D:Heart Rate Under Development

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Disease Term
Synonyms ASYSTOLE, Atrial Arrest, Atrial Arrests, Atrial Extrasystoles, Atrial Tachycardia, Bigeminal Extrasystole, BIGEMINY, BLOCK HEART, BRADYARRHYTHMIA, Bradycardia, BRADYCARDIA HEART RATE LESS THAN 50 BPM
Documents 15131
Hot Single Events 200
Hot Interactions 108

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Heart Rate Under Development. They are ordered first by their relevance to Heart Rate Under Development and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT28562 SOD1 Negative_regulation of Pacs1 1 0.03 2.63 0.19 100.00
2 INT252575 Rpe Negative_regulation of SOD1 1 0.03 2.39 0.14 100.00
3 INT252573 Rpe Negative_regulation of Gpx1 1 0.07 2.34 0.13 100.00
4 INT252571 Rpe Positive_regulation of Positive_regulation of Sdcbp 1 0.04 2.27 0.13 100.00
5 INT216709 Binding of SELP and PSMG1 3 0.08 1.48 0.37 100.00
6 INT332735 Binding of Shbg and Hr 1 0.06 0.6 0 100.00
7 INT41977 Binding of Htr1a and Dync1i2 1 0.02 0.54 0.18 100.00
8 INT41978 Binding of Agt and Htr1a 1 0.41 0.54 0.18 100.00
9 INT194100 Binding of MKLN1 and HELT 1 0.01 1.23 0.21 100.00
10 INT329587 Binding of PTX3 and HEY1 1 0.00 2.03 0.5 100.00
11 INT252572 Rpe Positive_regulation of Sdcbp 1 0.04 1.12 0.09 100.00
12 INT150350 Oprk1 Regulation of Pat 1 0.22 0.38 0.81 100.00
13 INT150348 Oprd1 Regulation of Pat 1 0.01 0.38 0.81 100.00
14 INT270084 Binding of PLEK and PSMG1 1 0.09 0.26 0 100.00
15 INT216707 Positive_regulation of Binding of SELP and PSMG1 1 0.10 0.36 0.09 100.00
16 INT160721 ecs Positive_regulation of MPST 1 0.11 0.54 0.11 100.00
17 INT216712 Binding of ITGA2B and PSMG1 1 0.09 0.18 0.05 100.00
18 INT216706 Positive_regulation of Binding of ITGA2B and PSMG1 1 0.12 0.18 0.05 100.00
19 INT191220 Cotl1 Positive_regulation of Edn1 1 0.19 0.69 0 99.96
20 INT216708 Binding of ITGA2B and SELP 1 0.35 0.36 0.09 99.92
21 INT216710 Positive_regulation of Binding of ITGA2B and SELP 1 0.48 0.36 0.09 99.92
22 INT217620 Dep1 Positive_regulation of Gene_expression of Tlr4 1 0.20 0.4 0.12 99.92
23 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49 99.78
24 INT325284 Binding of COMP and MCL1 1 0.01 1.69 0 99.56
25 INT303878 Fig4 Negative_regulation of Nav1 1 0.11 0.4 0.05 99.52
26 INT87723 Binding of ras and Thim 1 0.00 1.86 0.55 99.44
27 INT262994 Binding of CRP and HSD11B1 1 0.15 3.02 0.03 99.32
28 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 99.32
29 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19 99.24
30 INT351281 AP1M2 Regulation of NCOR2 1 0.00 0.85 1.9 98.84
31 INT191214 Cotl1 Positive_regulation of Prkcg 1 0.10 1.35 0.04 98.64
32 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07 98.36
33 INT71519 Edn1 Positive_regulation of Gene_expression of Adarb1 1 0.02 0.48 0.31 98.32
34 INT329317 ACE Regulation of Positive_regulation of KNG1 1 0.02 1.05 0.12 98.28
35 INT329325 ACE Regulation of Negative_regulation of Agtr2 1 0.01 0.93 0.12 98.28
36 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 97.92
37 INT345297 Binding of NAGLU and Lcn2 1 0.01 1.24 0.07 97.84
38 INT265264 Binding of NA and SCN5A 1 0.03 0.55 0 97.76
39 INT303896 Ina Regulation of NAA50 1 0.14 0.24 0 97.50
40 INT303895 Nav1 Regulation of NAA50 1 0.11 0.24 0 97.34
41 INT222690 TNF Positive_regulation of Gene_expression of NPEPPS 1 0.01 1.03 0.3 97.28
42 INT345292 Binding of Lcn2 and Havcr1 1 0.00 1.17 0.07 97.20
43 INT240131 Binding of Crp and Nppb 7 0.07 11.53 2.12 96.80
