D:Glycogen Storage Disease

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Disease Term
Synonyms DISEASE GLYCOGEN STORAGE, Diseases Glycogen Storage, GLYCOGEN STORAGE DISEASES, Glycogen Storage Disorder, GLYCOGENOSES, GLYCOGENOSIS, Gsd Glycogen Storage Disease, MCARDLE DISEASE, Storage Disease Glycogen, Storage Diseases Glycogen, Thesaurosis
Documents 78
Hot Single Events 48
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Glycogen Storage Disease. They are ordered first by their relevance to Glycogen Storage Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT111380 Musk Negative_regulation of Phka2 1 0.03 0.92 0.19 99.64
2 INT248765 Binding of RUNX1 and CSF2 1 0.02 1.36 0 50.00
3 INT298081 Binding of OVGP1 and Ggt5 1 0.01 0 0 50.00
4 INT298082 Regulation of Binding of OVGP1 and Ggt5 1 0.01 0 0 50.00
5 INT175767 IL1B Regulation of Mtpn 1 0.00 0.06 0 45.88
6 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19 45.08
7 INT279361 Binding of TNF and KLF1 4 0.00 3.72 2.19 5.00
8 INT279359 Binding of ADA and TNF 1 0.20 2.61 1.91 5.00
9 INT279360 ADA Negative_regulation of Gene_expression of IFNG 1 0.06 0.51 0.44 5.00
10 INT279369 Binding of ADA and Ifx 1 0.29 0.27 0.35 5.00
11 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
12 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
13 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
14 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
15 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
16 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
17 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
18 INT287613 Binding of Fmr1 and Cysltr1 1 0.01 0.18 0.04 5.00
19 INT287620 Fmr1 Regulation of Gene_expression of Fxr2 1 0.43 0 0 5.00
20 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 0.05 0.06 0 5.00
21 INT312956 Regulation of Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
22 INT287612 Binding of Fmr1 and Dnajc13 1 0.01 0.84 0 5.00
23 INT175732 Binding of ARNTL and ARMC9 1 0.02 0.06 0 5.00
24 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
25 INT340379 Binding of Rabep1 and Ocrl 1 0.08 0.62 0 5.00
26 INT340380 Binding of Cfl1 and Clcn4-2 1 0.13 0.82 0 5.00
27 INT287606 Binding of Fxr1 and Fxr2 1 0.32 0 0 5.00
28 INT287605 Binding of Fmr1 and Kdm5d 1 0.01 0 0 5.00
29 INT287610 Binding of Fmr1 and Fxr1 1 0.46 0 0 5.00
30 INT287616 Ap3b1 Regulation of Binding of Fmr1 1 0.01 0 0 5.00
31 INT175729 Binding of ARNTL and PER1 1 0.19 0.07 0 5.00
32 INT287611 Fmr1 Regulation of Gene_expression of Fxr1 1 0.38 0 0 5.00
33 INT175730 Binding of CLOCK and ARMC9 1 0.02 0.06 0 5.00
34 INT287615 Ap3b1 Regulation of Binding of Fxr1 1 0.00 0 0 5.00
35 INT312955 Binding of MOCS1 and MTTP 1 0.00 0.21 0 5.00
36 INT287617 Ap3b1 Regulation of Fxr1 1 0.00 0 0 5.00
37 INT340378 Binding of Cfl1 and Clcn5 1 0.15 0.82 0 5.00
38 INT175728 Binding of PER1 and CLOCK 1 0.18 0.07 0 5.00
39 INT287619 Fmr1 Regulation of Dlg4 1 0.12 0.06 0 5.00
40 INT287614 Fxr2 Regulation of Gene_expression of Fxr1 1 0.24 0 0 5.00
41 INT287608 Binding of Fmr1 and Fxr2 1 0.52 0 0 5.00
42 INT340377 Binding of Clcn4-2 and Clcn5 1 0.35 0.82 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Glycogen Storage Disease. They are ordered first by their pain relevance and then by number of times they were reported in Glycogen Storage Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115475 Negative_regulation of RUNX1 4 0.37 5 0.22 99.82
2 INT98609 Negative_regulation of PYGM 11 0.43 6.21 0.6 99.78
3 INT261265 Gene_expression of PYGM 2 0.17 1.96 0.24 99.78
4 INT111379 Negative_regulation of Phka2 1 0.41 0.92 0.19 99.64
5 INT5262 Positive_regulation of AGL 14 0.40 7.51 0.65 99.56
6 INT120175 Negative_regulation of HK1 10 0.57 2.57 0.92 99.24
7 INT120174 Negative_regulation of Phosphorylation of HK1 2 0.11 0.79 0.2 99.24
8 INT57767 Gene_expression of HK1 17 0.30 9.72 3.22 99.24
9 INT76925 Negative_regulation of G6pc 6 0.57 2.9 1.25 99.20
10 INT16940 Protein_catabolism of AGL 4 0.39 2.94 0.14 99.12
