D:Habitual Abortion

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Disease Term
Synonyms Abortion Recurrent, Abortions Habitual, Abortions Recurrent, Habitual Abortions, Miscarriage Recurrent, MISCARRIAGES RECURRENT, Recurrent Abortion, RECURRENT ABORTIONS, RECURRENT MISCARRIAGE, RECURRENT MISCARRIAGES
Documents 64
Hot Single Events 30
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Habitual Abortion. They are ordered first by their relevance to Habitual Abortion and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT175246 Binding of F13A1 and SH2B2 1 0.00 2.24 0 96.20
2 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 30.60
3 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 5.00
4 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 5.00
5 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62 5.00
6 INT181471 Binding of Il10 and Ptbp1 1 0.05 2.14 0.58 5.00
7 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35 5.00
8 INT175330 IL6 Positive_regulation of Gene_expression of CYP19A1 1 0.01 0.97 0.32 5.00
9 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29 5.00
10 INT302468 INCENP Positive_regulation of Gene_expression of MMP9 1 0.01 0.72 0.26 5.00
11 INT175328 FASLG Positive_regulation of FAS 1 0.01 0.9 0.17 5.00
12 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 5.00
13 INT186243 IL36RN Positive_regulation of B4GALNT1 1 0.00 0.43 0.12 5.00
14 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 5.00
15 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1 5.00
16 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1 5.00
17 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1 5.00
18 INT186244 Binding of AGRP and ALB 1 0.03 0.53 0.1 5.00
19 INT330852 Fasl Positive_regulation of TRAT1 1 0.05 0.4 0.06 5.00
20 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03 5.00
21 INT201800 OLFM1 Regulation of EHF 1 0.05 0 0 5.00
22 INT186248 NR5A1 Positive_regulation of Transcription of STAR 1 0.01 0.21 0 5.00
23 INT186239 Binding of ROS1 and Positive_regulation of PDE2A 1 0.00 0 0 5.00
24 INT194924 CD22 Positive_regulation of PTPN6 1 0.05 0.08 0 5.00
25 INT186241 Gene_expression of ROS1 Positive_regulation of PDE2A 1 0.00 0 0 5.00
26 INT194926 Binding of CD40LG and Positive_regulation of BCR 1 0.04 0.39 0 5.00
27 INT201799 PGR Regulation of HSD17B2 1 0.12 0.08 0 5.00
28 INT194927 Binding of CD40LG and Positive_regulation of CD79B 1 0.01 0.4 0 5.00
29 INT186247 CGA Regulation of Gene_expression of SOD1 1 0.01 0.35 0 5.00
30 INT194925 Binding of CD22 and MLL2 1 0.08 0.18 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Habitual Abortion. They are ordered first by their pain relevance and then by number of times they were reported in Habitual Abortion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 99.92
2 INT9842 Binding of F2 36 0.47 22.79 4.42 99.80
3 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 98.80
4 INT181466 Binding of Mbl2 1 0.29 1.03 0.04 96.92
5 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 95.04
6 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 94.40
7 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 94.08
8 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13 93.64
9 INT195672 Localization of APC 7 0.74 3.76 0.3 93.08
10 INT181467 Gene_expression of Mbl2 1 0.53 2.3 0.14 93.08
11 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 93.04
12 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 93.04
13 INT69134 Positive_regulation of MPEG1 9 0.26 5.95 0.97 93.00
14 INT181477 Positive_regulation of MBL3P 1 0.08 1 0.04 92.96
15 INT181474 Gene_expression of MBL3P 1 0.12 1.1 0 92.72
16 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 91.52
17 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 91.52
18 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 91.36
19 INT58904 Localization of TH1L 40 0.68 27.11 10.52 91.32
20 INT330633 Gene_expression of PROS1 4 0.65 1.54 0.04 91.12
21 INT101481 Positive_regulation of Lep 81 0.69 62.59 9.95 90.92
22 INT174054 Positive_regulation of Gene_expression of Lep 25 0.69 21.3 3.72 90.92
23 INT101483 Gene_expression of Lep 159 0.78 104.77 25.12 90.24
24 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 88.80
25 INT349254 Negative_regulation of PROS1 1 0.42 1.24 0 88.56
26 INT173505 Localization of Hand2 63 0.57 45.32 13.66 87.80
27 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 87.72
28 INT89661 Gene_expression of Hrec 102 0.21 69.91 39.57 87.36
29 INT203272 Positive_regulation of Gvhd1 1 0.01 1.32 0.06 84.72
30 INT302483 Regulation of MAGT1 1 0.01 1.96 0.05 83.80
31 INT29561 Binding of GSTM1 35 0.48 25.86 6.24 79.72
32 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 78.96
33 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 78.96
34 INT132417 Transcription of ANXA5 2 0.59 1.82 0.95 78.56
35 INT130773 Regulation of Gene_expression of FAS 5 0.37 6.87 1.32 77.80
36 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77 75.84
37 INT259035 Localization of SH2B2 3 0.43 1.77 0.42 74.76