44 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 96.72
45 INT194722 Negative_regulation of MAPK1 Negative_regulation of Gene_expression of CRP 1 0.09 1.49 0.41 96.36
46 INT291967 INA Positive_regulation of NA 1 0.00 0.98 0.14 95.72
47 INT196303 Binding of SCN5A and ACCS 1 0.00 1.43 0.18 95.52
48 INT108409 AGT Positive_regulation of AGTR2 2 0.31 1.49 1.11 94.96
49 INT194705 Negative_regulation of MAPK1 Negative_regulation of Positive_regulation of IK 1 0.00 1.46 0.41 94.76
50 INT329324 KNG1 Positive_regulation of Localization of ecs 1 0.00 1.16 0.17 94.44
51 INT239396 Atp7b Negative_regulation of Gene_expression of Icam1 1 0.07 1.69 0.26 94.08
52 INT142332 Binding of SERPINH1 and TNNI3 1 0.03 1.05 0.17 94.00
53 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 94.00
54 INT191216 Binding of Edn1 and Cotl1 1 0.14 0.63 0.05 93.80
55 INT142171 Positive_regulation of Adarb1 Positive_regulation of Apcs 1 0.01 0.19 0.43 93.76
56 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26 93.68
57 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0 93.64
58 INT194821 MAPK1 Regulation of Hand2 1 0.03 1.27 0.28 93.56
59 INT80718 Trpv3 Negative_regulation of Chn1 1 0.01 0.7 0.92 93.08
60 INT26367 POMC Regulation of Localization of NPPA 1 0.28 0.29 0.16 93.04
61 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 92.52
62 INT328744 TNF Regulation of Positive_regulation of Mapk14 1 0.02 0.81 0.55 92.16
63 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 91.88
64 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 91.88
65 INT194101 MKLN1 Positive_regulation of Binding of SCD 1 0.08 1.16 0 90.76
66 INT194102 MKLN1 Regulation of Positive_regulation of SCD 1 0.07 1.13 0 90.76
67 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 90.72
68 INT325283 Negative_regulation of MCL1 Positive_regulation of Gene_expression of ADIPOQ 1 0.14 1.53 0 90.32
69 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 90.12
70 INT165583 Binding of Bdnf and Ngf 3 0.33 0.81 0.69 89.44
71 INT191241 SST Regulation of SAE1 1 0.05 0.89 0.18 88.88
72 INT86448 Binding of Cnr1 and Lipg 1 0.28 0.64 0.06 88.64
73 INT110176 Nts Regulation of Negative_regulation of Agtr1a 1 0.24 0.09 0.12 88.24
74 INT39594 TPO Positive_regulation of CALR 1 0.30 0.91 0.32 88.04
75 INT288910 REN Regulation of Gene_expression of AGT 1 0.40 1.34 0 87.48
76 INT270731 Binding of AGTR1 and ACE 1 0.02 0.67 0.09 87.28
77 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28 87.04
78 INT208459 Galns Negative_regulation of Negative_regulation of BCAN 1 0.01 0.44 0.13 86.84
79 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 86.64
80 INT345290 AGT Positive_regulation of NOX1 1 0.00 1.11 0.12 86.64
81 INT286432 Binding of ANTXR2 and Gtf3a 1 0.00 3.56 0.1 86.60
82 INT28006 NPC1 Negative_regulation of Positive_regulation of Rps6ka1 1 0.01 0.37 0.33 86.44
83 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 86.00
84 INT189396 MBD4 Regulation of C11orf2 1 0.05 0.66 0 85.64
85 INT302908 Agtr2 Positive_regulation of Gene_expression of Agt 1 0.00 0.22 0.03 85.60
86 INT230786 Binding of AGT and ACE 4 0.15 2.53 0.34 85.44
87 INT162875 Binding of Npvf and Qrfpr 1 0.35 0.49 0.91 85.32
88 INT222691 Negative_regulation of Binding of FLNA and TNF 1 0.14 1.92 0.54 84.80
89 INT222692 Binding of FLNA and TNF 1 0.12 1.92 0.53 84.80
90 INT122749 Cyp3a23/3a1 Positive_regulation of Phosphorylation of Akt1 1 0.07 0.24 0.41 84.76
91 INT256209 AVP Regulation of PVR 1 0.06 0.99 0 84.64
