D:Hashimoto Disease

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Disease Term
Synonyms Chronic Lymphocytic Thyroiditides, Chronic Lymphocytic Thyroiditis, DISEASE HASHIMOTO, Disease Hashimoto S, Hashimoto S Disease, Hashimoto Thyroiditides, Hashimoto Thyroiditis, HASHIMOTOS DISEASE, Lymphocytic Thyroiditides Chronic, Lymphocytic Thyroiditis Chronic, Thyroiditides Chronic Lymphocytic
Documents 27
Hot Single Events 16
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hashimoto Disease. They are ordered first by their relevance to Hashimoto Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT286228 Binding of Tpo and Ceat1 1 0.00 1.28 0.04 100.00
2 INT283520 Binding of DLAT and Pain1 1 0.27 0.65 0.22 5.00
3 INT283460 Binding of CTLA4 and DLAT 1 0.06 3.14 0.09 5.00
4 INT283521 PREB Regulation of Fam89b 1 0.00 1.08 0.07 5.00
5 INT283464 Binding of CD4 and DLAT 1 0.07 0.69 0.04 5.00
6 INT283463 Binding of DLAT and GAGE4 1 0.00 1.1 0.03 5.00
7 INT283462 Binding of DLAT and HLA-DRB1 1 0.07 1.06 0.03 5.00
8 INT286229 Psmb9 Regulation of Tpo 1 0.07 1.01 0 5.00
9 INT283461 Binding of IL2 and SLC4A2 1 0.01 0.98 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hashimoto Disease. They are ordered first by their pain relevance and then by number of times they were reported in Hashimoto Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT286206 Gene_expression of Ceat1 1 0.04 1.48 0.18 100.00
2 INT286193 Negative_regulation of Binding of Ceat1 1 0.03 1.79 0.07 100.00
3 INT286202 Binding of Ceat1 1 0.03 1.78 0.07 100.00
4 INT189088 Gene_expression of Psmb9 2 0.75 18.79 0.75 99.56
5 INT286209 Positive_regulation of Psmb9 1 0.67 5.66 0.54 99.38
6 INT189096 Gene_expression of Psmb8 3 0.47 5.92 0.6 98.96
7 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 94.12
8 INT286191 Negative_regulation of Tpo 1 0.06 1.57 0.05 91.24
9 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 90.88
10 INT286196 Binding of Psmb9 3 0.36 1.95 0.33 90.60
11 INT58769 Binding of MSSE 2 0.31 1.34 0.1 90.40
12 INT45049 Binding of HLA-DRB5 3 0.24 1.4 0.51 89.44
13 INT286208 Negative_regulation of Localization of Psmb9 1 0.41 0.74 0 89.28
14 INT286201 Localization of Psmb9 1 0.73 0.74 0 88.48
15 INT12163 Positive_regulation of OLAH 8 0.68 6.91 1.67 87.68
16 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 84.32
17 INT286199 Regulation of Gene_expression of Psmb9 1 0.44 2.29 0.03 79.64
18 INT286205 Gene_expression of Tpo 1 0.09 2.32 0.18 78.64
19 INT182667 Binding of DLAT 11 0.31 40.75 2.8 68.96
20 INT47949 Positive_regulation of ELOVL1 19 0.42 29.78 3.3 67.04
21 INT202499 Positive_regulation of Psmb8 2 0.42 2.98 0.51 66.72
22 INT286210 Regulation of Psmb9 1 0.44 2.03 0.19 65.72
23 INT36686 Regulation of Tg 7 0.19 3.12 0.45 64.60
24 INT286203 Protein_catabolism of Dag1 2 0.26 1.56 0.22 62.36
25 INT58771 Regulation of Gene_expression of MSSE 1 0.24 0.95 0.08 58.72
26 INT58770 Gene_expression of MSSE 9 0.56 5.75 0.08 58.72
27 INT286194 Positive_regulation of Gene_expression of Tpo 1 0.07 1.16 0.15 56.72
28 INT286204 Positive_regulation of Gene_expression of Psmb8 1 0.30 1.16 0.15 56.12
29 INT286197 Positive_regulation of Gene_expression of Psmb9 1 0.49 2.44 0.21 56.12
30 INT286198 Negative_regulation of Psmb9 1 0.42 2.95 0.03 55.04
