D:Glandular And Epithelial Neoplasms

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Disease Term
Synonyms Epithelial Neoplasm, EPITHELIAL NEOPLASM GLANDULAR, Epithelial Neoplasms, Epithelial Neoplasms Glandular, Glandular Epithelial Neoplasm, Glandular Epithelial Neoplasms, Glandular Neoplasm, GLANDULAR NEOPLASMS, Neoplasm Epithelial, Neoplasm Glandular, Neoplasm Glandular Epithelial
Documents 54
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glandular And Epithelial Neoplasms. They are ordered first by their relevance to Glandular And Epithelial Neoplasms and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 43.12
2 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
3 INT183645 Ppp1r14b Positive_regulation of Macf1 1 0.00 1.23 0.38 5.00
4 INT183647 Dss1 Positive_regulation of Macf1 1 0.01 1.23 0.38 5.00
5 INT183646 Negative_regulation of Ppp1r14b Positive_regulation of Macf1 1 0.00 1.29 0.38 5.00
6 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22 5.00
7 INT183644 Nos2 Positive_regulation of Gene_expression of Macf1 1 0.05 0.84 0.21 5.00
8 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2 5.00
9 INT291346 IL8 Positive_regulation of Binding of EGFR and GRB2 1 0.15 1.17 0.2 5.00
10 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 5.00
11 INT291347 Positive_regulation of TXK Positive_regulation of CXCR4 Positive_regulation of EPHB2 1 0.02 0.61 0.13 5.00
12 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 5.00
13 INT291353 IL8 Positive_regulation of Binding of EGFR 1 0.32 0.52 0.1 5.00
14 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1 5.00
15 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1 5.00
16 INT291350 IL8 Positive_regulation of Phosphorylation of EGFR 1 0.32 0.52 0.1 5.00
17 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09 5.00
18 INT291355 CXCL12 Positive_regulation of Gene_expression of HGF 1 0.06 1.53 0.06 5.00
19 INT291356 CXCL12 Positive_regulation of AKT1 1 0.04 1.28 0.03 5.00
20 INT291357 CXCR4 Positive_regulation of AKT1 1 0.08 1.27 0.03 5.00
21 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
22 INT304020 AR Regulation of TP53 1 0.24 1.11 0 5.00
23 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0 5.00
24 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 5.00
25 INT183648 Binding of Lef1 and Ctnnd2 1 0.07 1.05 0 5.00
26 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 5.00
27 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 5.00
28 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 5.00
29 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 5.00
30 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
31 INT183649 Binding of Ctnnd2 and Gtf3a 1 0.02 1.05 0 5.00
32 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
33 INT282743 Hsp90aa1 Positive_regulation of Kit 1 0.22 0.54 0 5.00
34 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 5.00
35 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
36 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 5.00
37 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 5.00
38 INT300631 Binding of TSC1 and TSC2 1 0.15 2.59 0 5.00
39 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
40 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 5.00
41 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00
42 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glandular And Epithelial Neoplasms. They are ordered first by their pain relevance and then by number of times they were reported in Glandular And Epithelial Neoplasms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 94.16
2 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 94.16
3 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 93.44
4 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 93.08
5 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 83.64
6 INT124185 Negative_regulation of Kit 57 0.59 35.43 3.61 83.00
7 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 78.56
8 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 75.00
9 INT22707 Positive_regulation of Eno2 36 0.69 27.31 5.07 75.00
10 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 75.00
11 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 75.00
12 INT15752 Positive_regulation of Ema 15 0.40 14.57 2.34 75.00
13 INT113111 Regulation of CXCR4 14 0.61 12.81 1.39 68.04
14 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48 68.04
15 INT291373 Regulation of CXCR7 1 0.30 0.89 0 68.04
16 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 67.20
17 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 67.20
18 INT183629 Gene_expression of Ctnnd2 14 0.75 11.78 0.48 65.88
19 INT121661 Binding of CXCL12 25 0.37 11.27 3.82 65.68
20 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 56.80
21 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 53.16
22 INT201858 Gene_expression of SFRP4 3 0.48 4.91 0.51 48.68
23 INT304048 Negative_regulation of Gene_expression of SFRP4 1 0.34 0.97 0 48.68
24 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 46.48
25 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 42.84
26 INT304052 Binding of MSI1 8 0.05 12.19 0 41.76
27 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 38.80
28 INT122038 Transcription of Ppara 35 0.71 20.5 5.12 36.04
29 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 35.64
