D:Heart Defects

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Disease Term
Synonyms Abnormalities Heart, Abnormality Heart, Atrial Septal Defect, Carotid Intimal Medial Thickness, Congenital Heart Defect, CONGENITAL HEART DEFECTS, Cordis Ectopia, Coronary Spasm, Defect Congenital Heart, Defects Congenital Heart, ECTOPIA CORDIS
Documents 340
Hot Single Events 59
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Heart Defects. They are ordered first by their relevance to Heart Defects and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT214412 CASQ1 Regulation of JUND 1 0.02 0.46 0.24 85.28
2 INT235004 Binding of PKP1 and Dsp 1 0.00 0.14 0 70.16
3 INT335028 Fgf15 Positive_regulation of Fgfr4 1 0.40 0.31 0.25 50.92
4 INT216042 Binding of Rtn4r and Gtf3a 1 0.01 0.41 0.15 39.60
5 INT216043 Binding of Rtn4r and Lingo1 1 0.15 0.82 0.3 36.88
6 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0 36.16
7 INT216041 Binding of Tnfrsf1b and Rtn4r 1 0.10 0.75 0.2 35.92
8 INT216040 Binding of Comt and Prodh 1 0.30 1.71 0.26 34.48
9 INT216039 Binding of Prodh and Zdhhc8 1 0.30 0.85 0.13 34.48
10 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24 32.60
11 INT213207 Negative_regulation of ASAP2 Negative_regulation of PVR 1 0.01 0.45 0.04 31.88
12 INT213206 ASAP2 Negative_regulation of PVR 1 0.01 0.44 0.04 31.48
13 INT235001 Binding of PKP1 and Sergef 1 0.01 0.06 0 30.88
14 INT235021 PKP1 Regulation of CDC42EP5 1 0.00 0.06 0 30.88
15 INT235011 Ctnnd1 Positive_regulation of RAC1 1 0.00 0.07 0 22.12
16 INT234996 Ctnnd1 Positive_regulation of CDC42 1 0.01 0.07 0 22.12
17 INT214411 DNAH8 Regulation of CAPN1 1 0.00 1.01 0.94 21.20
18 INT214408 ATP1A4 Regulation of DNAH8 1 0.04 1.01 0.94 21.20
19 INT214409 ATP1A4 Regulation of CAPN1 1 0.01 1.01 0.93 21.20
20 INT249968 Cxcr4 Positive_regulation of Cxcl12 1 0.17 0.55 0.08 16.64
21 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29 13.72
22 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17 10.64
23 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13 6.72
24 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13 6.72
25 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 6.32
26 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18 6.32
27 INT122660 Binding of CACNA1A and DNAH8 2 0.28 2.68 2.08 5.00
28 INT108727 Binding of ATP1A2 and CACNA1A 2 0.34 1.97 1.37 5.00
29 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7 5.00
30 INT273617 Gene_expression of Slc6a4 Positive_regulation of Pah 1 0.02 0.93 0.38 5.00
31 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26 5.00
32 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26 5.00
33 INT335025 Gm7647 Positive_regulation of Gene_expression of Fgf21 1 0.01 0.29 0.21 5.00
34 INT234992 Car2 Positive_regulation of Jup 1 0.02 0.27 0.2 5.00
35 INT235014 Car2 Positive_regulation of DSP 1 0.06 0.28 0.2 5.00
36 INT249962 Binding of KIT and KITLG 6 0.19 3.69 0.17 5.00
37 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13 5.00
38 INT273616 PVR Positive_regulation of Pah 1 0.10 0.86 0.07 5.00
39 INT201227 C2 Regulation of CEBPZ 2 0.06 1.19 0.07 5.00
40 INT234968 IgG Negative_regulation of Jup 1 0.02 1.09 0.06 5.00
41 INT235006 IgG Positive_regulation of SRC 1 0.01 0.82 0.05 5.00
42 INT335023 Fgf21 Positive_regulation of Gene_expression of Igf1 1 0.49 0.65 0.05 5.00
43 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
