D:Helicobacter Infection

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Disease Term
Synonyms H Pylori, HELICOBACTER INFECTIONS, Helicobacter Pylori, INFECTION HELICOBACTER, Infections Helicobacter, NONEROSIVE GASTRITIS
Documents 33
Hot Single Events 34
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Helicobacter Infection. They are ordered first by their relevance to Helicobacter Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT266616 Il4 Positive_regulation of Il12a 1 0.01 0.4 0.17 38.96
2 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23 5.00
3 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41 5.00
4 INT266617 Binding of GJC1 and Tjp1 1 0.41 0.28 0.03 5.00
5 INT235075 Ptger2 Positive_regulation of Positive_regulation of Nos2 1 0.00 0.43 0 5.00
6 INT235077 Akt1 Positive_regulation of Phosphorylation of Gsk3b 1 0.07 0.53 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Helicobacter Infection. They are ordered first by their pain relevance and then by number of times they were reported in Helicobacter Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 100.00
2 INT235072 Binding of Hfgi1 2 0.14 3.35 0.13 100.00
3 INT235061 Gene_expression of Hfgi1 2 0.26 1.85 0.05 100.00
4 INT235059 Positive_regulation of Gene_expression of Hfgi1 1 0.04 0.49 0.05 100.00
5 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 99.34
6 INT90350 Gene_expression of Gast 27 0.78 14.07 4.74 99.32
7 INT90347 Regulation of Gene_expression of Gast 2 0.54 1.86 0.26 99.32
8 INT123177 Positive_regulation of Gene_expression of Gast 4 0.70 1.37 0.09 99.28
9 INT86583 Localization of PROSC 1 0.55 1.84 0.26 98.52
10 INT90348 Regulation of Gast 2 0.61 1.41 0.42 98.48
11 INT190367 Gene_expression of Defa1 10 0.75 8.92 1.5 98.40
12 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 95.24
13 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 94.92
14 INT89852 Localization of Nos2 22 0.78 14.89 2.56 94.64
15 INT90351 Negative_regulation of Gast 5 0.59 2.85 0.89 92.32
16 INT151229 Positive_regulation of Cxam 10 0.15 6.13 1.35 91.60
17 INT58679 Gene_expression of Odc1 13 0.78 9.55 0.45 88.56
18 INT266600 Negative_regulation of Gene_expression of Odc1 1 0.51 1.06 0.15 88.56
19 INT256598 Gene_expression of DEFB103A 8 0.65 5.06 1.49 87.36
20 INT123178 Negative_regulation of Gene_expression of Gast 1 0.43 0.69 0 85.24
21 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 85.20
22 INT96155 Gene_expression of Cd86 134 0.77 50.56 17.13 85.20
23 INT87434 Gene_expression of Sell 38 0.77 21.95 8.51 85.20
24 INT112166 Localization of Gast 15 0.72 8.86 2.91 85.04
25 INT108780 Positive_regulation of Gene_expression of Ptger2 94 0.49 59.71 16.22 81.56
26 INT122888 Positive_regulation of Transcription of IFNA1 5 0.45 3.51 1.59 81.16
27 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 81.00
28 INT107307 Transcription of IFNA1 30 0.52 18.16 9.61 80.76
29 INT13354 Transcription of TNF 108 0.72 85.81 42.32 80.76
30 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82 80.64
31 INT266594 Gene_expression of Igtp 1 0.53 0.53 0.16 80.40
32 INT266601 Gene_expression of Iigp1 1 0.01 0.54 0.16 80.40
33 INT203133 Gene_expression of Cxam 3 0.07 6.17 1.22 80.24
34 INT235070 Positive_regulation of Gene_expression of Cxam 1 0.03 1.35 0.1 80.24
35 INT235056 Negative_regulation of Gene_expression of Cxam 1 0.03 0.52 0.03 76.16
36 INT316686 Negative_regulation of Spg21 2 0.05 3.34 0.8 74.72
37 INT90349 Positive_regulation of Negative_regulation of Gast 1 0.69 0.68 0.2 71.96
38 INT47628 Regulation of CEL 9 0.60 4.5 1.85 68.36
