D:Headache

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pChart

Disease Term
Synonyms Adhd Alzheimer S Disease Migraine, Atypical Facial Pain, Bilateral Headache, Bilateral Headaches, CEPHALALGIA, CEPHALALGIAS, Cephalgia, Cephalgias, CEPHALODYNIA, Cephalodynias, Cranial Pain
Documents 53549
Hot Single Events 200
Hot Interactions 167

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Headache. They are ordered first by their relevance to Headache and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59 100.00
2 INT142661 Binding of IFIT1 and NPY2R 1 0.00 2.49 1.08 100.00
3 INT127778 Mthfd1 Regulation of Positive_regulation of Mthfr 1 0.01 0.71 0.62 100.00
4 INT132442 Binding of RHAG and EFHC1 1 0.36 1.2 0.51 100.00
5 INT132443 Binding of MEP1A and EFHC1 1 0.44 1.19 0.5 100.00
6 INT124918 Binding of PLEK and Maob 1 0.10 1.05 0.98 100.00
7 INT147232 Binding of tn and Cpe 1 0.03 1.55 0.95 100.00
8 INT302511 Binding of OPA1 and Nos3 1 0.02 1.57 0.1 100.00
9 INT176010 Binding of MTHFR and ZNF677 1 0.00 0.7 0.5 99.76
10 INT140571 Ifng Positive_regulation of Ifnb1 1 0.01 0.82 0.36 99.64
11 INT140575 Il6 Positive_regulation of Ifnb1 1 0.02 0.82 0.36 99.64
12 INT140573 Positive_regulation of Ifng Positive_regulation of Ifnb1 1 0.01 0.83 0.36 99.64
13 INT146997 Binding of PLXNA3 and RLS 1 0.36 0.47 0.1 99.58
14 INT251729 Binding of FEN1 and EXOSC1 1 0.19 1.13 0.74 99.36
15 INT58745 CPP Positive_regulation of Localization of Prl 1 0.01 0.92 1.06 99.32
16 INT140569 Ifng Positive_regulation of Gene_expression of Il6 1 0.00 0.82 0.36 99.16
17 INT140572 Ifng Positive_regulation of Gene_expression of Ifnb1 1 0.01 0.82 0.36 99.16
18 INT130948 Amt Regulation of Gene_expression of LEP 1 0.00 1.04 0.78 99.12
19 INT158762 Binding of Vwf and Mthfr 1 0.05 1.85 1.37 99.04
20 INT143166 C1orf61 Regulation of Transcription of HTR1A 1 0.30 0.51 0.35 98.96
21 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37 98.92
22 INT108729 Binding of CACNA1A and Cacna1a 3 0.13 1.21 0.95 98.92
23 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26 98.90
24 INT170653 Ngf Regulation of Csf2 1 0.34 1.11 1.05 98.88
25 INT130949 Amt Regulation of LEP 1 0.00 1.04 0.77 98.84
26 INT140574 Ifnb1 Positive_regulation of Il6 1 0.05 0.9 0.39 98.56
27 INT70227 Binding of Calca and B3GAT1 1 0.36 0.35 0.42 98.52
28 INT46308 Asrgl1 Positive_regulation of Gene_expression of Serpinc1 1 0.01 1.07 0.19 98.48
29 INT46306 Asrgl1 Positive_regulation of Negative_regulation of Plg 1 0.01 1.07 0.19 98.48
30 INT46307 Asrgl1 Positive_regulation of Negative_regulation of Serpinc1 1 0.01 1.07 0.19 98.48
31 INT165305 CSF2 Positive_regulation of Localization of CCBE1 1 0.06 1.34 0.35 98.32
32 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47 97.88
33 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67 97.84
34 INT347962 Cpox Negative_regulation of Positive_regulation of Nos1 1 0.02 0.59 0.67 97.76
35 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36 97.64
36 INT77753 Abnormal Regulation of CACNA1S 1 0.00 0.78 0.28 97.48
37 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87 97.28
38 INT111134 Binding of Krit1 and Rap1a 1 0.07 0.81 0.1 97.28
39 INT94203 SP5 Positive_regulation of FOS 1 0.25 1.41 1.72 97.20
40 INT145098 NGF Positive_regulation of BDNF 1 0.66 1.33 1.67 96.88
41 INT147936 CGA Regulation of Gene_expression of FSHR 1 0.31 0.71 0.1 96.80
42 INT96563 Binding of ADRA1D and UCN2 1 0.19 1.34 0.1 96.56
