D:Glucagonoma

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pChart

Disease Term
Synonyms Adenoma Alpha Cell, Adenomas Alpha Cell, Alpha Cell Adenoma, Alpha Cell Adenomas, Alpha Cell Tumor, Alpha Cell Tumors, Glucagonomas, Tumor Alpha Cell, Tumors Alpha Cell
Documents 40
Hot Single Events 21
Hot Interactions 3

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glucagonoma. They are ordered first by their relevance to Glucagonoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT30905 SST Negative_regulation of Localization of GCG 2 0.12 1.56 1.04 99.04
2 INT75283 SST Negative_regulation of Localization of INS 2 0.47 1.45 0.96 99.04
3 INT303656 SST Negative_regulation of Localization of GAST 1 0.12 1.45 0.82 99.04
4 INT303655 Positive_regulation of Binding of IGF1 and SSTR1 1 0.16 2.19 0.41 7.76
5 INT303650 Binding of IGF1 and SSTR1 1 0.12 2.17 0.4 6.32
6 INT303652 Binding of SST and SSTR2 1 0.26 0.46 0.57 5.00
7 INT303654 Binding of SST and SSTR5 1 0.22 0.46 0.57 5.00
8 INT303653 Binding of DRD2 and SST 1 0.18 0.45 0.54 5.00
9 INT303651 Binding of SSTR2 and SSTR5 1 0.24 0.23 0.45 5.00
10 INT303659 SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16 5.00
11 INT303657 Gene_expression of SSTR2 Negative_regulation of Gene_expression of SST 1 0.30 0.94 0.16 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glucagonoma. They are ordered first by their pain relevance and then by number of times they were reported in Glucagonoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140542 Gene_expression of SSTR2 18 0.65 13.58 3.94 99.98
2 INT127432 Gene_expression of Nup62 20 0.71 11.01 0.71 99.28
3 INT124407 Gene_expression of SSTR1 4 0.55 5.55 1.41 99.06
4 INT397 Localization of SST 232 0.81 58.05 101.19 99.04
5 INT243480 Gene_expression of SSTR5 1 0.55 4.25 0.85 98.96
6 INT41555 Gene_expression of GRN 8 0.52 10.94 0.69 98.92
7 INT138872 Gene_expression of SPINK5 21 0.58 30.11 4.12 98.76
8 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 98.54
9 INT252 Localization of GH1 529 0.80 227.4 122.05 97.12
10 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 93.76
11 INT812 Localization of INS 1026 0.81 515.6 145.31 93.28
12 INT17625 Localization of GCG 210 0.80 55.69 24.97 93.28
13 INT2243 Localization of GAST 67 0.81 34.54 16.19 93.28
14 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35 92.64
15 INT44783 Gene_expression of Chga 3 0.75 1.72 1.45 92.64
16 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 92.64
17 INT1634 Gene_expression of Gcg 25 0.75 14.98 4.42 87.76
18 INT303676 Regulation of Gene_expression of SSTR5 1 0.32 1.69 0.28 87.36
19 INT7412 Positive_regulation of SST 71 0.70 24.44 29.48 83.08
20 INT127433 Negative_regulation of Gene_expression of Nup62 2 0.53 2.36 0.08 82.28
21 INT691 Binding of SST 67 0.48 24.66 32.67 81.96
22 INT30629 Regulation of Positive_regulation of SST 2 0.37 1.35 0.59 78.88
23 INT303677 Positive_regulation of SSTR2 1 0.42 0.56 0.16 78.76
24 INT303668 Positive_regulation of Gene_expression of SSTR2 1 0.42 0.66 0.16 78.76
25 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 78.36
26 INT67195 Negative_regulation of Gene_expression of SST 7 0.42 6.98 4.88 78.36
27 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 78.08
28 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 76.48
29 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 76.48
30 INT303649 Gene_expression of Ptprf 1 0.58 0.96 0.11 75.36
31 INT14930 Regulation of Gene_expression of SST 12 0.45 6.86 3.89 70.88
32 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 67.92
33 INT3395 Negative_regulation of VIP 15 0.59 4.23 5.62 67.48
