D:Glaucoma

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Disease Term
Synonyms Angla Closure Glaucoma, Angle Closure Glaucoma, Axenfeld Reiger Syndrome, AXENFELD RIEGER SYNDROME, Ciliary Block Glaucoma, Combined Mechanism Glaucoma, Congenital Glaucoma, Developmental Glaucoma, Glaucoma Ocular Hypertension, GLAUCOMAS, High Pressure Glaucoma
Documents 1420
Hot Single Events 200
Hot Interactions 64

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glaucoma. They are ordered first by their relevance to Glaucoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04 100.00
2 INT302511 Binding of OPA1 and Nos3 1 0.02 1.57 0.1 100.00
3 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 99.92
4 INT170562 Car2 Regulation of Narf 1 0.05 1.17 0 99.88
5 INT275667 Binding of CYP1B1 and GLC3C 1 0.27 0.99 0 99.76
6 INT287374 Binding of SNRNP70 and rs 1 0.03 1.7 0 99.60
7 INT294412 Binding of Vav2 and Vav3 1 0.41 0.65 0 99.60
8 INT302507 Binding of GLC1F and OPA1 1 0.01 3.76 0 99.36
9 INT245722 Binding of Vsx2 and Mfrp 1 0.24 1.2 0 98.88
10 INT262817 Serpinf1 Regulation of Positive_regulation of 1190002H23Rik 1 0.06 1.3 0.22 98.80
11 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 98.76
12 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 98.76
13 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 98.76
14 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03 98.64
15 INT314868 Binding of Ltbp2 and Ltbp3 1 0.29 0.54 0 98.44
16 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0 98.24
17 INT170558 Binding of Myoc and Narf 1 0.04 3.03 0.63 98.04
18 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04 97.84
19 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27 97.44
20 INT96833 Binding of WAS and Positive_regulation of Cnr1 1 0.02 0.69 0.39 97.44
21 INT96834 Binding of WAS and Positive_regulation of Cnr2 1 0.03 0.69 0.39 97.44
22 INT96836 WAS Positive_regulation of Cnr1 1 0.02 0.69 0.39 97.44
23 INT96835 WAS Positive_regulation of Cnr2 1 0.03 0.69 0.39 97.44
24 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04 97.32
25 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0 97.00
26 INT251349 Ifnar1 Positive_regulation of Rock1 1 0.01 1.27 0.16 96.72
27 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16 95.80
28 INT294413 Proc Positive_regulation of Cdc42ep3 1 0.00 0.78 0 95.68
29 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 95.40
30 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 95.40
31 INT138515 Drd3 Negative_regulation of Localization of Tnf 1 0.06 0.4 0.36 94.92
32 INT267118 Lmx1b Regulation of Regulation of Col7a1 1 0.06 0.47 0 93.84
33 INT249332 GPNMB Positive_regulation of EGFR 1 0.17 2.63 0.08 92.40
34 INT278441 Lbp Positive_regulation of Gene_expression of ITGAX 1 0.44 1.18 0.07 92.24
35 INT249324 GPNMB Positive_regulation of GPNMB Positive_regulation of EGFR 1 0.12 1.31 0.04 91.92
36 INT262818 Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.45 0.71 0.18 91.92
37 INT261981 EP400 Negative_regulation of CYP1B1 1 0.01 0.22 0 91.92
38 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 91.36
39 INT259716 Loxl1 Regulation of Loxl1 1 0.00 1.84 0.08 90.84
40 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0 90.72
41 INT314851 Positive_regulation of Binding of Neurod1 and Atoh7 1 0.23 0.27 0 90.72
42 INT314860 Gene_expression of Atoh7 Positive_regulation of 1190002H23Rik 1 0.02 0.27 0 90.72
43 INT314864 Binding of Neurod1 and Positive_regulation of Gene_expression of Atoh7 1 0.25 0.27 0 90.72
44 INT251348 Ifnar1 Positive_regulation of Limk2 1 0.01 1.12 0.11 90.64
45 INT314863 Binding of Neurod1 and Atoh7 1 0.18 0.27 0 90.00
46 INT228005 Binding of Eln and Loxl1 1 0.35 1.58 0 88.56
47 INT228006 Positive_regulation of Binding of Eln and Loxl1 1 0.37 0.55 0 88.56
48 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 88.36
49 INT287371 SNRNP70 Regulation of Gene_expression of Loxl1 1 0.01 0.9 0 88.16