43 INT306067 Binding of ADH5 and CYLD 1 0.02 3.13 0.19 96.52
44 INT117504 OPA1 Positive_regulation of CPP 1 0.09 1.09 1.13 96.52
45 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3 96.20
46 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29 96.20
47 INT99241 IFNG Regulation of IL1B 2 0.21 1.26 0.14 96.20
48 INT99242 IFNG Regulation of IL8 1 0.23 0.57 0.1 96.20
49 INT99243 IFNG Regulation of HLA-DRA 1 0.25 0.57 0.1 96.20
50 INT119546 Nfe2l2 Regulation of Gene_expression of Fos 1 0.48 0.94 0.52 96.08
51 INT119548 Fos Regulation of Gene_expression of Nfe2l2 1 0.48 0.47 0.25 96.08
52 INT311046 Binding of CSF2 and IL33 1 0.00 1.86 0.26 96.04
53 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48 95.92
54 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48 95.92
55 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4 95.92
56 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 95.84
57 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95 95.68
58 INT94204 NCOR2 Regulation of Gene_expression of SP5 1 0.02 2.15 3.12 95.60
59 INT94205 TACR1 Regulation of Gene_expression of SP5 1 0.04 0.72 1.06 95.60
60 INT94206 SP5 Regulation of Gene_expression of FOS 1 0.22 0.7 0.98 95.60
61 INT322810 SLC12A1 Regulation of Binding of GRIA1 1 0.00 0.39 0.36 95.44
62 INT104162 HTR1D Regulation of Localization of CALCA 1 0.31 0.28 0.58 95.28
63 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06 94.96
64 INT118136 Binding of HTR1A and HTR2A 1 0.36 0.77 0.45 94.92
65 INT56904 Binding of GCY and ICA1 1 0.15 1.5 0.28 94.88
66 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2 94.80
67 INT148773 Binding of Calca and Usf2 1 0.46 0.42 0.64 94.60
68 INT148776 Binding of Usf2 and Rtn1 1 0.38 0.42 0.64 94.60
69 INT36571 MDK Positive_regulation of Localization of PRL 1 0.04 0.19 0.29 94.56
70 INT114389 Csf3 Negative_regulation of Localization of Tnf 1 0.02 0.46 0.26 94.48
71 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41 94.00
72 INT142994 Binding of UPF1 and FCMTE1 1 0.00 0.91 0.7 93.68
73 INT166496 ADCYAP1 Positive_regulation of Positive_regulation of RTCA 1 0.02 0.09 0 93.52
74 INT166497 RTCA Positive_regulation of ADCYAP1 1 0.02 0.09 0 93.52
75 INT251730 Binding of CD70 and SUGT1 1 0.01 0.85 0.49 93.44
76 INT251731 Binding of CD70 and SNRNP70 1 0.04 0.84 0.49 93.44
77 INT142507 Binding of Calca and Ramp1 1 0.31 0.48 0.73 93.04
78 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56 92.92
79 INT169118 PLAU Regulation of Gene_expression of CSF2 1 0.41 0.49 0.17 92.84
80 INT62059 Positive_regulation of SCN5A Positive_regulation of Gene_expression of FOS 1 0.01 0.42 0.66 92.72
81 INT124877 Gnat3 Negative_regulation of FOS 1 0.09 0.15 0.82 92.72
82 INT124876 Gnat3 Negative_regulation of Positive_regulation of FOS 1 0.09 0.15 0.82 92.72
83 INT169117 PLAU Regulation of Gene_expression of MMP9 1 0.47 0.49 0.17 92.68
84 INT10739 IL3 Positive_regulation of CRP 1 0.18 1.14 0.09 92.60
85 INT10740 IL3 Positive_regulation of TNF 1 0.29 1.14 0.09 92.60
86 INT87061 Binding of AVP and IL6 1 0.26 1.04 0.22 92.52
87 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41 92.40
88 INT326514 Sugt1 Negative_regulation of MTHFR 1 0.01 0.77 0.42 92.32
89 INT26230 Binding of GSR and HTR1D 1 0.12 0.15 0.69 92.32
90 INT114388 Csf3 Negative_regulation of Tnf 1 0.02 0.46 0.25 92.24
91 INT114390 Regulation of Csf3 Negative_regulation of Tnf 1 0.02 0.46 0.25 92.24
