D:Hematological Disease

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Disease Term
Synonyms Blood Disease, Blood Diseases, Blood Disorder, BLOOD DISORDERS, Blood Dyscrasia, Blood Dyscrasia Syndrome, Disease Blood, Disease Hematologic, Disease Hematological, DISEASE IN THE HAEMATOPOIETIC SYSTEM, Disease In The Hematopoietic System
Documents 767
Hot Single Events 200
Hot Interactions 57

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hematological Disease. They are ordered first by their relevance to Hematological Disease and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT315987 Rhd Positive_regulation of Gene_expression of Igf1 1 0.10 0.47 0.07 100.00
2 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 100.00
3 INT301243 Mir29a Positive_regulation of Mvd 1 0.03 1.66 0 99.96
4 INT300958 IL1B Positive_regulation of Il6 1 0.04 0.25 0.25 99.92
5 INT272439 Binding of ARAF and Prokr2 1 0.01 0.59 0.09 99.84
6 INT267623 IL6 Positive_regulation of Crp 1 0.00 1.6 0.24 99.72
7 INT315535 Binding of ABCB7 and FECH 1 0.28 0.7 0 99.46
8 INT326047 Csf2 Regulation of Epo 1 0.29 0.22 0 98.04
9 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25 97.96
10 INT300859 Il6 Positive_regulation of Ngf 1 0.18 0.3 0.12 97.16
11 INT300857 Il6 Positive_regulation of Bdnf 1 0.09 0.3 0.12 97.16
12 INT215395 Csf2 Positive_regulation of Ppara 1 0.12 1.33 0.32 96.72
13 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 96.48
14 INT152453 Gsk3b Regulation of Nfkb1 1 0.02 1.68 0.36 96.28
15 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61 96.20
16 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07 95.28
17 INT242482 Ciapin1 Positive_regulation of Gene_expression of Bcl2l1 1 0.31 1.05 0.07 95.28
18 INT266682 TRD@ Negative_regulation of TNF 1 0.12 1.55 0 95.08
19 INT88192 IFNG Regulation of Gene_expression of ZAK 1 0.01 0.75 0.36 93.48
20 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 92.68
21 INT315984 Rhd Positive_regulation of Localization of Igf1 1 0.07 0.25 0 92.56
22 INT315985 Rhd Positive_regulation of Igf1 1 0.07 0.25 0 92.56
23 INT223535 Binding of HAND1 and Pax6 1 0.33 0.92 0.13 90.96
24 INT223539 Binding of HAND1 and Szf1 1 0.33 0.92 0.13 90.96
25 INT223530 Binding of Tcf3 and Szf1 1 0.33 0.92 0.13 90.96
26 INT223526 Binding of Pax6 and Tcf3 1 0.33 0.92 0.13 90.96
27 INT300872 Bdnf Positive_regulation of Il6 1 0.09 0.24 0.12 90.08
28 INT300858 Ngf Positive_regulation of Il6 1 0.17 0.24 0.12 90.08
29 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05 89.92
30 INT300853 Ngf Positive_regulation of Fgf2 1 0.14 0.18 0.12 89.84
31 INT300860 Bdnf Positive_regulation of Fgf2 1 0.08 0.18 0.12 89.84
32 INT211571 Pik3r1 Positive_regulation of Gene_expression of Kit 1 0.30 0.3 0 88.44
33 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03 87.88
34 INT242475 Ciapin1 Positive_regulation of Gene_expression of Anxa2 1 0.01 1.13 0.06 87.52
35 INT320794 Binding of VEGFA and Flt4 4 0.08 3.04 0.27 87.16
36 INT249954 Cpa1 Positive_regulation of Nos3 1 0.04 0.36 0.05 86.08
37 INT301237 Mir29a Positive_regulation of Matn1 1 0.02 0.28 0 85.68
38 INT301239 Mir29a Positive_regulation of Mpz 1 0.03 0.28 0 85.68
39 INT301240 Mir29a Positive_regulation of Sumo1 1 0.01 0.28 0 85.68
40 INT101219 TNF Negative_regulation of Gene_expression of EPO 1 0.47 2.8 0.3 85.64
41 INT101220 TNF Negative_regulation of EPO 1 0.48 2.8 0.3 85.64
42 INT320795 Flt1 Negative_regulation of VEGFA 1 0.29 0.29 0.06 85.40
43 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 85.20
44 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26 84.88
45 INT350523 ABL1 Negative_regulation of Pmf1 1 0.01 2.19 0 84.80
46 INT350504 ABL1 Negative_regulation of JAK2 1 0.20 2.18 0 84.80
47 INT70925 Binding of Ifng and Il4 2 0.14 0.9 0.5 84.32
48 INT70924 Binding of Il2 and Il4 1 0.07 0.34 0.36 84.32
49 INT274449 Binding of Cd4 and H2 2 0.05 1.25 0.1 84.32