50 INT228002 Binding of Loxl1 and Fbln5 1 0.34 1.57 0 88.16
51 INT228004 Positive_regulation of Binding of Loxl1 and Fbln5 1 0.35 0.54 0 88.16
52 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0 87.68
53 INT99842 Edn1 Negative_regulation of Localization of Ren 1 0.24 0.43 0.32 87.40
54 INT99843 Edn3 Negative_regulation of Localization of Ren 1 0.25 0.42 0.31 87.40
55 INT314870 Binding of Ltbp3 and Tgfb3 1 0.24 0.52 0 86.80
56 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0 85.92
57 INT111839 Binding of Cnr1 and Cnr2 1 0.05 0.53 0.6 85.88
58 INT314865 Binding of Ltbp3 and Tgfb1 1 0.24 0.51 0 85.36
59 INT314861 Gdf11 Regulation of Gene_expression of Atoh7 1 0.20 0.26 0 85.04
60 INT262825 Serpinf1 Negative_regulation of Gfap 1 0.34 0.87 0.08 84.32
61 INT273772 BCKDHA Positive_regulation of Positive_regulation of NARFL 1 0.03 1.21 0 83.64
62 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08 82.40
63 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 81.60
64 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0 81.60
65 INT267119 Lmx1b Regulation of Regulation of Col4a1 1 0.09 0.67 0 79.76
66 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 79.28
67 INT255660 Coq10a Negative_regulation of Rgc32 1 0.02 1.11 0.13 78.48
68 INT111840 Binding of Cnr1 and sar 1 0.04 0.45 0.52 78.48
69 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0 78.32
70 INT247889 Positive_regulation of Narfl Positive_regulation of CASP3 1 0.00 0.84 0 78.32
71 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 78.24
72 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 77.84
73 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 76.28
74 INT274096 Binding of EDN1 and EDNRA Positive_regulation of Positive_regulation of EDN1 1 0.22 0.78 0 74.64
75 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0 74.44
76 INT340439 Binding of HLA-DMA and SUGT1 1 0.00 4.1 1.16 72.68
77 INT340438 Binding of HLA-DMA and MRAP 1 0.02 1.69 0.43 72.68
78 INT255659 Binding of Anxa5 and Ca2 1 0.02 1.23 0.04 72.44
79 INT314850 Shh Regulation of Atoh7 1 0.45 0.22 0 71.68
80 INT314854 Gdf11 Regulation of Atoh7 1 0.51 0.21 0 71.36
81 INT314857 Atoh7 Regulation of Pou4f2 1 0.21 0.21 0 70.76
82 INT284705 CMA1 Positive_regulation of Gene_expression of COL7A1 1 0.04 0.49 0.05 70.16
83 INT170559 Narf Regulation of Gene_expression of Car2 1 0.05 1.01 0 69.88
84 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0 67.40
85 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37 66.72
86 INT255658 Coq10a Regulation of Negative_regulation of Rgc32 1 0.01 1.14 0.14 65.68
87 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 65.20
88 INT268710 Binding of RHO and ERLEC1 1 0.00 0.71 0.03 65.20
89 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0 63.84
90 INT287372 Binding of SNRNP70 and Loxl1 1 0.02 0.38 0 63.04
91 INT287373 Positive_regulation of Binding of SNRNP70 and Loxl1 1 0.02 0.19 0 63.04
92 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 60.56
93 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 58.96
94 INT314866 Binding of Six1 and Sall1 1 0.39 0.76 0 57.68
95 INT347577 Binding of MUC1 and MUC16 1 0.25 0.42 0 57.44
96 INT278438 Lbp Positive_regulation of Il2 1 0.12 0.89 0 56.16
97 INT211492 Positive_regulation of GRIN1 Positive_regulation of Prkca 1 0.01 0.87 0.36 56.00
98 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05 55.36
99 INT279620 Negative_regulation of Binding of Grin2a and Grin2b 1 0.18 0.99 0.4 54.00
100 INT212290 Binding of Grin2a and Grin2b 2 0.20 1.36 0.82 52.32
101 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2 52.24
102 INT260496 Hif1a Regulation of Gene_expression of VEGFA 1 0.12 0.93 0 51.20
103 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03 50.16
104 INT247853 Positive_regulation of Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 0.54 0 50.16