92 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 92.20
93 INT19905 Trh Regulation of Gnrhr 1 0.00 0.25 0.22 92.20
94 INT196699 Binding of Cog1 and Rbm39 1 0.00 1.85 0.09 92.12
95 INT176009 Binding of GRHPR and ZNF677 1 0.00 0.57 0.36 92.08
96 INT95125 Binding of KCNA6 and SGCG 1 0.40 2.73 0.18 91.92
97 INT117531 Twist1 Regulation of CSAD 1 0.00 0.85 0.47 91.84
98 INT69494 GH1 Regulation of Localization of Prl 1 0.01 0.46 0.14 91.80
99 INT145592 Vamp1 Positive_regulation of Calca 1 0.01 0.28 0.73 91.64
100 INT26231 Binding of GSR and HTR1B 1 0.12 0.15 0.66 91.56
101 INT26235 Binding of GSR and Htr1a 1 0.12 0.09 0.31 91.24
102 INT7869 Gh Negative_regulation of IGF1 1 0.39 0.47 0.23 91.00
103 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17 90.72
104 INT92088 ASNA1 Positive_regulation of Localization of POMC 1 0.00 0.97 0.13 90.36
105 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 90.28
106 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 90.24
107 INT19906 Positive_regulation of Trh Regulation of Prl 2 0.04 0.47 0.43 90.04
108 INT92089 ASNA1 Positive_regulation of POMC 1 0.00 0.97 0.13 89.96
109 INT160602 Binding of ABL2 and ADH1B 1 0.40 0.36 0 89.64
110 INT134487 Positive_regulation of TGFBI Positive_regulation of Ltp 1 0.03 1.19 1.11 89.40
111 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48 89.08
112 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 88.92
113 INT322812 Binding of SLC12A1 and MOCOS 1 0.00 1.69 1.49 88.64
114 INT158211 TNFSF14 Positive_regulation of Gene_expression of TNF 1 0.03 0.35 0.23 88.20
115 INT140493 GH1 Regulation of Prl 1 0.18 0.47 0.33 88.04
116 INT140487 GH1 Regulation of STH 1 0.21 0.23 0.16 88.04
117 INT320633 Positive_regulation of MAPK1 Regulation of BCL2 1 0.04 1.21 0.7 87.00
118 INT320634 Positive_regulation of MAPK1 Regulation of PBX2 1 0.03 1.21 0.7 87.00
119 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85 86.96
120 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 86.88
121 INT193480 Binding of ABCA1 and IRF6 1 0.00 1.08 0.46 86.60
122 INT148594 Binding of BCL2 and CD34 1 0.39 1.17 0.13 86.48
123 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 86.36
124 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 86.36
125 INT88252 Binding of RAP1A and Krit1 1 0.36 2.25 0.33 86.16
126 INT319581 Binding of PIAS1 and TNFSF14 1 0.02 1.58 2.13 86.08
127 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77 85.92
128 INT149541 Binding of GCA and TADA1 1 0.40 1.4 0.13 85.80
129 INT12522 Binding of FSHR and POMC 1 0.33 3.89 0.34 85.76
130 INT12525 Binding of POMC and GANAB 1 0.04 1.9 0.17 85.76
131 INT12524 Binding of LHB and POMC 1 0.12 1.96 0.17 85.76
132 INT12521 Binding of PLOD1 and POMC 1 0.26 1.96 0.17 85.76
133 INT12523 Binding of FSHR and LHB 1 0.11 0.98 0.09 85.76
134 INT12520 Binding of FSHR and GANAB 1 0.03 0.97 0.09 85.76
135 INT322811 Binding of GRIA1 and RS1 1 0.00 0.43 0.51 85.48
136 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85 85.40
137 INT96783 Positive_regulation of Binding of CALCA and Calca 1 0.29 0.17 0.77 85.40
138 INT151783 Regulation of Binding of Calca and P2rx1 1 0.42 0.51 0.64 85.32
139 INT322808 Binding of RS1 and MOCOS 1 0.00 0.86 1.01 85.20
140 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51 85.20
141 INT124878 Gnat3 Negative_regulation of Gene_expression of FOS 1 0.09 0.16 0.85 84.96
