D:Head & Neck Cancer

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Disease Term
Synonyms CANCER OF HEAD, Cancer Of Head Neck, Cancer Of Neck, CANCER OF THE HEAD, Cancer Of The Head Neck, Cancer Of The Neck, Head Cancer, Head Neck Cancer, Head Neck Cancers, HEAD NECK CARCINOMA, HEAD NECK CARCINOMAS
Documents 748
Hot Single Events 132
Hot Interactions 7

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Head & Neck Cancer. They are ordered first by their relevance to Head & Neck Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT290675 SPP1 Positive_regulation of Gene_expression of VEGFA 1 0.16 2.37 0 100.00
2 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35 98.96
3 INT277664 Negative_regulation of Binding of EGF and EGFR 1 0.18 0.5 0 96.52
4 INT145152 Binding of EGF and EGFR 4 0.15 2.45 0.19 96.08
5 INT32211 POMC Positive_regulation of Gene_expression of Lif 1 0.01 0.61 0.15 93.16
6 INT302883 Binding of TXN and Alb 1 0.06 4.13 0.1 90.24
7 INT320700 Ptger2 Positive_regulation of Gene_expression of VEGFC 1 0.00 0.59 0.1 84.84
8 INT320699 Gene_expression of Ptger2 Negative_regulation of Gene_expression of IL2 1 0.00 1.1 0.35 77.56
9 INT122480 Binding of SERPINE1 and PLAU 4 0.40 2.75 0.06 75.00
10 INT147593 Binding of CDK4 and CDKN2A 1 0.42 0.23 0.26 75.00
11 INT147592 Positive_regulation of Binding of CDK4 and CDKN2A 1 0.44 0.23 0.26 75.00
12 INT217139 Binding of MIR103A2 and MIR107 1 0.06 0.83 0 69.96
13 INT330384 IER3 Regulation of USH2A 1 0.00 0.87 0 67.52
14 INT217144 MIR21 Negative_regulation of TPM1 1 0.06 1.03 0 59.12
15 INT327404 Binding of Xiap and Siva1 1 0.02 1.97 0.03 52.88
16 INT217136 Negative_regulation of MIR221 Negative_regulation of Gene_expression of KIT 1 0.18 0.74 0 50.56
17 INT217138 Negative_regulation of MIR222 Negative_regulation of Gene_expression of KIT 1 0.16 0.74 0 50.56
18 INT327167 RETNLB Regulation of IL6 1 0.00 2.26 0.6 50.00
19 INT327164 RETNLB Regulation of TNF 1 0.00 2.27 0.6 50.00
20 INT327165 RETNLB Regulation of Gene_expression of CRP 1 0.01 2.25 0.59 50.00
21 INT327166 RETNLB Regulation of IL36RN 1 0.00 2.25 0.59 50.00
22 INT179683 Binding of Col7a1 and Eln 2 0.00 3.02 0.19 50.00
23 INT327406 Lox Positive_regulation of Lox Positive_regulation of Ptk2 1 0.23 2.62 0.19 50.00
24 INT327405 Lox Positive_regulation of Ptk2 1 0.42 1.3 0.1 50.00
25 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08 50.00
26 INT309904 Binding of ERBB2 and TXK 1 0.01 0.23 0.08 50.00
27 INT309903 Binding of EGF and TXK 1 0.03 0.23 0.08 50.00
28 INT278454 CSF2 Regulation of Hand2 1 0.02 0.66 0.05 50.00
29 INT327403 Bcl2 Positive_regulation of Localization of Mmp2 1 0.19 0.93 0 50.00
30 INT278446 Binding of EGFR and EMR1 1 0.00 0.75 0 50.00
31 INT309906 Binding of EGF and SRC 1 0.11 0.64 0 50.00
32 INT186603 Binding of ERBB2 and Ednra 1 0.02 0.53 0 47.28
33 INT115609 Binding of ERBB2 and SFRP5 3 0.15 1.83 0 47.28
34 INT304279 ETS1 Positive_regulation of MMP2 1 0.05 1.83 0.17 36.20
35 INT304282 ETS1 Positive_regulation of Gene_expression of MMP2 1 0.05 1.83 0.17 36.20
36 INT217148 MIR21 Regulation of BCL2 1 0.32 0.98 0.03 34.72
37 INT267258 Binding of TP53 and BCL11B 1 0.09 0.42 0 34.72
38 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0 24.64
39 INT284231 Binding of TP53 and C4orf3 1 0.02 0.88 0 24.64
40 INT290678 Binding of CHI3L1 and KRTAP19-9P 1 0.08 1.2 0 14.56
41 INT290679 Binding of SPP1 and KRTAP19-9P 1 0.05 1.2 0 14.56
42 INT290676 Binding of CEACAM3 and MUC16 1 0.10 0.7 0.05 13.64
43 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81 6.00
44 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
45 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
46 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
47 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88 5.00
48 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 5.00
49 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83 5.00
50 INT113552 Binding of PLAU and PLAUR 4 0.31 3.09 0.72 5.00