44 INT235010 Positive_regulation of Positive_regulation of SRC 1 0.01 0.84 0.05 5.00
45 INT216044 Positive_regulation of Binding of Tnfrsf1b and Rtn4r 1 0.14 0.34 0.05 5.00
46 INT234990 Binding of Cish and Dsp 1 0.01 0.24 0.04 5.00
47 INT235003 Binding of NKS1 and Rdh2 1 0.00 0.18 0.04 5.00
48 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04 5.00
49 INT234986 Binding of Rdh2 and Dsp 1 0.00 0.24 0.04 5.00
50 INT234994 Binding of NKS1 and Dsg3 1 0.00 0.5 0.04 5.00
51 INT235012 Binding of NKS1 and Dsp 1 0.00 0.24 0.04 5.00
52 INT234998 Binding of NKS1 and Cish 1 0.00 0.18 0.04 5.00
53 INT234991 Binding of Dsg3 and Positive_regulation of Pik3r1 1 0.05 0.32 0.03 5.00
54 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03 5.00
55 INT234981 Binding of Dsg3 and Negative_regulation of Gsk3b 1 0.07 0.3 0.03 5.00
56 INT234984 Binding of Dsg3 and Positive_regulation of Akt1 1 0.03 0.32 0.03 5.00
57 INT234978 Binding of Dsg3 and Positive_regulation of Inppl1 1 0.00 0.32 0.03 5.00
58 INT234975 Binding of Dsg3 and Negative_regulation of Gsk3a 1 0.03 0.3 0.03 5.00
59 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
60 INT234995 Binding of CDH16 and Jup 1 0.00 0.27 0 5.00
61 INT234972 IgG Positive_regulation of Gene_expression of Dsg3 1 0.05 0.8 0 5.00
62 INT235002 Negative_regulation of Binding of DSG1 and Dsg3 1 0.13 1.08 0 5.00
63 INT274435 Binding of Zfpm2 and Mir130a 1 0.30 0.26 0 5.00
64 INT335013 Fgf21 Positive_regulation of Localization of Ins1 1 0.06 0.58 0 5.00
65 INT209454 Binding of PSMD1 and PSMD2 1 0.15 0 0 5.00
66 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
67 INT234969 Jup Regulation of Gene_expression of Dsp 1 0.01 0.54 0 5.00
68 INT235007 Binding of DSG1 and Jup 1 0.08 0.36 0 5.00
69 INT235005 Positive_regulation of Binding of DSG1 and Jup 1 0.08 0.36 0 5.00
70 INT234985 Binding of Dsg3 and Pitx3 1 0.00 0.3 0 5.00
71 INT234979 IgG Negative_regulation of Binding of Dsg3 1 0.06 1.59 0 5.00
72 INT209452 Binding of PSMD2 and PSMD3 1 0.07 0.2 0 5.00
73 INT234983 IgG Positive_regulation of Protein_catabolism of Jup 1 0.03 0.61 0 5.00
74 INT274432 Mir130a Regulation of Zfpm2 1 0.22 0.08 0 5.00
75 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
76 INT274431 Mir130a Regulation of Gene_expression of Zfpm2 1 0.50 0.79 0 5.00
77 INT335012 Fgf21 Positive_regulation of Gene_expression of Ins1 1 0.06 0.57 0 5.00
78 INT234970 Binding of Jup and Lat 1 0.01 0 0 5.00
79 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
80 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
81 INT313384 Binding of PDLIM5 and ZMYND10 1 0.04 0.82 0 5.00
82 INT209453 Binding of PSMD1 and PSMD3 1 0.08 0.2 0 5.00
83 INT235019 Binding of DSC1 and DSP 1 0.39 0.07 0 5.00
84 INT235018 Binding of DSP and GOPC 1 0.02 0.19 0 5.00
85 INT234997 Binding of DSG1 and Car2 1 0.03 0.1 0 5.00
86 INT235000 IgG Negative_regulation of DSG1 1 0.04 0.86 0 5.00
87 INT335022 Fgf15 Regulation of Pbx1 1 0.15 0.17 0 5.00
88 INT234987 Binding of Jup and Dsp 1 0.01 0.18 0 5.00
89 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0 5.00
90 INT274433 Binding of Zfpm2 and Uts2r 1 0.08 0.17 0 5.00
91 INT234999 IgG Positive_regulation of Gene_expression of DSG1 1 0.05 0.8 0 5.00
92 INT193147 CRAMP1L Regulation of TSPO 1 0.01 0.27 0 5.00
93 INT235015 Binding of DSP and Dsp 1 0.02 0.25 0 5.00
94 INT274436 Mir130a Regulation of Transcription of Zfpm2 1 0.22 0 0 5.00
95 INT192044 Binding of DSP and Jup 2 0.24 2.39 0 5.00