30 INT15888 Positive_regulation of Nbr1 42 0.69 35.76 10.48 35.64
31 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 35.64
32 INT121659 Positive_regulation of CXCL12 8 0.53 9.17 2.36 34.32
33 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 12.40
34 INT18897 Binding of CHGA 11 0.36 10.12 1.17 12.40
35 INT6557 Gene_expression of Eno2 65 0.77 54.42 8.17 11.28
36 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
37 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
38 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
39 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 5.00
40 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 5.00
41 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
42 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
43 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 5.00
44 INT6490 Negative_regulation of ADCY1 145 0.58 26.25 70.96 5.00
45 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
46 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
47 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
48 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
49 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
50 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 5.00
51 INT122041 Binding of Ppara 308 0.48 189.17 51.48 5.00
52 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
53 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
54 INT88322 Gene_expression of CCR5 111 0.78 77.36 39.84 5.00
55 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 5.00
56 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 5.00
57 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 5.00
58 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
59 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82 5.00
60 INT88318 Gene_expression of CXCR4 208 0.77 189.67 31.72 5.00
61 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
62 INT121663 Gene_expression of CXCR3 76 0.77 50.96 30.62 5.00
63 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
64 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 5.00
65 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
66 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
67 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
68 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
69 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 5.00
70 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
71 INT122570 Negative_regulation of Akt1 173 0.59 91.44 25.53 5.00
72 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 5.00
73 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 5.00
74 INT11157 Binding of EGF 88 0.48 53.73 21.25 5.00
75 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 5.00
76 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 5.00
77 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 5.00
78 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
79 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 5.00
80 INT78990 Regulation of Cpox 72 0.57 35.22 18.16 5.00
81 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
82 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
83 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
84 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
85 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 5.00
86 INT20420 Gene_expression of MYC 99 0.75 49.32 14.36 5.00
87 INT37722 Gene_expression of NCAM1 103 0.75 81.57 14.18 5.00
88 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 5.00
89 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 5.00
90 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 5.00
91 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
92 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 5.00
93 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 5.00
94 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
95 INT137181 Gene_expression of CXCL9 25 0.65 13.09 9.56 5.00
96 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
97 INT119831 Gene_expression of PTEN 55 0.75 40.37 8.57 5.00
98 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 5.00
99 INT87650 Positive_regulation of EPHB2 49 0.67 22.77 8.25 5.00
100 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 5.00
101 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21 5.00
102 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
103 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 5.00
104 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72 5.00
105 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56 5.00
106 INT116717 Gene_expression of CCR7 37 0.76 34.1 7.48 5.00
107 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 5.00
108 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 5.00
109 INT82610 Positive_regulation of SRC 53 0.67 26.89 7.27 5.00
110 INT125143 Gene_expression of EPHB2 40 0.71 13.27 6.97 5.00
111 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84 5.00
112 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84 5.00
113 INT11154 Binding of EGFR 149 0.48 96.23 6.29 5.00
114 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
115 INT113112 Negative_regulation of CXCR4 39 0.58 28.28 5.36 5.00
116 INT6476 Gene_expression of TNFRSF1B 21 0.67 18.22 5.25 5.00
117 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 5.00