51 INT282286 Akt1 Positive_regulation of Pak1 1 0.15 0.24 0.61 5.00
52 INT190702 CD40 Positive_regulation of Gene_expression of F3 1 0.00 1.4 0.55 5.00
53 INT282284 Cpox Positive_regulation of Akt1 1 0.02 0.47 0.54 5.00
54 INT282282 Ptger2 Positive_regulation of Akt1 1 0.03 0.47 0.54 5.00
55 INT192160 Cxcl9 Negative_regulation of Furin 1 0.02 0.8 0.54 5.00
56 INT192162 Furin Positive_regulation of Mmp14 1 0.10 0.79 0.53 5.00
57 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52 5.00
58 INT282285 Cpox Regulation of Gene_expression of Ptger2 1 0.00 0.84 0.5 5.00
59 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
60 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44 5.00
61 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
62 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
63 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
64 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
65 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
66 INT304277 CCNE1 Positive_regulation of IL1RN 1 0.00 1.93 0.31 5.00
67 INT304278 CCNE1 Positive_regulation of IL8 1 0.02 1.93 0.31 5.00
68 INT304280 CCNE1 Positive_regulation of IL6 1 0.00 1.93 0.31 5.00
69 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
70 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
71 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
72 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 5.00
73 INT354926 IL6 Regulation of Gene_expression of ALB 1 0.14 1.3 0.23 5.00
74 INT354924 IL6 Positive_regulation of Gene_expression of ALB 1 0.26 1.3 0.23 5.00
75 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 5.00
76 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22 5.00
77 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21 5.00
78 INT352961 Ghrl Positive_regulation of Localization of GHSR 1 0.18 1.19 0.21 5.00
79 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2 5.00
80 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2 5.00
81 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
82 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 5.00
83 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
84 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16 5.00
85 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
86 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14 5.00
87 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14 5.00
88 INT188249 PLAT Positive_regulation of PLG 2 0.10 0.86 0.14 5.00
89 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
90 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13 5.00
91 INT330369 Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
92 INT199595 FGF7 Positive_regulation of Transcription of TNF 1 0.40 0.58 0.11 5.00
93 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11 5.00
94 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
95 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
96 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1 5.00
97 INT199594 FGF7 Positive_regulation of NFE2L2 1 0.01 0.52 0.09 5.00
98 INT354925 ALB Positive_regulation of ALPP 1 0.34 1.69 0.09 5.00
99 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09 5.00
100 INT302167 PTGER2 Positive_regulation of EGFR 1 0.10 3.08 0.09 5.00
101 INT199604 Binding of FGF7 and Fgf1 1 0.03 0.21 0.08 5.00
102 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
103 INT199603 Positive_regulation of Binding of FGF7 and Fgf1 1 0.04 0.21 0.08 5.00
104 INT271284 Binding of IFNA1 and Stat1 1 0.07 0.7 0.08 5.00
105 INT251777 Negative_regulation of TXK Positive_regulation of PDGFA 1 0.04 1 0.08 5.00
106 INT302158 CDKN1A Regulation of CDKN2A 1 0.04 0.26 0.08 5.00
107 INT251773 TXK Positive_regulation of PDGFA 1 0.04 1 0.08 5.00
108 INT302139 LAMTOR1 Regulation of CDKN2A 1 0.08 0.26 0.08 5.00
109 INT302157 MRPL28 Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
110 INT302148 IFI27 Regulation of CDKN2A 1 0.11 0.26 0.08 5.00
