D:Glioblastoma

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Disease Term
Synonyms Astrocytoma Grade Iv, Astrocytomas Grade Iv, GIANT CELL GLIOBLASTOMA, Giant Cell Glioblastomas, Glioblastoma Giant Cell, Glioblastoma Multiforme, GLIOBLASTOMAS, GLIOBLASTOMAS GIANT CELL, Grade Iv Astrocytoma, Grade Iv Astrocytomas
Documents 496
Hot Single Events 200
Hot Interactions 35

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glioblastoma. They are ordered first by their relevance to Glioblastoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04 100.00
2 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04 100.00
3 INT351676 Fut1 Negative_regulation of Ptk2 1 0.01 4.39 0 99.90
4 INT188737 Egfr Positive_regulation of EGFR 1 0.21 0.6 0.04 99.50
5 INT188735 EGFR Positive_regulation of Egfr 1 0.21 0.6 0.04 99.50
6 INT188732 EGFR Positive_regulation of Gene_expression of Egfr 1 0.21 0.6 0.04 99.50
7 INT351678 Nrp1 Regulation of Binding of Ecm1 1 0.00 1.55 0 99.36
8 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 98.88
9 INT321578 Binding of Plaur and Positive_regulation of Ctsb 1 0.15 0.92 0.12 98.80
10 INT128652 ITIH4 Regulation of Gene_expression of CCR5 1 0.36 1.46 0.93 97.48
11 INT128655 ITIH4 Regulation of Gene_expression of CCR3 1 0.36 1.45 0.92 97.12
12 INT351677 Fut1 Negative_regulation of Gene_expression of Ptk2 1 0.01 3.64 0 96.44
13 INT128653 ITIH4 Regulation of Gene_expression of MIP 1 0.23 1.44 0.92 95.96
14 INT128654 ITIH4 Regulation of Gene_expression of CCL16 1 0.02 2.69 1.79 95.80
15 INT351680 Fut1 Regulation of Ptk2 1 0.01 1.68 0 95.60
16 INT166732 BATF Negative_regulation of PPIA 1 0.05 1.45 0.06 94.64
17 INT166734 BATF Negative_regulation of PPIL1 1 0.04 1.45 0.06 94.64
18 INT352620 Gnb5 Positive_regulation of Gene_expression of Myc 1 0.01 1.09 0 93.04
19 INT237921 ROS1 Positive_regulation of TNFRSF10B 1 0.08 1.24 0.03 92.32
20 INT217781 Binding of MITF and TP53 1 0.00 1.2 0 90.08
21 INT217784 Binding of MITF and TSC1 1 0.00 1.21 0 90.08
22 INT279145 Binding of VHL and RNF139 1 0.30 1.87 0 89.84
23 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 88.56
24 INT204080 HP Negative_regulation of Phosphorylation of Rb1 1 0.00 3.53 0.34 87.64
25 INT204071 HP Positive_regulation of Gene_expression of CDKN2A 1 0.00 3.48 0.34 87.64
26 INT351681 Binding of Ecm1 and Fn1 1 0.00 1.14 0 86.36
27 INT204076 HP Positive_regulation of Gene_expression of Fas 1 0.00 1.81 0 86.04
28 INT304270 Binding of Apoa1 and Scarb1 1 0.00 0.39 0 85.12
29 INT224310 EPAS1 Positive_regulation of CXCL12 1 0.02 0.63 0.05 83.44
30 INT217145 Gene_expression of MIR26B Negative_regulation of Gene_expression of MCL1 1 0.10 1 0 81.68
31 INT351679 Fut1 Negative_regulation of Gene_expression of Flt1 1 0.00 1.01 0 81.48
32 INT329745 AKT1 Negative_regulation of BAD 1 0.03 1.43 0 81.44
33 INT237979 PPARA Negative_regulation of Birc5 1 0.49 1.26 0 80.68
34 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09 80.40
35 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82 80.16
36 INT217776 TP53 Regulation of MITF 1 0.00 1.28 0 79.08
37 INT217774 TP53 Regulation of TSC1 1 0.02 1.28 0 79.08
38 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 78.24
39 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 78.24
40 INT217786 TSC1 Regulation of MITF 1 0.00 1.27 0 78.20
41 INT217143 MIR29A Regulation of Gene_expression of MCL1 1 0.24 1 0 77.92
42 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 77.60
43 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 77.60
44 INT258015 Binding of ANGPT2 and REN 1 0.01 0.59 0.05 77.60
45 INT351682 Fut1 Positive_regulation of PTEN 1 0.01 1.81 0 77.52
46 INT188736 Egfr Regulation of IGLV3-1 1 0.46 0.59 0.03 77.32
47 INT188731 Egfr Regulation of EGFR 1 0.46 0.59 0.03 77.32
48 INT148593 Binding of Gfap and Vim 1 0.06 1.25 0.13 76.16
49 INT307586 Binding of EGFR and CDCP1 1 0.01 0.51 0 75.44
50 INT307585 Binding of EGFR and MET 1 0.11 0.52 0 75.44