50 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 84.00
51 INT87025 ZAK Positive_regulation of Gene_expression of IL6 2 0.11 1.59 1.02 83.36
52 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 83.12
53 INT300869 Ntrk2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.16 0.08 82.40
54 INT87023 ZAK Positive_regulation of Gene_expression of IL36RN 1 0.03 0.62 0.36 82.16
55 INT300877 Negative_regulation of AKT1 Negative_regulation of Il6 1 0.04 0.16 0 82.08
56 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 81.72
57 INT215394 Binding of Csf2 and Positive_regulation of Ppara 1 0.12 0.49 0.14 80.52
58 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 78.80
59 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 78.80
60 INT264326 IL-17 Positive_regulation of Gene_expression of Il6 1 0.13 0.83 0.43 78.60
61 INT245299 Ccl5 Positive_regulation of Localization of IL8 1 0.11 2.87 0.66 78.32
62 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66 77.20
63 INT200822 Akt1 Regulation of Jak2 1 0.25 1.48 0.03 76.92
64 INT223523 Positive_regulation of Hmga1 Positive_regulation of Erv4 1 0.21 0.95 0 76.76
65 INT128221 Binding of IL6ST and Il6 2 0.00 0.73 0.17 76.56
66 INT77142 Binding of IFNG and IL4 2 0.03 1.16 0.95 76.24
67 INT300876 Bdnf Positive_regulation of NTRK2 1 0.01 0.27 0.15 75.96
68 INT300875 Ngf Positive_regulation of NTRK2 1 0.01 0.27 0.15 75.96
69 INT132610 Bdnf Positive_regulation of Ntrk2 4 0.46 1.09 0.93 75.32
70 INT300861 Ngf Positive_regulation of Ntrk2 1 0.29 0.27 0.15 75.32
71 INT11684 Binding of CSF2 and IL3 6 0.36 3.3 0.72 75.00
72 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2 74.36
73 INT200810 Jak2 Positive_regulation of Src 1 0.29 1.46 0.03 73.24
74 INT267592 IL6 Positive_regulation of Localization of MUC1 1 0.00 1.24 0.07 73.16
75 INT200813 Jak2 Positive_regulation of Akt1 1 0.26 1.46 0.03 73.08
76 INT264324 Olr614 Regulation of IL-17 1 0.02 2.3 1.03 72.28
77 INT300855 Il1 Regulation of Il6 1 0.01 0.81 0.3 71.32
78 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2 69.68
79 INT253073 Il4 Positive_regulation of Hand2 1 0.10 0.59 0.31 69.28
80 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24 68.28
81 INT200814 Epo Positive_regulation of Lyn 1 0.36 1.42 0.03 66.48
82 INT320788 VEGFA Positive_regulation of Binding of Flt1 and Kdr 1 0.15 0.68 0.08 65.88
83 INT320789 NRP2 Positive_regulation of Binding of Flt1 and Kdr 1 0.00 0.68 0.08 65.40
84 INT200811 Epo Positive_regulation of Akt1 2 0.30 1.77 0.09 65.36
85 INT87024 Positive_regulation of ZAK Positive_regulation of Localization of IFNG 2 0.05 0.81 0.58 64.72
86 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 64.44
87 INT320785 Binding of Flt1 and Kdr 1 0.15 0.67 0.08 64.44
88 INT200820 Epo Positive_regulation of Src 1 0.25 1.41 0.03 64.16
89 INT272418 CGA Regulation of Gene_expression of PROK1 1 0.01 0.34 0 63.60
90 INT245571 Runx1 Positive_regulation of Tbx15 Positive_regulation of Ntrk1 1 0.02 0.91 0.25 63.44
91 INT326049 Csf2 Negative_regulation of Epo 1 0.46 0.25 0 62.76
92 INT213262 IL6 Positive_regulation of CYP19A1 1 0.11 1.63 0.03 62.44
93 INT245567 Tbx15 Positive_regulation of Ntrk1 1 0.02 0.9 0.24 62.28
94 INT99577 Binding of KITLG and Kit 3 0.34 2.33 1.11 60.00
95 INT245558 Runx3 Regulation of Ngfr 1 0.06 1 0.53 57.68
96 INT118416 Gata2 Positive_regulation of Transcription of Tac2 1 0.27 0.2 0.07 56.64
97 INT105435 TNF Positive_regulation of IL6 5 0.25 4.45 0.83 56.48
98 INT271874 IL10 Negative_regulation of TNF 1 0.07 0.78 0.5 56.36
99 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22 56.24
100 INT350702 Rc3h1 Positive_regulation of Protein_catabolism of Icos 1 0.35 1.56 0.18 56.00
101 INT213261 TNF Positive_regulation of CRP 1 0.24 1.59 0.06 55.16
102 INT300867 Negative_regulation of Mapk1 Negative_regulation of Gene_expression of Il6 1 0.02 0.42 0.08 53.80