111 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07 5.00
112 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 5.00
113 INT302131 Negative_regulation of SOD2 Regulation of BAK1 1 0.09 1.22 0.07 5.00
114 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07 5.00
115 INT251775 AGK Negative_regulation of INSRR 1 0.00 1.1 0.07 5.00
116 INT302152 PTGER2 Positive_regulation of EMR1 1 0.01 2.02 0.07 5.00
117 INT302128 SOD2 Regulation of BAK1 1 0.09 1.22 0.07 5.00
118 INT49112 Binding of SERPINB2 and PLAU 2 0.00 2.06 0.06 5.00
119 INT302160 LAMTOR1 Regulation of CDKN1A 1 0.08 0.26 0.06 5.00
120 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06 5.00
121 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06 5.00
122 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06 5.00
123 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06 5.00
124 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06 5.00
125 INT251776 Negative_regulation of TXK Negative_regulation of ERBB4 1 0.04 1.07 0.06 5.00
126 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06 5.00
127 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06 5.00
128 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06 5.00
129 INT302127 MRPL28 Regulation of CDKN1A 1 0.09 0.26 0.06 5.00
130 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06 5.00
131 INT302164 PTEN Regulation of PIK3CD 1 0.16 1.13 0.06 5.00
132 INT251774 Negative_regulation of TXK Negative_regulation of EGFR 1 0.07 1.06 0.06 5.00
133 INT251778 Negative_regulation of TXK Positive_regulation of KDR 1 0.03 0.99 0.05 5.00
134 INT302165 PTGER2 Positive_regulation of Localization of EGFR 1 0.06 1.73 0.05 5.00
135 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05 5.00
136 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05 5.00
137 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05 5.00
138 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05 5.00
139 INT302140 PTGER2 Positive_regulation of VEGFA 1 0.11 1.87 0.05 5.00
140 INT302163 IFI27 Regulation of CDKN1A 1 0.11 0.26 0.05 5.00
141 INT251779 TXK Positive_regulation of KDR 1 0.03 0.99 0.05 5.00
142 INT302166 Positive_regulation of PTGER2 Positive_regulation of EGFR 1 0.07 1.49 0.04 5.00
143 INT330372 Ifx Positive_regulation of IFNA1 1 0.54 0.67 0.04 5.00
144 INT302291 Positive_regulation of EGFR Positive_regulation of Myc 1 0.18 1.3 0.04 5.00
145 INT302162 CASP8 Positive_regulation of CASP3 2 0.01 2.07 0.04 5.00
146 INT302159 TSC1 Positive_regulation of Transcription of CDKN1A 1 0.00 0.28 0.03 5.00
147 INT302153 PTGER2 Positive_regulation of Localization of AREG 1 0.06 1.1 0.03 5.00
148 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03 5.00
149 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03 5.00
150 INT302171 PTGER4 Positive_regulation of RASGRP1 1 0.01 1.03 0.03 5.00
151 INT337622 SERPINB2 Positive_regulation of Binding of F13A1 and PLAU 1 0.01 0.51 0 5.00
152 INT144030 STAT3 Regulation of CCND1 2 0.09 1.05 0 5.00
153 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0 5.00
154 INT217145 Gene_expression of MIR26B Negative_regulation of Gene_expression of MCL1 1 0.10 1 0 5.00
155 INT337614 F13A1 Positive_regulation of Binding of SERPINB2 and PLAU 1 0.01 0.51 0 5.00
156 INT251780 RRAD Negative_regulation of MTOR 1 0.00 0.62 0 5.00
157 INT217143 MIR29A Regulation of Gene_expression of MCL1 1 0.24 1 0 5.00
158 INT274060 EGF Positive_regulation of EGFR Positive_regulation of TKT 1 0.08 1 0 5.00
159 INT337617 F13A1 Positive_regulation of Binding of PLAU and PLAUR 1 0.01 0.51 0 5.00
160 INT306114 GOPC Regulation of Gene_expression of FGF7 1 0.05 0.45 0 5.00
161 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 5.00
162 INT302145 Positive_regulation of AKT1 Positive_regulation of Phosphorylation of BAD 1 0.07 0.9 0 5.00
163 INT302179 PTGER2 Positive_regulation of Phosphorylation of IFI27 1 0.05 0.75 0 5.00
164 INT337616 SERPINE1 Positive_regulation of Binding of PLAU and PLAUR 1 0.03 0.51 0 5.00