96 INT235008 Binding of DSG1 and Dsg3 1 0.11 4.82 0 5.00
97 INT234974 Binding of Lat and Dsp 1 0.00 0 0 5.00
98 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0 5.00
99 INT234988 Negative_regulation of Binding of Dsg3 and IgG 1 0.04 0.83 0 5.00
100 INT234989 IgG Positive_regulation of Positive_regulation of Car2 1 0.01 0.98 0 5.00
101 INT234993 Binding of Car2 and Dsp 1 0.00 0 0 5.00
102 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0 5.00
103 INT234966 Phosphorylation of Jup Regulation of Binding of DSP and Jup 1 0.03 0.49 0 5.00
104 INT234982 Binding of Jup and Pkp1 1 0.00 0 0 5.00
105 INT234967 Binding of Dsg3 and IgG 1 0.03 0.83 0 5.00
106 INT279890 Nipbl Regulation of Gene_expression of PCDHB@ 1 0.07 0.1 0 5.00
107 INT235016 IgG Negative_regulation of Binding of DSG1 1 0.04 2.89 0 5.00
108 INT317900 Binding of NCAPH2 and MCPH1 1 0.02 0.53 0 5.00
109 INT235009 Binding of DSG1 and Cdh1 1 0.02 0.87 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Heart Defects. They are ordered first by their pain relevance and then by number of times they were reported in Heart Defects. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT334157 Binding of DTNA 1 0.10 9.81 0.86 100.00
2 INT263073 Gene_expression of TAPVR1 6 0.58 4.66 2.61 100.00
3 INT334158 Positive_regulation of DTNA 1 0.10 1.85 0.12 100.00
4 INT47010 Negative_regulation of Gusb 6 0.43 4.16 1.2 100.00
5 INT228409 Localization of DSP 5 0.73 2.39 0.11 99.82
6 INT193156 Gene_expression of CRAMP1L 17 0.42 10.96 0.18 99.66
7 INT234867 Localization of Jup 1 0.24 2.84 0.03 99.56
8 INT234914 Localization of Pkp2 1 0.06 1.47 0 99.30
9 INT234883 Regulation of Pkp2 1 0.02 1.2 0 99.16
10 INT234861 Binding of Pkp2 1 0.03 1.2 0 99.16
11 INT274417 Negative_regulation of Zfpm2 1 0.43 6.99 0 99.08
12 INT234937 Localization of DSG1 5 0.66 4.14 0 99.00
13 INT334975 Gene_expression of Fgf15 1 0.74 7.12 2.02 98.88
14 INT234856 Localization of Dsc2 1 0.21 1.28 0 98.80
15 INT234923 Binding of Dsc2 2 0.34 1.8 0 98.44
16 INT234873 Regulation of Dsc2 1 0.08 1.2 0 98.44
17 INT213213 Protein_catabolism of PAH 1 0.76 1.5 0.07 98.36
18 INT234950 Binding of DSG1 29 0.36 23.67 0.69 98.08
19 INT234940 Regulation of DSG1 2 0.21 2.29 0 98.08
20 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77 98.04
21 INT111739 Negative_regulation of Npy 15 0.43 4.9 4.65 98.04
22 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84 98.04
23 INT279847 Negative_regulation of Cebpb 2 0.28 1.82 0.44 98.04
24 INT279843 Negative_regulation of Ebf1 1 0.37 0.6 0 98.04
25 INT274421 Gene_expression of Mir130a 1 0.55 15.48 0 97.96
26 INT274407 Positive_regulation of Gene_expression of Mir130a 1 0.49 5.1 0 97.96
27 INT9110 Binding of PAH 32 0.41 42.1 3.1 97.96
28 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 97.48
29 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 97.48
30 INT10706 Regulation of Il6 150 0.62 93.23 62.34 97.20
31 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7 96.64
32 INT213221 Negative_regulation of ASAP2 1 0.01 5.83 0.46 96.44
33 INT185722 Positive_regulation of GATA4 2 0.50 1.09 0.39 95.96
34 INT234954 Negative_regulation of DSG1 22 0.42 19.5 0.62 95.92
35 INT193157 Regulation of Gene_expression of CRAMP1L 1 0.12 1.35 0 95.48
36 INT140647 Gene_expression of DSG1 45 0.75 27.95 1.33 95.44
37 INT193154 Regulation of CRAMP1L 5 0.28 3.04 0.34 95.12