51 INT307584 Binding of EGFR and IGF1R 1 0.03 0.52 0 75.44
52 INT194361 VEGFA Regulation of EGFR 1 0.22 1.58 0 75.32
53 INT194362 PDGFA Regulation of EGFR 1 0.23 1.56 0 73.60
54 INT329747 AKT1 Negative_regulation of GSK 1 0.09 1.55 0 73.56
55 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0 71.12
56 INT327341 VEGFA Regulation of Elavl1 1 0.08 1.27 0 69.00
57 INT327335 VEGFA Regulation of Binding of Elavl1 1 0.08 1.27 0 69.00
58 INT258290 Hmgb1 Regulation of Positive_regulation of Tlr2 1 0.46 1.04 0.05 68.64
59 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14 67.36
60 INT204073 Binding of Cdkn2a and Cdk4 1 0.02 0.78 0.05 67.16
61 INT204072 Binding of Cdkn2a and Cdk6 1 0.02 0.78 0.05 67.16
62 INT268512 TP53INP1 Regulation of MIR155 1 0.02 0.97 0 66.80
63 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05 66.08
64 INT204078 Binding of CDKN2A and Cdk4 1 0.15 0.72 0 66.00
65 INT204077 Binding of CDKN2A and Cdk6 1 0.15 0.72 0 66.00
66 INT312939 Binding of Hes3 and Setd1a 1 0.01 0.66 0 62.48
67 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 60.20
68 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0 58.96
69 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0 58.96
70 INT339570 Gene_expression of Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.5 0.23 58.64
71 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05 58.48
72 INT260070 Binding of PHF2 and SPTLC1 1 0.17 1.93 0.1 57.80
73 INT351675 Efna1 Positive_regulation of Epha2 1 0.05 0.68 0 57.60
74 INT286969 IL2 Regulation of Gene_expression of FOXP3 1 0.04 1.05 0.1 56.40
75 INT286955 IL2 Positive_regulation of Binding of STAT3 and FOXP3 1 0.03 0.63 0.06 56.40
76 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22 52.96
77 INT286965 Binding of STAT3 and FOXP3 1 0.27 1.84 0.19 52.96
78 INT279144 RNF139 Regulation of TSN 1 0.24 3.47 0 51.52
79 INT258012 ANGPT2 Positive_regulation of Binding of AGTR1 and ANGPT2 1 0.00 0.29 0.04 50.56
80 INT258020 Binding of AGTR1 and ANGPT2 1 0.03 0.29 0.04 50.56
81 INT188733 Egfr Positive_regulation of Gene_expression of IGLV3-1 1 0.52 0.61 0 50.00
82 INT192913 Binding of ESR1 and HAMP 1 0.02 0.72 0 50.00
83 INT192912 Binding of HAMP and MIER3 1 0.01 0.71 0 50.00
84 INT192915 Binding of ESR1 and MIER3 1 0.00 0.72 0 50.00
85 INT318787 Binding of AKT1 and VEGFA 1 0.37 0.34 0 50.00
86 INT188734 Egfr Positive_regulation of Gene_expression of EGFR 1 0.52 0.61 0 50.00
87 INT192914 Binding of ESR1 and GOPC 2 0.02 0.61 0 50.00
88 INT147144 E2F1 Positive_regulation of Transcription of TYMS 1 0.26 0 0 50.00
89 INT349050 Binding of EPCAM and ZNF845 1 0.02 1.54 0 47.68
90 INT232364 Bgn Negative_regulation of Agxt 1 0.02 0.65 0 46.40
91 INT193120 Trp53 Regulation of Trp53 Regulation of Birc5 1 0.08 0.55 0 46.32
92 INT193119 Trp53 Regulation of Birc5 1 0.19 0.55 0 46.32
93 INT331091 Tert Positive_regulation of Positive_regulation of Cd4 1 0.24 0.76 0 45.16
94 INT237980 CCND3 Regulation of Gene_expression of Birc5 1 0.06 0.96 0 45.12
95 INT352622 Olig2 Negative_regulation of Tpt1 1 0.06 0.54 0.05 44.92
96 INT279143 Binding of TSN and RNF139 1 0.31 0.83 0 44.28
97 INT349051 Binding of EPCAM and SCFV 1 0.03 1.37 0 44.24
98 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05 43.88
99 INT352623 Tpt1 Regulation of Olig2 1 0.02 0.54 0.05 43.88
100 INT217787 Binding of TP53 and MIR208A 1 0.21 0.5 0 41.92
101 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 40.44
102 INT316497 Negative_regulation of Stat3 Negative_regulation of Gene_expression of VEGFA 1 0.13 0.93 0 39.60
103 INT225648 IL4 Positive_regulation of Gene_expression of IL12A 1 0.06 0.89 0.03 38.72
104 INT299552 TGFB1 Positive_regulation of Phosphorylation of Alk 1 0.00 0.12 0 38.60
105 INT237920 PPARA Negative_regulation of STAT3 1 0.16 0.91 0.03 38.28
106 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54 37.52
107 INT279291 PDGFA Positive_regulation of PDGFRB 1 0.16 1.02 0.06 37.52