103 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34 53.04
104 INT264332 Olr614 Negative_regulation of Regulation of Igh-6 1 0.01 1.04 0.48 52.92
105 INT253076 Prok2 Positive_regulation of Ik 1 0.02 0.49 0.41 52.32
106 INT305204 Pbrgcsf1 Positive_regulation of Gene_expression of Epo 1 0.27 0.6 0.27 52.24
107 INT245561 Gene_expression of Runx1 Positive_regulation of Gene_expression of Tbx15 1 0.02 0.8 0.25 52.24
108 INT245553 Runx1 Positive_regulation of Gene_expression of Ntrk1 2 0.45 1.41 0.52 51.84
109 INT245557 Runx1 Positive_regulation of Gene_expression of Tbx15 1 0.02 0.75 0.25 51.84
110 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 51.64
111 INT271873 IL10 Regulation of Gene_expression of IK 1 0.00 0.81 0.47 51.00
112 INT271872 IL10 Regulation of IK 1 0.00 0.81 0.47 51.00
113 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32 49.52
114 INT352087 Binding of ADAM11 and TLR4 1 0.05 1.09 0.04 49.04
115 INT352076 Binding of TLR4 and Positive_regulation of ADAM11 1 0.06 1.09 0.04 49.04
116 INT88191 Binding of NCOR2 and ZAK 1 0.00 0.17 0.21 48.88
117 INT200812 Akt1 Positive_regulation of Negative_regulation of Hck 1 0.25 1.02 0 46.40
118 INT200817 Akt1 Positive_regulation of Negative_regulation of Fgr 1 0.25 1.02 0 46.40
119 INT200818 Akt1 Positive_regulation of Negative_regulation of Lyn 1 0.25 1.02 0 46.40
120 INT308805 Positive_regulation of Pld1 Positive_regulation of TNF 1 0.05 0.74 0.24 44.00
121 INT350695 Mir101a Positive_regulation of Protein_catabolism of Icos 1 0.05 0.8 0.1 43.96
122 INT245554 Tbx15 Positive_regulation of Gene_expression of Ntrk1 1 0.02 0.65 0.29 43.68
123 INT308804 Pld1 Positive_regulation of TNF 1 0.05 2.42 0.99 43.60
124 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06 43.44
125 INT305203 Epo Positive_regulation of Gene_expression of Neurog1 1 0.06 0.4 0.21 42.20
126 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 41.76
127 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 40.40
128 INT300863 Bdnf Positive_regulation of Mapk1 1 0.02 0.11 0 40.40
129 INT300864 Ngf Positive_regulation of Mapk14 2 0.60 1.38 1.32 40.08
130 INT300862 Bdnf Positive_regulation of Mapk14 1 0.02 0.11 0 40.08
131 INT300854 Ngf Positive_regulation of Positive_regulation of Il6 1 0.18 0.06 0 39.20
132 INT300856 Bdnf Positive_regulation of Positive_regulation of Il6 1 0.09 0.06 0 39.20
133 INT350694 Uts2r Negative_regulation of Negative_regulation of Rc3h1 1 0.05 0.79 0.1 38.40
134 INT300870 Bdnf Positive_regulation of Gene_expression of Il6 1 0.10 0 0.05 36.64
135 INT234142 Mat1a Regulation of Tk1 1 0.06 0.07 0 35.76
136 INT234143 Mat1a Regulation of Gene_expression of Tk1 1 0.06 0.07 0 35.76
137 INT211573 Positive_regulation of Binding of Dbp and Stip1 1 0.00 0.38 0 34.88
138 INT211578 Binding of Dbp and Stip1 1 0.00 0.38 0 34.88
139 INT189493 Tnf Positive_regulation of Localization of Darc 1 0.00 0.53 0.37 31.60
140 INT189492 Ifng Positive_regulation of Localization of Darc 1 0.00 0.53 0.34 31.16
141 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22 30.72
142 INT189489 Il1b Positive_regulation of Localization of Darc 1 0.00 0.53 0.34 30.60
143 INT305208 Pbrgcsf1 Positive_regulation of Localization of VEGFA 1 0.05 0.22 0.04 28.72
144 INT170995 Binding of IFNA1 and Positive_regulation of Localization of CCL5 1 0.03 0.34 0.19 27.72
145 INT249955 Cpa1 Positive_regulation of Nos2 1 0.02 0.33 0.06 25.68
146 INT303949 LEPR Positive_regulation of SOAT1 1 0.01 0.22 0.28 25.36
147 INT303948 LEPR Positive_regulation of PIK3CG 1 0.02 0.22 0.28 25.36
148 INT300865 Ngf Positive_regulation of Gene_expression of Il6 1 0.17 0 0 24.68
149 INT249958 Cpa1 Positive_regulation of NOS1 1 0.00 0.32 0.06 22.64
150 INT173613 BMP2 Positive_regulation of INCENP 1 0.00 0.28 0.03 22.08
151 INT173612 FGFR1 Positive_regulation of INCENP 1 0.00 0.28 0.03 21.68
