D:Heat Stress Disorders

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Disease Term
Synonyms CRAMP HEAT, Cramps Heat, Disorder Heat Stress, DISORDERS HEAT STRESS, Heat Cramp, Heat Cramps, Heat Stress, Heat Stress Disorder, Heat Stress Syndrome, Heat Stress Syndromes, Heat Stresses
Documents 121
Hot Single Events 118
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Heat Stress Disorders. They are ordered first by their relevance to Heat Stress Disorders and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT140314 PCSK7 Positive_regulation of LDHA 1 0.07 1.6 1.4 99.92
2 INT296324 NFE2L2 Regulation of GSTK1 1 0.01 0.91 0.14 84.88
3 INT255761 hs Regulation of TNF 1 0.07 1.33 0 82.52
4 INT255760 Ptch1 Regulation of TNF 1 0.13 1.33 0 82.40
5 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 79.36
6 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 77.04
7 INT255747 hs Positive_regulation of Phosphorylation of Gopc 1 0.07 1.33 0 76.72
8 INT255752 hs Positive_regulation of Phosphorylation of Slc2a4 1 0.08 1.32 0 76.72
9 INT255753 Ptch1 Positive_regulation of Phosphorylation of Gopc 1 0.13 1.33 0 76.60
10 INT255749 Ptch1 Positive_regulation of Phosphorylation of Slc2a4 1 0.15 1.32 0 76.60
11 INT94355 NOVA2 Positive_regulation of Dbi 1 0.00 0.15 0.18 75.00
12 INT94353 Crh Negative_regulation of Positive_regulation of Dbi 1 0.03 0.14 0.08 75.00
13 INT94354 Crh Negative_regulation of Dbi 1 0.03 0.14 0.08 75.00
14 INT255751 hs Regulation of Ins1 1 0.05 1.24 0 65.32
15 INT255734 Ptch1 Regulation of Ins1 1 0.09 1.46 0 65.20
16 INT250038 Binding of Alb and Tbpl1 1 0.03 0.28 0 54.48
17 INT174959 Binding of IL6 and Positive_regulation of Transcription of HSP90B2P 1 0.02 0.9 0 43.96
18 INT194407 Binding of CALCA and MTCP1NB 1 0.01 0 0.51 26.20
19 INT194396 CALCA Positive_regulation of Binding of CALCA and MTCP1NB 1 0.01 0 0.51 26.20
20 INT253935 Binding of PTPLA and Trpv1 1 0.14 1.25 0.65 24.48
21 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18 5.00
22 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8 5.00
23 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91 5.00
24 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84 5.00
25 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29 5.00
26 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18 5.00
27 INT194402 Binding of IGKV1D-8 and DCLK3 1 0.06 0 0.7 5.00
28 INT194410 Binding of CALCA and LZTS1 1 0.06 0 0.67 5.00
29 INT171909 MAPK8 Positive_regulation of Gene_expression of MAPK1 1 0.08 1.55 0.52 5.00
30 INT171910 MAPK1 Positive_regulation of MAPK9 1 0.10 1.55 0.52 5.00
31 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52 5.00
32 INT171914 MAPK8IP3 Positive_regulation of Gene_expression of MAPK1 1 0.06 1.55 0.52 5.00
33 INT194405 DCLK3 Positive_regulation of Gene_expression of RAMP1 1 0.16 0.09 0.43 5.00
34 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37 5.00
35 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 5.00
36 INT194406 Binding of RAMP1 and RPL34P34 1 0.00 0 0.29 5.00
37 INT171912 MAPK8IP3 Positive_regulation of MAPK9 1 0.06 0.78 0.26 5.00
38 INT171907 MAPK8 Positive_regulation of Gene_expression of MAPK14 1 0.06 0.77 0.26 5.00
39 INT171911 MAPK8IP3 Positive_regulation of Gene_expression of MAPK14 1 0.05 0.77 0.26 5.00
40 INT171913 MAPK8 Positive_regulation of MAPK9 1 0.07 0.78 0.26 5.00
41 INT194404 Binding of RAMP2 and DCLK3 1 0.07 0 0.22 5.00
42 INT326575 Nrg1 Positive_regulation of Gene_expression of JUN 1 0.38 0.86 0.2 5.00
43 INT255736 Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.14 2.31 0.16 5.00
44 INT253122 Ins1 Positive_regulation of Akt1 2 0.15 1.81 0.14 5.00
45 INT255754 Negative_regulation of Ins1 Positive_regulation of Akt1 1 0.14 1.73 0.1 5.00
46 INT326574 Binding of Akt1 and Hsp90ab1 1 0.13 0.17 0.08 5.00
47 INT326573 Zic2 Positive_regulation of Localization of Hsf1 1 0.01 0.95 0.07 5.00