108 INT279277 PDGFB Positive_regulation of PDGFRB 1 0.14 0.52 0.03 37.52
109 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 36.96
110 INT279276 PDGFA Positive_regulation of NCOR2 1 0.00 1.02 0.06 36.96
111 INT279288 PDGFB Positive_regulation of NCOR2 1 0.00 0.52 0.03 36.96
112 INT279275 PDGFA Positive_regulation of TXK 1 0.05 1.02 0.06 36.16
113 INT279285 PDGFB Positive_regulation of TXK 1 0.05 0.52 0.03 36.16
114 INT301401 Binding of Enpp1 and Enpp2 1 0.23 0.54 0 32.32
115 INT217136 Negative_regulation of MIR221 Negative_regulation of Gene_expression of KIT 1 0.18 0.74 0 31.20
116 INT217138 Negative_regulation of MIR222 Negative_regulation of Gene_expression of KIT 1 0.16 0.74 0 31.20
117 INT258289 Hmgb1 Positive_regulation of Tlr2 4 0.48 3.61 0.19 30.60
118 INT336388 Binding of IL2 and ALPK1 1 0.06 0.73 0.05 29.48
119 INT279280 Binding of PDGFA and PDGFB 1 0.06 0.9 0.06 27.68
120 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 25.12
121 INT292811 Zfp787 Negative_regulation of Phosphorylation of Kdr 1 0.01 0.45 0.06 25.08
122 INT292812 Zfp787 Negative_regulation of Trib3 1 0.00 0.48 0.06 25.08
123 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 24.16
124 INT308702 Binding of AQP4 and CD40LG 1 0.10 0 0 22.92
125 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 22.12
126 INT268510 PDCD4 Regulation of MIR21 1 0.01 1.17 0 19.96
127 INT301414 Binding of Enpp2 and Twist1 1 0.08 1.26 0.13 18.56
128 INT292813 Zfp787 Negative_regulation of Phosphorylation of VEGFA 1 0.01 0.45 0.03 18.32
129 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 16.88
130 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 16.88
131 INT237924 PTPN1 Regulation of Gene_expression of CFLAR 1 0.01 0.7 0.19 16.80
132 INT327829 Aqp1 Regulation of Binding of Csf2 1 0.11 1 0.14 16.40
133 INT328060 LEP Positive_regulation of FAAH 1 0.06 0.7 0.13 14.16
134 INT328058 IL4 Positive_regulation of FAAH 1 0.29 4.29 0.53 13.68
135 INT328064 IL10 Positive_regulation of FAAH 1 0.05 1.48 0.26 12.76
136 INT300696 Sirt1 Regulation of Cyb5r3 1 0.03 0 0 11.36
137 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 9.24
138 INT217773 MIR208A Regulation of Gene_expression of RASGRP1 1 0.06 0.2 0 7.96
139 INT217783 MIR208A Regulation of Gene_expression of MAP3K3 1 0.26 0.2 0 7.96
140 INT301413 Positive_regulation of Binding of Enpp2 and Twist1 1 0.11 0.18 0.03 7.48
141 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32 7.12
142 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11 7.12
143 INT301415 Positive_regulation of Binding of Twist1 and IL19 1 0.11 0.18 0.03 6.84
144 INT301416 Binding of Twist1 and IL19 1 0.08 0.18 0.03 6.84
145 INT217779 POLR2B Regulation of Gene_expression of RASGRP1 1 0.01 0.2 0 6.80
146 INT217785 POLR2B Regulation of Gene_expression of MAP3K3 1 0.06 0.2 0 6.80
147 INT217778 MAP3K3 Regulation of Gene_expression of RASGRP1 1 0.09 0.19 0 6.80
148 INT217777 EIF4E Regulation of Gene_expression of MAP3K3 1 0.05 0.19 0 6.80
149 INT217790 EIF4E Regulation of Gene_expression of RASGRP1 1 0.01 0.19 0 6.80
150 INT217775 CCNL1 Regulation of Gene_expression of RASGRP1 1 0.04 0.25 0 6.80
151 INT217789 CCNL1 Regulation of Gene_expression of MAP3K3 1 0.19 0.25 0 6.80
152 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03 6.52
153 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03 6.52
154 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89 5.00
155 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
156 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3 5.00
157 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
158 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
159 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
160 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
161 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
162 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9 5.00
163 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87 5.00