142 INT277835 EPO Positive_regulation of Localization of VEGFA 1 0.03 1.36 0.08 84.72
143 INT151778 Binding of Calca and P2rx1 1 0.35 0.5 0.64 84.68
144 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79 84.64
145 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5 84.60
146 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69 84.56
147 INT139271 Binding of CRH and POMC 1 0.35 1.1 0.22 84.52
148 INT248310 Crx Regulation of MATN3 1 0.07 0.65 0.45 84.44
149 INT169346 Nxn Negative_regulation of Dynll1 1 0.06 1.22 1.87 83.48
150 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41 83.32
151 INT156438 Cpox Positive_regulation of Nos2 3 0.14 1.24 0.4 83.04
152 INT156439 Positive_regulation of Cpox Positive_regulation of Nos2 1 0.14 0.52 0.28 83.04
153 INT156440 Cpox Positive_regulation of NOS1 1 0.01 0.52 0.28 83.04
154 INT35201 Trh Regulation of Tshb 1 0.01 0.28 0.39 82.96
155 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77 82.92
156 INT148780 Binding of Usf2 and Usf1 1 0.40 0.41 0.62 82.92
157 INT41659 IL31RA Regulation of PRL 1 0.22 1.07 0.98 82.80
158 INT41658 IL31RA Regulation of GH1 1 0.09 1.07 0.98 82.80
159 INT280181 Pde5a Positive_regulation of Regulation of Cpox 1 0.00 0.16 0.26 82.40
160 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5 81.92
161 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 81.12
162 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 80.84
163 INT70478 Binding of HTR1F and PIGA 1 0.33 0.33 0.52 80.68
164 INT138424 Binding of RAMP1 and Calca 1 0.01 0.08 0.47 80.52
165 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43 80.40
166 INT118824 OPA1 Positive_regulation of Gene_expression of Nos1 2 0.03 0.24 0.65 80.28
167 INT157142 OPA1 Positive_regulation of Gene_expression of Camk2a 1 0.02 0.3 1.02 80.12
168 INT24660 Positive_regulation of Binding of ELANE and SERPINA1 1 0.17 0.73 0.08 79.84
169 INT24659 Binding of ELANE and SERPINA1 1 0.13 0.73 0.08 79.84
170 INT151780 Calca Positive_regulation of Camkk2 1 0.01 0.48 0.61 79.76
171 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28 79.20
172 INT311612 Binding of Drd2 and Sert1 1 0.12 0.65 0.86 78.76
173 INT142709 Binding of TWIST1 and CEBPZ 2 0.17 1.16 0.95 78.44
174 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38 78.28
175 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 77.92
176 INT108066 Binding of NTRK1 and Ngf 3 0.33 2.56 1.66 77.80
177 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2 77.80
178 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2 77.80
179 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19 77.80
180 INT36008 Negative_regulation of Binding of Drd2 and Prl 1 0.01 2.11 0.85 77.16
181 INT158199 Negative_regulation of Binding of ICAM1 and AHSA1 1 0.15 0.3 0.2 76.84
182 INT158212 Negative_regulation of Binding of CCR1 and AHSA1 1 0.20 0.3 0.2 76.84
183 INT158204 Negative_regulation of Binding of MAPK1 and CCR2 1 0.22 0.3 0.2 76.84
184 INT158198 Negative_regulation of Binding of AHSA1 and CCR2 1 0.21 0.3 0.2 76.84
185 INT158227 Negative_regulation of Binding of ICAM1 and MAPK1 1 0.16 0.3 0.2 76.84
186 INT158228 Negative_regulation of Binding of MAPK1 and TNFSF14 1 0.04 0.3 0.2 76.84
187 INT158216 Negative_regulation of Binding of TNFSF14 and CCR2 1 0.06 0.3 0.2 76.84
188 INT158229 Negative_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2 76.84
189 INT158230 Negative_regulation of Binding of CCR1 and TNFSF14 1 0.06 0.3 0.2 76.84