105 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04 50.00
106 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03 47.72
107 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 47.08
108 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0 43.36
109 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03 42.96
110 INT247857 Narfl Positive_regulation of Gene_expression of Gfap 1 0.07 0.81 0 42.64
111 INT299234 Onc1 Negative_regulation of Thy1 1 0.02 0.16 0 40.32
112 INT287381 Cxcl2 Regulation of Gene_expression of VEGFA 1 0.42 1.1 0.1 38.20
113 INT314853 Binding of Cdc7 and Tgfbr3 1 0.24 0.09 0 32.48
114 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0 29.68
115 INT337918 sb Positive_regulation of Negative_regulation of Smad2 1 0.00 0.15 0 29.04
116 INT170561 Renbp Regulation of Narf 1 0.01 3.86 0 28.80
117 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03 26.72
118 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 23.40
119 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 21.08
120 INT339581 Binding of TIMP1 and TIMP3 1 0.30 0.54 0 20.40
121 INT340437 Binding of SERPINH1 and HLA-DRB4 1 0.00 2.26 0.84 19.60
122 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0 17.44
123 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0 17.44
124 INT299233 Onc1 Regulation of Gene_expression of Aqp9 1 0.01 0.19 0 16.76
125 INT314855 Binding of Gdf11 and Atoh7 1 0.40 0.14 0 15.96
126 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43 12.56
127 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0 11.36
128 INT314858 Binding of Gdf11 and Ltbp3 1 0.39 0.31 0 9.24
129 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 7.20
130 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 7.20
131 INT339580 TIMP3 Positive_regulation of ABCA1 1 0.16 0.73 0 6.56
132 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03 5.76
133 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
134 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
135 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
136 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
137 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
138 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16 5.00
139 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
140 INT269191 Binding of Grin1 and Grin3a 2 0.32 1.05 1.09 5.00
141 INT269189 Binding of Grin2a and Grin3a 2 0.25 1.05 1.09 5.00
142 INT323278 Dhfr Negative_regulation of Negative_regulation of Igkv1-131 1 0.02 0.93 1.02 5.00
143 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 5.00
144 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 5.00
145 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91 5.00
146 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79 5.00
147 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78 5.00
148 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77 5.00
149 INT210984 Cfp Positive_regulation of Positive_regulation of Dio1 1 0.07 0.81 0.75 5.00
150 INT210979 Grm5 Positive_regulation of Cysltr1 1 0.00 0.76 0.75 5.00
151 INT210980 Cysltr1 Positive_regulation of Positive_regulation of Dio1 1 0.00 0.81 0.75 5.00
152 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73 5.00
153 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73 5.00
154 INT210981 Calb1 Positive_regulation of Cysltr1 1 0.00 0.81 0.69 5.00
155 INT210985 Positive_regulation of Calb1 Positive_regulation of Cysltr1 1 0.00 0.81 0.69 5.00
156 INT210983 Calb1 Positive_regulation of Cnr1 1 0.01 0.81 0.68 5.00
157 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 5.00
158 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
159 INT254761 Igh-Dex Positive_regulation of Apoe 1 0.00 0.08 0.52 5.00
160 INT323280 Dhfr Negative_regulation of Igkv1-131 1 0.02 0.47 0.51 5.00
161 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5 5.00
162 INT254768 DNMT1 Positive_regulation of Gene_expression of Apoe 1 0.02 0.05 0.49 5.00
