D:Gliosarcoma

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Disease Term
Synonyms Glioblastoma With Sarcomatous Component, Glioma Sarcomatous, Gliomas Sarcomatous, GLIOSARCOMAS, Sarcomatous Glioma, Sarcomatous Gliomas
Documents 34
Hot Single Events 6
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gliosarcoma. They are ordered first by their relevance to Gliosarcoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 0.06 1.2 0.25 80.64
2 INT225649 IL4 Positive_regulation of Localization of DCPS 1 0.02 1.03 0.19 65.60
3 INT225648 IL4 Positive_regulation of Gene_expression of IL12A 1 0.06 0.89 0.03 29.08
4 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
5 INT339532 FGF2 Positive_regulation of YWHAZ 1 0.00 1.26 0.54 5.00
6 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
7 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
8 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
9 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
10 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
11 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
12 INT339570 Gene_expression of Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.5 0.23 5.00
13 INT323436 VEGFA Regulation of Kdr 1 0.03 0.77 0.23 5.00
14 INT339535 FGF2 Positive_regulation of Gene_expression of CYP4A11 1 0.00 0.55 0.22 5.00
15 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21 5.00
16 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2 5.00
17 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16 5.00
18 INT323430 Binding of Vhl and Osr1 1 0.02 0.78 0.13 5.00
19 INT323439 Osr1 Regulation of Binding of Osr1 and Gtf3a 1 0.00 0.79 0.13 5.00
20 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
21 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13 5.00
22 INT330369 Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
23 INT323435 Binding of Osr1 and Gtf3a 1 0.00 0.78 0.13 5.00
24 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13 5.00
25 INT323438 Binding of Hif1a and Vhl Positive_regulation of Positive_regulation of Hif1a 1 0.05 0.74 0.12 5.00
26 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12 5.00
27 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1 5.00
28 INT339533 VEGFA Positive_regulation of Gene_expression of CYP2C8 1 0.09 0.57 0.09 5.00
29 INT339534 VEGFA Positive_regulation of CYP2C18 1 0.04 0.57 0.08 5.00
30 INT225650 DCPS Positive_regulation of PDHA1 1 0.00 0.41 0.07 5.00
31 INT339569 VEGFA Positive_regulation of Litaf 1 0.18 0.6 0.04 5.00
32 INT330372 Ifx Positive_regulation of IFNA1 1 0.54 0.67 0.04 5.00
33 INT174204 Binding of SYNE1 and IL19 1 0.06 0.47 0.03 5.00
34 INT307704 Binding of Gsr and Rb(8.17)6Sic 1 0.01 1.49 0.03 5.00
35 INT174203 Binding of NTSR1 and FMN1 1 0.01 0.06 0 5.00
36 INT232364 Bgn Negative_regulation of Agxt 1 0.02 0.65 0 5.00
37 INT174205 PPIG Positive_regulation of CPA1 1 0.01 0.33 0 5.00
38 INT330384 IER3 Regulation of USH2A 1 0.00 0.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gliosarcoma. They are ordered first by their pain relevance and then by number of times they were reported in Gliosarcoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68216 Binding of NF1 40 0.48 51.24 4.59 99.98
2 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 96.40
3 INT179101 Gene_expression of CYP4F3 14 0.65 6.89 1.98 92.56
4 INT43415 Gene_expression of CYP4A11 11 0.56 7.65 5.94 91.40
5 INT162444 Positive_regulation of CYP4A11 4 0.43 4.11 0.61 87.80
6 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 80.80
7 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 78.68
8 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16 78.68
9 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 75.00
10 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 75.00
11 INT27740 Positive_regulation of COX8A 16 0.67 9.66 3.23 75.00
12 INT80329 Positive_regulation of THBD 12 0.47 20.96 2.45 75.00
13 INT101859 Gene_expression of MCF2 34 0.49 19.45 1.51 74.96
14 INT64473 Regulation of Gene_expression of IL4 17 0.58 6.61 3.96 70.36
15 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 64.24
16 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 64.24
17 INT91667 Localization of IL12A 39 0.74 25.51 7.36 63.08
18 INT159632 Localization of DCPS 24 0.21 18.24 6.8 62.84
19 INT172370 Binding of MCPH1 6 0.34 4.75 0.13 62.64
20 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 57.36
21 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55 55.92
22 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 50.00
23 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 50.00
24 INT7093 Negative_regulation of CYP2B6 146 0.58 37.3 48.39 48.92
25 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82 48.72
26 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 40.76
27 INT225659 Gene_expression of TFG 2 0.65 1.68 0.32 38.64
28 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 31.48
29 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55 30.96
30 INT174190 Regulation of Gene_expression of TKT 4 0.43 2.99 0.03 30.96
31 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97 27.92
32 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 27.68
33 INT36177 Binding of Alms1 70 0.31 35.47 13.81 26.96