164 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8 5.00
165 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73 5.00
166 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6 5.00
167 INT327992 TRPV1 Positive_regulation of Gene_expression of ROS1 1 0.28 0.35 0.6 5.00
168 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58 5.00
169 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58 5.00
170 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58 5.00
171 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57 5.00
172 INT115146 MAPK1 Positive_regulation of EGR1 3 0.13 2.43 0.57 5.00
173 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
174 INT169648 IGHG3 Regulation of AQP4 3 0.02 4.63 0.55 5.00
175 INT156517 Binding of CNR1 and FAAH 3 0.38 1.53 0.53 5.00
176 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52 5.00
177 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49 5.00
178 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48 5.00
179 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 0.02 0.21 0.48 5.00
180 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48 5.00
181 INT240441 Ltb4r1 Positive_regulation of PPARA 1 0.03 1.01 0.47 5.00
182 INT327995 Positive_regulation of TRPV1 Positive_regulation of Tnfrsf1a 1 0.16 0.63 0.46 5.00
183 INT240442 Binding of PPARA and Ltb4r1 1 0.02 0.94 0.46 5.00
184 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45 5.00
185 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45 5.00
186 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 5.00
187 INT327991 Positive_regulation of TRPV1 Positive_regulation of ROS1 1 0.26 0.2 0.4 5.00
188 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36 5.00
189 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
190 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34 5.00
191 INT240434 PPARA Negative_regulation of Gene_expression of CPOX 1 0.03 0.64 0.33 5.00
192 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33 5.00
193 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
194 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
195 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
196 INT308701 Binding of AQP4 and DDX41 1 0.15 3.53 0.32 5.00
197 INT239079 D0H4S114 Positive_regulation of Gene_expression of Cpa1 1 0.11 0.3 0.32 5.00
198 INT316488 Il22 Positive_regulation of Il10 1 0.29 0.63 0.32 5.00
199 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31 5.00
200 INT316483 Il22ra1 Positive_regulation of Il10 1 0.27 0.62 0.31 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glioblastoma. They are ordered first by their pain relevance and then by number of times they were reported in Glioblastoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT113705 Gene_expression of Egfr 228 0.78 149.05 7.59 100.00
2 INT138696 Positive_regulation of Ccl2 57 0.67 59.57 19.58 100.00
3 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15 100.00
4 INT123131 Negative_regulation of Negative_regulation of AKT1 6 0.42 3.23 0.58 100.00
5 INT177886 Positive_regulation of Gene_expression of Cdkn2a 3 0.67 3.42 0.62 100.00
6 INT335530 Positive_regulation of Gene_expression of SPHK1 1 0.69 21.31 0 100.00
7 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12 100.00
8 INT204062 Negative_regulation of Gene_expression of Cdk4 1 0.12 0.47 0 100.00
9 INT204064 Negative_regulation of Gene_expression of Cdk2 1 0.11 0.47 0 100.00
10 INT204061 Negative_regulation of Gene_expression of Cdk6 1 0.12 0.47 0 100.00
11 INT204068 Negative_regulation of Gene_expression of Ccne1 1 0.03 0.47 0 100.00
12 INT258269 Localization of tk 5 0.25 5.3 0.17 100.00
13 INT229563 Localization of Flt3l 2 0.62 3.13 0.05 100.00
14 INT215071 Positive_regulation of Localization of Hmgb1 34 0.63 22.03 4.15 100.00
15 INT191343 Gene_expression of IDO1 23 0.55 11.3 4.81 100.00
16 INT203047 Gene_expression of CD274 16 0.52 12.32 2.21 100.00
17 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