163 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
164 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48 5.00
165 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48 5.00
166 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
167 INT340440 Binding of HLA-B and BTG3 1 0.05 1.57 0.47 5.00
168 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
169 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
170 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
171 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42 5.00
172 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42 5.00
173 INT254760 Igh-Dex Positive_regulation of Gene_expression of Apoe 1 0.00 0 0.42 5.00
174 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
175 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37 5.00
176 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34 5.00
177 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34 5.00
178 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
179 INT254759 Igh-Dex Positive_regulation of Localization of Apoe 1 0.00 0.32 0.28 5.00
180 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28 5.00
181 INT262354 TRIP10 Negative_regulation of Cyp4a3 1 0.00 0.8 0.26 5.00
182 INT262353 TRIP10 Negative_regulation of Cyp1a2 1 0.03 0.8 0.26 5.00
183 INT262329 TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
184 INT262330 Positive_regulation of TRIP10 Negative_regulation of CYP2C19 1 0.01 0.8 0.26 5.00
185 INT254772 DNMT1 Positive_regulation of Apoe 1 0.02 0 0.25 5.00
186 INT254773 PPARA Positive_regulation of Gene_expression of Apoe 1 0.01 0.07 0.24 5.00
187 INT254774 DNMT1 Positive_regulation of Localization of Apoe 1 0.01 0.31 0.23 5.00
188 INT254770 Regulation of Binding of DNMT1 and Igh-Dex 1 0.00 0 0.22 5.00
189 INT241451 Mag Positive_regulation of Ngfr 1 0.09 0.1 0.21 5.00
190 INT274080 Binding of ARHGAP4 and Map3k5 1 0.41 1.92 0.2 5.00
191 INT181646 interleukin-17 Positive_regulation of ISYNA1 1 0.01 0.26 0.2 5.00
192 INT181617 IL17A Positive_regulation of ISYNA1 1 0.01 0.27 0.2 5.00
193 INT254771 Binding of DNMT1 and Igh-Dex 1 0.00 0 0.19 5.00
194 INT210978 THL Negative_regulation of Cysltr1 1 0.01 0.27 0.18 5.00
195 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18 5.00
196 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17 5.00
197 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17 5.00
198 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17 5.00
199 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17 5.00
200 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glaucoma. They are ordered first by their pain relevance and then by number of times they were reported in Glaucoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140896 Gene_expression of GPNMB 9 0.51 7.38 0.4 100.00
2 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 100.00
3 INT249339 Gene_expression of MBNL1 4 0.17 3.64 0.53 100.00
4 INT308240 Gene_expression of Prm3 1 0.06 3.69 0.09 100.00
5 INT249344 Positive_regulation of MBNL1 1 0.01 2.88 0 100.00
6 INT165773 Gene_expression of Darc 37 0.75 22.28 14.84 100.00
7 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84 100.00
8 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
9 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19 100.00
10 INT274270 Negative_regulation of Transcription of MRXS5 1 0.35 1.76 0.09 100.00
11 INT34976 Positive_regulation of Gene_expression of OPA1 4 0.43 4.21 0.4 100.00
12 INT329019 Negative_regulation of Binding of SRGN 1 0.28 1.22 0.03 100.00
13 INT329018 Binding of SRGN 1 0.23 1.21 0.03 100.00
14 INT329016 Regulation of Gene_expression of GON4L 1 0.06 1.12 0.05 100.00
15 INT329020 Regulation of GON4L 1 0.06 1.12 0.05 100.00
16 INT242208 Regulation of Gene_expression of SRGN 7 0.29 3.15 0.52 100.00
17 INT177342 Negative_regulation of SRGN 15 0.28 5.66 0.04 100.00