38 INT330850 Positive_regulation of TRAT1 1 0.05 0.54 0.15 73.08
39 INT12062 Positive_regulation of Gene_expression of OXTR 9 0.69 1.04 1.63 67.20
40 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69 66.80
41 INT302487 Negative_regulation of Gene_expression of OXTR 1 0.02 0.54 0.21 66.80
42 INT181475 Binding of MBL3P 1 0.06 1.06 0.12 66.72
43 INT181479 Positive_regulation of Binding of MBL3P 1 0.08 1.07 0.12 66.72
44 INT14447 Localization of F2 20 0.79 12.77 2.67 64.96
45 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 64.48
46 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 64.16
47 INT130 Negative_regulation of OXTR 19 0.43 4.63 4.96 64.00
48 INT181476 Negative_regulation of Binding of IFNG 1 0.01 1.18 0.08 61.88
49 INT90371 Localization of Hrec 28 0.05 19.11 10.12 61.60
50 INT90792 Localization of Il10 144 0.80 87.88 30.03 61.60
51 INT20379 Localization of Il4 85 0.73 51.22 20.55 61.60
52 INT69156 Localization of IL5 21 0.68 14.95 5.37 61.60
53 INT16964 Binding of IFNG 27 0.48 14.31 2.45 61.32
54 INT181469 Binding of Gas1 1 0.35 1.16 0.08 61.32
55 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63 60.64
56 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 59.80
57 INT237904 Negative_regulation of Localization of Hand1 5 0.24 3.52 1.09 59.76
58 INT330849 Negative_regulation of Localization of Hrec 1 0.00 0.45 0.21 59.76
59 INT10763 Localization of IL2 157 0.80 81.11 33.21 59.44
60 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 59.44
61 INT20378 Localization of Hand1 53 0.71 41.96 13.31 59.44
62 INT91667 Localization of IL12A 39 0.74 25.51 7.36 59.44
63 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 59.04
64 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 56.80
65 INT181470 Regulation of Transcription of Fas 1 0.28 1.25 0.15 53.80
66 INT94546 Transcription of Fas 13 0.56 6.99 0.88 53.44
67 INT20461 Binding of Esr1 34 0.48 9.58 3.66 51.68
68 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 50.72
69 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 50.72
70 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 50.44
71 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 50.12
72 INT115108 Negative_regulation of Gene_expression of FAS 9 0.57 9.16 1.23 46.60
73 INT80034 Positive_regulation of Gene_expression of FAS 32 0.67 30.34 8.51 46.20
74 INT181478 Negative_regulation of MBL3P 1 0.10 0.76 0.21 39.04
75 INT135803 Regulation of Gene_expression of Fasl 6 0.36 4.35 1.24 37.76
76 INT93626 Gene_expression of Fasl 118 0.75 115.24 25.11 37.08
77 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 36.80
78 INT35584 Binding of ACLY 22 0.35 31.78 7.17 33.56
79 INT65713 Localization of ICAM1 42 0.81 39.55 11.49 30.60
80 INT80549 Binding of ICAM1 53 0.47 42.76 9.72 30.60
81 INT91739 Positive_regulation of MYLK 9 0.54 2.89 1.58 29.72
82 INT87322 Binding of ITGAL 23 0.47 15.73 4.68 27.32
83 INT52740 Binding of ACLS 5 0.31 3 0.54 24.52
84 INT203867 Localization of BACE2 2 0.43 1.38 0.17 23.28
85 INT139982 Positive_regulation of BACE2 6 0.42 4.33 1.48 22.60
86 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 22.48
87 INT94784 Binding of ROS1 113 0.40 71.57 10.26 22.48
88 INT117330 Negative_regulation of Binding of ROS1 13 0.37 8.33 1.67 22.48
89 INT12082 Localization of IL6 365 0.81 241.78 105.78 19.80
90 INT50230 Positive_regulation of Localization of IL6 105 0.70 69.21 29.52 19.80
91 INT63340 Positive_regulation of Gene_expression of ICAM1 109 0.70 90.82 20.61 17.00
92 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 16.56
93 INT65712 Positive_regulation of Localization of ICAM1 14 0.70 16.72 5.5 13.20
94 INT156975 Gene_expression of SLEB1 31 0.65 38.83 6.73 10.24
95 INT11814 Positive_regulation of Alb 43 0.63 31.71 6.28 7.72
96 INT259029 Regulation of Phosphorylation of SH2B2 1 0.26 0.85 0.03 7.12
97 INT259040 Phosphorylation of SH2B2 1 0.47 0.85 0.03 5.76
98 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
99 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 5.00
100 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
101 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
102 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
103 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
104 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
105 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
106 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
107 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
108 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
109 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
110 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
111 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
112 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
113 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
114 INT1793 Localization of CGA 379 0.81 67.38 114.69 5.00
115 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
116 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
117 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
118 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
