D:Head Trauma

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Disease Term
Synonyms ACUTE SUBDURAL HAEMATOMA, ACUTE SUBDURAL HEMATOMA, CEREBRAL CONTUSION, CEREBRAL CONTUSIONS, Cerebral Laceration, Cerebral Lacerations, Chronic Persistent Vegetative State, CHRONIC SUBDURAL HAEMATOMA, Chronic Subdural Hematoma, CHRONIC VEGETATIVE STATE, CONCUSSION
Documents 1922
Hot Single Events 156
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Head Trauma. They are ordered first by their relevance to Head Trauma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT261648 BDKRB1 Regulation of PRKCA 1 0.03 1.9 0.47 95.88
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36 82.08
3 INT202969 Positive_regulation of SGSM3 Positive_regulation of MCRS1 1 0.02 1.22 0.47 58.48
4 INT202964 SGSM3 Positive_regulation of MCRS1 1 0.03 1.21 0.47 58.48
5 INT109098 Binding of ABL2 and PON1 1 0.36 1.32 0.28 40.80
6 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0 27.76
7 INT262714 ACOT1 Positive_regulation of Negative_regulation of ACHE 1 0.06 1.41 0.08 18.68
8 INT202965 Binding of STC2 and BAG3 1 0.02 7.86 2.96 16.68
9 INT276964 Binding of Tlr1 and Tlr2 11 0.24 4.22 0.89 15.44
10 INT276988 Binding of Tlr6 and Tlr2 11 0.26 4.89 0.79 15.44
11 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18 7.80
12 INT170658 Binding of Ntf3 and Csf2 1 0.33 0.8 0.74 7.80
13 INT170654 Binding of Ntf3 and Ngf 1 0.38 1.66 1.54 6.44
14 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 5.00
15 INT202959 Binding of BAG3 and MCRS1 1 0.11 7.46 3.14 5.00
16 INT202974 Binding of BAG3 and CPP 1 0.25 6.22 2.73 5.00
17 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 5.00
18 INT202963 Binding of STC2 and CPP 1 0.02 5.16 2.04 5.00
19 INT267133 Binding of ICAM1 and VCAM1 25 0.32 25.43 1.83 5.00
20 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65 5.00
21 INT202958 Binding of STC2 and MCRS1 1 0.01 3.48 1.44 5.00
22 INT202960 Binding of MCRS1 and CPP 1 0.14 2.49 1.13 5.00
23 INT202968 Binding of MCRS1 and CAP1 1 0.03 2.46 1.08 5.00
24 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05 5.00
25 INT278224 Binding of ACSM3 and SNRNP70 1 0.04 3.76 1.01 5.00
26 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
27 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73 5.00
28 INT202962 CPP Negative_regulation of Positive_regulation of BAG3 1 0.26 1.34 0.61 5.00
29 INT202971 Binding of BAG3 and CAP1 1 0.04 1.26 0.59 5.00
30 INT202973 Binding of CAP1 and CPP 1 0.05 1.24 0.58 5.00
31 INT202970 Binding of STC2 and CAP1 1 0.00 1.25 0.58 5.00
32 INT202972 Positive_regulation of MCRS1 Negative_regulation of CPP 1 0.16 1.64 0.57 5.00
33 INT202961 MCRS1 Negative_regulation of STC2 1 0.00 1.63 0.57 5.00
34 INT278227 Binding of MBNL1 and SNRNP70 1 0.01 2.05 0.54 5.00
35 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54 5.00
36 INT179503 Cd14 Regulation of Positive_regulation of Tlr4 1 0.38 0.58 0.52 5.00
37 INT202957 CPP Negative_regulation of MCRS1 1 0.14 1.53 0.51 5.00
38 INT179507 Tlr4 Positive_regulation of Tlr2 2 0.17 1.07 0.49 5.00
39 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
40 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
41 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
42 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46 5.00
43 INT170656 Ntf3 Positive_regulation of Csf2 1 0.35 1.46 0.44 5.00
44 INT170657 Ntf3 Regulation of Csf2 1 0.31 0.46 0.43 5.00
45 INT316063 Ps Positive_regulation of IL8 1 0.09 1.33 0.41 5.00