18 INT189479 Positive_regulation of Gene_expression of Darc 5 0.31 3.06 1.17 100.00
19 INT308238 Binding of Prm3 2 0.05 1.3 0.2 100.00
20 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 100.00
21 INT308239 Negative_regulation of Gene_expression of Prm3 1 0.04 1.12 0 100.00
22 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55 100.00
23 INT287367 Regulation of Binding of SNRNP70 2 0.44 1.01 0 100.00
24 INT287355 Regulation of Binding of Loxl1 1 0.44 1.01 0 100.00
25 INT202940 Binding of AMD1 13 0.41 16.43 0.56 100.00
26 INT54807 Binding of MLLT1 4 0.11 2.96 0.22 100.00
27 INT202939 Regulation of AMD1 4 0.38 2.68 0 100.00
28 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 99.98
29 INT80809 Gene_expression of STMN1 8 0.28 6.71 0.99 99.96
30 INT227780 Gene_expression of GON4L 2 0.13 2.72 0.05 99.96
31 INT249337 Positive_regulation of Gene_expression of STMN1 1 0.22 0.99 0 99.96
32 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 99.92
33 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78 99.92
34 INT260527 Negative_regulation of AMD1 6 0.37 5 0.05 99.92
35 INT289992 Phosphorylation of Cntf 1 0.30 1 0.22 99.92
36 INT269748 Positive_regulation of AMD1 4 0.43 3.56 0.28 99.92
37 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 99.90
38 INT69784 Binding of MYOC 8 0.48 5.67 0.21 99.88
39 INT255654 Binding of Rgc32 1 0.04 1.34 0.06 99.88
40 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 99.88
41 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 99.86
42 INT96885 Localization of CYP1B1 4 0.80 2.11 0.23 99.86
43 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 99.84
44 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 99.84
45 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 99.84
46 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 99.84
47 INT181642 Negative_regulation of Narf 2 0.01 28.07 4.01 99.84
48 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 99.84
49 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 99.84
50 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 99.84
51 INT274271 Negative_regulation of Negative_regulation of NARFL 1 0.06 5.13 0.22 99.84
52 INT239753 Gene_expression of MFRP 1 0.64 3 0 99.84
53 INT239757 Gene_expression of VSX2 1 0.61 3 0 99.84
54 INT54072 Gene_expression of GAP43 14 0.67 5.04 2.83 99.84
55 INT274098 Regulation of EDNRB 1 0.33 2.41 0.18 99.84
56 INT239755 Regulation of Gene_expression of MFRP 1 0.43 1.53 0 99.84
57 INT239758 Regulation of Gene_expression of VSX2 1 0.41 1.53 0 99.84
58 INT55139 Positive_regulation of STMN1 2 0.49 1.06 0 99.84
59 INT22335 Regulation of Negative_regulation of ACE 10 0.44 7.01 1.77 99.84
60 INT255652 Binding of Coq10a 1 0.08 1.04 0 99.84
61 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.84
62 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 99.84
63 INT284712 Positive_regulation of CMA1 1 0.59 0.32 0 99.84
64 INT168188 Gene_expression of PLXNA2 13 0.58 9 2.73 99.82
65 INT112267 Positive_regulation of Rgc32 10 0.39 8.1 2.09 99.82
66 INT255655 Positive_regulation of Gene_expression of Rgc32 1 0.06 2.26 0.04 99.82
67 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.82
68 INT276227 Gene_expression of UBL4A 9 0.20 7.12 0.64 99.82
69 INT170547 Positive_regulation of Narf 29 0.06 64.48 1.61 99.80
70 INT96873 Gene_expression of CYP1B1 28 0.78 11.81 1.09 99.80
71 INT93350 Binding of Lepr 17 0.05 27.21 1.5 99.80
72 INT249336 Positive_regulation of GPNMB 1 0.46 5.96 0.05 99.80
73 INT272272 Positive_regulation of Gene_expression of NARFL 17 0.40 18.85 0.31 99.80
74 INT170550 Binding of Narf 9 0.04 14.89 1.18 99.80
75 INT302503 Binding of Agap3 1 0.19 0.8 0 99.80
76 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 99.78
77 INT274269 Transcription of NARFL 1 0.09 1.13 0.03 99.78
78 INT274274 Positive_regulation of Transcription of NARFL 1 0.06 1.13 0.03 99.78
79 INT294398 Gene_expression of Vav2 1 0.78 10.67 0.06 99.76