39 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 65.60
40 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 65.60
41 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 64.60
42 INT346907 Positive_regulation of Gene_expression of DEFA5 1 0.04 1.03 0.06 58.40
43 INT125006 Gene_expression of DEFA5 2 0.05 3.38 0.38 58.20
44 INT346901 Regulation of Gene_expression of DEFA5 1 0.02 1.04 0.06 58.20
45 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22 55.20
46 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3 55.20
47 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 51.28
48 INT235058 Localization of Wnt1 1 0.64 0.56 0 50.96
49 INT10188 Positive_regulation of Il2ra 19 0.45 11.6 3.37 50.00
50 INT125013 Regulation of S100a8 9 0.26 7.93 3.21 50.00
51 INT125015 Regulation of Positive_regulation of Il2ra 1 0.06 0 0 50.00
52 INT125014 Negative_regulation of Phosphorylation of S100a8 1 0.42 0 0 50.00
53 INT125016 Phosphorylation of S100a8 1 0.80 0 0 50.00
54 INT125012 Regulation of Phosphorylation of S100a8 1 0.26 0 0 50.00
55 INT82448 Gene_expression of S100a8 246 0.77 236.72 84.02 46.16
56 INT63365 Gene_expression of Spg21 21 0.65 12.9 7.37 43.20
57 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 42.80
58 INT77945 Regulation of Gene_expression of Il12a 19 0.58 6.55 6.4 40.68
59 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 40.24
60 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 40.24
61 INT103446 Gene_expression of Krt10 4 0.39 2.21 0.29 40.24
62 INT160673 Gene_expression of Ambp 16 0.49 19.49 2.3 26.96
63 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21 26.96
64 INT266610 Gene_expression of Tff1 3 0.62 3.88 0.1 26.96
65 INT266595 Gene_expression of Ddb1 1 0.33 1.16 0 26.96
66 INT266607 Gene_expression of Rev1 1 0.02 1.17 0 26.96
67 INT39999 Gene_expression of Gla 7 0.59 3.27 0.69 25.28
68 INT235063 Positive_regulation of Gene_expression of Gla 2 0.04 0.81 0.39 25.28
69 INT116605 Binding of Nos2 28 0.37 16.88 8.18 21.12
70 INT235057 Positive_regulation of Negative_regulation of Apc 2 0.30 0.66 0.05 13.12
71 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91 11.16
72 INT159140 Positive_regulation of Gene_expression of Tjp1 11 0.61 5.04 0.5 10.84
73 INT149031 Gene_expression of Tjp1 43 0.75 19.1 2.06 10.44
74 INT47075 Positive_regulation of Ptger2 142 0.70 78.55 25.47 9.52
75 INT266596 Regulation of Gene_expression of Igsf5 1 0.19 0.32 0.06 7.24
76 INT266599 Gene_expression of Igsf5 1 0.24 0.32 0.06 7.24
77 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 5.00
78 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
79 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
80 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
81 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 5.00
82 INT85640 Gene_expression of Tg(CAG-EGFP)D4Nagy 1138 0.72 311.58 119.18 5.00
83 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
84 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
85 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
86 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
87 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 5.00
88 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
89 INT49436 Binding of TRPV1 145 0.48 38.35 55.08 5.00
90 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 5.00
91 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
92 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 5.00
93 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 5.00
