D:Hearing Disorder

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pChart

Disease Term
Synonyms Auditory Alteration, Auditory Defect, Auditory Disturbance, AUDITORY EFFECTS, Auditory Perceptual Alterations, Auditory Sensory Alterations, Auditory System Disease, Auditory System Syndrome, Disorder Of Auditory System, DISTORTED HEARING, DYSACUSIS
Documents 85
Hot Single Events 5
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hearing Disorder. They are ordered first by their relevance to Hearing Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT261976 Binding of PDCD1 and SUGT1 1 0.00 1.3 0.25 97.84
2 INT261977 Binding of HLA-A and PDCD1 1 0.07 0.52 0 70.80
3 INT261978 Binding of HLA-DRB4 and PDCD1 1 0.23 0.51 0 70.16
4 INT203040 Binding of PDCD1 and PDCD1LG2 3 0.40 4.86 0.98 5.00
5 INT203046 Binding of PDCD1 and CD274 2 0.40 3.97 0.68 5.00
6 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
7 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hearing Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Hearing Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.00
2 INT310680 Gene_expression of ARSB 1 0.64 6.28 0.12 86.72
3 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 83.92
4 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 83.56
5 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 81.68
6 INT49025 Positive_regulation of TYR 14 0.69 7.15 5.84 70.00
7 INT203050 Binding of PDCD1 12 0.48 12.93 4.5 68.24
8 INT19331 Positive_regulation of HLA-A 12 0.49 7.72 3.28 60.88
9 INT37679 Positive_regulation of HLA-DRB4 12 0.34 11.93 1.16 60.88
10 INT39344 Gene_expression of DNASE1L3 12 0.54 2.25 2.88 57.96
11 INT288289 Positive_regulation of Cm3 3 0.09 0.74 0 56.40
12 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 52.88
13 INT282818 Negative_regulation of DNASE1L3 1 0.13 0.1 0.06 52.84
14 INT2416 Negative_regulation of MAOA 92 0.59 42.24 36.5 49.76
15 INT86371 Protein_catabolism of Pnoc 2 0.98 0.79 3.65 49.60
16 INT282819 Localization of DNASE1L3 1 0.24 0 0 37.28
17 INT105991 Negative_regulation of IDS 12 0.38 6.31 1.04 30.32
18 INT116728 Negative_regulation of ARSH 9 0.13 9.67 0.27 30.32
19 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 25.00
20 INT275886 Gene_expression of Cm3 25 0.23 4.01 0 21.40
21 INT201239 Gene_expression of FOXM1 9 0.51 4.07 0.19 15.32
22 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
23 INT15913 Negative_regulation of CYP2D6 174 0.59 22.45 70.91 5.00
24 INT50405 Negative_regulation of CYP3A4 238 0.59 53.65 51.51 5.00
25 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
26 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 5.00
27 INT10797 Binding of CYP2D6 86 0.48 15.09 31.16 5.00
28 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
29 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
30 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 5.00
31 INT19944 Negative_regulation of IFNG 39 0.58 22.35 10.91 5.00
32 INT22210 Gene_expression of CYP1A2 45 0.78 4.95 10.66 5.00
33 INT55418 Regulation of CYP2D6 29 0.61 1.83 10.21 5.00
34 INT148703 Gene_expression of NOVA2 73 0.65 18.05 8.3 5.00
35 INT270 Regulation of MAOA 17 0.60 2.58 6.84 5.00
36 INT12333 Regulation of CYP3A 18 0.62 2.25 6.74 5.00
37 INT80419 Gene_expression of Kdm5d 50 0.62 22.49 6.1 5.00
38 INT84965 Gene_expression of MAOA 15 0.75 6.9 6.06 5.00
39 INT203048 Gene_expression of PDCD1 13 0.78 8.5 2.62 5.00
40 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 5.00
41 INT65948 Binding of DNASE1L3 8 0.31 1.38 2.21 5.00
42 INT64378 Gene_expression of DMRT1 9 0.54 1.72 1.71 5.00
43 INT189169 Positive_regulation of MTNR1B 10 0.16 3.71 1.61 5.00
44 INT164156 Positive_regulation of PHLDA2 6 0.42 1.74 1.24 5.00
45 INT60766 Gene_expression of COL4A4 10 0.77 13.46 1.14 5.00
46 INT115845 Positive_regulation of Gene_expression of DNASE1L3 2 0.40 0.58 0.9 5.00
47 INT70933 Regulation of SEPHS1 3 0.37 2.56 0.81 5.00
48 INT243845 Localization of MAOA 4 0.55 1.52 0.77 5.00
49 INT99290 Positive_regulation of STS 16 0.43 6.96 0.75 5.00
50 INT47553 Gene_expression of ARSH 11 0.42 4.93 0.65 5.00
51 INT203749 Binding of FOXM1 10 0.31 6.1 0.64 5.00
52 INT261979 Positive_regulation of PDCD1 4 0.49 6.95 0.61 5.00
53 INT203748 Binding of STS 8 0.41 0.83 0.53 5.00
54 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 5.00
55 INT290601 Positive_regulation of INO80B 1 0.20 1.17 0.24 5.00
56 INT189172 Regulation of MTNR1B 3 0.06 0.43 0.24 5.00
57 INT203750 Positive_regulation of FOXM1 8 0.39 2.72 0.19 5.00
58 INT189175 Localization of MTNR1B 4 0.12 2 0.16 5.00
59 INT310677 Localization of ARSB 1 0.71 5.72 0.14 5.00
60 INT189174 Positive_regulation of Localization of MTNR1B 2 0.09 0.76 0.13 5.00
61 INT203751 Negative_regulation of FOXM1 2 0.20 0.94 0.11 5.00
62 INT290600 Phosphorylation of INO80B 1 0.34 0.87 0.07 5.00
63 INT183086 Regulation of HTL 3 0.24 1.46 0.05 5.00
64 INT310678 Protein_catabolism of ARSH 1 0.06 1.76 0.04 5.00
65 INT310683 Protein_catabolism of ARSB 1 0.73 1.85 0.04 5.00
66 INT310682 Regulation of ARSB 1 0.43 0.98 0.04 5.00
67 INT310679 Positive_regulation of ARSB 1 0.39 2.36 0.04 5.00
68 INT189173 Negative_regulation of MTNR1B 2 0.06 0.3 0 5.00
69 INT316179 Localization of PSG5 1 0.44 0 0 5.00
70 INT316180 Regulation of Localization of MTNR1B 1 0.04 0.07 0 5.00
71 INT316178 Negative_regulation of Localization of MTNR1B 1 0.09 0.31 0 5.00
72 INT282816 Localization of DMRT1 1 0.05 0 0 5.00
73 INT203752 Regulation of FOXM1 1 0.02 0 0 5.00
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