11 INT211753 Negative_regulation of ACADS 1 0.03 1.49 0.08 99.10
12 INT120176 Phosphorylation of HK1 2 0.15 0.79 0.2 98.94
13 INT63222 Negative_regulation of MGAM 8 0.43 4.33 0.37 98.94
14 INT248772 Negative_regulation of Binding of CSF2 4 0.39 5.16 0.19 98.92
15 INT248769 Negative_regulation of Binding of CSF3 1 0.28 1.56 0 98.92
16 INT28320 Negative_regulation of Abo 16 0.58 5.69 4.7 98.88
17 INT188755 Positive_regulation of Binding of CSF2 6 0.44 8.79 0.35 98.76
18 INT14301 Binding of CSF2 82 0.48 67.95 8.98 98.76
19 INT46305 Negative_regulation of GAA 2 0.57 1.17 0.07 98.68
20 INT248767 Positive_regulation of Binding of CSF3 1 0.33 3.11 0 98.48
21 INT14302 Binding of CSF3 6 0.33 3.09 0.09 98.48
22 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03 98.34
23 INT107776 Negative_regulation of Phosphorylation of AGL 1 0.37 0.99 0.09 98.34
24 INT2936 Gene_expression of AGL 36 0.49 9.55 3.63 98.24
25 INT248768 Localization of SET 3 0.44 2.38 0.17 98.14
26 INT249052 Protein_catabolism of SMN1 1 0.02 1.98 0.1 98.00
27 INT107777 Phosphorylation of AGL 3 0.54 2.45 0.09 97.92
28 INT248771 Localization of IGKV6-21 1 0.01 2.24 0.08 97.74
29 INT90243 Regulation of MYOG 3 0.17 2.19 0.29 96.84
30 INT56160 Binding of Ifx 14 0.36 11.39 5.74 96.28
31 INT231205 Negative_regulation of Binding of Hcm 1 0.03 0.87 0.04 95.52
32 INT132662 Binding of Hcm 11 0.31 14.41 0.73 94.92
33 INT204463 Gene_expression of Fmr1 50 0.78 23.73 0.78 93.48
34 INT204460 Positive_regulation of Gene_expression of Fmr1 7 0.61 6.19 0.03 93.48
35 INT151538 Positive_regulation of Fmr1 21 0.68 12.24 2.07 93.16
36 INT90242 Positive_regulation of MYOG 4 0.34 1.46 0.22 90.28
37 INT151543 Binding of Fmr1 56 0.48 19.4 1.65 88.52
38 INT151539 Negative_regulation of Fmr1 9 0.59 11.85 0.87 88.08
39 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 86.92
40 INT153679 Regulation of AGL 4 0.04 1.49 0.07 82.68
41 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 82.48
42 INT151540 Regulation of Fmr1 8 0.59 6.08 1.34 81.92
43 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 81.52
44 INT231221 Gene_expression of Prkag2 1 0.07 0.94 0.03 81.40
45 INT50446 Binding of MRGPRF 3 0.31 3.05 0.08 81.32
46 INT101542 Positive_regulation of RRAD 6 0.44 5.34 0.42 81.04
47 INT231222 Gene_expression of Lamp2 1 0.07 0.93 0.03 80.96
48 INT230194 Negative_regulation of Gene_expression of PISRT1 1 0.30 0.81 0 80.80
49 INT23118 Positive_regulation of Gene_expression of AGL 4 0.30 1.74 0.54 80.00
50 INT230200 Gene_expression of PISRT1 1 0.53 0.8 0 79.68
51 INT175753 Negative_regulation of Gene_expression of RRAD 1 0.31 1.16 0.05 75.84
52 INT175763 Positive_regulation of Gene_expression of RRAD 1 0.50 1.16 0.05 75.04
53 INT175750 Gene_expression of RRAD 3 0.56 2.19 0.05 75.04
54 INT49706 Positive_regulation of TNNT2 22 0.69 12.65 1.56 75.00
55 INT5261 Localization of AGL 10 0.36 3.17 0.61 75.00
56 INT67258 Positive_regulation of Positive_regulation of AGL 1 0.00 1 0.08 75.00
57 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 75.00
58 INT201155 Regulation of Jph2 2 0.37 1.13 0.05 74.88
59 INT80667 Gene_expression of PFKM 4 0.57 2.13 0.07 71.88
60 INT124714 Localization of PFKM 2 0.37 1.45 0.21 71.44
61 INT137153 Positive_regulation of VIS1 2 0.04 1.52 0.31 71.16
62 INT204468 Negative_regulation of Gene_expression of Fmr1 5 0.59 7.5 0.19 67.72
63 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 62.88
64 INT312966 Regulation of Gene_expression of AGL 1 0.03 0.27 0 61.16
65 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 58.92
66 INT204443 Gene_expression of Fxr2 2 0.73 1.13 0.03 58.56
67 INT287569 Positive_regulation of Gene_expression of Fxr2 1 0.47 0.61 0 58.56
68 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 50.00
69 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 50.00
70 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 50.00
71 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 50.00
72 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 50.00
