pdgfrb 3 0.25 2.14 0.08 5.00
111 INT347217 Negative_regulation of Gene_expression of Bcr 1 0.35 0.17 0.08 5.00
112 INT128794 Negative_regulation of Gene_expression of HBB 1 0.59 5.98 0.06 5.00
113 INT241507 Positive_regulation of Abl1 5 0.40 2.69 0.05 5.00
114 INT241510 Negative_regulation of Phosphorylation of Kit 3 0.31 2.06 0.03 5.00
115 INT178963 Gene_expression of Evpl 2 0.42 0.65 0 5.00
116 INT200803 Phosphorylation of Stat5a 2 0.59 1.23 0 5.00
117 INT207239 Binding of HBE1 2 0.20 1.53 0 5.00
118 INT318137 Negative_regulation of PMCH 1 0.02 0.96 0 5.00
119 INT223289 Negative_regulation of H6PD 1 0.24 0.55 0 5.00
120 INT203873 Phosphorylation of NAT2 2 0.81 0.69 0 5.00
121 INT223290 Binding of VKORC1 1 0.39 0.16 0 5.00
122 INT223291 Regulation of Transcription of ERBB2 1 0.25 0.21 0 5.00
123 INT318136 Positive_regulation of Gene_expression of HBB 1 0.04 2.65 0 5.00
124 INT223292 Localization of SLC22A3 1 0.29 0.06 0 5.00
125 INT174724 Regulation of Transcription of ESR1 2 0.18 0.49 0 5.00
126 INT223293 Localization of SLC22A1 1 0.30 0.06 0 5.00
127 INT223294 Localization of POU2F2 1 0.33 0.06 0 5.00
128 INT202203 Positive_regulation of GSTT1 4 0.47 1.26 0 5.00
129 INT285208 Gene_expression of Slc22a1 2 0.65 0.08 0 5.00
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