D:Hammer Toe Syndrome

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pChart

Disease Term
Synonyms CLAW TOE, Claw Toes, Clawtoe, Clawtoes, HAMMER TOE, Hammer Toes, Hammertoe Syndrome, HAMMERTOE SYNDROMES, MALLET TOE, Mallet Toes, Syndrome Hammer Toe
Documents 68
Hot Single Events 1
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hammer Toe Syndrome. They are ordered first by their relevance to Hammer Toe Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
2 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14 5.00
3 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
4 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69 5.00
5 INT334393 IL6 Positive_regulation of Tnf 1 0.16 1.41 0.35 5.00
6 INT334390 ADIPOQ Positive_regulation of Localization of INS 1 0.09 1.3 0.23 5.00
7 INT334394 ADIPOQ Negative_regulation of Gene_expression of Tnf 1 0.37 1.06 0.18 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hammer Toe Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Hammer Toe Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT17754 Negative_regulation of Vamp8 1 0.37 1.63 0.16 85.44
2 INT242911 Localization of Bcl2a1c 2 0.36 1.48 0.11 62.20
3 INT200465 Negative_regulation of Regulation of SERPINB6 1 0.35 1.37 0.25 58.68
4 INT200463 Regulation of SERPINB6 9 0.25 3.46 1.25 58.08
5 INT164512 Regulation of MPZ 12 0.30 8.38 1.53 57.76
6 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 55.68
7 INT10207 Gene_expression of PADI4 22 0.75 23.49 1.74 43.48
8 INT229632 Binding of PADI4 21 0.48 37.45 0.34 42.92
9 INT105993 Gene_expression of IDS 26 0.78 10.83 2.41 40.12
10 INT242910 Positive_regulation of Positive_regulation of Bcl2a1c 2 0.05 2.24 0.06 35.56
11 INT240787 Positive_regulation of Bcl2a1c 12 0.22 9.79 0.06 34.52
12 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 34.32
13 INT114330 Binding of MPZ 21 0.32 25.58 2.14 27.28
14 INT200467 Binding of SERPINB6 2 0.30 0.14 0.31 26.72
15 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
16 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
17 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
18 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
19 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
20 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
21 INT10166 Localization of Tnf 237 0.81 153.95 88.64 5.00
22 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
23 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
24 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 5.00
25 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 5.00
26 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
27 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
28 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
29 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
30 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 5.00
31 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 5.00
32 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 5.00
33 INT144391 Gene_expression of RETN 42 0.75 40.48 10.47 5.00
34 INT39712 Binding of pad 82 0.48 110.92 10.33 5.00
35 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
36 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 5.00
37 INT37811 Negative_regulation of SERPINB6 8 0.47 4.65 3.15 5.00
38 INT125138 Positive_regulation of RETN 13 0.67 11.94 2.34 5.00
39 INT49082 Gene_expression of MPZ 15 0.65 31.26 2.24 5.00
40 INT164248 Positive_regulation of MPZ 18 0.67 24.54 2.16 5.00
41 INT37809 Gene_expression of SERPINB6 7 0.77 6.58 2.12 5.00
42 INT131263 Negative_regulation of MPZ 12 0.49 7.11 1.94 5.00
43 INT37810 Positive_regulation of Negative_regulation of SERPINB6 2 0.41 1.84 1.78 5.00
44 INT155006 Regulation of RETN 9 0.45 7.31 1.7 5.00
45 INT171997 Gene_expression of ERAL1 5 0.25 4.97 1.67 5.00
46 INT188241 Negative_regulation of ADIPOQ 16 0.43 22.16 1.47 5.00
47 INT155007 Positive_regulation of Gene_expression of RETN 4 0.27 9.17 1.3 5.00
48 INT200462 Binding of IDS 13 0.31 4.95 1 5.00
49 INT97174 Positive_regulation of SERPINB6 5 0.50 3.74 0.91 5.00
50 INT200461 Negative_regulation of PHF13 1 0.01 0.67 0.23 5.00
51 INT200466 Positive_regulation of Negative_regulation of MPZ 1 0.42 0.19 0.14 5.00
52 INT240786 Binding of Bcl2a1c 10 0.18 9.47 0.12 5.00
53 INT241221 Localization of MBS1 1 0.40 0.09 0.04 5.00
54 INT200464 Localization of MPZ 3 0.63 3.83 0.03 5.00
55 INT241220 Gene_expression of MBS1 2 0.36 0.38 0 5.00
56 INT334392 Regulation of PADI4 2 0.22 3.42 0 5.00
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