165 INT273482 Binding of CYSLTR1 and USE1 1 0.00 0.77 0 5.00
166 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0 5.00
167 INT241852 Binding of EPO and EPCAM 1 0.06 0.84 0 5.00
168 INT267261 GOPC Regulation of BMI1 1 0.06 0.75 0 5.00
169 INT327101 Binding of AREG and EGF 1 0.05 0.35 0 5.00
170 INT292454 Binding of BAD and BCL2 2 0.03 1.73 0 5.00
171 INT282288 Binding of Hmgcr and Nos2 1 0.03 1.99 0 5.00
172 INT186589 Binding of ERBB2 and SCFV 1 0.13 0.65 0 5.00
173 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0 5.00
174 INT302137 Binding of BAD and BAK1 1 0.07 0.93 0 5.00
175 INT337630 Binding of PLAT and PLG 1 0.07 0.69 0 5.00
176 INT337621 F13A1 Positive_regulation of Binding of F13A1 and PLAU 1 0.00 0.51 0 5.00
177 INT337615 SERPINB2 Positive_regulation of Binding of SERPINB2 and PLAU 1 0.02 0.51 0 5.00
178 INT337624 SERPINE1 Positive_regulation of Binding of F13A1 and PLAU 1 0.01 0.51 0 5.00
179 INT267257 BCL11B Regulation of Transcription of BMI1 1 0.28 0.74 0 5.00
180 INT337627 Binding of CLEC3B and Positive_regulation of Positive_regulation of PLG 1 0.52 1.22 0 5.00
181 INT337620 SERPINB2 Positive_regulation of Binding of SERPINE1 and PLAU 1 0.02 0.51 0 5.00
182 INT337628 Binding of HGF and PLG 1 0.17 0.69 0 5.00
183 INT271280 Stat1 Regulation of Mcl1 1 0.28 0.67 0 5.00
184 INT285772 ERCC1 Positive_regulation of Binding of RAD51 1 0.05 0 0 5.00
185 INT302174 Positive_regulation of SRC Positive_regulation of Phosphorylation of STAT3 1 0.11 1.01 0 5.00
186 INT302142 PTGER3 Positive_regulation of SRC 1 0.09 1.07 0 5.00
187 INT345506 Binding of EGFR and FNDC3A 1 0.00 0.08 0 5.00
188 INT185856 Binding of BAD and BCL2L1 4 0.39 2.73 0 5.00
189 INT337633 Binding of F13A1 and PLAU 1 0.01 0.51 0 5.00
190 INT337623 SERPINE1 Positive_regulation of Binding of SERPINE1 and PLAU 1 0.02 0.51 0 5.00
191 INT217150 MIR16-2 Regulation of BCL2 2 0.09 1.89 0 5.00
192 INT271281 Gene_expression of Stat1 Positive_regulation of Insr 1 0.19 0.51 0 5.00
193 INT185353 Eri1 Negative_regulation of Transcription of Egfr 1 0.01 0.5 0 5.00
194 INT217149 MIR20A Regulation of Gene_expression of E2F1 1 0.19 0.86 0 5.00
195 INT302154 STAT3 Regulation of Transcription of CCND1 1 0.04 0.99 0 5.00
196 INT271287 Gene_expression of IFNA1 Positive_regulation of Insr 1 0.03 0.51 0 5.00
197 INT337619 F13A1 Positive_regulation of Binding of SERPINE1 and PLAU 1 0.01 0.51 0 5.00
198 INT273480 Binding of EPO and RNASEL 1 0.08 0.77 0 5.00
199 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0 5.00
200 INT217137 MIR15B Regulation of BCL2 2 0.15 1.88 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Head & Neck Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Head & Neck Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT57439 Regulation of MMP8 6 0.62 2.2 3.54 100.00
2 INT344841 Localization of SSRP1 1 0.04 0.9 0.07 99.52
3 INT343602 Positive_regulation of Tlm 1 0.09 1.74 0 99.48
4 INT343601 Positive_regulation of Positive_regulation of Tlm 1 0.09 0.87 0 99.48
5 INT35029 Positive_regulation of Gene_expression of Ptger2 66 0.43 26.37 13.99 99.36
6 INT3950 Gene_expression of Ptger2 293 0.77 122.28 62.42 99.36
7 INT78060 Positive_regulation of Positive_regulation of Ptger2 11 0.27 5.09 1.14 99.36
8 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 99.32
9 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.28
10 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 99.28
11 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 99.24
12 INT138915 Gene_expression of Stat1 144 0.77 69.53 5.85 99.16
13 INT138917 Positive_regulation of Gene_expression of Stat1 63 0.69 36.76 1.71 99.16
14 INT74019 Regulation of TSC1 27 0.35 23.61 0.79 99.16
15 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 99.16
16 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 99.10
17 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 99.08
18 INT1726 Positive_regulation of Kitl 65 0.70 38.81 44.85 99.08