18 INT86246 Binding of Bcl2l1 8 0.37 6.67 0.57 100.00
19 INT352599 Binding of Bcl2l12 1 0.20 0.88 0.04 100.00
20 INT180185 Gene_expression of MGMT 22 0.65 15.02 1.57 99.98
21 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.98
22 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61 99.96
23 INT312933 Localization of Hes3 1 0.63 7.94 0.53 99.96
24 INT163545 Gene_expression of PDGFRB 39 0.78 25.5 2.2 99.96
25 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 99.92
26 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 99.92
27 INT336398 Negative_regulation of Gene_expression of CD1D 1 0.15 1 0 99.90
28 INT270574 Gene_expression of IL13RA2 9 0.68 5.46 0.42 99.88
29 INT142435 Gene_expression of NES 86 0.78 47.53 4.92 99.86
30 INT113602 Positive_regulation of Gene_expression of Ccl2 48 0.70 48.71 17.85 99.86
31 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 99.86
32 INT143759 Gene_expression of SOX2 46 0.55 11.12 1.24 99.86
33 INT188724 Gene_expression of IGLV3-1 29 0.75 20.88 0.51 99.84
34 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 99.84
35 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 99.84
36 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.84
37 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 99.84
38 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 99.84
39 INT280594 Gene_expression of SPHK1 2 0.78 71.47 0.19 99.84
40 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39 99.84
41 INT303585 Gene_expression of Coro1c 1 0.63 18.63 0.15 99.84
42 INT75505 Regulation of Gene_expression of CDKN1A 24 0.60 12.24 3.07 99.84
43 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 99.84
44 INT102234 Gene_expression of ESR2 17 0.65 9.29 2.3 99.84
45 INT338714 Binding of PROM1 1 0.21 2.04 0 99.84
46 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 99.84
47 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 99.84
48 INT235344 Regulation of Nfix 1 0.39 0.71 0 99.84
49 INT217217 Negative_regulation of MIR128-2 1 0.19 0.89 0 99.84
50 INT217196 Negative_regulation of MIR181A2 1 0.07 0.89 0 99.84
51 INT217176 Negative_regulation of MIR181B2 1 0.06 0.89 0 99.84
52 INT217192 Negative_regulation of MIR181C 1 0.17 0.89 0 99.84
53 INT303584 Positive_regulation of Gene_expression of Coro1c 1 0.38 4.19 0 99.84
54 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 99.84
55 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17 99.84
56 INT352601 Gene_expression of Bcl2l12 1 0.33 0.81 0.04 99.84
57 INT272338 Negative_regulation of Adarb1 4 0.46 8.88 0.43 99.82
58 INT94628 Gene_expression of CD1D 12 0.75 5.58 2.13 99.82
59 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 99.80
60 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.80
61 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.80
62 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 99.80
63 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 99.78
64 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 99.78
65 INT193612 Transcription of SART1 2 0.58 1.56 0.03 99.78
66 INT336402 Transcription of AIM2 1 0.23 0.85 0.03 99.78
67 INT336400 Transcription of MAGEA1 1 0.31 0.84 0.03 99.78
68 INT336403 Transcription of SOX11 1 0.24 0.84 0.03 99.78
69 INT190447 Transcription of SOX2 5 0.36 0.84 0.11 99.78
70 INT319048 Transcription of WT1 2 0.56 1.87 0.16 99.78
71 INT336399 Transcription of EPHA2 1 0.24 2.21 0.03 99.78
72 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 99.76
73 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 99.76
74 INT258281 Binding of tk 6 0.12 6.21 0.26 99.74
75 INT217804 Negative_regulation of MITF 19 0.01 19.95 0.57 99.74
76 INT117660 Gene_expression of Prom1 50 0.73 39.62 3.07 99.72
77 INT101866 Positive_regulation of Gene_expression of AKT1 49 0.52 17.47 2.14 99.72
78 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 99.72
79 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55 99.72
80 INT174241 Gene_expression of ADCY5 2 0.65 1 0.14 99.72