34 INT194322 Positive_regulation of CST7 1 0.32 0.39 0.17 9.64
35 INT225654 Gene_expression of PDHA1 8 0.44 3.18 0.25 9.04
36 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
37 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
38 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
39 INT4740 Gene_expression of Th 298 0.78 61.27 154.03 5.00
40 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
41 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
42 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
43 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 5.00
44 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
45 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
46 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
47 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
48 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 5.00
49 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
50 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 5.00
51 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
52 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 5.00
53 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 5.00
54 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
55 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
56 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
57 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
58 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
59 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
60 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
61 INT69876 Negative_regulation of Nfkb1 147 0.58 89.81 55.5 5.00
62 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
63 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 5.00
64 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 5.00
65 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
66 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 5.00
67 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 5.00
68 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
69 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 5.00
70 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 5.00
71 INT133028 Gene_expression of TLR2 209 0.73 131.92 36.17 5.00
72 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
73 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
74 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 5.00
75 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
76 INT5489 Localization of CA2 172 0.80 39.46 33.56 5.00
77 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
78 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
79 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 5.00
80 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
81 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
82 INT110020 Gene_expression of Mapk14 142 0.77 72.33 30.08 5.00
83 INT21900 Gene_expression of Mthfd1 150 0.75 69.47 27.03 5.00
84 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
85 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
86 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 5.00
87 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 5.00
88 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 5.00
89 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
90 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38 5.00
91 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68 5.00
92 INT116856 Gene_expression of TNFSF10 110 0.75 115.76 21.48 5.00
93 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 5.00
94 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
95 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
96 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
97 INT20129 Regulation of Il1 53 0.53 44.14 19.89 5.00
98 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
99 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
100 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
101 INT73252 Positive_regulation of Mthfd1 124 0.59 59.48 18.35 5.00
102 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 5.00
103 INT33542 Gene_expression of Il1rn 41 0.76 32.47 18.08 5.00
104 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
105 INT168263 Gene_expression of IL23A 57 0.58 47.1 17.67 5.00
106 INT10555 Gene_expression of FLII 37 0.75 7.81 17.6 5.00
107 INT84924 Positive_regulation of Gene_expression of NGF 29 0.68 17.91 16.46 5.00
108 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
109 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
110 INT97871 Gene_expression of Ntf3 47 0.78 25.9 15.94 5.00
111 INT9220 Gene_expression of Ighg1 125 0.77 85.74 15.92 5.00
112 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34 5.00
113 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21 5.00
114 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 5.00
115 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
116 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 5.00
117 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
118 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48 5.00
119 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07 5.00
120 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
121 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93 5.00