31 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 54.32
32 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 54.20
33 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 51.32
34 INT143209 Gene_expression of ALDOC 2 0.18 0.87 0.14 51.32
35 INT227416 Positive_regulation of DLAT 4 0.45 17.02 1.11 44.64
36 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 43.32
37 INT286207 Positive_regulation of Tpo 1 0.07 0.78 0 36.48
38 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 31.76
39 INT184410 Gene_expression of ASF1A 6 0.11 5.51 1.94 29.16
40 INT286200 Gene_expression of Psmb6 1 0.01 0.35 0 22.60
41 INT211969 Positive_regulation of Best1 34 0.11 14.92 1.44 13.04
42 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 12.16
43 INT283459 Localization of Nup210 1 0.73 0.73 0.08 10.64
44 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
45 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 5.00
46 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
47 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
48 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
49 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
50 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 5.00
51 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 5.00
52 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
53 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
54 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
55 INT756 Gene_expression of C3 138 0.75 100.6 19.2 5.00
56 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
57 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
58 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
59 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 5.00
60 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 5.00
61 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 5.00
62 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83 5.00
63 INT169015 Gene_expression of FOXP3 50 0.60 33.18 8.4 5.00
64 INT132278 Binding of CTLA4 32 0.39 18.69 8.17 5.00
65 INT177759 Negative_regulation of IFN1@ 51 0.57 31.81 7.76 5.00
66 INT121496 Gene_expression of TERT 107 0.78 45.6 7.42 5.00
67 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 5.00
68 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 5.00
69 INT23246 Gene_expression of HLA-DRB4 37 0.64 36.79 6.61 5.00
70 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6 5.00
71 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 5.00
72 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 5.00
73 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 5.00
74 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
75 INT84409 Binding of TNS1 6 0.48 2.96 3.33 5.00
76 INT111263 Gene_expression of Gnb5 8 0.75 8.51 3 5.00
77 INT120529 Positive_regulation of ABCC2 7 0.49 2.32 2.94 5.00
78 INT104182 Gene_expression of ABCC2 19 0.76 5.92 2.88 5.00
79 INT95105 Gene_expression of TGFBR2 15 0.64 16.36 2.74 5.00
80 INT3823 Positive_regulation of ALPI 27 0.69 19.49 2.15 5.00
81 INT283506 Gene_expression of SLC4A2 7 0.47 4 1.4 5.00
82 INT12370 Gene_expression of TNS1 6 0.67 1.7 1.37 5.00
83 INT227413 Gene_expression of DLAT 12 0.44 13.21 1.36 5.00
84 INT209961 Binding of GAGE4 3 0.03 1.8 1.16 5.00