38 INT164682 Gene_expression of PKP1 3 0.78 3.04 0.17 95.04
39 INT279846 Gene_expression of Nipbl 1 0.68 11.1 0.56 95.00
40 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.40
41 INT45342 Binding of AVSD1 6 0.31 7.23 0.27 94.08
42 INT330511 Gene_expression of Bmpr1a 1 0.54 1.9 0 94.00
43 INT267892 Gene_expression of Prkag2 3 0.62 3.59 0 93.28
44 INT279830 Regulation of Transcription of Nipbl 1 0.39 0.62 0 93.20
45 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 93.04
46 INT279869 Negative_regulation of Nipbl 1 0.43 4.3 0.03 92.56
47 INT279871 Negative_regulation of Transcription of Nipbl 1 0.43 1.22 0 92.56
48 INT279841 Transcription of Nipbl 1 0.63 1.21 0 92.08
49 INT274405 Gene_expression of Zfpm2 1 0.77 6.51 0 90.56
50 INT300167 Binding of FBXL15 2 0.39 5 0.19 90.32
51 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 85.24
52 INT20462 Binding of ESR1 210 0.44 102.7 26.34 85.04
53 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 84.84
54 INT7894 Negative_regulation of Vip 59 0.59 11.76 27.36 83.36
55 INT234892 Gene_expression of Pkp2 1 0.06 0.41 0 82.96
56 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 81.80
57 INT127460 Positive_regulation of Gene_expression of PAH 5 0.43 4.3 0.5 81.80
58 INT279856 Regulation of Pcdhb1 1 0.42 0.89 0 81.40
59 INT279882 Regulation of PCDHB@ 1 0.06 0.89 0 81.40
60 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 79.92
61 INT90909 Negative_regulation of Gene_expression of NOS1 44 0.55 23.83 12.47 79.92
62 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 79.84
63 INT244771 Gene_expression of Satb2 4 0.68 1.27 0.03 78.64
64 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 78.40
65 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 78.36
66 INT279850 Gene_expression of Trps1 1 0.38 0.47 0 78.08
67 INT120165 Binding of NTM 2 0.47 2.23 0.29 77.84
68 INT317915 Binding of SNX19 1 0.36 2.04 0.2 77.84
69 INT51897 Binding of OPCML 8 0.43 5.59 1.11 77.84
70 INT317919 Binding of VPS26B 1 0.23 0.93 0.1 77.84
71 INT317908 Binding of NCAPD3 1 0.32 0.91 0.1 77.84
72 INT317904 Binding of THYN1 1 0.32 0.96 0.1 77.84
73 INT279858 Gene_expression of Tcof1 1 0.40 0.47 0 77.80
74 INT105344 Gene_expression of Cited2 5 0.78 3.65 0.76 77.52
75 INT274414 Regulation of Zfpm2 1 0.61 0.59 0 77.28
76 INT111009 Negative_regulation of Tcm 5 0.45 1.73 0.57 77.12
77 INT19541 Gene_expression of Ptgir 22 0.65 15.42 5.39 75.52
78 INT279842 Regulation of Rec8 1 0.01 0.6 0 74.96
79 INT216025 Localization of Rtn4r 3 0.75 2.65 0.42 73.84
80 INT244343 Localization of NTM 16 0.73 14.26 0.26 72.48
81 INT201234 Positive_regulation of Regulation of CHM 1 0.22 0.15 0 72.12
82 INT21660 Regulation of CHM 14 0.61 8.51 0.93 71.72
83 INT274426 Regulation of Binding of Mir130a 1 0.32 0.41 0 71.44
84 INT176205 Gene_expression of Cyp7a1 8 0.69 2.5 2.45 71.28
85 INT262093 Positive_regulation of Gene_expression of Cyp7a1 2 0.44 0.81 0.55 71.28
86 INT89582 Binding of PKP1 3 0.36 0.85 0 70.16
87 INT279853 Negative_regulation of Gene_expression of Nipbl 1 0.51 2.37 0.19 70.00
88 INT274411 Positive_regulation of Zfpm2 1 0.46 0.53 0 70.00
89 INT234865 Binding of Dsp 1 0.02 2.48 0.25 69.24
90 INT274410 Binding of Mir130a 1 0.27 0.66 0 69.20
91 INT36978 Localization of Pah 9 0.73 7.43 0.82 68.00
92 INT317914 Localization of NCAPD3 1 0.65 0.88 0.1 67.36
93 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 67.28
94 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 67.16