46 INT261652 Binding of MAPK1 and PSEN1 1 0.22 1.25 0.41 5.00
47 INT316065 Eif1 Positive_regulation of IL8 1 0.01 1.34 0.41 5.00
48 INT355018 Binding of FAS and Faslg 1 0.12 1.34 0.37 5.00
49 INT278225 Binding of FOSB and SNRNP70 1 0.00 1.22 0.36 5.00
50 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36 5.00
51 INT230775 CEBPZ Regulation of CPP 1 0.11 0.69 0.27 5.00
52 INT198926 Binding of Apbb1 and Lrp1 5 0.12 2.18 0.24 5.00
53 INT261650 LGR6 Positive_regulation of MAPK1 1 0.04 0.71 0.24 5.00
54 INT274005 KCNK3 Positive_regulation of SYNM 1 0.06 0 0.23 5.00
55 INT295329 ecs Positive_regulation of TF 1 0.00 1.2 0.23 5.00
56 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22 5.00
57 INT188746 Binding of CSF2 and HIVEP1 1 0.04 3.99 0.21 5.00
58 INT316054 Eif1 Positive_regulation of Il6 1 0.00 0.78 0.21 5.00
59 INT316062 Ps Positive_regulation of Il6 1 0.04 0.77 0.21 5.00
60 INT316064 Binding of RBPJ and Csl 1 0.16 0.33 0.2 5.00
61 INT293056 Binding of ANXA5 and GOPC 1 0.06 0.51 0.19 5.00
62 INT261579 Serpinc1 Negative_regulation of Gene_expression of CYBB 1 0.00 1.69 0.18 5.00
63 INT179504 Tlr4 Regulation of Myd88 1 0.07 0.29 0.17 5.00
64 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17 5.00
65 INT179506 Tlr4 Regulation of Cd14 1 0.20 0.29 0.17 5.00
66 INT179501 Tlr4 Regulation of Nfkb1 1 0.05 0.3 0.17 5.00
67 INT264277 Binding of Car2 and P2rx1 1 0.10 0 0.16 5.00
68 INT264276 Binding of Ednrb and P2rx1 1 0.00 0.17 0.16 5.00
69 INT261577 Nos2 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.16 5.00
70 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15 5.00
71 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15 5.00
72 INT208458 TWIST1 Positive_regulation of Localization of Bdnf 1 0.01 0.19 0.15 5.00
73 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15 5.00
74 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15 5.00
75 INT330800 Binding of S100A1 and S100B 1 0.32 0.5 0.13 5.00
76 INT316059 Ps Regulation of Binding of Cd4 1 0.06 0.86 0.13 5.00
77 INT316058 Ps Regulation of Binding of Cd8a 1 0.02 0.86 0.13 5.00
78 INT310412 Binding of CP and TF 1 0.14 1.66 0.13 5.00
79 INT208459 Galns Negative_regulation of Negative_regulation of BCAN 1 0.01 0.44 0.13 5.00
80 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11 5.00
81 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11 5.00
82 INT355023 Phosphorylation of Rtn4r Negative_regulation of Binding of Mag and Rtn4r 1 0.00 0.38 0.11 5.00
83 INT355008 Binding of Mag and Rtn4r 1 0.02 0.36 0.1 5.00
84 INT294637 Bcl2a1a Positive_regulation of Gene_expression of Bcl2 1 0.15 0.97 0.09 5.00
85 INT280451 IER5 Positive_regulation of Phc1 1 0.00 0.56 0.09 5.00
86 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
87 INT355021 Cntf Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
88 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08 5.00
89 INT188748 AGRP Negative_regulation of CSF2 1 0.05 1.26 0.08 5.00
90 INT355009 Cntf Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
91 INT188745 AGRP Regulation of Gene_expression of CSF2 1 0.07 1.48 0.08 5.00
92 INT355020 Lif Positive_regulation of SOAT1 1 0.02 0.7 0.08 5.00
93 INT355010 Lif Positive_regulation of Il6st 1 0.02 0.69 0.08 5.00
94 INT221878 Binding of Ltp and Ctrcts 1 0.00 1.94 0.07 5.00
95 INT294638 Bcl2a1a Positive_regulation of Tlr2 1 0.58 0.43 0.07 5.00
96 INT298733 INS Regulation of ACSBG1 1 0.00 0.97 0.05 5.00
97 INT298734 USE1 Regulation of ACSBG1 1 0.00 0.97 0.05 5.00
98 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 5.00
