D:Guillain-barre Syndrome

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Disease Term
Synonyms ACUTE AUTOIMMUNE NEUROPATHIES, Acute Autoimmune Neuropathy, Acute Inflammatory Demyelinating Polyradiculoneuropathy, Acute Inflammatory Polyneuropathies, Acute Inflammatory Polyneuropathy, Acute Inflammatory Polyradiculoneuropathies, Acute Inflammatory Polyradiculoneuropathy, Aidp, Autoimmune Neuropathies Acute, AUTOIMMUNE NEUROPATHY ACUTE, Demyelinating Polyradiculoneuropathy Acute Inflammatory
Documents 49
Hot Single Events 22
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Guillain-barre Syndrome. They are ordered first by their relevance to Guillain-barre Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT352627 Binding of IGHG3 and MAN2A1 1 0.00 1.48 0 55.44
2 INT149743 Ean5 Positive_regulation of Gene_expression of P2rx2 1 0.10 1.54 1.5 36.44
3 INT282129 Il10 Positive_regulation of Icam1 1 0.56 3.12 0.82 5.00
4 INT282128 Gene_expression of Il10 Positive_regulation of Positive_regulation of Icam1 1 0.37 1.12 0.28 5.00
5 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
6 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Guillain-barre Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Guillain-barre Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT209033 Positive_regulation of Localization of IFN1@ 27 0.67 12.55 2.84 100.00
2 INT170754 Localization of IFN1@ 121 0.78 66.78 15.6 99.70
3 INT352629 Binding of MAN2A1 1 0.05 4.16 0.23 99.60
4 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.82
5 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 98.82
6 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 98.76
7 INT297115 Gene_expression of TEX33 3 0.01 5.37 1.86 98.72
8 INT297113 Positive_regulation of Gene_expression of TEX33 2 0.01 3.87 1.14 98.72
9 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.62
10 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 98.00
11 INT170755 Positive_regulation of Positive_regulation of IFN1@ 17 0.67 8.72 3.65 96.08
12 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 95.04
13 INT119446 Positive_regulation of Gnb5 6 0.58 6.47 3.72 94.16
14 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 93.92
15 INT94335 Positive_regulation of CXCL10 71 0.58 50.69 23 93.92
16 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 90.64
17 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 87.12
18 INT69282 Binding of PHEX 4 0.15 1.43 0.41 87.12
19 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 87.12
20 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 86.52
21 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 81.20
22 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 81.20
23 INT352628 Negative_regulation of MAN2A1 1 0.05 1.52 0 79.80
24 INT297111 Regulation of Transcription of PRDM1 1 0.44 0.41 0.08 79.56
25 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 79.56
26 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 79.44
27 INT276368 Gene_expression of PRDM1 2 0.75 1.4 0.13 78.64
28 INT297112 Transcription of PRDM1 1 0.69 0.41 0.07 78.64
29 INT297114 Positive_regulation of Transcription of PRDM1 1 0.45 0.41 0.07 78.64
30 INT276356 Positive_regulation of PRDM1 4 0.49 2.07 0.14 78.20
31 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 76.12
32 INT260875 Binding of HLA-DRB2 2 0.01 1.33 0.4 72.64
33 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 70.32
34 INT62960 Gene_expression of P2rx2 149 0.77 58.31 59.16 68.04
35 INT297067 Positive_regulation of RT1@ 1 0.03 0.93 0.28 65.04
36 INT12501 Positive_regulation of Adarb1 166 0.58 36.94 118.92 62.48
37 INT12161 Positive_regulation of P2rx2 70 0.69 34.22 34.4 60.96
38 INT116705 Positive_regulation of Positive_regulation of P2rx2 13 0.49 9.44 9.47 60.96
39 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 59.84
40 INT103230 Gene_expression of Btnl2 17 0.75 8.55 4.77 59.84
41 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 49.76
42 INT144613 Regulation of NEFL 2 0.31 1.55 0.07 49.76
43 INT286054 Regulation of GJB1 1 0.08 1.04 0.07 49.76
44 INT6868 Gene_expression of GFAP 136 0.78 84.65 22.7 42.24
45 INT52937 Gene_expression of Cd68 37 0.67 31.33 7.54 42.24
46 INT141024 Positive_regulation of TEX33 2 0.05 1.84 0.83 41.96
47 INT78234 Positive_regulation of Gene_expression of P2rx2 18 0.69 12.86 12.75 36.28
48 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 32.88