80 INT270629 Gene_expression of Vav3 3 0.78 9.71 0.06 99.76
81 INT311605 Positive_regulation of AATF 5 0.06 6.72 1.05 99.76
82 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 99.72
83 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 99.68
84 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 99.68
85 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 99.68
86 INT30851 Gene_expression of NRG1 8 0.67 4.64 1.12 99.68
87 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 99.66
88 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 99.66
89 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.66
90 INT170553 Negative_regulation of Narf 12 0.05 16.19 3.78 99.64
91 INT247868 Positive_regulation of Narfl 1 0.11 37.11 0.68 99.62
92 INT249914 Positive_regulation of Epas1 2 0.19 2.42 0.05 99.62
93 INT69782 Gene_expression of MYOC 12 0.78 8.44 0.61 99.60
94 INT294402 Binding of Vav3 1 0.48 2.43 0 99.60
95 INT274273 Regulation of Gene_expression of NARFL 3 0.10 4.39 0.2 99.60
96 INT287041 Binding of Vav1 6 0.37 3.4 0 99.60
97 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 99.60
98 INT146505 Positive_regulation of Regulation of Gfap 4 0.44 1.98 0.7 99.60
99 INT15002 Regulation of Gfap 17 0.37 5.34 3.61 99.60
100 INT213431 Positive_regulation of Gene_expression of MMRN1 15 0.24 9.91 1.96 99.60
101 INT114882 Positive_regulation of Gene_expression of Akt1 45 0.69 21.29 6.06 99.60
102 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 99.60
103 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 99.58
104 INT208140 Localization of PITX1 2 0.73 6.18 0.14 99.58
105 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.56
106 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.56
107 INT219219 Gene_expression of Rgc32 9 0.13 7.29 0.85 99.56
108 INT103803 Positive_regulation of Gene_expression of CAPG 2 0.34 1.43 0.37 99.56
109 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 99.56
110 INT227782 Gene_expression of IZUMO1 1 0.22 6.38 0.65 99.54
111 INT245719 Binding of Epyc 1 0.10 0.83 0 99.52
112 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 99.50
113 INT10132 Negative_regulation of Serpinf1 14 0.58 11.72 3.14 99.48
114 INT262004 Negative_regulation of CYP1B1 4 0.59 3.24 0 99.48
115 INT274272 Transcription of MRXS5 1 0.57 1.75 0.09 99.48
116 INT114472 Regulation of Izumo1 13 0.48 7.95 3.2 99.46
117 INT39369 Binding of NARFL 14 0.29 16.7 0.93 99.44
118 INT64310 Negative_regulation of GRIN2A 7 0.42 2.16 3.49 99.44
119 INT255656 Transcription of Rgc32 1 0.07 0.76 0.23 99.44
120 INT227989 Binding of Loxl1 3 0.48 2.21 0 99.40
121 INT99965 Positive_regulation of Negative_regulation of NARFL 6 0.40 4.5 0.04 99.40
122 INT26477 Regulation of ACE 26 0.45 16.31 4.33 99.40
123 INT185649 Regulation of ERG 17 0.20 10.14 1.49 99.36
124 INT272274 Localization of NARFL 24 0.60 27.55 1.18 99.32
125 INT170548 Regulation of Narf 1 0.06 34.17 2.18 99.32
126 INT272414 Positive_regulation of Positive_regulation of NARFL 9 0.37 12.88 0.84 99.32
127 INT294396 Regulation of Vav2 1 0.45 1.43 0 99.32
128 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 99.32
129 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 99.32
130 INT314829 Gene_expression of Dclk1 1 0.67 0.66 0 99.32
131 INT50672 Positive_regulation of CPOX 205 0.44 125.93 60.06 99.30
132 INT50673 Positive_regulation of Gene_expression of CPOX 156 0.54 97.31 37.03 99.30
133 INT39941 Negative_regulation of PRLH 1 0.59 1.53 0.17 99.28
134 INT227778 Negative_regulation of IZUMO1 1 0.14 3.86 0.22 99.28
135 INT322937 Negative_regulation of Positive_regulation of NARF 1 0.03 0.94 0 99.28
136 INT322938 Positive_regulation of NARF 1 0.04 0.94 0 99.28
137 INT10131 Gene_expression of Serpinf1 53 0.76 35.57 6.42 99.26
138 INT286249 Regulation of Mfrp 1 0.25 2.14 0.1 99.26
139 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07 99.26
140 INT294395 Binding of Vav2 1 0.48 0.82 0 99.24
