D:Glomerulonephritis

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Disease Term
Synonyms BRIGHT DISEASE, Bright S Disease, Disease Bright, Glomerular Nephritis, Glomerulonephritides, Glomerulonephritis Disorder, Gn Glomerulonephritis, Heymann Nephritis, Nephritis Glomerular, Nephritis Heymann, Unspecified Glomerulonephritis
Documents 14
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glomerulonephritis. They are ordered first by their relevance to Glomerulonephritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 77.20
2 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 74.16
3 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 74.16
4 INT279510 Binding of C1qa and fc 1 0.01 0.36 0 59.00
5 INT279504 Binding of C1ra and Positive_regulation of C1s 1 0.04 0.33 0 54.56
6 INT279508 Binding of Arhgap4 and Positive_regulation of C1s 1 0.01 0.33 0 54.56
7 INT279505 Binding of C4b and Abpz 1 0.01 0.21 0 50.80
8 INT279509 Binding of C2 and Abpz 1 0.01 0.21 0 50.52
9 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 48.52
10 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 48.52
11 INT279501 C3ar1 Positive_regulation of C3 1 0.01 0 0 40.40
12 INT229983 Binding of CFH and Crp 2 0.14 1.48 0 21.36
13 INT279502 Binding of C2 and Hc 1 0.01 0.2 0.07 14.28
14 INT279503 Binding of C1s and C1ra 1 0.03 0.58 0.22 5.00
15 INT279507 Serping1 Negative_regulation of Gene_expression of C3 1 0.03 1.12 0.19 5.00
16 INT279500 Serping1 Negative_regulation of Transcription of C3 1 0.03 1.12 0.19 5.00
17 INT279511 Binding of Serping1 and C1ra 1 0.01 0.3 0.11 5.00
18 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04 5.00
19 INT279515 Daf2 Negative_regulation of INCENP 1 0.00 0 0 5.00
20 INT177566 Binding of Gtayu6 and Syf2 1 0.00 0.13 0 5.00
21 INT279514 Cr1l Negative_regulation of INCENP 1 0.00 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glomerulonephritis. They are ordered first by their pain relevance and then by number of times they were reported in Glomerulonephritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT86183 Binding of Igha 2 0.47 1.5 0.27 97.64
2 INT279457 Negative_regulation of Daf2 1 0.14 3.17 0.09 97.16
3 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 97.10
4 INT177556 Gene_expression of Tpr 9 0.34 2.71 0.48 96.96
5 INT23667 Gene_expression of Hgfac 10 0.03 6.74 2.19 96.96
6 INT2733 Negative_regulation of Tbxas1 33 0.57 12.12 6.97 96.88
7 INT182854 Negative_regulation of AAVS1 4 0.06 1.98 0.15 96.86
8 INT177552 Negative_regulation of Hgfac 1 0.02 0.93 0 94.32
9 INT182852 Regulation of AAVS1 4 0.12 4.6 1.03 92.60
10 INT154180 Negative_regulation of SYK 3 0.43 4.67 0.5 91.24
11 INT27995 Regulation of Tbxas1 8 0.19 1.54 1.4 89.04
12 INT178198 Gene_expression of C3 62 0.78 39.5 7.69 87.92
13 INT135963 Negative_regulation of Hc 19 0.42 12.36 3.63 85.12
14 INT279456 Binding of Ly76 1 0.02 1.26 0.18 84.64
15 INT171010 Binding of IL5 6 0.36 4.11 2.12 84.60
16 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 80.76
17 INT184365 Negative_regulation of C3 19 0.43 13.86 2.89 78.08
18 INT51014 Transcription of IL2 42 0.71 21.56 12.7 77.20
19 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 75.20
20 INT138844 Positive_regulation of CC2D1A 25 0.41 41.36 1.92 74.92
21 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 74.40