190 INT158202 Negative_regulation of Binding of TNFSF14 and AHSA1 1 0.03 0.3 0.2 76.84
191 INT158219 Negative_regulation of Binding of CCR1 and MAPK1 1 0.21 0.3 0.2 76.84
192 INT58588 IFNG Positive_regulation of ARHGAP4 1 0.31 1.22 0.19 76.72
193 INT158208 Binding of MAPK1 and TNFSF14 1 0.03 0.3 0.2 76.52
194 INT158214 Positive_regulation of Binding of TNFSF14 and AHSA1 1 0.04 0.3 0.2 76.52
195 INT158203 TNFSF14 Positive_regulation of AHSA1 1 0.04 0.3 0.2 76.52
196 INT158220 Positive_regulation of Binding of ICAM1 and TNFSF14 1 0.05 0.3 0.2 76.52
197 INT158207 Positive_regulation of Binding of TNFSF14 and CCR2 1 0.07 0.3 0.2 76.52
198 INT158223 Binding of ICAM1 and TNFSF14 1 0.04 0.3 0.2 76.52
199 INT158231 TNFSF14 Positive_regulation of CCR1 1 0.07 0.3 0.2 76.52
200 INT158232 Positive_regulation of Binding of MAPK1 and TNFSF14 1 0.04 0.3 0.2 76.52

Single Events

The table below shows the top 200 pain related interactions that have been reported for Headache. They are ordered first by their pain relevance and then by number of times they were reported in Headache. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 100.00
2 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 100.00
3 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 100.00
4 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 100.00
5 INT36428 Binding of Chdh 42 0.47 48.04 26.54 100.00
6 INT22909 Positive_regulation of Chdh 26 0.68 28.69 16.13 100.00
7 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 100.00
8 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
9 INT138833 Binding of MTHFR 12 0.46 16.08 6.4 100.00
10 INT75742 Binding of RLS 86 0.42 95.27 19.04 100.00
11 INT6761 Binding of CALCA 100 0.48 26.71 62.05 100.00
12 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 100.00
13 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1 100.00
14 INT17997 Positive_regulation of Mch 23 0.49 12.71 6.67 100.00
15 INT46695 Positive_regulation of TNC 28 0.67 17.06 12.04 100.00
16 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 100.00
17 INT163682 Phosphorylation of tn 1 0.09 4.25 3.96 100.00
18 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65 100.00
19 INT52115 Positive_regulation of tn 5 0.50 4.68 3.54 100.00
20 INT1530 Regulation of Gh 382 0.61 115.96 112.47 100.00
21 INT356350 Positive_regulation of Snf8 1 0.02 4.31 4.23 100.00
22 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 100.00
23 INT121954 Binding of Mthfr 17 0.44 13.47 4.66 100.00
24 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 100.00
25 INT75765 Positive_regulation of Gene_expression of Cacna1a 17 0.70 17.51 10.91 100.00
26 INT152030 Gene_expression of Postn 10 0.55 8.09 7.08 100.00
27 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 100.00
28 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35 100.00
29 INT43931 Binding of CFH 49 0.48 31.85 3.96 100.00
30 INT117500 Gene_expression of Adipoq 90 0.74 67.79 16.58 100.00
31 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 100.00
32 INT1026 Binding of Lbp 207 0.48 150.96 119.16 100.00
33 INT2844 Positive_regulation of ID1 6 0.70 3.92 2.03 100.00
34 INT24724 Positive_regulation of Gene_expression of SST 11 0.67 7.51 6.12 100.00
35 INT144632 Regulation of Acads 1 0.27 2.63 2.64 100.00
36 INT85301 Gene_expression of Ndp 6 0.52 4.19 4.5 100.00
37 INT27627 Binding of Rac1 41 0.41 22.88 13.68 100.00