118 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 5.00
119 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
120 INT105336 Regulation of AKT1 52 0.56 32.53 4.89 5.00
121 INT10115 Gene_expression of INSR 31 0.75 11.98 4.86 5.00
122 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
123 INT47451 Positive_regulation of Positive_regulation of ras 18 0.35 10.07 4.6 5.00
124 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 5.00
125 INT109450 Positive_regulation of Phosphorylation of AKT1 62 0.64 25.18 4.21 5.00
126 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15 5.00
127 INT91327 Positive_regulation of CCL4 12 0.67 8.55 4.1 5.00
128 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 5.00
129 INT133641 Binding of CCL28 5 0.47 3.23 3.71 5.00
130 INT64766 Gene_expression of TWIST1 41 0.76 37.89 3.4 5.00
131 INT84409 Binding of TNS1 6 0.48 2.96 3.33 5.00
132 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
133 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 5.00
134 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 5.00
135 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
136 INT103674 Positive_regulation of Gene_expression of CXCR4 32 0.69 37.1 3.08 5.00
137 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 5.00
138 INT192676 Binding of PTEN 14 0.46 10.58 3.06 5.00
139 INT89392 Negative_regulation of Positive_regulation of AKT1 23 0.50 15.69 3.02 5.00
140 INT200670 Gene_expression of AKT2 25 0.75 16.25 3 5.00
141 INT89397 Positive_regulation of PIK3CA 33 0.67 16.98 2.78 5.00
142 INT74293 Positive_regulation of BAK1 13 0.60 14.13 2.73 5.00
143 INT157461 Binding of CX3CR1 3 0.36 6.72 2.67 5.00
144 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 5.00
145 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
146 INT108482 Positive_regulation of Gene_expression of CXCL12 7 0.53 9.72 2.36 5.00
147 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 5.00
148 INT50558 Negative_regulation of PCNA 31 0.57 13.97 2.3 5.00
149 INT151449 Negative_regulation of Gene_expression of Kit 18 0.45 12.05 2.23 5.00
150 INT179885 Regulation of PTEN 8 0.26 11.88 2.18 5.00
151 INT38674 Regulation of KRT20 32 0.44 19 2.15 5.00
152 INT67190 Gene_expression of Muc2 24 0.78 18.8 2.08 5.00
153 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 5.00
154 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98 5.00
155 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 5.00
156 INT99572 Localization of Kit 13 0.75 5.23 1.95 5.00
157 INT20421 Positive_regulation of MYC 19 0.67 10.43 1.9 5.00
158 INT36018 Negative_regulation of Gene_expression of CD8A 12 0.42 6.66 1.85 5.00
159 INT111575 Gene_expression of Muc5ac 15 0.78 7.97 1.84 5.00
160 INT123130 Positive_regulation of Positive_regulation of AKT1 22 0.49 11.77 1.83 5.00
161 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 5.00
162 INT86909 Negative_regulation of MSH2 9 0.41 12.65 1.7 5.00
163 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 5.00
164 INT113110 Negative_regulation of CXCL12 8 0.43 6.01 1.63 5.00
165 INT15692 Regulation of HTC2 4 0.27 4.75 1.61 5.00
166 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 5.00
167 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55 5.00
168 INT52962 Binding of ERBB2 77 0.47 50.03 1.49 5.00
169 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 5.00
170 INT304045 Transcription of PTEN 2 0.51 4.12 1.4 5.00
171 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38 5.00
172 INT96993 Positive_regulation of Phosphorylation of EGFR 15 0.59 5.44 1.37 5.00
173 INT12370 Gene_expression of TNS1 6 0.67 1.7 1.37 5.00
174 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 5.00
175 INT214073 Binding of TSC1 9 0.37 22 1.34 5.00
176 INT92383 Gene_expression of KRAS 38 0.65 32.94 1.32 5.00
177 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 5.00
178 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 5.00
179 INT245089 Localization of CXCL12 8 0.65 10.17 1.28 5.00
180 INT183636 Binding of Dss1 5 0.34 2.61 1.27 5.00
181 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
182 INT210399 Gene_expression of IGF2R 22 0.65 17.1 1.23 5.00
183 INT10117 Positive_regulation of INSR 10 0.43 4.71 1.22 5.00
184 INT183635 Negative_regulation of Positive_regulation of Ppara 11 0.42 10 1.2 5.00
185 INT119832 Positive_regulation of Gene_expression of PTEN 12 0.49 7.12 1.19 5.00
186 INT135556 Localization of AKT1 38 0.69 12.78 1.17 5.00
187 INT220206 Gene_expression of CCNB2 4 0.67 3.75 1.16 5.00
188 INT146546 Gene_expression of MSI1 22 0.48 22.91 1.15 5.00
189 INT193815 Regulation of Gene_expression of CXCR4 17 0.61 20.27 1.15 5.00
190 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15 5.00
191 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 5.00
192 INT291359 Binding of Cx3cl1 2 0.36 2.31 1.13 5.00
193 INT86908 Negative_regulation of MLH1 7 0.43 6.98 1.12 5.00
194 INT150 Negative_regulation of CXCL11 4 0.57 3.34 1.12 5.00
195 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
196 INT291366 Binding of CXCR7 4 0.18 1.64 1.03 5.00
197 INT177615 Gene_expression of PAX7 20 0.65 13.5 1.03 5.00
198 INT92139 Binding of MLH1 12 0.42 15.62 1 5.00
199 INT187153 Negative_regulation of Gene_expression of CXCR3 3 0.36 2.25 0.98 5.00
200 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 5.00
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