73 INT102658 Negative_regulation of Gene_expression of CSF2 42 0.50 38.63 8.32 50.00
74 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 50.00
75 INT4464 Localization of CEL 21 0.80 8.09 3.88 50.00
76 INT242978 Positive_regulation of OVGP1 7 0.28 3.57 1.81 50.00
77 INT112645 Negative_regulation of OVGP1 7 0.33 3.17 1.34 50.00
78 INT79748 Positive_regulation of RUNX1 3 0.03 1.28 1.08 50.00
79 INT1267 Regulation of G6PC 3 0.44 1.39 0.98 50.00
80 INT129934 Gene_expression of G6PC 3 0.57 5.3 0.35 50.00
81 INT14046 Negative_regulation of Ggt5 3 0.18 0.08 0.15 50.00
82 INT134224 Gene_expression of FLI1 3 0.53 1.79 0.14 50.00
83 INT255536 Gene_expression of OVGP1 3 0.65 0.81 0.09 50.00
84 INT248770 Positive_regulation of Gene_expression of FLI1 1 0.02 0.67 0 50.00
85 INT298077 Positive_regulation of Gene_expression of OVGP1 1 0.08 0 0 50.00
86 INT298079 Positive_regulation of Ggt5 1 0.07 0 0 50.00
87 INT298078 Localization of OVGP1 1 0.11 0.33 0 50.00
88 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 49.04
89 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 48.48
90 INT36915 Gene_expression of Neo1 39 0.36 7.28 1.31 48.32
91 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 48.24
92 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 47.12
93 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 47.12
94 INT57699 Positive_regulation of CD1A 11 0.50 8.49 2.93 47.12
95 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 47.12
96 INT175744 Regulation of GPD2 1 0.29 0.39 0.04 42.32
97 INT175745 Regulation of Negative_regulation of GPD2 1 0.29 0.39 0.04 42.32
98 INT103910 Binding of NOD2 19 0.47 12.24 2.93 40.72
99 INT175746 Negative_regulation of GPD2 1 0.27 0.37 0.04 36.80
100 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 34.08
101 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 32.72
102 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 32.72
103 INT175710 Regulation of Slc37a4 2 0.26 1.03 0.35 30.96
104 INT175752 Regulation of SLC37A4 1 0.17 0.36 0.04 30.96
105 INT103909 Gene_expression of NOD2 37 0.77 21.9 7.36 29.44
106 INT54527 Negative_regulation of Ap3b1 3 0.01 1.24 0.89 27.12
107 INT211198 Localization of SERPINH1 2 0.66 4.33 1.25 24.84
108 INT22834 Negative_regulation of CYP21A2 28 0.58 23.07 7.13 24.08
109 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 23.28
110 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 21.16
111 INT287587 Regulation of Negative_regulation of Fmr1 1 0.45 0.46 0.05 19.32
112 INT175765 Positive_regulation of NR4A3 2 0.45 0.11 0.03 17.80
113 INT204466 Negative_regulation of Regulation of Fmr1 2 0.43 0.97 0.08 13.40
114 INT175760 Gene_expression of CRY1 1 0.57 0 0 10.52
115 INT287573 Negative_regulation of Binding of Mex3c 1 0.01 0.15 0 8.48
116 INT287580 Binding of Mex3c 1 0.00 0.29 0 8.48
117 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 6.52
118 INT230196 Positive_regulation of Transcription of PISRT1 1 0.34 0.4 0 5.04
119 INT230193 Transcription of PISRT1 1 0.49 0.4 0 5.04
120 INT230199 Regulation of Transcription of PISRT1 1 0.19 0.4 0 5.04
121 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
122 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
123 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
124 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
125 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
126 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
127 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
128 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 5.00
129 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
130 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
131 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
132 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
133 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
134 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
135 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
136 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