95 INT12157 Positive_regulation of SELL 16 0.67 14.54 5.74 65.84
96 INT234898 Negative_regulation of Gene_expression of Dsp 1 0.02 3.92 0.03 65.32
97 INT234864 Gene_expression of Dsp 30 0.47 17.72 0.37 64.96
98 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 64.60
99 INT107942 Positive_regulation of C5 9 0.50 6.86 1.19 64.56
100 INT334987 Positive_regulation of Fgf15 1 0.66 2.32 0.31 63.76
101 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 63.04
102 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 63.04
103 INT317911 Localization of VPS26B 1 0.47 0.88 0.1 62.64
104 INT317907 Gene_expression of DLGAP2 1 0.63 0.85 0 61.00
105 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 60.00
106 INT234956 Localization of PKP1 1 0.14 0.2 0 59.20
107 INT81155 Localization of CDCP1 5 0.08 4.49 1.4 58.88
108 INT317920 Localization of SNX19 1 0.73 1.88 0.2 58.40
109 INT51895 Localization of OPCML 6 0.68 3.43 0.54 58.40
110 INT317910 Localization of THYN1 1 0.65 0.88 0.1 58.40
111 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 57.80
112 INT274408 Binding of Zfpm2 1 0.37 0.77 0 57.64
113 INT70615 Binding of TXNRD1 25 0.36 12.15 1.27 56.24
114 INT274420 Positive_regulation of Gene_expression of Zfpm2 1 0.49 0.51 0 56.16
115 INT4137 Positive_regulation of C3 73 0.69 48.57 12.63 55.84
116 INT52349 Gene_expression of CHM 7 0.77 17.33 0.28 55.36
117 INT303541 Gene_expression of Fgfr4 2 0.62 0.72 0.43 54.96
118 INT133080 Gene_expression of GATA3 15 0.61 5.64 2.89 52.48
119 INT9205 Binding of DSP 12 0.44 9.9 1.21 52.48
120 INT243481 Gene_expression of GATA2 3 0.50 3.34 0.62 52.48
121 INT251745 Gene_expression of GATA1 2 0.58 0.96 0.51 52.48
122 INT170900 Regulation of Positive_regulation of Gopc 10 0.20 3.44 1.24 49.72
123 INT334990 Regulation of Positive_regulation of Fgfr4 1 0.36 0.25 0.25 49.72
124 INT16854 Gene_expression of Uts2r 17 0.26 3.1 1.31 49.68
125 INT274423 Positive_regulation of Gene_expression of Uts2r 3 0.09 0.58 0 49.68
126 INT146197 Positive_regulation of Rhoa 60 0.68 34.12 12.02 48.24
127 INT146192 Positive_regulation of Positive_regulation of Rhoa 8 0.60 8.15 2.17 48.24
128 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 47.24
129 INT334992 Positive_regulation of Fgfr4 1 0.40 0.24 0.25 47.24
130 INT213217 Negative_regulation of Binding of PAH 2 0.32 2.03 0.19 47.24
131 INT129971 Regulation of PVR 5 0.60 3.96 0.97 47.16
132 INT213220 Regulation of ASAP2 1 0.01 1.73 0.15 47.16
133 INT234958 Gene_expression of DSC3 1 0.10 2.75 0.11 44.40
134 INT234857 Gene_expression of Dsg3 42 0.78 27.75 0.14 43.92
135 INT216030 Positive_regulation of Rtn4r 5 0.50 2.78 0.49 43.68
136 INT234862 Gene_expression of Dsc2 8 0.70 3.29 0 43.12
137 INT274427 Negative_regulation of Gene_expression of Mir130a 1 0.30 0.14 0 42.88
138 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 42.80
139 INT234880 Regulation of Gene_expression of Dsp 1 0.02 4.75 0.03 40.72
140 INT185724 Regulation of GATA4 2 0.45 1.6 1.33 39.64
141 INT335005 Regulation of Gene_expression of Fgf15 1 0.58 0.8 0.66 39.64
142 INT273611 Positive_regulation of Localization of Pah 1 0.40 0.75 0.24 38.96
143 INT274413 Regulation of Mir130a 1 0.32 0.21 0 38.36
144 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 38.20
145 INT251744 Binding of GATA4 1 0.36 1.55 0.96 38.12
146 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 37.92