22 INT73504 Binding of CD28 35 0.45 15.99 10.04 74.16
23 INT144652 Negative_regulation of Binding of CD28 6 0.55 3.09 2.28 74.16
24 INT279459 Negative_regulation of Cd59a 3 0.58 5.76 0.5 73.76
25 INT177549 Binding of Eif2s1 1 0.04 0.73 0 67.68
26 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 67.68
27 INT45004 Gene_expression of Cfb 28 0.37 15.06 1.99 67.40
28 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 65.16
29 INT190418 Positive_regulation of AAVS1 15 0.49 4.71 0.98 63.28
30 INT116228 Binding of C1qa 26 0.47 15.72 3 59.00
31 INT279443 Binding of Cd59a 1 0.14 0.92 0.17 57.44
32 INT184390 Binding of Arhgap4 13 0.36 3.29 3.35 54.56
33 INT263705 Binding of C1ra 2 0.36 0.62 0.26 54.56
34 INT149027 Positive_regulation of C1s 8 0.36 4.27 0.51 51.68
35 INT160252 Gene_expression of C1s 5 0.21 1.49 0.03 51.28
36 INT60764 Positive_regulation of PPIG 39 0.67 17.08 13.48 47.60
37 INT220896 Protein_catabolism of C4b 2 0.66 0.26 0.04 43.92
38 INT279450 Protein_catabolism of C2 1 0.20 0 0 43.92
39 INT279462 Regulation of Protein_catabolism of C2 1 0.10 0 0 43.92
40 INT279461 Regulation of Protein_catabolism of C4b 1 0.06 0 0 43.92
41 INT218465 Regulation of Binding of Cfb 2 0.05 0 0 43.04
42 INT279446 Regulation of Binding of C3 1 0.18 0 0 43.04
43 INT155160 Binding of C3 20 0.47 7.77 2.61 42.80
44 INT184378 Binding of Cfb 54 0.20 12.49 2.36 42.80
45 INT177553 Gene_expression of Syf2 1 0.01 0.06 0 41.80
46 INT179532 Protein_catabolism of C3 5 0.26 1.61 0.34 40.40
47 INT16772 Gene_expression of MPO 81 0.78 90.98 11.9 39.68
48 INT198606 Localization of CFH 8 0.65 4.37 0.04 38.00
49 INT250743 Localization of CC2D1A 12 0.51 20.97 0.51 37.36
50 INT127435 Gene_expression of Per1 89 0.77 13.94 22.31 37.20
51 INT67279 Localization of PRTN3 11 0.50 14.18 4.3 36.24
52 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 34.88
53 INT254308 Negative_regulation of TNFSF13B 10 0.42 5.12 1.25 31.92
54 INT179542 Positive_regulation of C3 27 0.52 19.39 3.83 28.64
55 INT181015 Gene_expression of C3ar1 12 0.58 8.9 2.18 28.20
56 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 25.44
57 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 25.44
58 INT46 Localization of Ren 233 0.81 46.15 62.44 25.00
59 INT48 Positive_regulation of Localization of Ren 69 0.70 12.47 18.03 25.00
60 INT30531 Gene_expression of C2 15 0.66 5.5 1.99 17.00
61 INT74166 Positive_regulation of C2 10 0.55 2.83 1.05 17.00
62 INT279460 Positive_regulation of Gene_expression of C2 1 0.10 0.14 0.04 17.00
63 INT153776 Positive_regulation of IL17A 42 0.64 34.58 14.82 16.64
64 INT155010 Positive_regulation of Gene_expression of IL17A 23 0.64 20.17 7.15 16.64
65 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 16.40
66 INT150222 Positive_regulation of Gene_expression of TNFSF13B 12 0.11 7.49 2.43 13.60
67 INT184367 Protein_catabolism of Hc 4 0.26 2.66 0.6 13.48
68 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 11.12
69 INT44602 Gene_expression of TNFSF13B 37 0.75 30.98 9.96 11.12
70 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 10.92
71 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 10.92
72 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 10.56
73 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
74 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
75 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