81 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.68
82 INT17331 Positive_regulation of JUN 132 0.69 60.4 27.03 99.68
83 INT123343 Negative_regulation of LAMC1 1 0.27 2.62 1.26 99.60
84 INT192916 Gene_expression of MIER3 1 0.04 2.47 0 99.60
85 INT164518 Gene_expression of PPIA 7 0.75 3.92 0.5 99.60
86 INT166737 Positive_regulation of Gene_expression of PPIA 1 0.68 2.5 0.15 99.60
87 INT147152 Negative_regulation of E2F1 6 0.56 0.89 0.38 99.60
88 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.56
89 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 99.56
90 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 99.56
91 INT66040 Positive_regulation of Bdnf 114 0.69 67.67 51.81 99.56
92 INT77795 Localization of Gdnf 26 0.81 6.29 8.55 99.56
93 INT260030 Localization of PROM1 5 0.70 4.36 0 99.56
94 INT69878 Positive_regulation of Gene_expression of Gtf3a 48 0.29 36.78 13.57 99.56
95 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.56
96 INT71689 Localization of Ntf3 23 0.73 11.1 7.91 99.56
97 INT98652 Positive_regulation of Localization of Ntf3 2 0.40 1.42 2.15 99.56
98 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 99.56
99 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.54
100 INT39456 Positive_regulation of Soat2 1 0.49 0.2 0.96 99.48
101 INT285145 Positive_regulation of MGMT 3 0.48 4.09 0.26 99.44
102 INT154392 Regulation of HPGD 2 0.44 1.37 0.95 99.44
103 INT58989 Gene_expression of Ccne1 2 0.75 0.79 0.58 99.40
104 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27 99.40
105 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.40
106 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38 99.36
107 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 99.36
108 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.36
109 INT216144 Positive_regulation of MIR21 4 0.19 2.59 0.19 99.34
110 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02 99.34
111 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42 99.34
112 INT74237 Positive_regulation of Ppt1 3 0.49 2.92 2.32 99.34
113 INT235343 Regulation of Nfia 1 0.10 0.46 0 99.32
114 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39 99.32
115 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 99.30
116 INT173967 Gene_expression of Mri1 26 0.43 16.67 6.45 99.28
117 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 99.28
118 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19 99.28
119 INT45272 Regulation of Nps 15 0.39 8.08 2.69 99.28
120 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 99.26
121 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 99.24
122 INT185835 Negative_regulation of Gene_expression of MMP7 4 0.35 2.35 0.46 99.24
123 INT261715 Positive_regulation of Wisp1 1 0.02 1.89 0.03 99.20
124 INT210246 Gene_expression of Pmel 3 0.16 2.27 0 99.16
125 INT62421 Gene_expression of Trpc2 8 0.68 5.48 0.67 99.16
126 INT131978 Gene_expression of Trpc1 15 0.71 4.67 3.19 99.16
127 INT18185 Gene_expression of Tyr 32 0.76 12.52 8.17 99.16
128 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05 99.16
129 INT15198 Regulation of Gene_expression of Gtf3a 13 0.10 8.63 3.34 99.12
130 INT11318 Gene_expression of Gtf3a 274 0.52 183.82 60.89 99.12
131 INT169747 Localization of AQP4 17 0.75 16.64 2.79 99.10
132 INT195016 Gene_expression of Aifm1 8 0.45 5.92 0.78 99.08
133 INT74389 Gene_expression of Gdnf 131 0.78 58.52 57.06 99.08
134 INT79981 Positive_regulation of Gene_expression of Gdnf 27 0.70 12.49 10.77 99.08
135 INT235345 Regulation of Nfib 1 0.10 0.46 0 99.08
136 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 99.08
137 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53 99.08
138 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 99.08
139 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08 99.08
140 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.04
141 INT10304 Binding of OPRK1 89 0.48 9.28 49.42 99.04
142 INT331076 Gene_expression of H27 1 0.01 6.45 0.29 99.02