147 INT159661 Binding of AHA 1 0.40 0.61 0 37.84
148 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 37.80
149 INT15819 Negative_regulation of RBP1 4 0.56 2.58 0.83 37.44
150 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 37.08
151 INT287496 Regulation of lla 2 0.03 0.46 0.21 36.64
152 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 36.16
153 INT274404 Binding of Gata4 2 0.16 0.89 0 36.16
154 INT101120 Gene_expression of Comt 63 0.77 34.75 26.13 35.40
155 INT216033 Gene_expression of Prodh 1 0.57 1.09 0.13 35.40
156 INT216028 Gene_expression of Zdhhc8 1 0.58 1.09 0.13 35.40
157 INT216037 Binding of Prodh 1 0.32 0.85 0.13 34.48
158 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 34.24
159 INT216021 Binding of Zdhhc8 1 0.32 0.85 0.13 34.16
160 INT335010 Positive_regulation of Gene_expression of Fgf15 1 0.48 0.2 0.24 34.08
161 INT18025 Binding of Pah 32 0.45 30.72 7.93 33.92
162 INT150825 Binding of Comt 13 0.42 6.65 6.42 33.72
163 INT64096 Negative_regulation of AHR 5 0.37 1.2 0.58 33.12
164 INT334977 Regulation of Gene_expression of Cyp7a1 2 0.40 0.43 0.94 31.76
165 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 29.60
166 INT199086 Binding of Sergef 2 0.08 0.28 0 27.40
167 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68 27.24
168 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71 27.24
169 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 27.12
170 INT279862 Binding of Nipbl 1 0.36 1.22 0.04 26.72
171 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 26.28
172 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 25.68
173 INT213214 Positive_regulation of ASAP2 1 0.01 4.59 0.31 25.68
174 INT234912 Protein_catabolism of Dsp 1 0.05 2.04 0 25.52
175 INT29651 Regulation of Pah 11 0.37 9.95 2.79 24.80
176 INT206463 Positive_regulation of Positive_regulation of ASAP1 4 0.41 1.28 0.07 24.64
177 INT314554 Gene_expression of Fgf21 3 0.74 7.97 2.48 24.44
178 INT332832 Positive_regulation of Gene_expression of Fgf21 2 0.66 3.18 1.29 24.44
179 INT135337 Gene_expression of PTPRN2 2 0.72 0.82 0 23.52
180 INT234922 Negative_regulation of Dsp 1 0.02 6.01 0.08 22.72
181 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 22.40
182 INT334978 Binding of Nucb2 2 0.07 0.26 0.22 21.60
183 INT131472 Regulation of Pde5a 11 0.42 6.95 3.06 21.44
184 INT317903 Gene_expression of NCAPG2 1 0.64 1.56 0 21.28
185 INT21545 Regulation of DNAH8 22 0.59 8.67 6.48 21.20
186 INT214417 Regulation of ATP1A4 1 0.38 1.01 0.93 21.20
187 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 20.00
188 INT97955 Positive_regulation of CDC42 8 0.49 2.47 1.19 20.00
189 INT234903 Gene_expression of Jup 1 0.23 7.1 0.2 20.00
190 INT234896 Negative_regulation of Gene_expression of Jup 1 0.13 0.54 0 20.00
191 INT139281 Gene_expression of VIPR2 3 0.74 0.88 0.2 19.88
192 INT273614 Regulation of PVR 1 0.17 0.84 0.14 19.68
193 INT257299 Binding of Pde5a 14 0.27 4.31 2.45 19.44
194 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 19.20
195 INT201233 Localization of CEBPZ 4 0.62 0.82 0.77 18.08
196 INT317905 Gene_expression of ESYT2 1 0.64 0.76 0 17.88
197 INT234859 Negative_regulation of Positive_regulation of Dsp 1 0.02 0.85 0 16.72
198 INT136309 Positive_regulation of Cxcl12 24 0.62 12.45 5.58 16.64
199 INT234855 Localization of Dsp 1 0.03 1.65 0.22 16.20
200 INT317906 Gene_expression of WDR60 1 0.71 0.74 0 15.96
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