99 INT215281 Mpz Positive_regulation of Gene_expression of Ros1 2 0.01 1.01 0.05 5.00
100 INT198934 Binding of App and Lrp1b 2 0.27 1.62 0.05 5.00
101 INT319578 CYP3A4 Regulation of ALPPL2 1 0.00 0.56 0.05 5.00
102 INT294639 Bcl2a1a Positive_regulation of Gene_expression of Chkb 1 0.19 1.02 0.04 5.00
103 INT198923 Gene_expression of Lrp8 Positive_regulation of Gene_expression of Lifr 1 0.01 0 0.04 5.00
104 INT198922 Lrp8 Negative_regulation of Binding of Vldlr 1 0.19 0 0.04 5.00
105 INT261647 Positive_regulation of PRKCA Positive_regulation of Phosphorylation of BDKRB1 1 0.04 0.6 0.04 5.00
106 INT261649 Positive_regulation of PRKCA Positive_regulation of BDKRB1 1 0.04 0.59 0.04 5.00
107 INT198917 Lrp8 Negative_regulation of Binding of Reln 1 0.15 0 0.04 5.00
108 INT198930 Binding of Lrp8 and Vldlr 1 0.16 0 0.04 5.00
109 INT199406 Binding of CYP3A4 and PPIB 1 0.40 0 0.04 5.00
110 INT198919 Binding of Lrp1 and Lrpap1 1 0.07 0 0.04 5.00
111 INT198935 Lrp8 Negative_regulation of Binding of Reln and Reln 1 0.07 0 0.04 5.00
112 INT316060 Binding of Erbb4 and Ncor2 1 0.12 0.41 0.03 5.00
113 INT316061 Positive_regulation of Binding of Erbb4 and Nrg1 1 0.03 0.38 0.03 5.00
114 INT198921 Binding of App and Lrp1 3 0.32 2.7 0.03 5.00
115 INT316057 Binding of Erbb4 and Nrg1 2 0.03 0.38 0.03 5.00
116 INT219352 CDK5 Negative_regulation of PAK1 1 0.22 0.72 0.03 5.00
117 INT346331 Binding of Epo and Egf 1 0.19 0.1 0.03 5.00
118 INT316056 Binding of Ncor2 and Tab2 1 0.12 0.41 0.03 5.00
119 INT317310 Binding of Large and Psmb10 1 0.00 0.94 0.03 5.00
120 INT316055 Binding of Erbb4 and Tab2 1 0.23 0.4 0.03 5.00
121 INT264278 Lta Negative_regulation of Skap2 1 0.15 0 0.03 5.00
122 INT317301 Binding of Park2 and Park7 1 0.36 0.62 0 5.00
123 INT317318 Binding of Gfm1 and Trap1 1 0.01 0.83 0 5.00
124 INT317317 Binding of Psmb10 and Gfm1 1 0.00 0.73 0 5.00
125 INT316101 Binding of HIST1H4PS1 and ANGPTL5 1 0.01 0.28 0 5.00
126 INT219353 Binding of SMARCB1 and PPP1R15A 1 0.07 3.03 0 5.00
127 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0 5.00
128 INT317316 Park7 Positive_regulation of Protein_catabolism of Hmbs 1 0.11 0.68 0 5.00
129 INT299232 Onc1 Regulation of Gene_expression of Aqp4 1 0.01 0.43 0 5.00
130 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0 5.00
131 INT293055 Binding of ANXA5 and PRSS1 1 0.00 0.59 0 5.00
132 INT198918 Binding of Gpx3 and Lrp8 1 0.00 0.17 0 5.00
133 INT317302 Binding of Park2 and Mul1 1 0.01 0.62 0 5.00
134 INT317321 Mpz Positive_regulation of Gene_expression of Zfp263 1 0.02 0.58 0 5.00
135 INT317324 Park7 Positive_regulation of Protein_catabolism of SNCAIP 1 0.38 0.69 0 5.00
136 INT198933 Binding of Apoe and App 1 0.33 0.19 0 5.00
137 INT188747 AGRP Positive_regulation of Gene_expression of CSF2 1 0.06 1.28 0 5.00
138 INT317307 Binding of Hsp90aa1 and Pink1 1 0.12 0.56 0 5.00
139 INT299234 Onc1 Negative_regulation of Thy1 1 0.02 0.16 0 5.00
140 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0 5.00
141 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0 5.00
142 INT219348 Binding of SMARCB1 and DDI1 1 0.01 3.02 0 5.00
143 INT211067 Pth Regulation of DMD 1 0.01 0.12 0 5.00
144 INT188744 AGRP Regulation of CSF2 1 0.05 1.04 0 5.00
145 INT198927 Lrp1 Regulation of App 1 0.14 0.42 0 5.00
146 INT219349 FGFR1 Positive_regulation of Gene_expression of MMP11 1 0.09 0.55 0 5.00
147 INT219354 FGFR1 Positive_regulation of Gene_expression of PAK1 1 0.10 0.55 0 5.00
148 INT308030 Binding of Mpz and ASPM 1 0.02 0.55 0 5.00