19 INT11154 Binding of EGFR 149 0.48 96.23 6.29 99.04
20 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.04
21 INT32207 Regulation of Gene_expression of Lif 3 0.19 1.01 0.42 98.96
22 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66 98.96
23 INT738 Regulation of POMC 459 0.62 111.19 243.74 98.96
24 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 98.92
25 INT18522 Positive_regulation of Gene_expression of IFNA1 248 0.67 160.85 44.87 98.92
26 INT32208 Gene_expression of Lif 23 0.74 6.23 3.7 98.88
27 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 98.64
28 INT82611 Negative_regulation of SRC 30 0.57 20.16 5.47 98.64
29 INT110988 Gene_expression of Insr 58 0.42 42.12 12.18 98.64
30 INT124736 Positive_regulation of Gene_expression of Insr 6 0.31 7.55 3.12 98.64
31 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79 98.56
32 INT192958 Negative_regulation of IGF1R 8 0.30 6.35 0.21 98.44
33 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 98.16
34 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 97.96
35 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 97.88
36 INT11893 Positive_regulation of Ptger2 96 0.69 31.49 21.92 97.84
37 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 97.68
38 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 97.64
39 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 97.52
40 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7 97.52
41 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 97.34
42 INT22383 Binding of IL2 59 0.48 39.06 8.56 97.32
43 INT117392 Binding of Insr 8 0.23 4.88 0.68 97.08
44 INT29555 Positive_regulation of CALM1 58 0.69 14.09 17.37 97.02
45 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 96.88
46 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 96.88
47 INT45503 Binding of EPO 42 0.48 24.85 2.88 96.68
48 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 96.56
49 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 96.56
50 INT223597 Negative_regulation of Binding of EGFR 12 0.43 7.97 0.23 96.52
51 INT70652 Negative_regulation of Binding of EGF 7 0.43 4.23 0.7 96.52
52 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 96.44
53 INT32557 Negative_regulation of Negative_regulation of PTGS1 8 0.43 3.44 2.1 96.44
54 INT14823 Gene_expression of MET 103 0.75 51.92 32.48 96.36
55 INT176533 Positive_regulation of Gene_expression of MET 13 0.67 7.17 0.06 96.36
56 INT214706 Gene_expression of Bok 3 0.09 7.22 0.11 96.32
57 INT118292 Negative_regulation of Phosphorylation of EGFR 27 0.59 13.62 1.54 96.24
58 INT96994 Phosphorylation of EGFR 99 0.82 52.75 7.33 96.24
59 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45 96.20
60 INT174192 Negative_regulation of Gene_expression of CXADR 6 0.41 2.79 0 96.20
61 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 96.12
62 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 96.12
63 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68 96.12
64 INT11157 Binding of EGF 88 0.48 53.73 21.25 96.08
65 INT119203 Gene_expression of CXADR 64 0.74 11.37 4.41 95.80
66 INT83374 Gene_expression of FGF7 83 0.78 44.18 2.6 95.72
67 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 95.64
68 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 95.64
69 INT36405 Positive_regulation of Insr 26 0.66 24.5 7.24 95.64
70 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46 95.20
71 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 95.20
72 INT7696 Negative_regulation of Fdft1 9 0.21 2.8 5.64 95.12
73 INT67039 Positive_regulation of Cpox 144 0.65 98.4 33.77 94.08
74 INT277666 Negative_regulation of Positive_regulation of TKT 1 0.08 0.5 0 93.92
75 INT78320 Gene_expression of EPCAM 57 0.75 50.34 7.53 93.60
76 INT256048 Negative_regulation of Gene_expression of EPCAM 7 0.41 4.37 0.57 93.60
77 INT51262 Positive_regulation of TKT 7 0.69 4.31 0.82 93.32
78 INT82744 Regulation of Gene_expression of Myh13 2 0.59 2.09 0.47 93.32