49 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 31.20
50 INT71768 Regulation of Gene_expression of Il10 27 0.62 19.17 10.4 31.20
51 INT282127 Regulation of Regulation of Best1 1 0.15 1.67 0.18 30.24
52 INT211972 Regulation of Best1 18 0.33 12.04 0.67 29.84
53 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 27.40
54 INT211968 Localization of Best1 11 0.40 9.33 0.38 27.00
55 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 19.64
56 INT305170 Gene_expression of Man2c1 1 0.05 1.89 0 18.88
57 INT112968 Negative_regulation of Gnb5 5 0.34 7.79 1.81 17.84
58 INT227759 Gene_expression of Best1 26 0.42 20.36 1.73 14.68
59 INT90792 Localization of Il10 144 0.80 87.88 30.03 12.64
60 INT305171 Binding of Man2c1 1 0.03 1.75 0 12.12
61 INT61316 Gene_expression of Coq10a 59 0.73 32.81 3.95 11.76
62 INT220701 Regulation of Negative_regulation of ACHE 2 0.25 1.06 0 11.04
63 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
64 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
65 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 5.00
66 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
67 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
68 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 5.00
69 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
70 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
71 INT9694 Positive_regulation of Csf2 102 0.68 70.09 33.07 5.00
72 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
73 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
74 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
75 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
76 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 5.00
77 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 5.00
78 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
79 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 5.00
80 INT62546 Positive_regulation of Gene_expression of Icam1 60 0.70 59.52 16.9 5.00
81 INT56447 Positive_regulation of Icam1 64 0.64 64.14 16.16 5.00
82 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
83 INT94051 Positive_regulation of Arg1 41 0.60 36.22 13.72 5.00
84 INT81629 Positive_regulation of Fas 58 0.70 59.63 12.94 5.00
85 INT10870 Regulation of IgG 67 0.59 43.27 12.74 5.00
86 INT93620 Positive_regulation of Gene_expression of Fasl 51 0.66 59.45 12.04 5.00
87 INT71769 Negative_regulation of Gene_expression of Il10 40 0.57 22.53 10.37 5.00
88 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 5.00
89 INT99942 Positive_regulation of Fasl 37 0.68 32.61 6.92 5.00
90 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
91 INT111262 Regulation of Gnb5 8 0.51 4.18 4.34 5.00
92 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 5.00
93 INT35683 Gene_expression of Gsr 24 0.46 16.94 3.6 5.00
94 INT78203 Gene_expression of PMP22 12 0.63 7.49 3.58 5.00
95 INT168677 Negative_regulation of ACOT1 14 0.27 6.29 3.52 5.00
96 INT66347 Gene_expression of MLL 29 0.65 14.82 3.18 5.00
97 INT88464 Negative_regulation of CST7 11 0.31 5.33 2.17 5.00
98 INT78202 Binding of GSTK1 17 0.31 5.44 1.66 5.00
99 INT102946 Regulation of Positive_regulation of IgG 3 0.12 3.16 1.24 5.00
100 INT37105 Binding of CHRNE 3 0.31 6.88 0.87 5.00
101 INT250351 Positive_regulation of Gene_expression of Best1 5 0.27 3.14 0.65 5.00
102 INT69283 Gene_expression of PHEX 25 0.75 7.81 0.64 5.00
103 INT78201 Regulation of MLL 2 0.02 0.79 0.48 5.00
104 INT15588 Regulation of PHEX 4 0.26 1.48 0.39 5.00
105 INT228540 Localization of Coq10a 12 0.63 3.5 0.3 5.00
106 INT166755 Localization of PHEX 2 0.73 1.16 0.28 5.00
107 INT220699 Positive_regulation of CHRNE 5 0.32 2.26 0.26 5.00
108 INT228545 Regulation of Coq10a 8 0.42 5.62 0.23 5.00
109 INT285702 Negative_regulation of Tpmt 2 0.28 1.4 0.19 5.00
110 INT219880 Binding of Ifna 6 0.11 2.58 0.15 5.00
111 INT37103 Gene_expression of CHRNE 5 0.67 4.32 0.12 5.00
112 INT220702 Protein_catabolism of CHRNE 1 0.64 1.22 0.08 5.00
113 INT220704 Protein_catabolism of ACOT1 1 0.02 1.19 0.08 5.00
114 INT220700 Gene_expression of MUSK 3 0.75 6.67 0.07 5.00
115 INT140176 Binding of Minute 2 0.08 0.36 0 5.00
116 INT288101 Regulation of Ifna 1 0.06 0.16 0 5.00
117 INT288100 Gene_expression of Minute 1 0.08 0.27 0 5.00
118 INT220703 Regulation of MUSK 1 0.34 1.48 0 5.00
119 INT305172 Phosphorylation of Gnb5 1 0.05 1.41 0 5.00
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