143 INT10237 Binding of EDN1 40 0.48 16 8.48 99.00
144 INT261719 Negative_regulation of Negative_regulation of Dbm2 1 0.45 1.25 0 98.98
145 INT93684 Gene_expression of STAT3 66 0.78 34.42 5.94 98.96
146 INT262963 Negative_regulation of PAX6 4 0.59 4.92 0.04 98.92
147 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 98.90
148 INT89401 Negative_regulation of Phosphorylation of AKT1 68 0.58 35.61 2.8 98.88
149 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 98.88
150 INT120563 Positive_regulation of Gene_expression of Egfr 56 0.70 46.19 1.82 98.88
151 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65 98.88
152 INT28865 Positive_regulation of Gene_expression of Cea 21 0.57 15.03 2.52 98.88
153 INT191073 Negative_regulation of Gene_expression of Mki67 8 0.53 4.99 0.11 98.88
154 INT140296 Negative_regulation of XIAP 9 0.45 13.61 1.37 98.86
155 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 98.84
156 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.84
157 INT102233 Gene_expression of MMP7 40 0.76 15.78 2.93 98.84
158 INT103828 Negative_regulation of Gene_expression of TRPV1 23 0.59 13.63 13.81 98.84
159 INT95674 Positive_regulation of HPGD 7 0.67 3.7 2.59 98.82
160 INT156132 Gene_expression of Aqp9 26 0.49 14.33 3.48 98.82
161 INT159293 Negative_regulation of PMS1 2 0.03 1.94 0 98.82
162 INT192340 Regulation of PDGFRB 4 0.45 3.83 0.03 98.80
163 INT328279 Positive_regulation of Regulation of PDGFRB 1 0.37 0.74 0 98.80
164 INT321564 Positive_regulation of Protein_catabolism of Ctsb 1 0.16 0.92 0.12 98.80
165 INT321559 Regulation of Protein_catabolism of Ctsb 1 0.10 0.89 0.11 98.80
166 INT321566 Protein_catabolism of Ctsb 2 0.23 1.07 0.06 98.80
167 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 98.78
168 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48 98.76
169 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72 98.76
170 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 98.76
171 INT119269 Binding of CDKN1A 14 0.47 8.82 0.31 98.76
172 INT235349 Regulation of Nfic 1 0.21 0.46 0 98.72
173 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 98.68
174 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 98.68
175 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 98.64
176 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 98.64
177 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 98.64
178 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 98.62
179 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 98.60
180 INT335535 Positive_regulation of SPHK1 1 0.69 12.71 0 98.60
181 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61 98.60
182 INT81453 Positive_regulation of Gene_expression of JUN 18 0.50 9.39 3.23 98.60
183 INT111039 Gene_expression of Kras 20 0.60 15.42 2.39 98.56
184 INT23122 Gene_expression of Ptger3 31 0.72 11.94 11.37 98.56
185 INT92316 Gene_expression of Plaur 30 0.61 22.06 2.21 98.52
186 INT193847 Gene_expression of Met 22 0.65 6.6 0.24 98.52
187 INT92003 Positive_regulation of Transcription of Gdnf 10 0.66 5.54 7.84 98.52
188 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 98.48
189 INT166739 Positive_regulation of PPIA 1 0.45 1.39 0.06 98.48
190 INT204060 Gene_expression of Cdk6 3 0.26 0.83 0 98.44
191 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 98.44
192 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 98.36
193 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 98.36
194 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 98.36
195 INT94772 Gene_expression of Cdkn2a 14 0.75 8.25 2.04 98.36
196 INT225812 Localization of EIF3A 1 0.08 1.24 0 98.36
197 INT95120 Positive_regulation of CASP9 76 0.67 67.55 5.33 98.36
198 INT164735 Gene_expression of MIR29A 4 0.75 2.98 0.24 98.28
199 INT217120 Gene_expression of Mir181a-2 3 0.58 2.52 0 98.28
200 INT110343 Negative_regulation of PIK3CD 22 0.40 5.84 4.2 98.20
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