149 INT219385 FGFR1 Positive_regulation of Sympk 1 0.00 0.53 0 5.00
150 INT198915 Binding of App and Lrp8 1 0.24 0.17 0 5.00
151 INT188749 Binding of HIVEP1 and ADC 1 0.02 0.92 0 5.00
152 INT262716 Binding of ACHE and BCHE 1 0.09 0.11 0 5.00
153 INT317308 Binding of Park7 and Mul1 1 0.01 0.62 0 5.00
154 INT219351 FGFR1 Positive_regulation of Gene_expression of SMARCB1 1 0.10 0.55 0 5.00
155 INT317319 Binding of Trap1 and Pink1 1 0.26 2.67 0 5.00
156 INT198925 Binding of App and Ldlr 1 0.14 0.15 0 5.00
157 INT317306 Binding of Mul1 and Pink1 1 0.01 0.62 0 5.00
158 INT308029 ASPM Positive_regulation of Regulation of Mpz 1 0.02 0.55 0 5.00
159 INT188750 Binding of CD4 and ADC 1 0.16 0.93 0 5.00
160 INT299233 Onc1 Regulation of Gene_expression of Aqp9 1 0.01 0.19 0 5.00
161 INT198928 Binding of Apbb1 and Lrp8 1 0.07 0.17 0 5.00
162 INT317314 Gfm1 Positive_regulation of Gene_expression of Ros1 1 0.00 0.61 0 5.00
163 INT269769 Gh Regulation of Gene_expression of Igf1 1 0.04 0.98 0 5.00
164 INT317311 Binding of Cdc37 and Pink1 1 0.13 0.56 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Head Trauma. They are ordered first by their pain relevance and then by number of times they were reported in Head Trauma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT52052 Positive_regulation of SDHB 14 0.68 14.07 2.27 100.00
2 INT8960 Binding of SDHB 9 0.36 9.2 1.68 100.00
3 INT134346 Binding of PCS 51 0.37 22.27 5.67 100.00
4 INT63074 Gene_expression of FOSB 19 0.53 13.58 4.91 100.00
5 INT52053 Positive_regulation of Positive_regulation of SDHB 2 0.49 3.11 0.14 100.00
6 INT5286 Gene_expression of ANTXR2 46 0.75 21.06 3.41 100.00
7 INT105762 Positive_regulation of Pvr 6 0.40 2.13 0.65 100.00
8 INT10228 Positive_regulation of PCS 49 0.67 28.72 7 100.00
9 INT102470 Negative_regulation of Pvr 3 0.37 2.36 0.32 100.00
10 INT48473 Binding of Smcp 5 0.31 5.14 0.24 100.00
11 INT124191 Localization of SDHB 3 0.74 2.4 0.32 100.00
12 INT124834 Negative_regulation of fh 1 0.00 1.03 0.54 100.00
13 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 99.92
14 INT22938 Gene_expression of Vent1 1 0.00 0.51 0.4 99.92
15 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 99.90
16 INT48144 Gene_expression of Fgf2 117 0.78 43 20.48 99.84
17 INT107653 Gene_expression of ACAT1 9 0.60 4.74 1.03 99.84
18 INT107652 Gene_expression of C7 4 0.60 2.06 0.56 99.84
19 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.80
20 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 99.80
21 INT335032 Binding of THEG 1 0.04 2.4 0.2 99.76
22 INT162253 Gene_expression of BAG3 30 0.59 20.16 7.18 99.60
23 INT54256 Negative_regulation of Transcription of Cyp2c11 4 0.42 1.87 0.21 99.58
24 INT202978 Gene_expression of STC2 11 0.50 13.46 4.06 99.46
25 INT104756 Gene_expression of ACSM3 8 0.58 8.76 1.83 99.44
26 INT122500 Protein_catabolism of Slco1c1 17 0.52 16.7 1.7 99.44
27 INT182145 Regulation of Protein_catabolism of Slco1c1 2 0.18 2.5 0.36 99.44
28 INT53020 Positive_regulation of ACSM3 9 0.58 11.03 2.73 99.40
29 INT16395 Gene_expression of CEBPZ 30 0.57 11.02 6.66 99.36
30 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 99.34
31 INT334798 Regulation of REXO4 1 0.16 0.99 0.32 99.32
32 INT4557 Gene_expression of Otor 4 0.11 5.85 0.41 99.16
33 INT54777 Positive_regulation of Bp28 1 0.01 0.94 0.77 99.16
34 INT54778 Regulation of Positive_regulation of Bp28 1 0.01 0.94 0.77 99.16
35 INT54780 Regulation of Bp28 1 0.01 0.94 0.77 99.16
36 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 99.12