48 INT187845 Binding of ESR1 and Esr2 1 0.01 0.17 0.06 5.00
49 INT326571 Binding of Hsf1 and Hsp90ab1 1 0.16 1.19 0.03 5.00
50 INT255756 Ptch1 Positive_regulation of Phosphorylation of Pik3r1 1 0.16 1.08 0.03 5.00
51 INT255733 Ptch1 Positive_regulation of Pik3r1 1 0.16 1.08 0.03 5.00
52 INT326570 Hsp90ab1 Regulation of Csprs 1 0.08 1.17 0.03 5.00
53 INT255758 Ptch1 Positive_regulation of Akt1 1 0.21 1.14 0 5.00
54 INT255732 Ptch1 Positive_regulation of hs 1 0.06 1.26 0 5.00
55 INT255742 hs Positive_regulation of Phosphorylation of Akt1 1 0.10 1.11 0 5.00
56 INT349174 Mapk14 Positive_regulation of Phosphorylation of Hspb1 1 0.35 0.2 0 5.00
57 INT255738 hs Positive_regulation of Phosphorylation of Ins1 1 0.05 1.34 0 5.00
58 INT255755 Ptch1 Regulation of Positive_regulation of Ins1 1 0.05 0.28 0 5.00
59 INT218040 Binding of DNAH8 and PRSS3 1 0.01 1.32 0 5.00
60 INT255748 Hspa1a Positive_regulation of Positive_regulation of hs 1 0.11 0.99 0 5.00
61 INT349173 Positive_regulation of Stzid Positive_regulation of Positive_regulation of Hspb1 1 0.03 0.3 0 5.00
62 INT297124 Binding of INCENP and Hephl1 1 0.00 0.17 0 5.00
63 INT255737 hs Positive_regulation of Hspa1a 1 0.09 1.1 0 5.00
64 INT255745 Gene_expression of Hspa1a Positive_regulation of Phosphorylation of Akt1 1 0.31 0.56 0 5.00
65 INT255744 Binding of hs and Ptch1 1 0.06 1.32 0 5.00
66 INT176919 Binding of DLD and Bpifa2 1 0.00 0.08 0 5.00
67 INT255750 Ptch1 Positive_regulation of Ins1 1 0.10 0.35 0 5.00
68 INT218041 Positive_regulation of Binding of DNAH8 and PRSS3 1 0.01 1.37 0 5.00
69 INT255741 Ptch1 Positive_regulation of Phosphorylation of Ins1 1 0.09 2.21 0 5.00
70 INT176920 DLD Positive_regulation of Binding of Bpifa2 1 0.00 0.08 0 5.00
71 INT255735 Ptch1 Positive_regulation of Phosphorylation of Akt1 1 0.27 2.83 0 5.00
72 INT255746 Hspa1a Positive_regulation of Positive_regulation of Ptch1 1 0.19 0.99 0 5.00
73 INT255739 Ptch1 Positive_regulation of Gene_expression of Hspa1a 1 0.18 0.75 0 5.00
74 INT255759 Ptch1 Positive_regulation of Phosphorylation of hs 1 0.06 1.34 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Heat Stress Disorders. They are ordered first by their pain relevance and then by number of times they were reported in Heat Stress Disorders. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14 100.00
2 INT96916 Negative_regulation of Phosphorylation of Mapk8 16 0.52 9.68 1.97 100.00
3 INT738 Regulation of POMC 459 0.62 111.19 243.74 100.00
4 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14 100.00
5 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76 99.98
6 INT4236 Negative_regulation of GLYAT 9 0.57 4.37 3.74 99.98
7 INT79721 Positive_regulation of Gene_expression of Hspa1a 13 0.69 10.69 1.17 99.98
8 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.92
9 INT4563 Positive_regulation of Regulation of Prl 20 0.70 4.2 8.1 99.92
10 INT38255 Localization of Chkb 32 0.80 10.98 11.07 99.84
11 INT38256 Negative_regulation of Localization of Chkb 10 0.56 3.58 4.11 99.84
12 INT38254 Positive_regulation of Localization of Trib3 14 0.45 6.14 6.99 99.84
13 INT38348 Positive_regulation of Localization of Chkb 9 0.64 2.75 3.37 99.84
14 INT38253 Localization of Trib3 35 0.63 10.28 15.42 99.84
15 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44 99.82
16 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03 99.82
17 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 99.76
18 INT58438 Positive_regulation of Hspa1a 8 0.68 6.24 1.91 99.76
19 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.72
20 INT140912 Positive_regulation of Nexn 6 0.59 3.5 0.2 99.72
21 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 99.72
22 INT58435 Gene_expression of Hspa1a 19 0.78 15.35 4.45 99.72
23 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.72
24 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 99.70