79 INT117348 Regulation of EGFR 75 0.61 47.73 3.09 93.20
80 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 93.20
81 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 93.00
82 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 92.96
83 INT139976 Regulation of Tp53 7 0.44 6.49 0.39 92.88
84 INT45142 Gene_expression of DCPS 109 0.56 84.71 16.87 92.48
85 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 91.92
86 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 91.80
87 INT69993 Positive_regulation of Gene_expression of Cpox 93 0.55 69.4 22.05 91.80
88 INT192806 Binding of SSRP1 11 0.27 9.12 0.37 91.72
89 INT82745 Gene_expression of Myh13 7 0.78 8.16 2.28 91.36
90 INT88935 Positive_regulation of SPP1 36 0.70 31.07 5.49 90.76
91 INT285811 Localization of RAD1 2 0.73 0.09 0 90.72
92 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 90.36
93 INT90094 Gene_expression of Cytl1 14 0.75 12.75 2.81 90.36
94 INT192807 Gene_expression of SSRP1 14 0.49 19.28 1.15 89.92
95 INT234 Binding of Alb 151 0.48 52.34 32.97 89.36
96 INT172525 Localization of PSEN2 5 0.73 4.17 0.24 89.24
97 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 88.84
98 INT225138 Positive_regulation of ENOPH1 4 0.15 2 0.28 88.28
99 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 88.08
100 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 87.60
101 INT94756 Positive_regulation of PSEN2 8 0.49 4.59 0.77 87.52
102 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19 86.64
103 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 86.60
104 INT118791 Binding of AKT1 32 0.48 15.51 2.25 86.20
105 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 85.60
106 INT213923 Positive_regulation of MTOR 16 0.65 9.28 0.7 85.36
107 INT25022 Binding of PAEP 66 0.42 22.83 6.59 84.92
108 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 84.56
109 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47 84.40
110 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13 84.40
111 INT184530 Regulation of SMUG1 4 0.52 3.54 0.16 83.68
112 INT76752 Negative_regulation of TOP2B 8 0.42 6.2 0.14 83.04
113 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17 82.68
114 INT14048 Negative_regulation of TKT 13 0.34 5.05 1.51 82.64
115 INT284237 Regulation of Gene_expression of LILRA3 1 0.07 0.61 0 82.16
116 INT209948 Gene_expression of CLEC3B 3 0.78 11.51 0.6 82.16
117 INT132997 Localization of Mmp9 59 0.80 45.9 17.61 82.08
118 INT111398 Localization of Mmp2 37 0.76 23.78 7.17 82.08
119 INT300514 Positive_regulation of Gene_expression of VEGFC 5 0.67 3.85 0.34 81.56
120 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 81.36
121 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 81.20
122 INT251788 Gene_expression of ESYT1 8 0.06 7.29 0.23 81.20
123 INT97128 Localization of SPP1 32 0.80 21.75 4.02 80.96
124 INT89240 Gene_expression of VEGFC 23 0.75 15.94 2.03 80.96
125 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 80.88
126 INT249699 Gene_expression of KLRC1 7 0.58 7.35 0.53 80.68
127 INT174193 Gene_expression of LILRA3 20 0.28 12.65 5.1 80.56
128 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 80.48
129 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 80.32
130 INT49128 Gene_expression of IGF1R 35 0.63 23.48 1.39 80.24
131 INT97245 Gene_expression of AKT1 217 0.77 119.63 15.59 80.24
132 INT41719 Gene_expression of MTOR 27 0.77 19.43 1.44 80.24
133 INT145312 Localization of CHI3L1 8 0.78 12.71 1.26 79.52
134 INT217162 Negative_regulation of MIR21 7 0.30 7.01 0.34 79.20
135 INT191678 Gene_expression of Xiap 60 0.71 57.25 1.37 79.04
136 INT203260 Negative_regulation of Gene_expression of Xiap 4 0.54 4.54 0.1 79.04
137 INT87699 Positive_regulation of WAS 16 0.45 5.84 8.03 78.92
138 INT159634 Negative_regulation of Positive_regulation of DCPS 2 0.13 2.39 0.58 78.00
139 INT322696 Localization of Sftpd 1 0.09 0.62 0.05 78.00
140 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 77.92
141 INT174553 Localization of Stat1 17 0.80 6.62 0.73 77.72