38 INT46620 Positive_regulation of Positive_regulation of CSF1 1 0.12 2.9 2.94 100.00
39 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 100.00
40 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08 100.00
41 INT252383 Negative_regulation of Positive_regulation of NCF4 1 0.57 2.18 2.08 100.00
42 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
43 INT5913 Binding of OPA1 12 0.41 9.33 2.92 100.00
44 INT88197 Binding of ZAK 9 0.46 6.23 3.54 100.00
45 INT114734 Localization of ANTXR2 5 0.73 3.28 1.62 100.00
46 INT17839 Binding of PIH 2 0.37 4.29 1.52 100.00
47 INT67697 Regulation of Pst 6 0.18 3.19 2.04 100.00
48 INT32579 Binding of C4B 14 0.36 14.99 7.79 100.00
49 INT64523 Binding of Ndp 10 0.33 2.72 7.29 100.00
50 INT79168 Binding of TNC 39 0.47 16.51 7.55 100.00
51 INT81154 Gene_expression of HCRT 10 0.75 5.32 2.22 100.00
52 INT69944 Positive_regulation of Ndp 7 0.38 4.81 5.6 100.00
53 INT47690 Regulation of Bdnf 118 0.62 53.02 64.5 100.00
54 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 100.00
55 INT140084 Regulation of Cfh 1 0.53 1.03 1.03 100.00
56 INT53460 Gene_expression of tn 13 0.66 7.97 5.2 100.00
57 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2 100.00
58 INT68017 Gene_expression of Ea2 4 0.23 3.15 2.11 100.00
59 INT131044 Binding of tn 2 0.30 2.58 1.93 100.00
60 INT23104 Positive_regulation of Cga 20 0.70 10.35 8.03 100.00
61 INT160738 Positive_regulation of Cyth1 2 0.41 3.67 2.22 100.00
62 INT123903 Gene_expression of ATXN3 7 0.75 6.71 1.85 100.00
63 INT21492 Binding of Scn1a 4 0.37 2.36 2.04 100.00
64 INT62570 Binding of Pth 48 0.48 26.45 4.85 100.00
65 INT158070 Localization of Aes 23 0.65 19.93 10.9 100.00
66 INT90210 Regulation of tn 1 0.23 1.93 1.46 100.00
67 INT156294 Binding of Hm 2 0.07 1.7 0.86 100.00
68 INT79166 Regulation of TNC 12 0.44 9.42 8.13 100.00
69 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13 100.00
70 INT144781 Gene_expression of Etax2 1 0.01 1.68 1.09 100.00
71 INT37037 Positive_regulation of ANTXR2 6 0.50 5.75 1.56 100.00
72 INT144782 Gene_expression of LY6E 2 0.01 1.67 1.12 100.00
73 INT251744 Binding of GATA4 1 0.36 1.55 0.96 100.00
74 INT216065 Localization of C4B 2 0.21 2.86 2.01 100.00
75 INT99287 Binding of GOLPH3 6 0.35 2.87 0.85 100.00
76 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 100.00
77 INT2774 Binding of Crp 241 0.48 195.89 44.39 100.00
78 INT50669 Negative_regulation of Ptn 15 0.58 5.56 6.88 100.00
79 INT68115 Binding of LPCAT3 1 0.27 1.28 0.8 100.00
80 INT135629 Binding of COMT 33 0.48 16.68 19.37 100.00
81 INT39357 Binding of Afp 5 0.48 3.58 0.85 100.00
82 INT17996 Binding of Crp 40 0.37 31.4 7.8 100.00
83 INT28094 Binding of PTH 29 0.37 13.57 3.09 100.00
84 INT79167 Localization of TNC 8 0.78 4.15 1.44 100.00
85 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 100.00
86 INT142662 Binding of IFIT1 2 0.02 2.26 0.66 100.00
87 INT142663 Binding of NPY2R 1 0.01 1.24 0.54 100.00
88 INT14831 Negative_regulation of TNC 18 0.50 8.71 4.61 100.00
89 INT17998 Gene_expression of Mch 29 0.58 7.76 1.37 100.00
90 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 100.00
91 INT39948 Binding of FLNA 45 0.42 58.05 4.27 100.00
92 INT77371 Regulation of Regulation of Cebpz 4 0.45 0.45 2.42 100.00
93 INT132278 Binding of CTLA4 32 0.39 18.69 8.17 100.00
94 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 100.00
95 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 100.00