25 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98 99.70
26 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2 99.70
27 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 99.70
28 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.68
29 INT96917 Positive_regulation of Mapk14 261 0.70 173.29 88.79 99.68
30 INT96911 Positive_regulation of Phosphorylation of Mapk14 46 0.70 43.03 15.15 99.68
31 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.60
32 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 99.60
33 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86 99.60
34 INT119510 Localization of GLYAT 1 0.68 0.86 0.07 99.50
35 INT84700 Positive_regulation of HSP90B2P 34 0.67 30.22 4.07 99.50
36 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 99.44
37 INT96914 Phosphorylation of Mapk14 168 0.82 108.46 53.32 99.44
38 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 99.42
39 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.38
40 INT626 Localization of CALCA 289 0.81 125.39 221.15 99.16
41 INT20260 Positive_regulation of Chkb 41 0.64 21.48 18.53 99.12
42 INT1414 Regulation of Oprl1 169 0.62 32.05 139.99 98.96
43 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 98.94
44 INT28923 Negative_regulation of Ldha 8 0.58 4.94 3.11 98.92
45 INT79724 Localization of Chka 1 0.54 1.04 0.22 98.86
46 INT96924 Positive_regulation of Hspg2 40 0.49 14.5 12.32 98.76
47 INT64161 Positive_regulation of Prkca 213 0.70 85.06 129.91 98.76
48 INT4449 Positive_regulation of NA 179 0.55 40.26 37.82 98.76
49 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 98.76
50 INT9383 Localization of TRPV1 98 0.81 33.23 46.24 98.66
51 INT4891 Transcription of Calca 81 0.72 35.27 53.75 98.64
52 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 98.64
53 INT64171 Regulation of CPOX 109 0.36 55.36 32.96 98.32
54 INT2389 Regulation of PTGS1 86 0.61 31.23 28.95 98.32
55 INT79720 Positive_regulation of Cat 57 0.70 31.81 10.11 97.76
56 INT79722 Regulation of Cat 14 0.62 5.88 2.86 97.76
57 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 97.58
58 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 97.56
59 INT79723 Positive_regulation of Sod2 34 0.70 24.61 3.92 97.50
60 INT79725 Regulation of Sod2 8 0.61 4.95 0.54 97.50
61 INT234928 Phosphorylation of Hspb1 3 0.72 17.04 0.65 97.20
62 INT349165 Positive_regulation of Phosphorylation of Hspb1 1 0.61 4.56 0.13 97.20
63 INT2442 Localization of Mb 38 0.80 24.74 6.33 96.84
64 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 96.60
65 INT2532 Negative_regulation of Cebpz 98 0.00 53.06 28.57 96.60
66 INT71496 Positive_regulation of Hspb1 15 0.69 14.7 6.86 96.60
67 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 96.54
68 INT131475 Regulation of Hspa1b 1 0.31 2.01 1.14 96.36
69 INT131476 Negative_regulation of Hspa1b 1 0.30 1.07 0.61 96.36
70 INT242062 Positive_regulation of Positive_regulation of Scap 1 0.00 1.07 0 96.00
71 INT232829 Positive_regulation of Scap 6 0.02 2.97 0.11 95.68
72 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45 95.60
73 INT5979 Gene_expression of Oprd1 428 0.78 75.64 320.32 95.40
74 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 95.12
75 INT443 Localization of POMC 1020 0.81 284.52 443.17 94.92
76 INT19527 Negative_regulation of Gene_expression of Il1a 26 0.51 15.4 11.58 94.40
77 INT35121 Negative_regulation of Gene_expression of Sdcbp 6 0.43 2.4 1.83 94.40
78 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 94.32
79 INT5989 Positive_regulation of Dbi 79 0.49 24.38 32.56 94.24
80 INT10534 Positive_regulation of Trib3 209 0.60 78.75 81.48 94.08
81 INT10533 Positive_regulation of Positive_regulation of Trib3 24 0.42 6.59 9.2 94.08
82 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 93.92
83 INT35120 Gene_expression of Sdcbp 68 0.67 21.33 13.96 93.92