152 INT305205 Binding of Epo and Pbrgcsf1 1 0.14 0.23 0.07 19.64
153 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 0.17 0.18 0 18.60
154 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0 18.60
155 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0 14.36
156 INT338828 Binding of Trf and TMPRSS6 1 0.05 0.1 0 11.20
157 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
158 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
159 INT121651 Binding of CXCL12 and CXCR4 13 0.48 17.61 3.52 5.00
160 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 5.00
161 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
162 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6 5.00
163 INT122163 Binding of TNF and TNFRSF1B 6 0.44 6.06 2.41 5.00
164 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86 5.00
165 INT194863 Binding of IL1R1 and IL1RN 5 0.09 2.23 1.64 5.00
166 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
167 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33 5.00
168 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29 5.00
169 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27 5.00
170 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2 5.00
171 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18 5.00
172 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16 5.00
173 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11 5.00
174 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
175 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1 5.00
176 INT82024 Binding of Ngfr and Ngf 2 0.33 1.48 1.05 5.00
177 INT181434 Binding of Ccr2 and Ccl2 1 0.27 6.06 1.04 5.00
178 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
179 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02 5.00
180 INT291377 Binding of CX3CR1 and Cx3cl1 2 0.36 3.57 1.02 5.00
181 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01 5.00
182 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91 5.00
183 INT181437 Binding of Ccr7 and Ccl21b 1 0.01 2.23 0.87 5.00
184 INT181452 Binding of Ccl19 and Ccl21b 1 0.02 2.22 0.86 5.00
185 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
186 INT245564 Runx3 Negative_regulation of Ntrk2 3 0.61 1.61 0.79 5.00
187 INT194644 Tlr4 Positive_regulation of TNF 6 0.58 2.42 0.76 5.00
188 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 5.00
189 INT248271 IL6 Regulation of Gene_expression of Crp 3 0.27 1.7 0.73 5.00
190 INT289333 Binding of Ngfr and Rtn4r 1 0.03 2.35 0.72 5.00
191 INT289332 Binding of Ngfr and Lingo1 1 0.04 2.36 0.72 5.00
192 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71 5.00
193 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 5.00
194 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67 5.00
195 INT289357 Ngfr Positive_regulation of Akt1 1 0.03 3.1 0.66 5.00
196 INT207111 F2 Positive_regulation of Pawr 2 0.07 1.38 0.64 5.00
197 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64 5.00
198 INT279398 Binding of IL1RN and Il1rn 1 0.00 0.51 0.63 5.00
199 INT248172 Epo Regulation of Cysltr1 1 0.01 0.74 0.63 5.00
200 INT264334 Binding of IL-17 and Positive_regulation of Localization of Csf3 1 0.13 1.64 0.63 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hematological Disease. They are ordered first by their pain relevance and then by number of times they were reported in Hematological Disease. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 100.00
2 INT8803 Gene_expression of IL3 32 0.78 21.06 6.01 100.00
3 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 100.00
4 INT149485 Regulation of Gene_expression of C3 5 0.60 3.39 0.75 100.00
5 INT56290 Negative_regulation of Gene_expression of Il6 79 0.59 47.98 31.07 99.92
6 INT94826 Positive_regulation of HBS1L 13 0.40 4.62 0.61 99.88
7 INT223496 Positive_regulation of Gene_expression of Szf1 1 0.40 2.79 0.36 99.84
8 INT223499 Gene_expression of Szf1 1 0.54 0.92 0.12 99.84