96 INT21660 Regulation of CHM 14 0.61 8.51 0.93 100.00
97 INT81262 Positive_regulation of Phlda2 9 0.43 3.76 2.47 100.00
98 INT165056 Regulation of Gene_expression of MID1 2 0.39 0.93 1.1 100.00
99 INT20462 Binding of ESR1 210 0.44 102.7 26.34 100.00
100 INT140085 Binding of Gm2014 1 0.00 0.61 0.5 100.00
101 INT151255 Negative_regulation of Olr1347 1 0.01 0.75 0.35 100.00
102 INT34830 Regulation of PGR 14 0.45 6.99 2.32 100.00
103 INT162831 Regulation of ARSD 13 0.35 6.17 1.19 100.00
104 INT9080 Regulation of PPBP 17 0.44 5.75 4.3 100.00
105 INT29 Negative_regulation of Gast 74 0.59 24.85 24.96 100.00
106 INT176013 Negative_regulation of Binding of MTHFR 2 0.42 1.18 0.63 100.00
107 INT15610 Localization of GOPC 223 0.65 68.26 28.7 100.00
108 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 100.00
109 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
110 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51 100.00
111 INT178754 Positive_regulation of Localization of GOPC 32 0.43 10.1 4.73 100.00
112 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 100.00
113 INT94046 Protein_catabolism of Cacna1a 1 0.70 0.83 0.9 100.00
114 INT4857 Regulation of Tacr1 115 0.62 39.01 84.52 100.00
115 INT115295 Gene_expression of SPERT 1 0.00 0.59 0.59 100.00
116 INT51646 Binding of IL3 3 0.37 3.26 0.56 100.00
117 INT45234 Binding of Ldha 20 0.37 9.8 8.18 100.00
118 INT59718 Regulation of Htr1a 10 0.44 3.9 5.44 100.00
119 INT45674 Regulation of Gene_expression of Serpina6 3 0.14 0.86 1.14 100.00
120 INT63673 Positive_regulation of Binding of Ldha 2 0.44 1.91 0.9 100.00
121 INT189813 Negative_regulation of CACNA1A 4 0.57 3.07 0.55 100.00
122 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 100.00
123 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 99.98
124 INT135568 Localization of CHM 5 0.65 6.51 1.76 99.98
125 INT5710 Negative_regulation of Localization of Lhb 146 0.57 20.51 58.33 99.98
126 INT30961 Binding of HTR2A 33 0.47 11.44 12.86 99.98
127 INT70958 Binding of NOS3 19 0.37 11.84 3.29 99.98
128 INT186509 Regulation of MOCOS 1 0.02 0.69 0.29 99.98
129 INT18660 Binding of Gnrhr 45 0.41 10.6 16.85 99.98
130 INT83602 Positive_regulation of Gene_expression of TRPV1 114 0.70 51.19 56.35 99.98
131 INT425 Localization of PRL 455 0.81 189.64 144.8 99.96
132 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.96
133 INT34742 Gene_expression of Gnat3 44 0.67 6.83 5.65 99.96
134 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 99.96
135 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 99.96
136 INT11377 Positive_regulation of Ngf 331 0.70 206.5 238 99.96
137 INT50039 Positive_regulation of Il4 48 0.55 34.8 23.34 99.96
138 INT50038 Positive_regulation of Il5 11 0.41 6.89 3.49 99.96
139 INT162783 Binding of LIFR 1 0.36 1.52 0.86 99.96
140 INT69303 Positive_regulation of Gene_expression of Il4 27 0.68 20.01 14.8 99.96
141 INT76416 Positive_regulation of Gene_expression of Il5 9 0.08 4.16 1.65 99.96
142 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 99.96
143 INT3118 Negative_regulation of Positive_regulation of POMC 33 0.59 9.42 18.07 99.96
144 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.92
145 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.92
146 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.92
147 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 99.92
148 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 99.92