85 INT182666 Negative_regulation of DLAT 2 0.38 9.01 1.16 5.00
86 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08 5.00
87 INT22804 Positive_regulation of ALDOC 8 0.41 8.07 1.02 5.00
88 INT264171 Positive_regulation of Positive_regulation of CD4 5 0.49 4.74 0.94 5.00
89 INT283494 Positive_regulation of ABCB11 1 0.13 0.81 0.87 5.00
90 INT283514 Localization of NR1I2 2 0.74 3.15 0.87 5.00
91 INT137082 Regulation of ABCC2 2 0.16 1.11 0.85 5.00
92 INT130582 Gene_expression of ABCB4 3 0.67 1.05 0.82 5.00
93 INT145986 Positive_regulation of CTLA4 8 0.56 2.66 0.82 5.00
94 INT180534 Gene_expression of SARS 40 0.59 35.47 0.81 5.00
95 INT186804 Binding of TLR3 14 0.45 8.41 0.79 5.00
96 INT11657 Gene_expression of ALPI 11 0.71 5.13 0.74 5.00
97 INT283501 Positive_regulation of Gene_expression of SLC4A2 1 0.19 1.66 0.73 5.00
98 INT283516 Localization of SLC4A2 1 0.21 0.8 0.69 5.00
99 INT211972 Regulation of Best1 18 0.33 12.04 0.67 5.00
100 INT154706 Gene_expression of Tg 9 0.38 4.95 0.64 5.00
101 INT283502 Positive_regulation of Gene_expression of ABCB4 1 0.40 0.76 0.62 5.00
102 INT283515 Regulation of ABCB11 2 0.09 0.9 0.58 5.00
103 INT283507 Negative_regulation of Gene_expression of DLAT 1 0.28 2.2 0.48 5.00
104 INT283518 Negative_regulation of Gene_expression of SLC4A2 1 0.16 0.87 0.48 5.00
105 INT283500 Positive_regulation of Gene_expression of ABCB11 1 0.08 0.41 0.48 5.00
106 INT283495 Gene_expression of ABCB11 1 0.10 0.41 0.47 5.00
107 INT283496 Localization of CASR 2 0.76 2.04 0.41 5.00
108 INT96186 Gene_expression of MLF1IP 5 0.53 8.54 0.41 5.00
109 INT211968 Localization of Best1 11 0.40 9.33 0.38 5.00
110 INT237093 Binding of crf 5 0.38 16.18 0.38 5.00
111 INT211971 Binding of Best1 16 0.22 7.73 0.33 5.00
112 INT283504 Negative_regulation of Localization of SLC4A2 1 0.11 0.41 0.32 5.00
113 INT227415 Regulation of DLAT 2 0.29 2.93 0.28 5.00
114 INT227414 Localization of DLAT 2 0.49 5.14 0.26 5.00
115 INT205796 Transcription of ERVW-1 5 0.52 2.16 0.24 5.00
116 INT283509 Regulation of Binding of DLAT 1 0.29 1.99 0.23 5.00
117 INT283503 Binding of SLC4A2 3 0.09 3.39 0.19 5.00
118 INT283508 Negative_regulation of Negative_regulation of DLAT 1 0.28 1.87 0.19 5.00
119 INT285702 Negative_regulation of Tpmt 2 0.28 1.4 0.19 5.00
120 INT283513 Localization of PDHX 1 0.15 2.06 0.18 5.00
121 INT283498 Negative_regulation of Localization of DLAT 1 0.28 1.77 0.14 5.00
122 INT217952 Negative_regulation of MYH7 2 0.01 1.85 0.09 5.00
123 INT256822 Binding of Gm3813 2 0.36 1.81 0.08 5.00
124 INT264170 Binding of BIRC2 1 0.01 1.19 0.08 5.00
125 INT211806 Gene_expression of PLXNC1 4 0.63 2.95 0.07 5.00
126 INT89933 Negative_regulation of Tg 2 0.04 1.78 0.06 5.00
127 INT283499 Negative_regulation of Positive_regulation of CTLA4 1 0.09 1.02 0.05 5.00
128 INT286211 Positive_regulation of Binding of Psmb9 1 0.49 0 0.04 5.00
129 INT283512 Positive_regulation of Binding of CTLA4 1 0.11 1.03 0.03 5.00
130 INT286190 Regulation of Localization of Psmb8 1 0.27 1.03 0 5.00
131 INT286192 Localization of Psmb8 1 0.45 1.02 0 5.00
132 INT286195 Regulation of Tpo 1 0.08 0.34 0 5.00
133 INT283510 Positive_regulation of Localization of DLAT 1 0.33 1.21 0 5.00
134 INT283497 Negative_regulation of SLC4A2 1 0.14 0.95 0 5.00
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