9 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 99.82
10 INT153410 Negative_regulation of Jak2 5 0.59 10.71 3.98 99.82
11 INT79671 Positive_regulation of Gene_expression of Pbrgcsf1 8 0.32 4.25 0.57 99.80
12 INT14556 Positive_regulation of Igf1 105 0.69 52.21 24.04 99.78
13 INT8775 Binding of IGHE 167 0.48 102.61 23.54 99.78
14 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 99.70
15 INT76752 Negative_regulation of TOP2B 8 0.42 6.2 0.14 99.68
16 INT22450 Gene_expression of GPI 31 0.58 18.77 6.71 99.66
17 INT58756 Binding of GPI 10 0.48 7.17 3 99.66
18 INT128794 Negative_regulation of Gene_expression of HBB 1 0.59 5.98 0.06 99.64
19 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.62
20 INT134040 Regulation of Jak2 3 0.41 1.07 0.92 99.62
21 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 99.56
22 INT4587 Negative_regulation of Serping1 32 0.47 19.11 5.92 99.56
23 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 99.54
24 INT15007 Gene_expression of Pbrgcsf1 31 0.49 17.82 6.99 99.54
25 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 99.52
26 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 99.52
27 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 99.52
28 INT9655 Regulation of Il6 98 0.62 70.92 31.95 99.48
29 INT115264 Binding of FECH 9 0.41 7.93 1.1 99.46
30 INT315605 Binding of ABCB7 1 0.33 1.84 0 99.46
31 INT149861 Gene_expression of CD52 14 0.75 9.35 0.47 99.44
32 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 99.36
33 INT149015 Gene_expression of Tph2 20 0.78 9.45 10.4 99.36
34 INT105266 Localization of Tcf3 3 0.32 1.08 0.59 99.28
35 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42 99.28
36 INT295096 Localization of Pou1f1 1 0.79 1.48 0 99.28
37 INT205196 Gene_expression of Lpar2 18 0.74 12.19 3.49 99.16
38 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 99.16
39 INT71885 Protein_catabolism of Nfkb1 8 0.53 5.34 3.69 99.12
40 INT288 Positive_regulation of Sct 88 0.70 32.83 24.5 99.12
41 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 99.08
42 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 99.08
43 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 99.08
44 INT105543 Gene_expression of DNTT 11 0.65 4.63 1 99.08
45 INT25381 Localization of Csf2 62 0.76 47.48 9.03 99.04
46 INT48444 Localization of Csf3 28 0.72 14.85 2.11 99.04
47 INT11686 Regulation of IL3 15 0.45 8.69 2.54 99.00
48 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 99.00
49 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 98.98
50 INT146563 Gene_expression of PROK2 15 0.75 4.12 0.61 98.96
51 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 98.96
52 INT352108 Positive_regulation of ADAM11 1 0.49 35.19 1.59 98.96
53 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43 98.96
54 INT158573 Negative_regulation of Jak3 3 0.43 8.2 3.99 98.92
55 INT328808 Negative_regulation of Jak1 1 0.42 7.01 3.64 98.92
56 INT205912 Negative_regulation of Gene_expression of Jak2 8 0.42 5.1 1.04 98.92
57 INT83798 Negative_regulation of Gene_expression of Bcl2l1 28 0.58 20.26 4.21 98.92
58 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 98.84
59 INT101105 Positive_regulation of FUT1 62 0.30 55.96 9.28 98.82
60 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 98.62
61 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 98.56
62 INT8801 Gene_expression of Csf3 71 0.74 45.6 10.83 98.52
63 INT50971 Gene_expression of Ntrk1 180 0.75 73.52 62.28 98.50
64 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 98.48
65 INT116642 Negative_regulation of Gsk3b 13 0.57 7.16 3.83 98.48
66 INT25382 Binding of Il2 16 0.37 11.69 2.32 98.48
67 INT201346 Negative_regulation of Gene_expression of Cd19 3 0.32 2.1 0.05 98.46
68 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 98.36
69 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 98.36