92 INT61587 Agt Negative_regulation of REN 1 0.00 0.42 0.91 84.48
93 INT259703 Binding of MYBPC3 and HELT 1 0.04 1.64 0 84.40
94 INT229362 Negative_regulation of Agtr1a Positive_regulation of Positive_regulation of Agtr2 1 0.05 1 0 84.28
95 INT196639 Negative_regulation of NA Negative_regulation of Transcription of CFTR 1 0.02 0.63 0.03 84.20
96 INT252425 Positive_regulation of AR Positive_regulation of Gene_expression of CXCL10 1 0.00 0.9 0.44 83.96
97 INT177673 Avp Positive_regulation of Vmn1r51 1 0.04 0.53 0 83.32
98 INT28005 NPC1 Negative_regulation of Rps6ka1 1 0.01 0.45 0.32 82.28
99 INT197190 Positive_regulation of Tlr4 Positive_regulation of Vwf 1 0.33 0.31 0.08 81.92
100 INT247820 Gjc1 Regulation of Gja5 1 0.08 1.24 0 81.84
101 INT30706 Nppa Positive_regulation of Localization of AVP 1 0.78 0.45 0.3 81.64
102 INT30705 Nppa Negative_regulation of Localization of AVP 1 0.48 0.22 0.15 81.64
103 INT334131 Acsm3 Positive_regulation of Mip 1 0.13 3.12 1.48 80.64
104 INT353489 Negative_regulation of Aldh2 Negative_regulation of Prkag1 1 0.00 0.84 0.07 80.56
105 INT254119 Binding of Bcl2a1a and Tlr4 1 0.01 1.34 0.49 80.36
106 INT238472 Binding of AVP and POR 1 0.02 0.85 0.09 80.24
107 INT197191 Tlr4 Positive_regulation of Vwf 1 0.33 0.3 0.08 80.16
108 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 80.04
109 INT47342 Penk Regulation of Fabp6 1 0.01 0.39 0.95 79.60
110 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45 79.32
111 INT311046 Binding of CSF2 and IL33 1 0.00 1.86 0.26 78.00
112 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 77.12
113 INT325767 Negative_regulation of Omd Positive_regulation of Ddc 1 0.01 0.38 0.25 76.56
114 INT25491 TFPI Regulation of Localization of ENG 1 0.27 0.31 0.06 76.52
115 INT325285 COMP Positive_regulation of UBR5 1 0.00 2.9 0 76.40
116 INT194713 MAPK1 Regulation of Gene_expression of TNF 1 0.10 1.66 0.38 76.40
117 INT281314 Positive_regulation of Stx2 Positive_regulation of Gene_expression of Itgam 1 0.08 0.21 0 76.08
118 INT264988 Binding of CYP2C19 and CYP3A4 1 0.18 0.72 1.09 75.72
119 INT264987 Binding of CYP2C9 and CYP3A4 1 0.19 0.71 1.08 75.36
120 INT84622 Binding of RERE and KAL1 1 0.00 1.18 0.07 75.00
121 INT308648 Binding of sps and Gopc 1 0.01 2.71 0 74.64
122 INT66504 Binding of Agt and Agtr1a 8 0.39 3.78 1.78 74.60
123 INT184887 MCRS1 Positive_regulation of ALOX5 1 0.11 0.64 0 73.92
124 INT247271 Tlr4 Negative_regulation of SLC43A3 1 0.00 0.34 0.19 73.44
125 INT254125 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Il6 1 0.00 1.23 0.5 73.12
126 INT254124 Binding of Bcl2a1a and Tlr4 Positive_regulation of Localization of Tbxa2r 1 0.00 0.62 0.25 73.12
127 INT65036 Fgf1 Regulation of Anxa5 1 0.01 0.35 0 72.56
128 INT65035 Fgf1 Regulation of F2 1 0.07 0.34 0 72.56
129 INT174892 Binding of ADRB3 and ENPP3 1 0.04 0.4 0.14 72.56
130 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04 72.44
131 INT210933 Tlr4 Regulation of Il6 1 0.19 0.33 0.18 71.52
132 INT247270 Tlr4 Negative_regulation of Cebpz 1 0.04 0.33 0.19 71.36
133 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06 71.08
134 INT66535 Binding of Pnoc and Oprl1 43 0.54 5.93 32.4 70.56
135 INT70270 Binding of ADRA2B and Pnoc 2 0.02 0.15 1.08 70.08
136 INT207681 Chrnb4 Positive_regulation of Scn2b 1 0.02 0.32 0.1 69.92
137 INT192044 Binding of DSP and Jup 2 0.24 2.39 0 69.80
138 INT192048 Binding of DSP and Ryr2 1 0.24 1.1 0 69.80
139 INT192042 Binding of Jup and Ryr2 1 0.17 1.09 0 69.80
140 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 69.56