94 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 5.00
95 INT97596 Localization of S100a8 94 0.78 90.69 40.41 5.00
96 INT114881 Gene_expression of Akt1 227 0.78 102.49 31.81 5.00
97 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
98 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31 5.00
99 INT93738 Gene_expression of Tnfrsf1a 63 0.74 57.66 23.09 5.00
100 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
101 INT111401 Positive_regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 134 0.61 34.87 20.15 5.00
102 INT61519 Gene_expression of Mpo 112 0.78 89.29 18.22 5.00
103 INT116978 Gene_expression of CCR6 53 0.78 56 17.73 5.00
104 INT110767 Localization of Mcpt1 43 0.68 24.3 16.74 5.00
105 INT124371 Negative_regulation of Gsk3b 170 0.55 87.92 15.51 5.00
106 INT25396 Localization of Ptger2 83 0.78 46.81 14.81 5.00
107 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8 5.00
108 INT124372 Gene_expression of Gsk3b 164 0.75 95.64 14.35 5.00
109 INT109304 Positive_regulation of Phosphorylation of Akt1 113 0.69 40.92 13.49 5.00
110 INT51265 Phosphorylation of TNF 32 0.81 25.33 10.75 5.00
111 INT16404 Regulation of CD4 54 0.61 33.05 10.29 5.00
112 INT61171 Gene_expression of S100A8 92 0.76 57.74 9.98 5.00
113 INT135372 Positive_regulation of Gsk3b 72 0.70 50.03 9.28 5.00
114 INT87193 Gene_expression of Tnfrsf1b 30 0.58 29.4 9.22 5.00
115 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 5.00
116 INT85751 Positive_regulation of Positive_regulation of Nos2 40 0.60 23.53 7.72 5.00
117 INT6596 Positive_regulation of HLA-DRB1 33 0.61 27.01 7.26 5.00
118 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08 5.00
119 INT181489 Localization of Spg21 16 0.12 10.89 6.84 5.00
120 INT52695 Regulation of Ptgs2 20 0.42 8.72 5.71 5.00
121 INT124370 Positive_regulation of Gene_expression of Gsk3b 47 0.67 24.56 5.4 5.00
122 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 5.00
123 INT135374 Binding of Gsk3b 46 0.48 24.36 4.75 5.00
124 INT134657 Localization of Akt1 37 0.68 11.58 4.62 5.00
125 INT125005 Negative_regulation of SLPI 9 0.42 5.79 4.43 5.00
126 INT167284 Phosphorylation of Gsk3b 88 0.82 36.03 4.21 5.00
127 INT123908 Positive_regulation of HLA-DQB1 12 0.21 10.5 3.71 5.00
128 INT47674 Positive_regulation of Myoz1 21 0.54 4.37 3.57 5.00
129 INT148288 Gene_expression of CCL15 9 0.25 6.53 3.41 5.00
130 INT134786 Gene_expression of Adam10 17 0.68 7.61 3.29 5.00
131 INT25393 Positive_regulation of Localization of Ptger2 19 0.32 9.69 3.23 5.00
132 INT62112 Binding of S100A8 37 0.36 17.18 3.16 5.00
133 INT68961 Positive_regulation of Positive_regulation of Ptger2 12 0.44 6.91 3.02 5.00
134 INT58527 Gene_expression of Prtn3 20 0.71 15.99 2.9 5.00
135 INT24895 Positive_regulation of LYZ 25 0.70 17.92 2.64 5.00
136 INT76341 Negative_regulation of Positive_regulation of Ptger2 12 0.25 6.63 2.42 5.00
137 INT60942 Localization of S100A8 12 0.78 12.23 2.39 5.00
138 INT105536 Regulation of Myoz1 6 0.17 3.45 2.01 5.00
139 INT140053 Positive_regulation of Cish 9 0.41 2.4 2 5.00
140 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97 5.00
141 INT77805 Regulation of Gene_expression of Ptgs2 6 0.51 2.7 1.92 5.00
142 INT84512 Binding of Myoz1 7 0.30 4.48 1.7 5.00
143 INT138699 Gene_expression of Pdgfc 5 0.30 3.32 1.46 5.00
144 INT46736 Negative_regulation of Odc1 10 0.51 7.6 1.39 5.00
145 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3 5.00
146 INT244123 Localization of Defa1 5 0.78 3.42 1.23 5.00
147 INT263019 Gene_expression of DEFA6 4 0.25 4.14 1.17 5.00