84 INT113913 Binding of Hephl1 23 0.27 1.57 0.19 93.68
85 INT10546 Positive_regulation of Prss12 12 0.44 4.57 10.05 93.28
86 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38 92.16
87 INT20345 Gene_expression of Dbi 136 0.78 56.41 46.2 92.12
88 INT8160 Gene_expression of Prss12 20 0.67 4.83 8.17 91.60
89 INT158 Localization of Prl 2431 0.81 378.96 952.2 91.60
90 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 91.60
91 INT5988 Localization of Dbi 74 0.81 17.52 24.09 91.28
92 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92 90.40
93 INT170142 Regulation of Protein_catabolism of Tnf 1 0.44 1.53 0.13 89.48
94 INT50272 Positive_regulation of Cotl1 24 0.40 6.57 2.77 88.96
95 INT110025 Positive_regulation of Positive_regulation of Mapk14 39 0.63 20.67 12.71 88.84
96 INT235828 Binding of Hspg2 4 0.25 2.24 0.89 88.48
97 INT143535 Protein_catabolism of Tnf 2 0.86 3.43 0.33 87.52
98 INT133636 Negative_regulation of AKR1E2 1 0.07 0.89 1.09 86.28
99 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62 86.12
100 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 85.96
101 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 85.92
102 INT8747 Positive_regulation of Ins1 221 0.69 154.28 35.15 85.76
103 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 85.64
104 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 85.48
105 INT32541 Positive_regulation of Positive_regulation of Dbi 2 0.39 0.5 1.14 85.12
106 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 85.12
107 INT121234 Negative_regulation of DDAH2 5 0.57 1.64 2.15 85.12
108 INT15724 Negative_regulation of Fn1 15 0.53 5.61 3.87 84.60
109 INT296623 Positive_regulation of Cdh1 2 0.35 1.88 0.09 82.80
110 INT159432 Gene_expression of hs 3 0.16 5 0.27 82.52
111 INT65919 Gene_expression of Ptch1 11 0.75 6.47 0.56 82.40
112 INT246978 Binding of PTPLA 3 0.18 3.62 2.79 82.08
113 INT16286 Positive_regulation of GHR 8 0.60 4.04 2.31 81.96
114 INT107430 Localization of Cxcl2 8 0.66 7.05 1.2 81.92
115 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 81.72
116 INT119195 Binding of Cotl1 11 0.14 6.77 2.21 80.96
117 INT66919 Positive_regulation of HSF1 27 0.69 14.78 3.24 80.88
118 INT227273 Localization of Adipoq 22 0.72 18.04 1.72 80.68
119 INT55434 Positive_regulation of Gene_expression of HSP90B2P 14 0.38 10.91 4.83 79.60
120 INT695 Binding of POMC 304 0.48 56.66 126.85 79.52
121 INT173693 Localization of Gopc 249 0.65 70.49 38.81 79.16
122 INT27882 Gene_expression of HSP90B2P 52 0.75 36.51 9.59 78.80
123 INT296610 Negative_regulation of Duox2 1 0.06 2.5 0.09 77.60
124 INT19511 Localization of Il6 212 0.81 118.17 67.67 77.44
125 INT55255 Positive_regulation of Localization of Il6 48 0.69 24.88 12.76 77.44
126 INT7132 Localization of NPPA 53 0.81 19.79 10.86 77.16
127 INT101815 Binding of KEAP1 6 0.44 5.29 0.39 77.04
128 INT176894 Localization of SDS 1 0.03 0.08 0 76.36
129 INT101825 Binding of NFE2L2 9 0.37 3.82 0.48 76.32
130 INT214 Localization of AVP 370 0.81 208.51 91.09 76.24
131 INT5512 Negative_regulation of Dbi 32 0.36 7.33 9.1 76.08
132 INT197569 Protein_catabolism of NFE2L2 10 1.00 3.11 0.1 75.92
133 INT104396 Positive_regulation of Positive_regulation of Akt1 44 0.55 14.78 8.69 75.76
134 INT278334 Negative_regulation of Hsp90ab1 3 0.30 4.34 0.68 75.72
135 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17 75.68
136 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 75.08
137 INT11746 Positive_regulation of Il1a 65 0.63 42.94 23.54 75.04
138 INT720 Positive_regulation of POMC 807 0.70 237.37 353.83 75.00
139 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3 75.00
140 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84 75.00
141 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49 75.00
142 INT218696 Negative_regulation of Phosphorylation of Smad2 3 0.42 4.36 0.92 74.32