149 INT11375 Negative_regulation of Es2 10 0.50 6.52 5.64 99.92
150 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 99.92
151 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.92
152 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 99.92
153 INT3793 Regulation of CEBPZ 59 0.61 20.91 15.83 99.92
154 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 99.92
155 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.92
156 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.92
157 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.92
158 INT217875 Gene_expression of AD5 41 0.40 19.85 2.28 99.92
159 INT67682 Localization of Bdnf 204 0.81 72.36 88.92 99.92
160 INT47683 Negative_regulation of Bdnf 92 0.59 47.53 43.55 99.92
161 INT75434 Gene_expression of Il13 27 0.52 26.19 15.4 99.92
162 INT217864 Positive_regulation of Gene_expression of AD5 4 0.30 3.51 0.53 99.92
163 INT115294 Regulation of Regulation of TPH1 2 0.10 1 0.98 99.92
164 INT61011 Regulation of TPH1 4 0.22 1.17 2.09 99.92
165 INT100542 Regulation of Ppig 6 0.17 11.78 0.69 99.92
166 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25 99.92
167 INT252382 Regulation of Positive_regulation of NCF4 1 0.38 2.6 2.64 99.90
168 INT80901 Localization of Cts 2 0.58 2.04 1.68 99.90
169 INT76523 Transcription of HPSE2 1 0.03 0.78 0.6 99.90
170 INT65536 Negative_regulation of Positive_regulation of Nfkb1 77 0.59 38.86 33.33 99.90
171 INT626 Localization of CALCA 289 0.81 125.39 221.15 99.88
172 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 99.88
173 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 99.88
174 INT13354 Transcription of TNF 108 0.72 85.81 42.32 99.88
175 INT3244 Negative_regulation of eCB 37 0.03 16.69 12.61 99.88
176 INT13432 Positive_regulation of Klkb1 23 0.57 5.36 8.65 99.88
177 INT27936 Positive_regulation of Gene_expression of Klkb1 5 0.41 1.28 1.75 99.88
178 INT27937 Gene_expression of Klkb1 35 0.55 1.86 10.08 99.88
179 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 99.86
180 INT31809 Gene_expression of HTR2B 5 0.75 2.3 2.44 99.86
181 INT14726 Gene_expression of Mag 8 0.42 8.23 5 99.86
182 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.84
183 INT2541 Binding of Calca 200 0.48 67.14 134.62 99.84
184 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57 99.84
185 INT47459 Gene_expression of Rac1 101 0.68 45.27 24.33 99.84
186 INT11069 Positive_regulation of Pf4 35 0.68 27.7 13.96 99.84
187 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.84
188 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.84
189 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 99.84
190 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.84
191 INT46168 Positive_regulation of Sepp1 12 0.50 8.02 7.47 99.84
192 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 99.84
193 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.84
194 INT233111 Negative_regulation of Etfdh 7 0.33 9.1 5.48 99.84
195 INT23212 Positive_regulation of Rac1 46 0.55 32.85 15.1 99.84
196 INT62826 Negative_regulation of Gene_expression of ICAM1 75 0.58 46.39 17.72 99.84
197 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 99.84
198 INT9900 Positive_regulation of Vwf 80 0.69 51.85 18.13 99.84
199 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 99.84
200 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 99.84
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