119 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
120 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
121 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 5.00
122 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
123 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
124 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
125 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
126 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 5.00
127 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
128 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
129 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 5.00
130 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 5.00
131 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
132 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
133 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
134 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
135 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
136 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
137 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
138 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
139 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 5.00
140 INT60695 Positive_regulation of Gene_expression of Il10 154 0.70 120.28 43.07 5.00
141 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
142 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
143 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 5.00
144 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
145 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
146 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
147 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
148 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
149 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
150 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 5.00
151 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
152 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
153 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 5.00
154 INT4727 Regulation of TAC1 60 0.47 6.74 32.83 5.00
155 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
156 INT7082 Gene_expression of CRH 180 0.78 64.66 31.74 5.00
157 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 5.00
158 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
159 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
160 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
161 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
162 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 5.00
163 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42 5.00
164 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
165 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
166 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
167 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 5.00
168 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 5.00
169 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
170 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
171 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 5.00
172 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
173 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 5.00
174 INT15796 Regulation of IL2 66 0.61 25.43 20.62 5.00
175 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
176 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
177 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
178 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 5.00
179 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86 5.00
180 INT69304 Negative_regulation of Il10 47 0.59 36.88 19.79 5.00
181 INT74286 Regulation of Il10 42 0.44 28.06 19.44 5.00
182 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19 5.00
183 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 5.00
184 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
185 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
186 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97 5.00
187 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
188 INT34057 Negative_regulation of Gene_expression of IFNA1 65 0.58 43.46 17.25 5.00
189 INT77620 Gene_expression of Fas 146 0.78 72.4 16.61 5.00
190 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
191 INT10000 Regulation of Gene_expression of IL2 56 0.45 15.33 16.2 5.00
192 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17 5.00
193 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 5.00
194 INT92354 Localization of ESR1 77 0.75 33.04 15.51 5.00
195 INT129 Localization of OXTR 51 0.80 11.08 15.36 5.00
196 INT106745 Localization of CRP 65 0.81 66.44 15.21 5.00
197 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 5.00
198 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 5.00
199 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 5.00
200 INT16919 Gene_expression of IL36RN 48 0.48 32.78 13.83 5.00
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