148 INT233561 Gene_expression of Clu 14 0.66 45.63 1.07 5.00
149 INT235939 Gene_expression of Aqp5 8 0.45 4.7 1.06 5.00
150 INT73572 Positive_regulation of S100A8 10 0.67 6.6 1 5.00
151 INT134660 Positive_regulation of Localization of Akt1 10 0.32 6.33 0.94 5.00
152 INT213501 Negative_regulation of Gene_expression of Defa1 4 0.42 4.74 0.93 5.00
153 INT263027 Positive_regulation of DEFB103A 5 0.45 2.89 0.92 5.00
154 INT89856 Positive_regulation of Localization of Nos2 6 0.49 1.79 0.9 5.00
155 INT181637 Gene_expression of CMA1 10 0.66 4.16 0.72 5.00
156 INT235069 Localization of Cdh1 9 0.74 3.81 0.71 5.00
157 INT187793 Gene_expression of Csf1 10 0.77 22.35 0.66 5.00
158 INT189438 Regulation of Gene_expression of Kit 10 0.45 4.94 0.61 5.00
159 INT235079 Negative_regulation of Phosphorylation of TNF 2 0.41 1.16 0.6 5.00
160 INT71497 Binding of Hspa1b 3 0.08 1.43 0.58 5.00
161 INT282380 Binding of Atg16l1 4 0.38 2.06 0.58 5.00
162 INT81645 Positive_regulation of Gene_expression of Ctnnb1 6 0.63 3.78 0.47 5.00
163 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46 5.00
164 INT159146 Regulation of Gene_expression of Tjp1 13 0.44 6.91 0.45 5.00
165 INT235064 Regulation of Positive_regulation of Gsk3b 3 0.41 1.5 0.42 5.00
166 INT213502 Negative_regulation of Defa1 2 0.02 1.97 0.41 5.00
167 INT86584 Phosphorylation of S100A8 10 0.80 4.99 0.41 5.00
168 INT95872 Localization of Ctnnb1 7 0.74 2.75 0.4 5.00
169 INT204012 Regulation of Negative_regulation of Gsk3b 4 0.42 4.51 0.39 5.00
170 INT83212 Positive_regulation of Gene_expression of Mki67 21 0.55 17.53 0.39 5.00
171 INT140336 Negative_regulation of Csf1 3 0.43 3.64 0.36 5.00
172 INT245272 Gene_expression of Cldn3 8 0.62 1.73 0.36 5.00
173 INT228713 Localization of Hspb8 3 0.01 1.51 0.34 5.00
174 INT164192 Localization of SLPI 4 0.73 1.51 0.32 5.00
175 INT346906 Negative_regulation of Localization of SLPI 1 0.22 0.68 0.32 5.00
176 INT287775 Transcription of Ghrl 3 0.41 1.27 0.31 5.00
177 INT327723 Negative_regulation of Etohd1 1 0.03 0.73 0.3 5.00
178 INT263025 Positive_regulation of Gene_expression of DEFA6 2 0.16 1 0.28 5.00
179 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28 5.00
180 INT346896 Binding of Nod2 1 0.21 0.72 0.26 5.00
181 INT292006 Gene_expression of ADSL 8 0.22 2.55 0.26 5.00
182 INT285617 Gene_expression of Etohd1 2 0.04 0.68 0.26 5.00
183 INT195807 Binding of SKAP2 5 0.37 1.99 0.25 5.00
184 INT204021 Transcription of Gsk3b 8 0.57 2.75 0.23 5.00
185 INT346903 Gene_expression of DEFB104B 1 0.58 0.78 0.23 5.00
186 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22 5.00
187 INT327720 Gene_expression of Mcpt4 1 0.49 0.49 0.21 5.00
188 INT346897 Positive_regulation of Atg16l1 1 0.16 0.57 0.19 5.00
189 INT346898 Regulation of Binding of Atg16l1 1 0.09 0.75 0.19 5.00
190 INT327722 Positive_regulation of Localization of Spg21 1 0.05 0.85 0.17 5.00
191 INT346902 Gene_expression of CCL14 1 0.22 0.41 0.17 5.00
192 INT327721 Positive_regulation of Localization of Hspb8 1 0.01 0.55 0.15 5.00
193 INT67181 Positive_regulation of Positive_regulation of SERPINE1 3 0.49 3.02 0.14 5.00
194 INT346908 Negative_regulation of DEFA5 1 0.03 0.41 0.11 5.00
195 INT218859 Negative_regulation of ATP12A 2 0.11 2.86 0.09 5.00
196 INT125009 Gene_expression of HDAC5 3 0.44 0.22 0.09 5.00
197 INT346905 Binding of DEFA5 1 0.02 0.2 0.08 5.00
198 INT266593 Gene_expression of Gdf3 1 0.55 1.44 0.06 5.00
199 INT266603 Gene_expression of Mycs 1 0.53 2.74 0.06 5.00
200 INT346900 Gene_expression of HDAC6 1 0.13 0.17 0.06 5.00
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