143 INT127112 Phosphorylation of Smad2 19 0.80 11.01 5.36 74.32
144 INT175526 Phosphorylation of Gopc 73 0.53 21.08 7.86 74.32
145 INT255722 Phosphorylation of Slc2a4 1 0.46 1.3 0 74.32
146 INT340897 Positive_regulation of Hspb2 3 0.34 1.86 0.26 73.92
147 INT62822 Positive_regulation of Gene_expression of SELE 22 0.66 28.04 4.97 73.36
148 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 72.84
149 INT49196 Gene_expression of SELE 105 0.78 107.29 22.92 72.84
150 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69 72.32
151 INT101821 Localization of KEAP1 4 0.71 0.93 0.28 72.00
152 INT112029 Positive_regulation of Pik3r1 90 0.67 38.76 20.95 71.12
153 INT53066 Positive_regulation of Positive_regulation of EPO 4 0.49 2.38 0.95 70.92
154 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38 70.84
155 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 70.32
156 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 69.64
157 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 68.52
158 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 68.24
159 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 68.24
160 INT171929 Positive_regulation of Positive_regulation of ELF1 1 0.07 0.74 0.15 67.52
161 INT171923 Positive_regulation of ELF1 2 0.28 0.86 0.19 67.00
162 INT3130 Transcription of LH 12 0.67 2.08 3.82 66.48
163 INT171921 Gene_expression of ELF1 1 0.11 0.74 0.15 66.44
164 INT171927 Positive_regulation of Gene_expression of ELF1 1 0.10 0.74 0.15 66.44
165 INT141542 Negative_regulation of Pin1 2 0.29 10.92 1.1 65.28
166 INT64233 Regulation of Trp53 35 0.62 27.11 1.53 64.80
167 INT296612 Regulation of Pin1 1 0.23 2.5 0.39 64.56
168 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 64.24
169 INT46206 Positive_regulation of Scn10a 11 0.60 6.57 1.38 64.24
170 INT206938 Regulation of Casp9 5 0.44 3.99 0.12 64.16
171 INT51654 Regulation of Bad 21 0.40 12.18 4.06 63.28
172 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 63.20
173 INT250026 Regulation of Hspg2 1 0.05 0.16 0.03 61.80
174 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 61.48
175 INT73175 Positive_regulation of Gene_expression of Hspa1b 3 0.48 2.53 2.72 60.56
176 INT159378 Localization of Hspg2 6 0.80 0.9 1.35 60.56
177 INT73179 Gene_expression of Hspa1b 10 0.73 6.24 6.04 60.16
178 INT131474 Regulation of Gene_expression of Hspa1b 1 0.31 1.51 1 60.16
179 INT18884 Regulation of RYBP 25 0.38 11.43 23.2 59.32
180 INT86780 Positive_regulation of Hmox1 145 0.70 117.09 31.18 59.12
181 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 59.12
182 INT28021 Positive_regulation of Adipoq 42 0.67 30.79 3.58 59.12
183 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 58.48
184 INT81930 Positive_regulation of Gene_expression of HSF1 4 0.66 4.07 0.88 58.48
185 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 58.48
186 INT81921 Gene_expression of HSF1 17 0.76 9.19 1.08 58.48
187 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 57.60
188 INT105021 Binding of GOPC 187 0.40 60.39 20.38 55.44
189 INT171922 Positive_regulation of Binding of GOPC 5 0.44 1.31 0.34 55.44
190 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 55.12
191 INT81928 Positive_regulation of Binding of HSF1 4 0.49 3.04 1.67 55.04
192 INT81926 Binding of HSF1 10 0.47 5.05 1.53 55.04
193 INT152436 Positive_regulation of Gene_expression of HSPD1 12 0.67 10.06 2.16 54.84
194 INT85417 Positive_regulation of Gene_expression of IK 17 0.09 9.38 5.73 53.68
195 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 52.60
196 INT6176 Positive_regulation of Htr1a 117 0.67 28.23 66.17 52.44
197 INT7000 Positive_regulation of Htr2a 42 0.67 9.48 18.7 52.44
198 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68 51.24
199 INT153257 Regulation of Ptch1 6 0.36 5.92 0.67 50.64
200 INT255720 Regulation of hs 3 0.11 5.33 0.08 50.64
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