37 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 99.04
38 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86 99.02
39 INT146109 Positive_regulation of Serping1 4 0.59 2.73 0.68 99.02
40 INT54255 Transcription of Cyp2c11 5 0.66 2.01 0.3 99.00
41 INT54254 Transcription of Cyp3a62 3 0.52 1.79 0.17 99.00
42 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 98.96
43 INT18894 Gene_expression of CPP 44 0.77 23.05 23.05 98.96
44 INT10101 Binding of PLAT 24 0.36 12.62 2.78 98.88
45 INT54779 Binding of Bp28 1 0.01 0.93 0.7 98.84
46 INT67855 Negative_regulation of PPIG 64 0.57 17.83 13.54 98.72
47 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 98.52
48 INT65208 Positive_regulation of Positive_regulation of COL1A2 3 0.14 2.63 0.32 98.40
49 INT62669 Positive_regulation of COL1A2 13 0.49 6.89 1.4 98.40
50 INT258979 Protein_catabolism of Otor 1 0.17 2.08 0.12 98.40
51 INT46460 Gene_expression of NAV1 288 0.78 135.51 305.75 98.40
52 INT4555 Positive_regulation of Otor 6 0.31 8.79 1.29 98.08
53 INT111073 Gene_expression of Psen1 167 0.76 78.65 15.83 98.08
54 INT193863 Gene_expression of Ncstn 7 0.29 3.88 0.66 98.08
55 INT237402 Positive_regulation of Gene_expression of Ncstn 3 0.26 2.78 0.48 98.08
56 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 97.96
57 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08 97.96
58 INT169475 Localization of HRAS 14 0.73 9.02 3.9 97.96
59 INT7674 Regulation of ENG 42 0.30 11.41 14.44 97.84
60 INT145774 Positive_regulation of C5 7 0.67 4.88 2.79 97.84
61 INT181507 Positive_regulation of Psen1 22 0.49 7.59 2.04 97.68
62 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37 97.64
63 INT20981 Binding of HRAS 42 0.48 24.49 4.23 97.56
64 INT316044 Positive_regulation of Ncstn 1 0.20 1.37 0.32 97.36
65 INT63121 Binding of APC 29 0.41 23.02 3.8 97.24
66 INT289719 Gene_expression of BPPV 2 0.51 2.96 0.47 96.76
67 INT289720 Positive_regulation of Gene_expression of BPPV 1 0.35 1.63 0.1 96.76
68 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 96.32
69 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 96.12
70 INT197493 Localization of Apoe 61 0.79 27.48 7.06 96.04
71 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43 95.88
72 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 95.74
73 INT258978 Positive_regulation of Gene_expression of Otor 1 0.07 1.13 0 95.60
74 INT258980 Negative_regulation of Gene_expression of Otor 1 0.06 1.24 0 95.28
75 INT85285 Positive_regulation of Gene_expression of ENO2 4 0.50 4.15 0.61 95.24
76 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 95.16
77 INT202983 Regulation of STC2 1 0.03 11.98 3.33 94.88
78 INT59983 Regulation of BDKRB1 12 0.45 10.69 5.11 94.84
79 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 94.72
80 INT27236 Negative_regulation of F13a1 17 0.53 10.79 1.99 94.60
81 INT261686 Phosphorylation of BDKRB1 1 0.13 6.07 0.92 93.88
82 INT93037 Regulation of Grin2b 26 0.57 11.9 16.92 93.80
83 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 93.72
84 INT4065 Binding of cerebral blood flow 4 0.02 1.33 0.72 93.72
85 INT56817 Regulation of Eno2 16 0.61 10.64 1.99 93.64
86 INT221676 Protein_catabolism of Bcl2 4 0.24 2.77 0.48 93.60
87 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 92.80
88 INT81628 Positive_regulation of Gene_expression of Fas 32 0.67 38.13 4.23 92.80
89 INT211830 Binding of PVR 3 0.32 2.26 0.03 92.80
90 INT69419 Binding of BPPV 5 0.32 7.9 0.7 92.56
91 INT53388 Negative_regulation of Cyp2c11 18 0.53 2.66 3.11 92.24