141 INT334132 Acsm3 Positive_regulation of Gene_expression of Cxcl2 1 0.13 2.26 0.83 69.32
142 INT244320 Tlr4 Positive_regulation of Aliq1 3 0.04 4.51 0.64 69.20
143 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 68.44
144 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68 68.16
145 INT207683 Chrnb4 Positive_regulation of Htr3b 1 0.26 0.31 0.1 67.76
146 INT136245 Gucy1a2 Positive_regulation of Nppa 1 0.06 0.22 0.27 67.04
147 INT207684 Chrnb4 Positive_regulation of Htr3a 1 0.22 0.3 0.1 66.56
148 INT126227 Hsp90aa1 Positive_regulation of Nos1 1 0.03 0.73 0.25 66.40
149 INT200213 PAH Positive_regulation of SDHD 1 0.21 2.43 0.1 65.64
150 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 64.48
151 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 64.48
152 INT326090 Binding of Erbb2 and Mmp2 1 0.09 1.39 0.31 63.60
153 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 63.52
154 INT250024 Positive_regulation of Ros1 Positive_regulation of Gtf3a 1 0.00 1.26 0.08 63.44
155 INT250023 Positive_regulation of Ros1 Positive_regulation of Nfkb1 1 0.04 1.26 0.08 63.44
156 INT334127 Acsm3 Positive_regulation of Vcam1 1 0.24 1.61 0.66 63.36
157 INT136246 Gucy1a2 Negative_regulation of Nppa 1 0.05 0.22 0.26 62.80
158 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22 62.40
159 INT334133 Acsm3 Positive_regulation of Icam1 1 0.23 1.61 0.66 62.40
160 INT207682 Chrnb4 Positive_regulation of Hcn4 1 0.35 0.29 0.1 62.32
161 INT334128 Acsm3 Positive_regulation of Sele 1 0.16 1.6 0.66 61.76
162 INT250777 Binding of Cxcl10 and Cxcr1 1 0.14 3.1 1.04 61.44
163 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 61.04
164 INT122758 Positive_regulation of Helt Positive_regulation of Akt1 1 0.00 0.2 0.35 60.88
165 INT122756 Helt Positive_regulation of Akt1 1 0.00 0.2 0.35 60.88
166 INT250796 Tlr4 Positive_regulation of Parp1 1 0.14 1 0.03 60.76
167 INT122757 Helt Positive_regulation of Trib3 1 0.00 0.2 0.35 60.72
168 INT192046 Negative_regulation of Binding of RYR2 and Cbx5 1 0.01 1.12 0 60.72
169 INT192049 Negative_regulation of Binding of RYR2 and Cbx1 1 0.01 1.12 0 60.72
170 INT192047 Binding of RYR2 and Cbx1 1 0.01 1.12 0 60.72
171 INT192043 Binding of RYR2 and Cbx5 1 0.01 1.12 0 60.72
172 INT241774 Binding of AVPR1A and TRGV9 1 0.02 0.48 0.09 60.48
173 INT122755 Helt Positive_regulation of Pik3cb 1 0.00 0.19 0.35 60.12
174 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5 59.88
175 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5 59.88
176 INT182775 Binding of PTH and ROS1 1 0.04 1.73 0.04 59.76
177 INT279242 Negative_regulation of Binding of GLA and SH3GL3 1 0.08 1.22 0 59.76
178 INT273291 Atp2a2 Regulation of Car2 1 0.10 0.31 0 59.68
179 INT203009 Binding of Cpb1 and Dob2 1 0.02 0.77 0 59.48
180 INT172513 ECT Negative_regulation of Mir343 1 0.02 0.24 0.47 59.24
181 INT273286 Tlx2 Regulation of Car2 1 0.06 0.31 0 59.20
182 INT279240 Binding of GLA and SH3GL3 1 0.07 1.21 0 58.88
183 INT182816 EEF1A2 Negative_regulation of CRP 1 0.28 1.84 0.21 58.76
184 INT193014 VHL Regulation of EPAS1 1 0.20 0.92 0 58.72
185 INT148061 Binding of Tacr1 and B4galt4 1 0.01 0.06 0.77 58.64
186 INT148062 Binding of Tacr1 and St3gal3 1 0.01 0.06 0.77 58.64
187 INT265830 KNG1 Positive_regulation of Localization of BGN 1 0.02 0.33 0.27 57.96
188 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 57.60
189 INT246683 exf Regulation of Gopc 1 0.01 0.2 0.14 57.28
190 INT345288 AGT Positive_regulation of Localization of CCL2 1 0.01 1.5 0.43 56.84