141 INT346921 Negative_regulation of NFIC 1 0.11 1.9 0 99.24
142 INT264283 Negative_regulation of Regulation of Izumo1 1 0.01 0.73 0.13 99.24
143 INT227781 Positive_regulation of GON4L 4 0.13 7.56 0.54 99.20
144 INT340784 Positive_regulation of Transcription of TNFRSF1A 1 0.17 0.37 0.13 99.20
145 INT340783 Transcription of TNFRSF1A 1 0.17 0.37 0.13 99.20
146 INT239754 Regulation of VSX2 1 0.48 0.56 0 99.18
147 INT239756 Regulation of Binding of MFRP 1 0.38 0.57 0 99.18
148 INT105021 Binding of GOPC 187 0.40 60.39 20.38 99.18
149 INT116824 Negative_regulation of Rgc32 21 0.31 21.62 2.46 99.16
150 INT95898 Gene_expression of CAPG 14 0.39 10.51 2.33 99.16
151 INT103799 Positive_regulation of CAPG 8 0.34 5.16 1.52 99.16
152 INT284709 Negative_regulation of CMA1 9 0.57 7.06 0.21 99.16
153 INT10485 Regulation of STMN1 3 0.11 1.21 0.94 99.16
154 INT152710 Gene_expression of Dct 3 0.57 0.76 0.17 99.16
155 INT294409 Regulation of Vav3 1 0.45 1.42 0 99.14
156 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 99.12
157 INT173021 Localization of MUC5AC 14 0.70 10.73 0.91 99.12
158 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 99.10
159 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76 99.08
160 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 99.08
161 INT116822 Regulation of Negative_regulation of Rgc32 2 0.20 1.64 0.68 99.08
162 INT101475 Regulation of Gene_expression of Gfap 8 0.62 4.77 1.96 99.08
163 INT233399 Binding of ABCA4 9 0.46 9.49 0.07 99.08
164 INT103260 Positive_regulation of Nps 35 0.48 23.8 5.67 99.08
165 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 99.04
166 INT118124 Binding of USE1 24 0.16 16.64 5.44 99.04
167 INT262003 Binding of CYP1B1 3 0.48 3.34 0 99.00
168 INT228007 Binding of GLC1N 3 0.24 0.74 0.03 99.00
169 INT239759 Binding of MFRP 1 0.31 2.04 0 98.96
170 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 98.92
171 INT272530 Negative_regulation of Localization of NARFL 3 0.09 2.98 0.07 98.92
172 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65 98.92
173 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 98.90
174 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.88
175 INT245715 Binding of Mfrp 1 0.48 3.46 0 98.88
176 INT89549 Positive_regulation of NEFH 2 0.43 1.42 0.86 98.88
177 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 98.88
178 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 98.88
179 INT245717 Binding of Vsx2 2 0.27 1.2 0 98.88
180 INT80037 Gene_expression of BAK1 58 0.75 39.49 9.08 98.84
181 INT148579 Regulation of rs 2 0.15 1.68 0.72 98.84
182 INT3776 Positive_regulation of Regulation of NARFL 2 0.37 2.44 0.93 98.84
183 INT266875 Positive_regulation of Narfl 37 0.05 38.43 3.73 98.80
184 INT3183 Negative_regulation of MRXS5 15 0.41 6.56 3.45 98.80
185 INT190479 Positive_regulation of 1190002H23Rik 6 0.07 5.64 0.53 98.80
186 INT287360 Transcription of Loxl1 1 0.69 5.04 0 98.76
187 INT70297 Gene_expression of NEFH 12 0.75 4.85 2.33 98.76
188 INT287357 Regulation of Transcription of Loxl1 1 0.60 2.69 0 98.76
189 INT27817 Gene_expression of PADI1 5 0.52 1.61 0.17 98.76
190 INT289982 Phosphorylation of CNTF 1 0.79 0.99 0.21 98.76
191 INT262005 Regulation of CYP1B1 4 0.62 4.52 0 98.68
192 INT130560 Negative_regulation of Gene_expression of Serpinf1 17 0.58 13.39 1.94 98.68
193 INT96879 Positive_regulation of CYP1B1 14 0.70 5.73 0.78 98.68
194 INT289498 Negative_regulation of Narfl 4 0.03 3.05 0.31 98.68
195 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 98.68
196 INT239760 Binding of VSX2 1 0.29 1.47 0 98.60
197 INT39942 Positive_regulation of PRLH 1 0.70 0.74 0.07 98.60
198 INT114434 Gene_expression of Calcrl 10 0.78 5.81 1.83 98.56
199 INT286247 Positive_regulation of Gene_expression of Calcrl 1 0.70 2.41 0.07 98.56
200 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 98.56
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