92 INT90766 Gene_expression of PCS 93 0.77 40.48 14.51 92.16
93 INT58565 Localization of Bh4p 2 0.03 0.98 0.12 92.16
94 INT4585 Gene_expression of Serping1 19 0.46 12.4 2.35 92.08
95 INT55476 Negative_regulation of ITGA2 8 0.55 3.55 1.33 92.00
96 INT46797 Negative_regulation of Cyp3a62 27 0.59 7.06 13.97 91.76
97 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 91.72
98 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 91.72
99 INT71780 Phosphorylation of TYR 12 0.34 17.21 1.62 91.64
100 INT14049 Positive_regulation of GRIN1 102 0.70 48.31 71.06 91.56
101 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 91.44
102 INT72141 Binding of Apoe 11 0.37 10.91 3.27 91.28
103 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56 91.00
104 INT61087 Positive_regulation of Gene_expression of Il2ra 12 0.35 9.1 3.25 91.00
105 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 90.64
106 INT10189 Negative_regulation of Gene_expression of Il2ra 8 0.32 8.05 2.91 90.64
107 INT162254 Regulation of BAG3 28 0.41 18.12 4.75 90.48
108 INT202975 Regulation of Regulation of STC2 1 0.01 1.08 0.36 90.48
109 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 90.44
110 INT129303 Positive_regulation of NAV1 54 0.70 36.92 57.45 90.32
111 INT131610 Gene_expression of scat 2 0.59 0.98 0 90.32
112 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21 90.24
113 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 89.88
114 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 89.88
115 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 89.12
116 INT294635 Binding of Bh4p 1 0.01 0.49 0.04 88.84
117 INT17741 Gene_expression of MBP 67 0.78 23.67 9.65 88.72
118 INT194242 Positive_regulation of Gene_expression of MBP 9 0.45 4.1 1.71 88.72
119 INT207774 Gene_expression of Pacsin1 1 0.04 6.32 0.84 88.56
120 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 88.32
121 INT99508 Regulation of Bcl2l1 12 0.61 10.44 2.71 88.08
122 INT14916 Binding of RASA1 15 0.37 13.64 1.44 87.88
123 INT82168 Positive_regulation of S100b 20 0.68 9.72 3.08 87.48
124 INT135894 Gene_expression of SSH1 2 0.59 1.7 0.33 87.12
125 INT114013 Binding of ATP1A2 3 0.47 3.51 1.46 87.04
126 INT111067 Positive_regulation of Gene_expression of Psen1 32 0.68 21.2 4.19 86.00
127 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 85.64
128 INT65500 Gene_expression of App 605 0.78 429.94 98.31 85.56
129 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 85.36
130 INT166296 Regulation of Gene_expression of PCS 3 0.27 1.89 0.36 85.32
131 INT48437 Positive_regulation of SH3BP5 4 0.20 2.41 3.09 85.04
132 INT4060 Gene_expression of Bche 17 0.70 5.23 6.59 84.40
133 INT33957 Positive_regulation of OPRL1 14 0.68 2.89 9.72 84.28
134 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 83.92
135 INT15470 Regulation of CPP 42 0.48 26.1 18.25 83.76
136 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 83.76
137 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 83.12
138 INT125556 Gene_expression of SLC4A4 2 0.14 2.28 0 83.08
139 INT92243 Binding of F13a1 3 0.31 1.79 0.19 83.04
140 INT108535 Positive_regulation of TNNI1 7 0.67 5.54 2.12 82.88
141 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 82.84
142 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 82.76
143 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 82.76
144 INT78710 Positive_regulation of GPKOW 2 0.01 2.06 1.59 82.12
145 INT63042 Binding of Apoe 59 0.48 31.23 5.88 82.04