191 INT345291 AGT Positive_regulation of CCL2 1 0.01 1.39 0.43 56.84
192 INT335840 Binding of GAST and Sult1e1 1 0.03 1.15 0.12 56.32
193 INT236241 Binding of Birc5 and Ifna 1 0.05 0.31 0 56.16
194 INT326097 WAS Regulation of Gopc 1 0.01 0.55 0.16 55.92
195 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 54.08
196 INT327448 Binding of REN and PPAP2B 1 0.01 0.26 0 54.00
197 INT180246 Binding of Tbca and Uchl1 1 0.00 0.47 0.27 53.36
198 INT180245 Binding of Plp1 and Uchl1 1 0.03 0.47 0.27 53.36
199 INT57107 Binding of Msh2 and Nts 1 0.22 0.22 0 52.28
200 INT265831 BGN Positive_regulation of ADCY1 1 0.01 0.41 0.27 52.24

Single Events

The table below shows the top 200 pain related interactions that have been reported for Heart Rate Under Development. They are ordered first by their pain relevance and then by number of times they were reported in Heart Rate Under Development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT112561 Binding of PSMG1 21 0.34 5.89 0.67 100.00
2 INT178918 Negative_regulation of PNC 1 0.17 4.22 0.38 100.00
3 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
4 INT112563 Gene_expression of PSMG1 3 0.55 3.82 0.32 100.00
5 INT149710 Gene_expression of Pvr 10 0.46 8.92 0 100.00
6 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 100.00
7 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 100.00
8 INT17037 Negative_regulation of Hr 11 0.22 11.81 2.46 100.00
9 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 100.00
10 INT2124 Positive_regulation of Pat 4 0.41 3.25 1.44 100.00
11 INT2897 Positive_regulation of Thra 20 0.45 5.17 3.01 100.00
12 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 100.00
13 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 100.00
14 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
15 INT2660 Negative_regulation of Fabp6 58 0.49 33.74 18.27 100.00
16 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 100.00
17 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
18 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
19 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
20 INT65076 Positive_regulation of SLC5A6 1 0.41 3.28 0.4 100.00
21 INT4199 Binding of Agt 76 0.48 21.06 12.66 100.00
22 INT49 Negative_regulation of Ren 129 0.59 37.48 35.62 100.00
23 INT109925 Gene_expression of RPE 11 0.65 12.46 0.68 100.00
24 INT70970 Binding of COPD 144 0.42 180.34 18.29 100.00
25 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 100.00
26 INT148384 Positive_regulation of HEY1 19 0.43 29.76 5.89 100.00
27 INT60053 Regulation of Hibch 1 0.06 1.98 1.65 100.00
28 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 100.00
29 INT112560 Positive_regulation of Binding of PSMG1 5 0.49 1.27 0 100.00
30 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 100.00
31 INT36962 Positive_regulation of vs 9 0.28 5.57 1.92 100.00
32 INT300725 Gene_expression of Pat 2 0.24 1.49 0.28 100.00
33 INT178920 Gene_expression of PnC 4 0.23 1.9 0.38 100.00
34 INT9856 Binding of Pat 5 0.37 1.48 2.05 100.00
35 INT1158 Regulation of Agt 106 0.61 29.4 30.29 100.00
36 INT149764 Negative_regulation of Rpe 3 0.49 2.07 0.16 100.00
37 INT161027 Negative_regulation of RPE 7 0.37 4.34 0.38 100.00
38 INT270091 Positive_regulation of Gene_expression of PSMG1 1 0.11 0.99 0 100.00
39 INT178919 Positive_regulation of PNC 1 0.18 0.99 0.05 100.00
40 INT45209 Positive_regulation of PLA2G2A 37 0.69 33.21 9.02 100.00
41 INT9973 Binding of MMVP1 14 0.48 22.66 1.79 100.00