34 INT303680 Negative_regulation of Positive_regulation of VIP 1 0.15 1.2 0.28 67.48
35 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 66.72
36 INT216011 Regulation of TSC2 2 0.26 3.31 0 53.04
37 INT177938 Negative_regulation of NF1 9 0.43 10.3 0.2 51.60
38 INT4494 Regulation of GCG 41 0.45 18.38 9.68 48.96
39 INT303671 Negative_regulation of Regulation of GCG 1 0.13 1.44 0.22 48.96
40 INT14681 Negative_regulation of GCG 31 0.57 13.55 4.98 47.44
41 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 46.64
42 INT158 Localization of Prl 2431 0.81 378.96 952.2 46.20
43 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 39.92
44 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 37.04
45 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48 36.64
46 INT1893 Localization of Gh 1041 0.79 340.23 256.58 36.52
47 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 30.48
48 INT303672 Negative_regulation of Gene_expression of SSTR2 1 0.49 0.95 0.21 21.00
49 INT49769 Binding of SSTR2 4 0.48 1.39 2.14 20.88
50 INT5118 Regulation of SST 97 0.62 34.35 51.74 20.72
51 INT144461 Negative_regulation of SSTR2 2 0.49 1.03 0.98 15.32
52 INT243477 Binding of SSTR1 3 0.26 3.49 0.65 6.32
53 INT986 Negative_regulation of Localization of GHRH 16 0.58 8.57 3.16 5.28
54 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
55 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
56 INT249 Localization of GHRH 215 0.80 78.02 51.87 5.00
57 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
58 INT30 Gene_expression of Gast 158 0.78 99 41.45 5.00
59 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
60 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
61 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
62 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75 5.00
63 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
64 INT28642 Gene_expression of CXCR2 60 0.78 38.69 18.11 5.00
65 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46 5.00
66 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 5.00
67 INT63773 Gene_expression of DRD2 25 0.78 10.41 10.8 5.00
68 INT65058 Binding of Nfkb1 36 0.45 19.87 10.02 5.00
69 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 5.00
70 INT24724 Positive_regulation of Gene_expression of SST 11 0.67 7.51 6.12 5.00
71 INT13733 Localization of SSTR1 8 0.65 3.11 2.49 5.00
72 INT16964 Binding of IFNG 27 0.48 14.31 2.45 5.00
73 INT212466 Regulation of EPHB1 7 0.37 5.72 1.42 5.00
74 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 5.00
75 INT303667 Regulation of BCL2L11 3 0.16 1.03 1.21 5.00
76 INT219879 Positive_regulation of SPINK5 4 0.30 7.64 1.16 5.00
77 INT118350 Negative_regulation of Chga 2 0.42 1.64 0.71 5.00
78 INT246036 Positive_regulation of GRN 3 0.17 2.04 0.69 5.00
79 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 5.00
80 INT300623 Positive_regulation of Men1 1 0.35 10.65 0.57 5.00
81 INT202187 Regulation of GRN 3 0.09 1.47 0.53 5.00
82 INT303669 Regulation of SPINK5 1 0.24 0.65 0.53 5.00
83 INT300621 Localization of Men1 1 0.56 4.63 0.52 5.00
84 INT303674 Positive_regulation of Regulation of BCL2L11 1 0.02 0.28 0.5 5.00
85 INT246502 Negative_regulation of Men1 2 0.30 8.9 0.33 5.00
86 INT303673 Gene_expression of C10orf81 1 0.01 0.58 0.24 5.00
87 INT158763 Binding of GRN 3 0.36 0.94 0.2 5.00
88 INT274731 Binding of EPHB1 3 0.22 0.76 0.2 5.00
89 INT303678 Regulation of Gene_expression of SSTR1 1 0.19 0.84 0.18 5.00
90 INT240786 Binding of Bcl2a1c 10 0.18 9.47 0.12 5.00
91 INT240787 Positive_regulation of Bcl2a1c 12 0.22 9.79 0.06 5.00
92 INT300622 Binding of Jund 1 0.04 1.57 0 5.00
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