122 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66 5.00
123 INT85048 Regulation of NGF 19 0.62 11.61 10.5 5.00
124 INT150540 Binding of TLR2 50 0.45 35.86 10.43 5.00
125 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09 5.00
126 INT21952 Gene_expression of GDNF 42 0.78 20.32 9.62 5.00
127 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53 5.00
128 INT21214 Negative_regulation of Gene_expression of PENK 21 0.58 9.14 9.53 5.00
129 INT182137 Gene_expression of TLR9 137 0.78 48.48 9.05 5.00
130 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96 5.00
131 INT61264 Regulation of Jun 36 0.61 18.42 8.71 5.00
132 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 5.00
133 INT108202 Positive_regulation of PIK3CG 47 0.67 25.83 8.25 5.00
134 INT92680 Gene_expression of Fgf2 59 0.77 28.11 8.12 5.00
135 INT97870 Positive_regulation of Gene_expression of Ntf3 19 0.70 9.56 7.8 5.00
136 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 5.00
137 INT1664 Gene_expression of Kitl 30 0.65 13.63 7.47 5.00
138 INT51741 Regulation of Gene_expression of Il4 23 0.36 12.7 7.39 5.00
139 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27 5.00
140 INT63373 Negative_regulation of Gene_expression of NGF 14 0.57 8.9 7.1 5.00
141 INT2039 Regulation of CYP2B6 30 0.60 7.75 6.43 5.00
142 INT137206 Positive_regulation of TLR2 47 0.65 33.36 6.4 5.00
143 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07 5.00
144 INT68661 Positive_regulation of NTSR1 11 0.69 9.6 5.91 5.00
145 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88 5.00
146 INT147263 Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 51 0.53 15.32 5.86 5.00
147 INT56160 Binding of Ifx 14 0.36 11.39 5.74 5.00
148 INT68899 Binding of CYP1A2 19 0.48 2.33 5.73 5.00
149 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51 5.00
150 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44 5.00
151 INT18772 Positive_regulation of Gene_expression of CYP2B6 14 0.49 2.93 5.4 5.00
152 INT77146 Binding of IL4 23 0.36 13.69 5.39 5.00
153 INT126751 Regulation of Gene_expression of IL10 16 0.44 10.84 5.22 5.00
154 INT39256 Localization of PTGS1 17 0.74 6.62 5.1 5.00
155 INT175312 Positive_regulation of Gene_expression of IL23A 17 0.45 14.8 5.05 5.00
156 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
157 INT130290 Positive_regulation of Localization of IL10 16 0.47 9.38 4.75 5.00
158 INT124136 Positive_regulation of YWHAZ 7 0.67 1.85 4.51 5.00
159 INT188588 Localization of Mthfd1 20 0.49 9.19 4.37 5.00
160 INT94863 Gene_expression of Litaf 27 0.65 10.21 4.35 5.00
161 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 5.00
162 INT50581 Regulation of PPIG 26 0.55 8.96 4.32 5.00
163 INT1209 Binding of Kitl 14 0.37 6.72 4.3 5.00
164 INT3327 Protein_catabolism of PRSS1 22 1.00 6.96 4.29 5.00
165 INT73503 Positive_regulation of Gene_expression of IL13 16 0.37 14.6 4.23 5.00
166 INT26584 Gene_expression of Nes 76 0.75 24.03 4.17 5.00
167 INT204529 Positive_regulation of TLR9 18 0.62 15.62 3.99 5.00
168 INT92653 Gene_expression of IL12B 21 0.75 17.28 3.89 5.00
169 INT144231 Gene_expression of Il12b 18 0.75 12.93 3.65 5.00
170 INT5609 Regulation of Ifx 6 0.60 5.73 3.5 5.00
171 INT66585 Gene_expression of IER3 13 0.63 7.39 3.48 5.00
172 INT167478 Positive_regulation of Gene_expression of DCPS 23 0.27 14.75 3.37 5.00
173 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36 5.00
174 INT174232 Gene_expression of PNP 36 0.30 8.74 3.17 5.00
175 INT47011 Positive_regulation of Gusb 14 0.44 8.93 2.87 5.00
176 INT188590 Positive_regulation of Gene_expression of Mthfd1 23 0.49 16.56 2.84 5.00
177 INT8095 Gene_expression of ERBB3 47 0.77 24.85 2.82 5.00
178 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77 5.00
179 INT204524 Binding of TLR9 17 0.43 11.69 2.76 5.00
180 INT75685 Regulation of CD86 12 0.58 3.55 2.66 5.00
181 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66 5.00
182 INT133029 Regulation of TLR2 18 0.56 11.31 2.62 5.00
183 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61 5.00
184 INT36338 Gene_expression of NRP2 29 0.67 6.47 2.4 5.00
185 INT68658 Gene_expression of NTSR1 17 0.77 7.88 2.32 5.00
186 INT134626 Positive_regulation of Gene_expression of Kdr 20 0.63 14.63 2.29 5.00
187 INT29402 Gene_expression of Src 16 0.74 4.57 2.29 5.00
188 INT150192 Positive_regulation of CPA1 3 0.23 1.29 2.2 5.00
189 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19 5.00
190 INT181015 Gene_expression of C3ar1 12 0.58 8.9 2.18 5.00
191 INT12131 Gene_expression of POR 17 0.77 9.42 2.17 5.00
192 INT65424 Positive_regulation of Gene_expression of CYP1A2 6 0.70 2.01 2.01 5.00
193 INT100046 Gene_expression of BTG2 16 0.20 10.81 1.95 5.00
194 INT89253 Regulation of Mthfd1 14 0.23 8.1 1.94 5.00
195 INT65880 Gene_expression of CYP2C8 25 0.77 9.49 1.92 5.00
196 INT184006 Gene_expression of Ighg2b 21 0.71 7.97 1.86 5.00
197 INT197166 Gene_expression of Cyp4a10 27 0.75 15.63 1.81 5.00
198 INT23148 Gene_expression of RUNX1 10 0.10 6.58 1.71 5.00
199 INT104220 Positive_regulation of Gene_expression of PPIG 14 0.49 7.38 1.7 5.00
200 INT67704 Negative_regulation of Negative_regulation of CYP2B6 3 0.41 1.69 1.66 5.00
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