D:Hallux Valgus

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms BUNION, Bunions, HALLUX ABDUCTOVALGUS, METATARSUS PRIMUS VARUS, Primus Varus Metatarsus, Varus Metatarsus Primus
Documents 404
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hallux Valgus. They are ordered first by their relevance to Hallux Valgus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
2 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 5.00
3 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
4 INT322201 Binding of OAP and SLC34A1 1 0.01 1.49 0.77 5.00
5 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69 5.00
6 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35 5.00
7 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23 5.00
8 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18 5.00
9 INT290877 Binding of Bcl2a1c and Lepr 1 0.00 0.87 0.04 5.00
10 INT290861 MNT Positive_regulation of INS 1 0.03 1.78 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hallux Valgus. They are ordered first by their pain relevance and then by number of times they were reported in Hallux Valgus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT257935 Regulation of SHFM1 1 0.05 1.5 0.1 98.90
2 INT321921 Gene_expression of FEA 1 0.34 0.48 0 85.24
3 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 75.00
4 INT242911 Localization of Bcl2a1c 2 0.36 1.48 0.11 61.24
5 INT200465 Negative_regulation of Regulation of SERPINB6 1 0.35 1.37 0.25 59.44
6 INT200463 Regulation of SERPINB6 9 0.25 3.46 1.25 58.84
7 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 58.80
8 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 58.52
9 INT25087 Negative_regulation of FEA 3 0.37 0.28 0.99 50.00
10 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 46.60
11 INT229632 Binding of PADI4 21 0.48 37.45 0.34 46.04
12 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 40.88
13 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 40.80
14 INT242910 Positive_regulation of Positive_regulation of Bcl2a1c 2 0.05 2.24 0.06 34.60
15 INT240787 Positive_regulation of Bcl2a1c 12 0.22 9.79 0.06 33.56
16 INT114330 Binding of MPZ 21 0.32 25.58 2.14 25.92
17 INT200467 Binding of SERPINB6 2 0.30 0.14 0.31 25.36
18 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
19 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
20 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
21 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
22 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
23 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
24 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
25 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
26 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
27 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
28 INT10166 Localization of Tnf 237 0.81 153.95 88.64 5.00
29 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
30 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
31 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
32 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
33 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
34 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
35 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
36 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
37 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
38 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
39 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 5.00
40 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
41 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
42 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 5.00
43 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
44 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
45 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 5.00
46 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
47 INT14572 Binding of INS 205 0.48 175.43 13.38 5.00
48 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
49 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
50 INT144391 Gene_expression of RETN 42 0.75 40.48 10.47 5.00
51 INT4606 Regulation of Gene_expression of INS 67 0.61 54.69 7.53 5.00
52 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
53 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55 5.00
54 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 5.00
55 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 5.00
56 INT37811 Negative_regulation of SERPINB6 8 0.47 4.65 3.15 5.00
57 INT12642 Gene_expression of TRIM47 3 0.54 1.18 2.49 5.00
58 INT16964 Binding of IFNG 27 0.48 14.31 2.45 5.00
59 INT125138 Positive_regulation of RETN 13 0.67 11.94 2.34 5.00
60 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24 5.00
61 INT49082 Gene_expression of MPZ 15 0.65 31.26 2.24 5.00
62 INT164248 Positive_regulation of MPZ 18 0.67 24.54 2.16 5.00
63 INT37809 Gene_expression of SERPINB6 7 0.77 6.58 2.12 5.00
64 INT191534 Negative_regulation of EGFL7 10 0.06 7.52 1.98 5.00
65 INT131263 Negative_regulation of MPZ 12 0.49 7.11 1.94 5.00
66 INT37810 Positive_regulation of Negative_regulation of SERPINB6 2 0.41 1.84 1.78 5.00
67 INT142637 Positive_regulation of Gene_expression of PRTN3 8 0.46 6.23 1.75 5.00
68 INT155006 Regulation of RETN 9 0.45 7.31 1.7 5.00
69 INT171997 Gene_expression of ERAL1 5 0.25 4.97 1.67 5.00
70 INT93350 Binding of Lepr 17 0.05 27.21 1.5 5.00
71 INT93956 Binding of HBM 20 0.35 8.86 1.48 5.00
72 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 5.00
73 INT107541 Positive_regulation of MSD 7 0.43 5.41 1.45 5.00
74 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 5.00
75 INT155007 Positive_regulation of Gene_expression of RETN 4 0.27 9.17 1.3 5.00
76 INT79928 Positive_regulation of Localization of ALB 10 0.60 8.96 1.05 5.00
77 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 5.00
78 INT200462 Binding of IDS 13 0.31 4.95 1 5.00
79 INT153329 Gene_expression of Cm9 6 0.67 4.35 0.95 5.00
80 INT4681 Localization of RAPGEF5 12 0.68 8.69 0.93 5.00
81 INT97174 Positive_regulation of SERPINB6 5 0.50 3.74 0.91 5.00
82 INT191926 Negative_regulation of Lepr 13 0.48 17.68 0.8 5.00
83 INT246642 Binding of CLTCL1 3 0.17 1.32 0.63 5.00
84 INT69486 Negative_regulation of Bcl2a1c 34 0.10 19.03 0.6 5.00
85 INT47030 Negative_regulation of ARMC9 22 0.38 13.08 0.47 5.00
86 INT322202 Gene_expression of SLC34A1 1 0.04 1.01 0.45 5.00
87 INT11118 Gene_expression of RAPGEF5 13 0.65 9.35 0.43 5.00
88 INT227216 Binding of TRIM47 2 0.30 1.11 0.34 5.00
89 INT322203 Negative_regulation of TRIM47 1 0.34 0.56 0.28 5.00
90 INT200461 Negative_regulation of PHF13 1 0.01 0.67 0.23 5.00
91 INT214119 Regulation of Lepr 2 0.23 3.17 0.23 5.00
92 INT200466 Positive_regulation of Negative_regulation of MPZ 1 0.42 0.19 0.14 5.00
93 INT69485 Regulation of Bcl2a1c 14 0.34 9.99 0.13 5.00
94 INT240786 Binding of Bcl2a1c 10 0.18 9.47 0.12 5.00
95 INT283245 Gene_expression of MND1 2 0.11 1.94 0.07 5.00
96 INT241221 Localization of MBS1 1 0.40 0.09 0.04 5.00
97 INT176521 Positive_regulation of Lepr 8 0.07 6.6 0.03 5.00
98 INT200464 Localization of MPZ 3 0.63 3.83 0.03 5.00
99 INT290862 Regulation of Regulation of Lepr 1 0.00 1 0 5.00
100 INT334392 Regulation of PADI4 2 0.22 3.42 0 5.00
101 INT290870 Negative_regulation of MNT 1 0.05 1.61 0 5.00
102 INT322205 Gene_expression of CELIAC5 1 0.18 0.12 0 5.00
103 INT290871 Positive_regulation of MNT 1 0.06 1.05 0 5.00
104 INT350895 Transcription of PRTN3 2 0.58 0.15 0 5.00
105 INT241220 Gene_expression of MBS1 2 0.36 0.38 0 5.00
106 INT322204 Negative_regulation of CELIAC5 1 0.11 0.12 0 5.00
107 INT290869 Gene_expression of MNT 1 0.10 3.16 0 5.00
108 INT290866 Localization of MNT 1 0.11 0.6 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox