D:Hematologic Neoplasms

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Disease Term
Synonyms Hematologic Malignancies, HEMATOLOGIC MALIGNANCY, Hematologic Neoplasm, HEMATOLOGICAL MALIGNANCIES, Hematological Malignancy, Hematological Neoplasm, Hematological Neoplasms, HEMATOPOIETIC MALIGNANCIES, Hematopoietic Malignancy, Hematopoietic Neoplasm, Hematopoietic Neoplasms
Documents 466
Hot Single Events 200
Hot Interactions 12

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hematologic Neoplasms. They are ordered first by their relevance to Hematologic Neoplasms and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 98.12
2 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 97.52
3 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03 96.20
4 INT298632 STAT3 Positive_regulation of MIR21 1 0.03 0.84 0 95.44
5 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03 94.84
6 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03 94.84
7 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 94.00
8 INT298641 PPARA Regulation of STAT3 1 0.23 0.98 0.16 93.76
9 INT298634 Binding of IL6 and STAT3 1 0.04 1.41 0.08 93.40
10 INT310191 Flt3 Positive_regulation of Gene_expression of Id1 1 0.03 0.81 0 91.44
11 INT298633 STAT3 Regulation of MCL1 1 0.04 0.85 0.03 88.16
12 INT144032 STAT3 Regulation of BCL2 2 0.07 0.86 0 88.16
13 INT195199 Gene_expression of IL4 Positive_regulation of Gene_expression of IGHE 1 0.08 1.76 0 77.60
14 INT195198 Gene_expression of IL5 Positive_regulation of Gene_expression of IGHE 1 0.09 1.76 0 77.60
15 INT195197 Gene_expression of IL9 Positive_regulation of Gene_expression of IGHE 1 0.05 1.77 0 77.60
16 INT195196 IL13 Positive_regulation of Gene_expression of IGHE 1 0.06 1.79 0 77.60
17 INT195200 IL10 Positive_regulation of Gene_expression of IGHE 1 0.07 1.78 0 77.60
18 INT302170 PTGER2 Positive_regulation of Gene_expression of BCL2 1 0.04 3.76 0.23 77.44
19 INT302147 PTGER2 Positive_regulation of BAK1 1 0.06 2.08 0.06 77.44
20 INT302177 PTGER2 Positive_regulation of BCL2 1 0.04 2.08 0.06 77.44
21 INT302138 PTGER2 Positive_regulation of Gene_expression of BAK1 1 0.06 2.08 0.06 77.44
22 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 77.28
23 INT278766 HOXA9 Positive_regulation of Gene_expression of PTGS2 1 0.43 1.28 0.35 77.04
24 INT278749 NUP98 Positive_regulation of Gene_expression of PTGS2 1 0.46 1.28 0.35 77.04
25 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48 72.04
26 INT298640 IL6R Positive_regulation of STAT3 1 0.01 0.73 0.03 71.12
27 INT301244 Rb1 Regulation of Hbp1 1 0.03 0.75 0 68.28
28 INT301246 Binding of HMGB1 and Hbp1 1 0.03 0.74 0 68.28
29 INT302152 PTGER2 Positive_regulation of EMR1 1 0.01 2.02 0.07 67.64
30 INT268678 Binding of HDAC2 and NCOR2 1 0.18 2.67 0.07 63.76
31 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 62.96
32 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04 62.96
33 INT277984 Negative_regulation of Epo Positive_regulation of Localization of Ptprc 1 0.02 0.77 0.12 60.80
34 INT268675 Binding of NCOR2 and SIN3A 1 0.27 2.54 0.07 60.32
35 INT277986 Negative_regulation of Epo Positive_regulation of Localization of Cd34 1 0.08 0.77 0.12 60.32
36 INT268673 Binding of NCOR2 and BCOR 1 0.01 2.54 0.07 58.72
37 INT193214 Binding of PTGER2 and PTGER4 2 0.08 2.51 0.18 57.24
38 INT298683 ecs Positive_regulation of Gene_expression of VEGFA 1 0.02 1.41 0.04 55.48
39 INT301241 Mir29a Positive_regulation of Runx1 1 0.00 2.85 0 54.88
40 INT301238 Gene_expression of Mir29a Positive_regulation of Runx1 1 0.00 1.39 0 51.84
41 INT302167 PTGER2 Positive_regulation of EGFR 1 0.10 3.08 0.09 51.52
42 INT302165 PTGER2 Positive_regulation of Localization of EGFR 1 0.06 1.73 0.05 51.52
43 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 50.00
44 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 50.00
45 INT298639 GDE1 Negative_regulation of AKT1 1 0.00 1.14 0.14 50.00
46 INT298638 IL6 Positive_regulation of IL6R 1 0.00 0.9 0.05 50.00
47 INT298635 PPARA Negative_regulation of Localization of ZDHHC2 1 0.01 0.21 0.05 50.00
48 INT298637 ZDHHC2 Negative_regulation of Gene_expression of VEGFA 1 0.01 0.27 0.04 50.00
49 INT298684 ecs Positive_regulation of Gene_expression of KDR 1 0.01 1.2 0 50.00
50 INT277985 Epo Positive_regulation of Epc1 1 0.03 1.36 0.36 48.96
51 INT302166 Positive_regulation of PTGER2 Positive_regulation of EGFR 1 0.07 1.49 0.04 36.52
52 INT234195 HSP90AA1 Regulation of AKT1 1 0.14 0.65 0.03 35.68
53 INT190061 Binding of MLH1 and Mlh1 1 0.01 0.92 0 35.36
54 INT190062 Binding of MLH1 and Msh2 1 0.01 0.91 0 35.36
55 INT192956 Binding of CD2 and KIT 1 0.03 0.62 0 27.36
56 INT192955 Binding of KIT and VCAM1 1 0.05 0.63 0 27.36
57 INT278771 OR51S1 Negative_regulation of Gene_expression of RAP1A 1 0.01 0.22 0 26.72
58 INT195195 IL4 Regulation of Gene_expression of IGHE 1 0.10 0.68 0.04 26.56
59 INT278748 HOXA9 Negative_regulation of Gene_expression of RAP1A 1 0.38 0.44 0 26.32
60 INT278768 NUP98 Negative_regulation of Gene_expression of RAP1A 1 0.41 0.44 0 25.84
61 INT94473 Binding of Cd3e and Trav6-3 2 0.05 0 0.34 20.56
62 INT320824 VEGFA Positive_regulation of DLL4 1 0.40 0.41 0 16.00
63 INT320825 VEGFA Positive_regulation of Gene_expression of DLL4 1 0.40 0.41 0 16.00
64 INT278772 NUP98 Regulation of HOXA9 1 0.42 0 0 14.24
65 INT278755 OR51S1 Regulation of NUP98 1 0.00 0 0 14.24
66 INT278750 HOXA9 Regulation of NUP98 1 0.11 0 0 14.24
67 INT278751 OR51S1 Regulation of HOXA9 1 0.00 0 0 14.24
68 INT278776 NUP98 Regulation of OR51S1 1 0.01 0 0 14.24
69 INT278754 HOXA9 Regulation of OR51S1 1 0.01 0 0 14.24
70 INT278760 EPO Positive_regulation of RAP1A 1 0.13 0.16 0 12.48
71 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 8.28
72 INT302126 PTGER2 Positive_regulation of SRC 1 0.11 1.08 0.03 6.20
73 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
74 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
75 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
76 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
77 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27 5.00
78 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 5.00
79 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
80 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
81 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 5.00
82 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77 5.00
83 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 5.00
84 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 5.00
85 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 5.00
86 INT351076 IK Positive_regulation of Gene_expression of Ucp3 1 0.00 0.8 0.58 5.00
87 INT184100 Il6 Positive_regulation of Stat1 1 0.16 0.68 0.58 5.00
88 INT156668 Gh Positive_regulation of Igf1 5 0.22 2.07 0.57 5.00
89 INT316546 Binding of GH1 and SST 2 0.03 0.55 0.54 5.00
90 INT184111 Epo Positive_regulation of Il7 1 0.06 0.26 0.52 5.00
91 INT184130 Epo Positive_regulation of Stat5a 1 0.31 0.26 0.52 5.00
92 INT184088 Epo Positive_regulation of Il2 1 0.07 0.26 0.52 5.00
93 INT184096 Il7 Positive_regulation of Stat5a 1 0.07 0.26 0.51 5.00
94 INT184132 Il2 Positive_regulation of Stat5a 1 0.09 0.26 0.51 5.00
95 INT184099 Il4 Positive_regulation of Stat4 1 0.13 0.28 0.49 5.00
96 INT184105 Il6 Positive_regulation of Socs3 2 0.42 1.34 0.48 5.00
97 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 5.00
98 INT184117 Il12a Positive_regulation of Stat6 1 0.07 0.28 0.48 5.00
99 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46 5.00
100 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
101 INT184124 Socs3 Regulation of Il6 1 0.13 1.4 0.43 5.00
102 INT241853 Binding of SLC40A1 and HAMP 3 0.41 5.35 0.43 5.00
103 INT184138 Ik Positive_regulation of Stat3 1 0.01 0.29 0.43 5.00
104 INT184135 Il11ra1 Positive_regulation of Stat3 1 0.20 0.3 0.4 5.00
105 INT184092 Il11ra1 Positive_regulation of Jak1 1 0.17 0.3 0.39 5.00
106 INT178217 IFNA1 Regulation of Cxcl10 1 0.01 0.86 0.37 5.00
107 INT178218 IFNA1 Regulation of Tlr7 1 0.04 0.87 0.37 5.00
108 INT184128 Socs3 Negative_regulation of Il6 1 0.12 1.14 0.36 5.00
109 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35 5.00
110 INT184142 Il6 Negative_regulation of Positive_regulation of TNF 1 0.02 0.48 0.35 5.00
111 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
112 INT184095 Il10 Positive_regulation of Socs3 1 0.21 0.49 0.34 5.00
113 INT184082 Binding of Socs3 and Il6 1 0.11 0.49 0.33 5.00
114 INT184084 Jak2 Positive_regulation of Stat1 1 0.33 0.3 0.33 5.00
115 INT184110 Jak1 Positive_regulation of Stat1 1 0.32 0.3 0.33 5.00
116 INT184107 Cish Negative_regulation of Ik 1 0.01 0.1 0.32 5.00
117 INT72445 Binding of AGT and REN 3 0.34 0.88 0.31 5.00
118 INT211308 Binding of Cd4 and Cd8a 3 0.19 0.3 0.31 5.00
119 INT252033 Binding of HLA-DQA2 and KLRD1 1 0.00 0.54 0.29 5.00
120 INT258861 Binding of HLA-DOA and HLA-DRB1 2 0.14 1.88 0.28 5.00
121 INT184141 Il6 Positive_regulation of Gene_expression of IFNA1 1 0.01 0.43 0.28 5.00
122 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 5.00
123 INT302169 PTGER2 Positive_regulation of DYNC1LI1 1 0.02 1.51 0.25 5.00
124 INT190052 Binding of Cdx2 and Ebp 1 0.08 0.82 0.24 5.00
125 INT173120 Binding of PPARA and NR1H4 8 0.09 2.79 0.23 5.00
126 INT190045 Binding of Ebp and Scrib 1 0.10 0.79 0.22 5.00
127 INT291352 Positive_regulation of CXCL12 Positive_regulation of ERBB2 1 0.17 0.88 0.22 5.00
128 INT291348 IL8 Positive_regulation of Phosphorylation of SHC1 1 0.11 1.16 0.2 5.00
129 INT291346 IL8 Positive_regulation of Binding of EGFR and GRB2 1 0.15 1.17 0.2 5.00
130 INT279965 STAT3 Regulation of Transcription of BCL2L1 1 0.10 2.31 0.19 5.00
131 INT258017 Binding of AGT and ANGPT2 3 0.11 2.35 0.19 5.00
132 INT337697 FGF2 Regulation of VEGFA 1 0.03 0.51 0.18 5.00
133 INT201212 FGF2 Regulation of FGFR1 2 0.09 1.01 0.18 5.00
134 INT337698 VEGFA Regulation of FGFR1 1 0.09 0.51 0.18 5.00
135 INT276301 Binding of CCL21 and CXCL13 1 0.04 1.85 0.18 5.00
136 INT184103 Binding of Socs3 and Il11ra1 1 0.12 0 0.17 5.00
137 INT354195 Binding of GH1 and Sstr5 1 0.00 0.1 0.17 5.00
138 INT291354 CXCL12 Positive_regulation of EPHB2 1 0.42 2.02 0.16 5.00
139 INT277990 Binding of Cd3e and Hand1 1 0.01 0.5 0.16 5.00
140 INT184086 Socs5 Negative_regulation of Binding of Jak1 1 0.20 0 0.16 5.00
141 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 5.00
142 INT354114 Binding of CALR and SST 1 0.01 0.1 0.16 5.00
143 INT211311 Trav6-3 Positive_regulation of Gene_expression of Lcp1 1 0.13 0.2 0.15 5.00
144 INT211310 Trav6-3 Positive_regulation of Positive_regulation of Il2 1 0.02 0.2 0.15 5.00
145 INT184098 Binding of Il4 and Socs5 1 0.09 2.05 0.15 5.00
146 INT258906 Binding of HLA-B and HLA-DRB1 1 0.31 1.36 0.15 5.00
147 INT211309 Trav6-3 Positive_regulation of Gene_expression of Klra8 1 0.13 0.2 0.15 5.00
148 INT258909 Binding of HLA-DOA and NDUFA2 1 0.03 1.44 0.15 5.00
149 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14 5.00
150 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
151 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
152 INT302144 CDKN2A Regulation of CDKN1A 1 0.11 0.51 0.14 5.00
153 INT184109 Binding of Gopc and Sh2 1 0.03 0 0.14 5.00
154 INT184104 Binding of Socs3 and Gopc 1 0.10 0 0.14 5.00
155 INT184122 Binding of Socs1 and Sh2 1 0.14 0 0.14 5.00
156 INT252902 PTTG1 Regulation of MMP2 1 0.01 1.5 0.14 5.00
157 INT253009 Igf1 Regulation of PTTG1 1 0.03 0.44 0.13 5.00
158 INT291347 Positive_regulation of TXK Positive_regulation of CXCR4 Positive_regulation of EPHB2 1 0.02 0.61 0.13 5.00
159 INT349222 CSF2 Positive_regulation of Gene_expression of SLC7A7 1 0.17 0.4 0.13 5.00
160 INT184129 Socs2 Negative_regulation of Stat5a 1 0.22 0.05 0.13 5.00
161 INT253015 Egf Regulation of PTTG1 1 0.02 0.44 0.13 5.00
162 INT184091 Socs2 Negative_regulation of Gh 1 0.11 0.05 0.13 5.00
163 INT252901 PTTG1 Regulation of Gene_expression of TSC1 1 0.00 1.61 0.13 5.00
164 INT258016 AGTR1 Positive_regulation of EGFR 1 0.15 1.24 0.13 5.00
165 INT302156 AKT1 Positive_regulation of E2F2 1 0.02 0.88 0.13 5.00
166 INT291349 CXCR4 Positive_regulation of EPHB2 1 0.42 1.87 0.13 5.00
167 INT211313 Binding of Cd3e and Cd8a 1 0.02 0.19 0.13 5.00
168 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
169 INT277988 Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11 5.00
170 INT302161 AKT1 Negative_regulation of CASP9 1 0.03 0.87 0.11 5.00
171 INT354194 Mtpn Negative_regulation of MIR524 1 0.00 0.08 0.11 5.00
172 INT277987 Regulation of Csf3 Positive_regulation of Epc1 1 0.00 0.51 0.11 5.00
173 INT291353 IL8 Positive_regulation of Binding of EGFR 1 0.32 0.52 0.1 5.00
174 INT258014 Binding of ANGPT2 and RASGRP1 1 0.00 1.58 0.1 5.00
175 INT184139 Gh Positive_regulation of Gh Positive_regulation of Stat5b 1 0.06 1.31 0.1 5.00
176 INT191184 Binding of EGFR and GRB2 7 0.35 1.06 0.1 5.00
177 INT302287 Twist1 Positive_regulation of Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
178 INT221068 Cd79a Regulation of Gene_expression of IgG 1 0.01 0.93 0.1 5.00
179 INT221067 Cd79a Regulation of IgG 1 0.01 0.93 0.1 5.00
180 INT302288 Twist1 Positive_regulation of PTGER2 1 0.03 1.16 0.1 5.00
181 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 5.00
182 INT291351 Binding of EGFR and SHC1 1 0.05 0.57 0.1 5.00
183 INT184089 Gh Positive_regulation of Stat5b 1 0.13 1.3 0.1 5.00
184 INT221066 Cd79a Regulation of Gene_expression of Ighm 1 0.01 0.93 0.1 5.00
185 INT291350 IL8 Positive_regulation of Phosphorylation of EGFR 1 0.32 0.52 0.1 5.00
186 INT274449 Binding of Cd4 and H2 2 0.05 1.25 0.1 5.00
187 INT258018 Binding of AGT and RASGRP1 1 0.00 1.59 0.1 5.00
188 INT184140 Socs2 Negative_regulation of Gh Positive_regulation of Stat5b 1 0.10 1.33 0.1 5.00
189 INT291358 Binding of CXCL12 and CXCR7 1 0.20 0.11 0.09 5.00
190 INT276304 PRDM1 Regulation of TSC1 1 0.01 1.29 0.09 5.00
191 INT239559 MSC Regulation of Gene_expression of BDNF 1 0.05 1 0.09 5.00
192 INT276391 Prdm1 Regulation of TSC1 1 0.00 1.29 0.09 5.00
193 INT354120 Binding of IGF2 and IGFBP5 1 0.01 0.45 0.09 5.00
194 INT354124 Binding of IGF2 and IGFBP3 1 0.01 0.45 0.09 5.00
195 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09 5.00
196 INT250661 Binding of EGF and ERBB2 2 0.11 0.82 0.08 5.00
197 INT320789 NRP2 Positive_regulation of Binding of Flt1 and Kdr 1 0.00 0.68 0.08 5.00
198 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08 5.00
199 INT309904 Binding of ERBB2 and TXK 1 0.01 0.23 0.08 5.00
200 INT276375 Binding of Prdm1 and MIR9-1 1 0.12 1.12 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hematologic Neoplasms. They are ordered first by their pain relevance and then by number of times they were reported in Hematologic Neoplasms. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT95616 Gene_expression of Thpo 48 0.78 21.51 5.88 99.98
2 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 99.84
3 INT53871 Gene_expression of Socs1 32 0.71 22.83 6.21 99.80
4 INT176892 Binding of MR1 36 0.32 15.55 2.58 99.74
5 INT117186 Positive_regulation of CXCR4 29 0.69 24.19 6.84 99.72
6 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.54
7 INT91371 Negative_regulation of STAT3 34 0.59 25 4.08 99.48
8 INT217173 Negative_regulation of MIR15B 6 0.42 4.37 0.08 99.42
9 INT27687 Regulation of Cp 20 0.53 9.75 10.8 99.32
10 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 99.26
11 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52 99.24
12 INT298651 Negative_regulation of GDE1 1 0.03 0.87 0 99.20
13 INT201524 Localization of Wnt2 14 0.62 9.24 0.46 99.04
14 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 98.80
15 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 98.80
16 INT117189 Binding of CXCR4 34 0.37 24.27 5.81 98.36
17 INT118916 Gene_expression of SBDS 12 0.53 5.11 1.51 98.32
18 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 98.28
19 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28 98.28
20 INT228104 Gene_expression of Vav1 13 0.77 12.18 0 98.28
21 INT288818 Gene_expression of Rasgrf2 1 0.77 12.76 0 98.28
22 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 98.20
23 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 98.04
24 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 98.04
25 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 98.04
26 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 98.04
27 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 97.84
28 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63 97.84
29 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 97.84
30 INT151611 Binding of SBDS 4 0.33 1.05 0.25 97.76
31 INT151610 Localization of SBDS 1 0.62 0.18 0 97.72
32 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 97.52
33 INT186998 Negative_regulation of Gene_expression of KIT 20 0.43 16.77 0.46 97.52
34 INT14690 Localization of CSF2 124 0.80 85.17 27.26 97.40
35 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 97.36
36 INT192225 Gene_expression of HDAC9 35 0.58 32.82 6.36 97.28
37 INT355200 Regulation of Gene_expression of HDAC9 1 0.14 1.77 0 97.28
38 INT133647 Negative_regulation of HDAC9 149 0.57 106.84 17.9 97.24
39 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 97.24
40 INT103094 Binding of PPARA 308 0.47 177.26 34.75 97.08
41 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 97.08
42 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97 97.08
43 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 97.04
44 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 97.04
45 INT14301 Binding of CSF2 82 0.48 67.95 8.98 96.96
46 INT168975 Binding of Wt1 14 0.43 7.37 0.07 96.88
47 INT205654 Gene_expression of FUS 9 0.32 11.53 0.16 96.88
48 INT148291 Positive_regulation of CSF3 9 0.61 6.37 0.7 96.84
49 INT320831 Positive_regulation of Gene_expression of ZBP1 1 0.01 2.85 0 96.48
50 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 96.48
51 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 96.48
52 INT189580 Positive_regulation of Gene_expression of KDR 9 0.49 5.9 0.05 96.48
53 INT148121 Gene_expression of KRT8 35 0.65 29.07 1.05 96.44
54 INT179856 Gene_expression of Sdc1 4 0.75 3.88 0.03 96.44
55 INT160860 Negative_regulation of Laptm4a 1 0.34 0.54 0 96.40
56 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 96.20
57 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15 96.20
58 INT94161 Negative_regulation of Phosphorylation of CDK1 1 0.41 0.93 0.03 96.20
59 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 96.08
60 INT173159 Localization of PPARA 96 0.74 64.55 10.26 96.08
61 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 96.08
62 INT124375 Gene_expression of Wnt2 67 0.56 38.03 4.67 96.08
63 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 96.08
64 INT163133 Gene_expression of ZBP1 28 0.65 18.59 1.25 96.08
65 INT97902 Gene_expression of AGGF1 17 0.11 13.45 2.51 96.08
66 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 96.08
67 INT18478 Protein_catabolism of CSF2 6 0.88 1.75 1.26 95.88
68 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 95.84
69 INT200734 Phosphorylation of HIST2H3C 6 0.25 3.2 0.78 95.80
70 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 95.80
71 INT301209 Positive_regulation of Mir29a 1 0.11 2.95 0 95.72
72 INT184054 Negative_regulation of Gene_expression of Socs1 7 0.53 9.18 2.22 95.72
73 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 95.64
74 INT94166 Phosphorylation of CDK1 10 0.79 4.75 0.2 95.64
75 INT94160 Positive_regulation of Phosphorylation of CDK1 2 0.49 0.93 0.03 95.64
76 INT205998 Binding of PDAP1 3 0.33 2.66 0.03 95.64
77 INT94714 Protein_catabolism of CSF3R 2 0.43 0.32 0.25 95.48
78 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 95.40
79 INT47540 Binding of Cp 20 0.41 15.54 7.01 94.76
80 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 94.72
81 INT152045 Negative_regulation of Trav6-3 10 0.57 6.42 1.16 94.72
82 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 94.72
83 INT110447 Regulation of Trav6-3 11 0.15 1.93 1.21 94.72
84 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13 94.60
85 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 94.48
86 INT26318 Positive_regulation of CD19 7 0.67 5.61 1.8 94.48
87 INT154491 Phosphorylation of pr 2 0.79 1.94 0.7 94.48
88 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 94.40
89 INT194298 Gene_expression of DHPS 1 0.62 8.84 0.37 94.40
90 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96 94.16
91 INT152037 Regulation of Localization of Csf3 1 0.18 0.74 0.09 94.04
92 INT298667 Negative_regulation of Gene_expression of GDE1 1 0.03 1.02 0 93.84
93 INT200736 Negative_regulation of Gene_expression of HIST2H3C 1 0.13 0.09 0 93.76
94 INT200737 Gene_expression of HIST2H3C 1 0.21 0.09 0 93.76
95 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 93.72
96 INT97900 Negative_regulation of Gene_expression of FGF2 9 0.57 8.37 1.48 93.68
97 INT108723 Negative_regulation of Thpo 5 0.59 3.26 0.51 93.60
98 INT313929 Negative_regulation of Negative_regulation of Thpo 1 0.39 0.54 0.17 93.60
99 INT109329 Negative_regulation of FLT3 7 0.29 6.88 0.38 93.56
100 INT142184 Regulation of TXK 10 0.11 8.25 0.59 93.52
101 INT200738 Gene_expression of HIST2H4A 7 0.18 4.65 0.91 93.48
102 INT200741 Negative_regulation of Gene_expression of HIST2H4A 1 0.11 0.09 0 93.48
103 INT217168 Gene_expression of MIR21 30 0.55 30.86 0.62 93.40
104 INT217156 Positive_regulation of Gene_expression of MIR21 9 0.49 16.04 0.38 93.40
105 INT86437 Binding of IL6 154 0.48 121.22 29.3 93.40
106 INT298661 Gene_expression of GDE1 5 0.04 3.42 0.26 93.28
107 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 93.24
108 INT167546 Positive_regulation of Gene_expression of ecs 6 0.07 5.78 0.92 93.04
109 INT48717 Positive_regulation of Localization of SERPINE1 6 0.66 2.64 0.83 93.04
110 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4 92.96
111 INT1150 Gene_expression of ecs 42 0.59 29.38 7.73 92.60
112 INT190023 Negative_regulation of Mrc1 15 0.25 12.36 0.16 92.40
113 INT32905 Gene_expression of Mrc1 18 0.58 11.07 3.54 92.40
114 INT190025 Positive_regulation of Gene_expression of Mrc1 2 0.22 0.82 0.03 92.40
115 INT301208 Gene_expression of Mir29a 1 0.17 26.18 0 92.32
116 INT301228 Positive_regulation of Gene_expression of Mir29a 1 0.16 13.38 0 92.32
117 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 92.32
118 INT48444 Localization of Csf3 28 0.72 14.85 2.11 92.08
119 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61 92.00
120 INT121818 Binding of STAT3 25 0.47 11.16 3.67 92.00
121 INT320827 Negative_regulation of Gene_expression of THBS1 1 0.03 1.52 0 92.00
122 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 91.92
123 INT190026 Positive_regulation of Gene_expression of Nf1 3 0.53 2.45 0.07 91.64
124 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93 91.64
125 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 91.60
126 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 91.60
127 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45 91.60
128 INT56094 Protein_catabolism of SERPINE1 2 0.61 1.66 0.47 91.56
129 INT289105 Gene_expression of WNT3 4 0.20 2.02 0.37 91.20
130 INT299899 Gene_expression of WNT10A 2 0.06 1.8 0 91.20
131 INT101243 Regulation of STAT3 12 0.62 9.98 1.92 90.96
132 INT213740 Positive_regulation of Epc1 14 0.25 9.8 1.07 90.92
133 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 90.68
134 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 90.68
135 INT279323 Binding of Il2rb 1 0.09 1.86 0 90.64
136 INT284992 Negative_regulation of HDAC8 1 0.21 2.36 0.04 90.40
137 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 90.32
138 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68 90.16
139 INT76751 Negative_regulation of Protein_catabolism of F13A1 7 0.13 5.16 0.79 90.08
140 INT320830 Gene_expression of PRSS27 1 0.65 1.73 0 90.08
141 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 90.04
142 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 90.04
143 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 89.92
144 INT217170 Gene_expression of MIR15A 4 0.75 8.17 0.09 89.84
145 INT217197 Gene_expression of MIR16-1 5 0.45 3.93 0.09 89.84
146 INT129783 Positive_regulation of Gene_expression of KIT 16 0.50 18.12 0.58 89.80
147 INT83531 Gene_expression of KITLG 54 0.65 26 7.07 89.80
148 INT108650 Positive_regulation of Gene_expression of KITLG 2 0.33 2.57 0.41 89.80
149 INT162271 Negative_regulation of Gene_expression of KITLG 4 0.28 2.31 0.07 89.80
150 INT9783 Gene_expression of INSRR 81 0.50 32.99 15.52 89.80
151 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 89.76
152 INT184031 Gene_expression of Cish 14 0.49 9.82 1.86 89.76
153 INT47386 Negative_regulation of CHAT 5 0.29 1.63 2.61 89.72
154 INT124374 Binding of Wnt2 21 0.31 10.16 0.99 89.52
155 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 89.24
156 INT252975 Positive_regulation of Gene_expression of PTTG1 36 0.28 31.96 0.74 89.24
157 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 89.08
158 INT39005 Negative_regulation of FBN1 7 0.42 4.97 2.6 89.08
159 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 89.08
160 INT245089 Localization of CXCL12 8 0.65 10.17 1.28 89.08
161 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 89.08
162 INT129341 Negative_regulation of Gene_expression of Nf1 2 0.43 1.67 0.2 89.08
163 INT190057 Positive_regulation of Negative_regulation of TSC1 2 0.01 1.08 0.03 89.08
164 INT190054 Negative_regulation of Positive_regulation of TSC1 1 0.01 0.83 0.03 89.08
165 INT88694 Gene_expression of WT1 17 0.75 21.88 0.56 88.44
166 INT65659 Positive_regulation of STAT3 132 0.70 69.56 15.95 88.16
167 INT193814 Positive_regulation of Positive_regulation of CXCR4 2 0.38 3.08 0.39 88.16
168 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99 88.12
169 INT87457 Negative_regulation of CD81 3 0.37 1.73 0.42 87.88
170 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 87.84
171 INT217804 Negative_regulation of MITF 19 0.01 19.95 0.57 87.84
172 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 87.76
173 INT173100 Binding of KDR 39 0.39 22.48 0.81 87.64
174 INT192177 Positive_regulation of TMEM37 2 0.30 1.34 0.03 87.60
175 INT310162 Gene_expression of Id1 1 0.10 1.45 0 87.52
176 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68 87.52
177 INT166021 Positive_regulation of MCL1 36 0.67 62.97 1.44 87.52
178 INT72789 Gene_expression of Cpa1 29 0.50 12.36 9.47 87.44
179 INT205657 Negative_regulation of FUS 3 0.21 6.61 0.14 87.04
180 INT234425 Transcription of CEBPA 1 0.38 0.76 0 86.88
181 INT234426 Positive_regulation of Transcription of CEBPA 1 0.27 0.76 0 86.88
182 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49 86.80
183 INT92138 Binding of CDKN2A 28 0.37 25.64 7.47 86.48
184 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 86.32
185 INT234408 Positive_regulation of CEBPA 1 0.27 0.75 0 86.16
186 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 85.76
187 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84 85.76
188 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 85.44
189 INT7298 Gene_expression of NPPA 35 0.70 18.23 4.76 85.44
190 INT228246 Negative_regulation of Gene_expression of Stat3 10 0.58 8.11 0.64 85.28
191 INT301217 Binding of Mir29a 1 0.08 0.78 0 85.28
192 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 84.96
193 INT184018 Negative_regulation of Protein_catabolism of Jak2 1 0.36 1.76 0.08 84.72
194 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37 84.64
195 INT184023 Protein_catabolism of Jak2 1 0.61 1.75 0.08 84.36
196 INT6382 Regulation of Binding of Oprd1 36 0.61 7 26.48 84.28
197 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 84.24
198 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 84.24
199 INT97905 Positive_regulation of FGF2 33 0.70 26.74 5.17 84.24
200 INT176606 Gene_expression of Stat6 9 0.65 6.87 0.77 84.08
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