42 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 100.00
43 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
44 INT11673 Positive_regulation of ECT 43 0.59 13.93 11.25 100.00
45 INT112562 Binding of SELP 11 0.34 6.25 1.44 100.00
46 INT65075 Positive_regulation of Binding of SLC5A6 1 0.41 1.63 0.22 100.00
47 INT34058 Gene_expression of FMR1 5 0.75 5.11 0.26 100.00
48 INT65077 Binding of SLC5A6 1 0.31 1.63 0.22 100.00
49 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28 100.00
50 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33 100.00
51 INT15775 Positive_regulation of Ren1 50 0.69 22.38 6.19 100.00
52 INT171070 Positive_regulation of Hey2 8 0.05 10.12 1.96 100.00
53 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 100.00
54 INT49288 Positive_regulation of POLR2F 1 0.35 2.45 0.71 100.00
55 INT334125 Binding of D230030E09Rik 1 0.02 2.35 0.42 100.00
56 INT270089 Regulation of Binding of PSMG1 1 0.06 0.72 0 100.00
57 INT28560 Positive_regulation of Pacs1 1 0.07 1.33 0.09 100.00
58 INT216729 Positive_regulation of PSMG1 2 0.11 0.76 0.09 100.00
59 INT2583 Positive_regulation of PVT1 2 0.44 2.32 0.33 100.00
60 INT193611 Negative_regulation of SART1 1 0.41 0.68 0 100.00
61 INT36961 Negative_regulation of Positive_regulation of vs 1 0.24 1.02 0.35 100.00
62 INT97807 Negative_regulation of Regulation of CNR1 2 0.09 0.89 2.51 100.00
63 INT146661 Positive_regulation of D230030E09Rik 1 0.40 0.92 0.73 100.00
64 INT20425 Localization of Cpe 23 0.81 5.18 9.14 100.00
65 INT68592 Negative_regulation of asa 8 0.37 3.75 2.1 100.00
66 INT22003 Negative_regulation of Cpe 25 0.58 6.23 12.94 100.00
67 INT94127 Positive_regulation of Il18 14 0.69 14 7.47 100.00
68 INT252569 Positive_regulation of Rpe 8 0.38 1.26 0.15 100.00
69 INT27753 Positive_regulation of MMVP1 5 0.43 7.1 0.74 100.00
70 INT193612 Transcription of SART1 2 0.58 1.56 0.03 100.00
71 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84 100.00
72 INT1224 Gene_expression of Fabp6 34 0.64 23.69 9.08 100.00
73 INT19222 Positive_regulation of LCO 1 0.40 1.09 0.1 100.00
74 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 100.00
75 INT164178 Gene_expression of ADCY10 9 0.65 2.72 0.39 100.00
76 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 100.00
77 INT126714 Binding of Xpc 1 0.34 1.69 0.1 100.00
78 INT94190 Positive_regulation of ADCY10 5 0.49 3.17 0.58 100.00
79 INT25696 Negative_regulation of PSMG3 1 0.00 0.43 0.7 100.00
80 INT178917 Localization of PNC 1 0.26 0.42 0.04 100.00
81 INT152523 Gene_expression of Rpe 5 0.56 2.55 0.74 100.00
82 INT194104 Regulation of MKLN1 1 0.22 1.81 0 100.00
83 INT78941 Positive_regulation of DDX41 4 0.45 2.46 0.23 100.00
84 INT13999 Positive_regulation of Positive_regulation of NEUROD1 5 0.67 4.07 1.86 100.00
85 INT332731 Negative_regulation of Negative_regulation of Hr 1 0.08 1.02 0.12 100.00
86 INT27988 Negative_regulation of Positive_regulation of AGT 11 0.42 5.71 2.27 100.00
87 INT19993 Negative_regulation of Ren1 43 0.58 20.89 5.04 100.00
88 INT96624 Positive_regulation of Positive_regulation of Trpv1 62 0.70 20.5 34.28 100.00
89 INT7336 Positive_regulation of VIP 60 0.70 24.2 19.62 100.00
90 INT105620 Positive_regulation of Binding of Cd63 1 0.09 1.06 0.39 100.00
91 INT300726 Regulation of Pat 1 0.02 0.27 0.1 100.00
92 INT17904 Positive_regulation of Hts 9 0.39 2.91 0.15 100.00
93 INT15155 Regulation of Localization of NPPA 8 0.62 2.67 1.65 100.00
94 INT28891 Localization of Selp 13 0.60 8.23 2.83 100.00
95 INT105624 Localization of Cd63 4 0.52 1.81 1.21 100.00