142 INT11894 Negative_regulation of Gene_expression of Ptger2 47 0.55 16.95 11.59 77.56
143 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 77.40
144 INT71807 Negative_regulation of Cp 18 0.58 8.9 1.88 76.88
145 INT159631 Positive_regulation of DCPS 60 0.27 43.23 10.3 76.84
146 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 76.40
147 INT116540 Binding of Twist1 35 0.48 16.32 2.85 75.96
148 INT22764 Localization of Ptger2 81 0.64 24.38 26.77 75.84
149 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 75.44
150 INT181809 Gene_expression of Atxn1 81 0.77 28.66 1.42 75.44
151 INT132384 Gene_expression of Msi1 2 0.20 1.27 0.33 75.44
152 INT95133 Gene_expression of FASLG 38 0.75 44.09 7.51 75.36
153 INT82747 Negative_regulation of Gene_expression of Myh13 2 0.59 2.38 0.7 75.24
154 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 75.20
155 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 75.00
156 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71 75.00
157 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 75.00
158 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 75.00
159 INT78472 Gene_expression of CDKN2A 223 0.78 173.76 13.61 75.00
160 INT125467 Positive_regulation of Gene_expression of CDKN2A 35 0.63 39.07 5.56 75.00
161 INT91401 Binding of OGFR 12 0.41 4.1 4.47 75.00
162 INT154233 Negative_regulation of Lox 32 0.56 38.89 3.17 75.00
163 INT172872 Positive_regulation of Lox 12 0.49 12.99 1.29 75.00
164 INT147598 Negative_regulation of Positive_regulation of CDKN2A 3 0.41 1.47 0.59 75.00
165 INT91432 Binding of MMRN1 23 0.36 9.79 2.95 75.00
166 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36 75.00
167 INT122481 Binding of PLAU 10 0.36 6.1 1.16 75.00
168 INT206471 Positive_regulation of Ptk2 34 0.51 25.75 1.61 75.00
169 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 75.00
170 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 75.00
171 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 75.00
172 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42 75.00
173 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96 75.00
174 INT116114 Phosphorylation of EID1 8 0.12 3.99 1.75 75.00
175 INT78470 Negative_regulation of Gene_expression of CDKN2A 14 0.59 14.44 1.38 75.00
176 INT147602 Negative_regulation of CDK4 8 0.35 4.6 1.04 75.00
177 INT301115 Negative_regulation of Positive_regulation of Mmp2 3 0.38 3.04 0.06 75.00
178 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 74.84
179 INT217186 Gene_expression of MIR155 26 0.48 29.45 7.92 74.52
180 INT217208 Positive_regulation of Gene_expression of MIR155 3 0.31 2.7 0.29 74.52
181 INT197765 Gene_expression of Sln 26 0.58 12.11 0.45 73.76
182 INT267269 Gene_expression of BCL11B 62 0.78 48.75 0.55 73.28
183 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81 72.32
184 INT138922 Positive_regulation of Stat1 57 0.69 28.35 7.2 71.88
185 INT241862 Negative_regulation of Gene_expression of EPOR 1 0.31 1.13 0 71.68
186 INT1923 Regulation of CEACAM7 9 0.41 7.36 0.31 71.56
187 INT241857 Gene_expression of EPOR 14 0.77 5.21 0.13 71.36
188 INT12922 Gene_expression of Atp9a 115 0.75 50.95 17.01 70.68
189 INT217154 Gene_expression of MIR103A2 2 0.18 1.42 0 70.52
190 INT217207 Gene_expression of MIR107 1 0.48 1.37 0 70.52
191 INT78469 Negative_regulation of Man2a1 1 0.42 1.58 0.1 70.48
192 INT267270 Binding of NR2F1 1 0.07 0.72 0 70.36
193 INT22708 Gene_expression of MUC1 297 0.78 232.71 24.19 70.20
194 INT217228 Binding of MIR103A2 1 0.08 0.83 0 69.96
195 INT126714 Binding of Xpc 1 0.34 1.69 0.1 69.64
196 INT217177 Binding of MIR107 1 0.22 0.82 0 69.48
197 INT46877 Negative_regulation of CLEC3B 2 0.43 6.35 0.04 69.32
198 INT217167 Negative_regulation of Gene_expression of MIR155 4 0.23 3.43 0.91 68.36
199 INT66585 Gene_expression of IER3 13 0.63 7.39 3.48 68.16
200 INT8111 Localization of EPO 32 0.81 19.53 2.54 68.08
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