76 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
77 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
78 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
79 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
80 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
81 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
82 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
83 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 5.00
84 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 5.00
85 INT2774 Binding of Crp 241 0.48 195.89 44.39 5.00
86 INT23222 Binding of Phax 52 0.31 7.61 30.4 5.00
87 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
88 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 5.00
89 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 5.00
90 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
91 INT49985 Transcription of Il6 62 0.72 40.13 20.29 5.00
92 INT1278 Negative_regulation of Ldha 93 0.59 37.66 19.36 5.00
93 INT85639 Positive_regulation of Tg(CAG-EGFP)D4Nagy 95 0.43 24.83 15.69 5.00
94 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
95 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 5.00
96 INT50580 Binding of PPIG 39 0.36 11.17 12.34 5.00
97 INT70877 Gene_expression of PPIG 72 0.75 22.39 10.93 5.00
98 INT56223 Positive_regulation of MPO 35 0.70 43 8.2 5.00
99 INT167052 Gene_expression of Cr2 43 0.56 25.7 7.76 5.00
100 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27 5.00
101 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 5.00
102 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92 5.00
103 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 5.00
104 INT211133 Negative_regulation of MTX1 8 0.19 3.86 4.87 5.00
105 INT69904 Binding of Hc 11 0.35 7.79 3.69 5.00
106 INT28923 Negative_regulation of Ldha 8 0.58 4.94 3.11 5.00
107 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07 5.00
108 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97 5.00
109 INT177551 Negative_regulation of Tg(CAG-EGFP)D4Nagy 31 0.37 11.16 2.65 5.00
110 INT82966 Transcription of Crp 14 0.70 9.91 2.61 5.00
111 INT21516 Negative_regulation of Positive_regulation of Ldha 13 0.43 4.73 2.53 5.00
112 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 5.00
113 INT4585 Gene_expression of Serping1 19 0.46 12.4 2.35 5.00
114 INT133567 Regulation of IL18 11 0.50 9.54 2.31 5.00
115 INT23748 Localization of Ltf 15 0.79 5.43 2.07 5.00
116 INT14184 Positive_regulation of CPB1 23 0.55 14.38 1.73 5.00
117 INT565 Negative_regulation of Cfb 18 0.13 6.77 1.69 5.00
118 INT200835 Gene_expression of Cd59a 5 0.77 9.02 1.64 5.00
119 INT179548 Gene_expression of C4b 17 0.58 9.88 1.62 5.00
120 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59 5.00
121 INT262293 Gene_expression of CC2D1A 21 0.40 44.64 1.5 5.00
122 INT182514 Binding of AGTR1 18 0.47 13.35 1.48 5.00
123 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47 5.00
124 INT179539 Positive_regulation of Gene_expression of C3 9 0.70 5.98 1.32 5.00
125 INT138843 Binding of CC2D1A 19 0.33 33.06 1.25 5.00
126 INT118131 Negative_regulation of C1s 10 0.07 2.92 1.15 5.00
127 INT179535 Negative_regulation of C1qa 10 0.57 4.7 1.03 5.00
128 INT184352 Positive_regulation of Cr2 6 0.42 2.81 0.96 5.00
129 INT184665 Positive_regulation of C4b 7 0.28 5.84 0.9 5.00