96 INT67423 Regulation of Gene_expression of Selp 16 0.60 7.4 3.68 100.00
97 INT102522 Gene_expression of Cd63 6 0.71 3.72 0.63 100.00
98 INT105623 Regulation of Gene_expression of Cd63 1 0.08 0.81 0.25 100.00
99 INT73802 Regulation of Selp 17 0.60 8.72 3.51 100.00
100 INT105622 Regulation of Cd63 2 0.20 1.13 0.24 100.00
101 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 100.00
102 INT32513 Regulation of Localization of NPR1 3 0.36 0.84 0.81 100.00
103 INT252570 Regulation of Rpe 1 0.33 0.88 0.03 100.00
104 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 100.00
105 INT12923 Negative_regulation of Atp9a 17 0.35 7.87 3.52 100.00
106 INT270088 Negative_regulation of Binding of PSMG1 1 0.10 0.34 0.11 100.00
107 INT121337 Negative_regulation of HEY1 7 0.20 12.91 1.89 100.00
108 INT281293 Regulation of PSMG1 1 0.01 0.18 0.03 100.00
109 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 100.00
110 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49 100.00
111 INT695 Binding of POMC 304 0.48 56.66 126.85 100.00
112 INT5819 Regulation of Localization of Penk 64 0.62 6.69 57.68 100.00
113 INT5957 Positive_regulation of Cpe 65 0.69 21.07 51.22 100.00
114 INT2432 Positive_regulation of Cp 41 0.67 31.1 16.68 100.00
115 INT24820 Positive_regulation of Binding of POMC 9 0.67 2.98 4.6 100.00
116 INT2836 Positive_regulation of PAEP 51 0.67 26.69 4.57 100.00
117 INT12111 Negative_regulation of Hbb-ar 11 0.37 6.63 4.22 100.00
118 INT215599 Positive_regulation of Positive_regulation of Adora1 7 0.47 2.29 2.58 100.00
119 INT9764 Gene_expression of Adrb3 10 0.62 4.14 2.33 100.00
120 INT9735 Positive_regulation of Aecp 6 0.38 3.76 1.7 100.00
121 INT20950 Positive_regulation of PC 12 0.60 2.76 1.19 100.00
122 INT45674 Regulation of Gene_expression of Serpina6 3 0.14 0.86 1.14 100.00
123 INT45675 Regulation of Gene_expression of Shbg 6 0.15 4.65 1.03 100.00
124 INT38518 Positive_regulation of Negative_regulation of Grhpr 3 0.03 1.44 0.97 100.00
125 INT121333 Localization of HEY1 11 0.65 18.17 0.72 100.00
126 INT216770 Gene_expression of Cadps 3 0.34 0.86 0.6 100.00
127 INT159841 Binding of Sftpa1 1 0.25 0.84 0.4 100.00
128 INT106639 Negative_regulation of Negative_regulation of AVPR2 1 0.29 1.58 0.25 100.00
129 INT210926 Positive_regulation of Kcne2 1 0.02 0.49 0.22 100.00
130 INT190401 Gene_expression of SLC25A3 3 0.48 3.52 0.1 100.00
131 INT224345 Gene_expression of NUDT1 4 0.17 4.46 0 100.00
132 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7 99.98
133 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 99.98
134 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 99.98
135 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 99.96
136 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 99.96
137 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.96
138 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 99.96
139 INT5619 Positive_regulation of Gene_expression of Nppa 21 0.70 11.95 4.41 99.96
140 INT24141 Negative_regulation of Apcs 24 0.59 16.82 8.29 99.96
141 INT218 Positive_regulation of Th 245 0.70 40.5 120.1 99.96
142 INT36313 Localization of ADCY10 3 0.73 1.74 0.62 99.96
143 INT18412 Binding of PLEK 49 0.47 17.82 10.72 99.96
144 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 99.96
145 INT2482 Regulation of Positive_regulation of REN 4 0.59 2.62 0.91 99.96
146 INT288915 Regulation of Positive_regulation of AGT 1 0.41 0.82 0.08 99.96
147 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 99.92