137 INT1197 Negative_regulation of Localization of POMC 109 0.59 28.29 48.02 5.00
138 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
139 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
140 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 5.00
141 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 5.00
142 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
143 INT33768 Positive_regulation of Cysltr1 87 0.46 54.66 33.52 5.00
144 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
145 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
146 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 5.00
147 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
148 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
149 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 5.00
150 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
151 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 5.00
152 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
153 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
154 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
155 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
156 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
157 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
158 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 5.00
159 INT14587 Positive_regulation of Cl 44 0.20 20.37 16.72 5.00
160 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
161 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 5.00
162 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 5.00
163 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
164 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 5.00
165 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
166 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 5.00
167 INT33358 Gene_expression of Cysltr1 46 0.62 24.18 13.36 5.00
168 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 5.00
169 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 5.00
170 INT70050 Negative_regulation of IL10 56 0.58 37.45 12.39 5.00
171 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 5.00
172 INT4047 Binding of F13A1 105 0.43 66.54 11.81 5.00
173 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 5.00
174 INT93129 Negative_regulation of KCNH2 42 0.54 9.63 10.85 5.00
175 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01 5.00
176 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 5.00
177 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 5.00
178 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
179 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
180 INT73497 Regulation of IL10 33 0.45 22.6 9.19 5.00
181 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 5.00
182 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
183 INT7813 Regulation of SRI 25 0.61 6.18 8.13 5.00
184 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 5.00
185 INT116163 Gene_expression of S1pr1 29 0.78 14.11 7.27 5.00
186 INT17041 Gene_expression of PER1 24 0.66 5.31 7.12 5.00
187 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 5.00
188 INT28424 Regulation of Cysltr1 17 0.41 7.33 6.34 5.00
189 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
190 INT86600 Gene_expression of KCNH2 37 0.78 14.88 6.14 5.00
191 INT26181 Positive_regulation of Negative_regulation of POMC 12 0.70 1.03 6.14 5.00
192 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 5.00
193 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63 5.00
194 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.00
195 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 5.00
196 INT89104 Binding of TGFB1 29 0.44 13.67 5.12 5.00
197 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09 5.00
198 INT142162 Binding of IL10 30 0.37 21.9 4.84 5.00
199 INT4146 Binding of SHBG 49 0.47 31 4.71 5.00
200 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
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