146 INT143006 Gene_expression of A1BG 23 0.73 22.92 0.88 81.96
147 INT131748 Binding of Csad 5 0.32 5.23 3.32 81.76
148 INT101140 Negative_regulation of Tap1 7 0.50 9.08 17.46 81.60
149 INT230271 Transcription of DIXDC1 1 0.20 1.24 0 81.40
150 INT46088 Localization of F3 15 0.37 13.7 2.23 81.36
151 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 81.32
152 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 81.32
153 INT38859 Gene_expression of SGSM3 14 0.75 12.98 4.09 81.12
154 INT75530 Regulation of SGSM3 11 0.60 7.22 4.48 81.12
155 INT199413 Negative_regulation of OR3A4P 2 0.01 0.32 0.07 81.08
156 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 80.24
157 INT104000 Phosphorylation of Grin2b 73 0.82 48.34 93.48 79.48
158 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 79.00
159 INT3201 Positive_regulation of F9 11 0.49 5.12 0.56 78.64
160 INT62815 Binding of Gnl3 1 0.41 0.56 0.24 77.84
161 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17 77.60
162 INT37649 Gene_expression of Fbp1 4 0.49 3.16 1.84 76.72
163 INT717 Regulation of F2 29 0.61 17.46 6.99 76.28
164 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 75.72
165 INT812 Localization of INS 1026 0.81 515.6 145.31 75.40
166 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 75.36
167 INT145858 Positive_regulation of fh 1 0.00 1.46 0.08 75.00
168 INT28774 Localization of LAMC2 6 0.73 3.2 0.76 75.00
169 INT2532 Negative_regulation of Cebpz 98 0.00 53.06 28.57 74.64
170 INT2531 Positive_regulation of Cebpz 166 0.00 43.08 38.86 74.64
171 INT4651 Gene_expression of Cebpz 39 0.00 20.19 8.5 74.64
172 INT160827 Positive_regulation of Gene_expression of Cebpz 2 0.42 1.61 0.59 74.64
173 INT97171 Localization of Ear1 7 0.43 4.25 0.44 74.48
174 INT230779 Negative_regulation of Positive_regulation of MCRS1 2 0.04 3.78 0.92 74.32
175 INT255432 Binding of SAG 3 0.35 1.41 0.16 74.20
176 INT79805 Phosphorylation of PRKCA 57 0.81 23.33 20.41 73.76
177 INT52714 Regulation of PRKCA 28 0.61 7.73 13.66 73.76
178 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 73.76
179 INT3911 Gene_expression of TNFAIP1 29 0.65 21.68 1.85 73.76
180 INT5536 Regulation of NA 74 0.59 16.61 15.36 73.52
181 INT99506 Negative_regulation of Bcl2l1 25 0.58 15.7 6.09 73.20
182 INT37834 Negative_regulation of Positive_regulation of CPP 14 0.58 6.22 5.69 72.88
183 INT14960 Positive_regulation of Serpinc1 17 0.68 12.71 3.02 71.92
184 INT39635 Negative_regulation of Positive_regulation of Serpinc1 2 0.28 1.93 0.07 71.92
185 INT14599 Localization of Tpsab1 36 0.79 14.58 7.18 71.92
186 INT299196 Transcription of Thy1 1 0.66 1.98 0 71.68
187 INT90545 Phosphorylation of Siglec1 53 0.11 12.09 6.81 71.56
188 INT64180 Binding of Apoc4 2 0.33 3.03 0.23 71.28
189 INT14600 Positive_regulation of Tpsab1 51 0.68 22.1 7.7 71.20
190 INT319339 Localization of ZBP1 3 0.18 3.09 0.2 70.64
191 INT7035 Regulation of CGA 87 0.45 29.04 28.45 70.28
192 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 70.20
193 INT123595 Regulation of Snca 7 0.62 4.3 3.06 70.16
194 INT317296 Regulation of YWHAQ 1 0.44 1.99 0.13 70.16
195 INT317297 Regulation of SNCAIP 1 0.19 1.99 0.13 70.16
196 INT163133 Gene_expression of ZBP1 28 0.65 18.59 1.25 69.08
197 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 68.76
198 INT188758 Negative_regulation of CPM 2 0.05 0.89 0 68.76
199 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65 68.56
200 INT305619 Negative_regulation of Regulation of MCRS1 1 0.04 1.35 0.35 68.24
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