148 INT159472 Localization of NPPB 32 0.79 33.67 3.59 99.92
149 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67 99.92
150 INT40160 Positive_regulation of Adora1 74 0.70 26.36 33.03 99.92
151 INT151102 Positive_regulation of CFTR 22 0.61 15.27 5.12 99.92
152 INT36622 Positive_regulation of Reb1 1 0.00 0.78 0.16 99.92
153 INT188884 Localization of DDX41 3 0.60 2.56 0.09 99.92
154 INT121335 Localization of SCD 10 0.68 6.81 1.51 99.92
155 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 99.92
156 INT655 Positive_regulation of Localization of REN 86 0.70 32.41 13.56 99.90
157 INT2629 Localization of Shbg 27 0.72 15.12 3.2 99.90
158 INT30011 Negative_regulation of Sepp1 18 0.54 4.65 3.54 99.90
159 INT122704 Positive_regulation of AEBP1 1 0.40 1 0.36 99.90
160 INT177482 Negative_regulation of Negative_regulation of BBS2 1 0.03 0.73 0 99.90
161 INT108535 Positive_regulation of TNNI1 7 0.67 5.54 2.12 99.88
162 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83 99.88
163 INT129671 Positive_regulation of Positive_regulation of TNNI1 1 0.37 0.53 0.14 99.88
164 INT5617 Localization of Nppa 266 0.81 83.51 83.89 99.84
165 INT11121 Positive_regulation of NPPA 64 0.70 34.09 11.96 99.84
166 INT214 Localization of AVP 370 0.81 208.51 91.09 99.84
167 INT35711 Positive_regulation of Sdcbp 110 0.60 50.45 22.11 99.84
168 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 99.84
169 INT7779 Negative_regulation of Adra2a 47 0.58 9.45 28 99.84
170 INT7059 Regulation of Adra2a 89 0.62 18.24 48.43 99.84
171 INT11102 Negative_regulation of Regulation of Adra2a 2 0.42 1.5 0.71 99.84
172 INT7132 Localization of NPPA 53 0.81 19.79 10.86 99.84
173 INT164659 Regulation of Cfh 1 0.04 0.68 0.09 99.84
174 INT1636 Gene_expression of Sct 58 0.77 16.14 11.57 99.84
175 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 99.84
176 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 99.84
177 INT292 Localization of Penk 876 0.81 88.44 669.14 99.84
178 INT12095 Negative_regulation of Edn1 26 0.59 12.01 8.79 99.84
179 INT186520 Gene_expression of CHKA 8 0.56 8.22 1 99.84
180 INT11099 Localization of NPR1 5 0.67 1.49 1.21 99.84
181 INT194105 Localization of MKLN1 1 0.37 0.37 0.18 99.84
182 INT33768 Positive_regulation of Cysltr1 87 0.46 54.66 33.52 99.84
183 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 99.82
184 INT17493 Binding of Ar 14 0.48 3.62 0.6 99.82
185 INT262999 Negative_regulation of Gene_expression of ADIPOQ 7 0.43 9.52 0.12 99.82
186 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 99.80
187 INT340828 Regulation of ADCY10 1 0.06 5.17 0.11 99.80
188 INT2774 Binding of Crp 241 0.48 195.89 44.39 99.80
189 INT45427 Positive_regulation of Cacna2d2 20 0.49 11.89 4.85 99.80
190 INT38612 Negative_regulation of Bpq1 1 0.01 1.42 0.07 99.80
191 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48 99.80
192 INT170260 Regulation of Gene_expression of SELP 3 0.21 2.67 0.11 99.80
193 INT37652 Positive_regulation of Pgr 29 0.59 9.09 4.67 99.80
194 INT63423 Negative_regulation of Gene_expression of SELP 13 0.55 1.98 0.57 99.80
195 INT210709 Regulation of Itgam 8 0.28 9.21 1.76 99.80
196 INT185691 Positive_regulation of WDTC1 24 0.48 12.57 6.49 99.80
197 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 99.78
198 INT32903 Negative_regulation of PPAP2A 14 0.48 5.02 7.2 99.78
199 INT1179 Negative_regulation of Ace 157 0.59 67.03 30.46 99.76
200 INT59 Regulation of Adrb1 25 0.42 8.32 9.78 99.76
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