130 INT254143 Negative_regulation of CC2D1A 10 0.35 13.81 0.82 5.00
131 INT21246 Negative_regulation of ATP1A4 3 0.10 3.3 0.79 5.00
132 INT220888 Negative_regulation of Arhgap4 5 0.42 2.19 0.78 5.00
133 INT184341 Negative_regulation of C4b 12 0.50 7.66 0.75 5.00
134 INT200531 Gene_expression of Tnni1 8 0.58 4.68 0.75 5.00
135 INT94442 Gene_expression of Tcf21 2 0.25 2.32 0.72 5.00
136 INT179530 Transcription of C3 4 0.69 2.59 0.7 5.00
137 INT177557 Positive_regulation of Calr 12 0.48 5.47 0.61 5.00
138 INT279499 Negative_regulation of Tnni1 5 0.57 4.35 0.53 5.00
139 INT68701 Positive_regulation of C4bp 7 0.67 3.02 0.46 5.00
140 INT318301 Negative_regulation of DHODH 1 0.03 0.6 0.44 5.00
141 INT283239 Negative_regulation of Localization of CC2D1A 1 0.29 10.4 0.41 5.00
142 INT220894 Positive_regulation of C3ar1 4 0.09 3.75 0.41 5.00
143 INT229392 Negative_regulation of Positive_regulation of MPO 2 0.20 2.18 0.32 5.00
144 INT262297 Negative_regulation of Gene_expression of CC2D1A 2 0.25 2.95 0.31 5.00
145 INT131301 Binding of Serping1 3 0.28 1.86 0.3 5.00
146 INT102114 Negative_regulation of Chkb 6 0.39 2.05 0.28 5.00
147 INT177548 Regulation of Tpr 9 0.01 3.87 0.26 5.00
148 INT283235 Localization of KCNAB2 1 0.02 0.94 0.26 5.00
149 INT283232 Negative_regulation of Localization of KCNAB2 1 0.01 0.95 0.26 5.00
150 INT279445 Binding of C7 2 0.23 0.85 0.25 5.00
151 INT279440 Binding of C6 2 0.22 0.85 0.25 5.00
152 INT236354 Negative_regulation of Negative_regulation of C3 2 0.25 2.19 0.21 5.00
153 INT279464 Regulation of Chkb 2 0.20 1.48 0.21 5.00
154 INT244789 Positive_regulation of Cdca3 2 0.04 1.41 0.2 5.00
155 INT262295 Regulation of CC2D1A 3 0.27 5.38 0.19 5.00
156 INT180525 Regulation of LCN2 4 0.54 4.37 0.18 5.00
157 INT220895 Negative_regulation of Binding of C3 3 0.28 0.95 0.16 5.00
158 INT177555 Regulation of Gene_expression of Calr 3 0.28 0.82 0.16 5.00
159 INT244793 Gene_expression of Cdca3 2 0.12 1.38 0.16 5.00
160 INT283236 Regulation of ATN1 1 0.09 1.67 0.14 5.00
161 INT177554 Positive_regulation of Gene_expression of Calr 3 0.37 1.08 0.14 5.00
162 INT279448 Binding of Cdca3 1 0.05 0.32 0.12 5.00
163 INT279439 Binding of C1s 2 0.11 0.39 0.11 5.00
164 INT262294 Positive_regulation of Gene_expression of CC2D1A 2 0.30 2.74 0.09 5.00
165 INT279438 Negative_regulation of Localization of Ltf 1 0.09 0.35 0.08 5.00
166 INT283234 Positive_regulation of Protein_catabolism of CC2D1A 1 0.30 1.77 0.07 5.00
167 INT318300 Binding of CD52 1 0.10 1.16 0.07 5.00
168 INT283238 Negative_regulation of Negative_regulation of CC2D1A 1 0.25 2.4 0.05 5.00
169 INT283237 Protein_catabolism of CC2D1A 1 0.52 1.7 0.05 5.00
170 INT283240 Regulation of Binding of CC2D1A 1 0.31 2.21 0.05 5.00
171 INT283233 Regulation of Regulation of EDNRA 1 0.04 2.22 0.05 5.00
172 INT279470 Positive_regulation of Gene_expression of Cdca3 1 0.05 1.33 0.04 5.00
173 INT279452 Negative_regulation of Negative_regulation of Serping1 1 0.06 0.3 0.03 5.00
174 INT279442 Negative_regulation of Protein_catabolism of Hc 1 0.04 0 0 5.00
175 INT279447 Negative_regulation of Binding of Arhgap4 1 0.02 0 0 5.00
176 INT279467 Binding of Nxnl1 1 0.01 0 0 5.00
177 INT279454 Negative_regulation of C1ra 1 0.09 0 0 5.00
178 INT279469 Negative_regulation of Binding of Hc 1 0.05 0 0 5.00
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