70 INT113161 Gene_expression of Jak2 50 0.77 42.52 4.76 98.24
71 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 98.24
72 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 98.24
73 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 98.24
74 INT247975 Gene_expression of Alm 2 0.07 1.31 0 98.22
75 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 98.22
76 INT62031 Gene_expression of Cd19 27 0.65 10.39 0.93 98.22
77 INT237075 Gene_expression of Spn 5 0.42 5.18 0.56 98.22
78 INT11313 Positive_regulation of Il6 526 0.70 331.27 201.59 98.20
79 INT125586 Gene_expression of Stmn1 13 0.75 8.28 0.42 98.16
80 INT235362 Gene_expression of SNORA73A 8 0.75 4.09 0 98.16
81 INT39060 Gene_expression of Mpz 45 0.77 21.55 4.3 98.14
82 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 98.08
83 INT216735 Gene_expression of Matn1 2 0.65 1.68 0.72 98.04
84 INT121752 Gene_expression of IL11 54 0.62 18.05 7.16 97.96
85 INT171851 Gene_expression of Sumo1 13 0.30 10.7 0.89 97.86
86 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 97.80
87 INT65055 Negative_regulation of Nfkb1 83 0.58 44.85 34.94 97.76
88 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 97.72
89 INT301208 Gene_expression of Mir29a 1 0.17 26.18 0 97.68
90 INT249099 Binding of SAI1 3 0.05 0.81 0.03 97.68
91 INT332930 Regulation of Binding of SAI1 1 0.01 0.42 0 97.68
92 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 97.56
93 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 97.52
94 INT192423 Positive_regulation of TARM1 5 0.34 10.77 0.51 97.44
95 INT176445 Protein_catabolism of Gopc 23 0.76 7.57 0.75 97.44
96 INT21869 Negative_regulation of Otc 16 0.58 8.43 3.67 97.40
97 INT4436 Gene_expression of ABCB7 7 0.65 9.26 0.93 97.36
98 INT140223 Regulation of Ccl2 15 0.45 13.1 5.41 97.36
99 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 97.32
100 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 97.32
101 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34 97.32
102 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 97.24
103 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04 97.20
104 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 97.16
105 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 97.16
106 INT114462 Gene_expression of Scx 5 0.76 3.68 0.17 97.16
107 INT202420 Transcription of Jak2 1 0.56 0.91 0 97.16
108 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 97.16
109 INT181393 Regulation of Ccl25 2 0.29 1.09 1.04 97.16
110 INT181338 Regulation of Cxcl13 1 0.10 0.52 0.69 97.16
111 INT181366 Regulation of Ccl21b 1 0.01 0.52 0.69 97.16
112 INT114464 Positive_regulation of Gene_expression of Scx 1 0.43 0.87 0 97.16
113 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 97.12
114 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 97.12
115 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81 97.12
116 INT178029 Gene_expression of Epo 25 0.76 14.98 1.46 97.00
117 INT118407 Transcription of Tac2 5 0.60 0.94 0.4 96.92
118 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48 96.88
119 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09 96.88
120 INT11936 Positive_regulation of Positive_regulation of Il6 34 0.50 26.85 10.59 96.84
121 INT54662 Positive_regulation of Positive_regulation of Il1 21 0.43 19.33 7.14 96.84
122 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 96.76
123 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31 96.76
124 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 96.72
125 INT200200 Positive_regulation of Negative_regulation of Igf1 3 0.47 2.33 0.22 96.72
126 INT181382 Gene_expression of Ccl25 2 0.74 10.94 6.56 96.68
127 INT181347 Gene_expression of Cxcl13 9 0.63 9.08 3.75 96.68
128 INT181368 Gene_expression of Ccl21b 1 0.03 3.48 2.01 96.68
129 INT17326 Binding of Plg 14 0.43 11.72 1.94 96.64
130 INT181385 Regulation of Ccl7 1 0.35 0.95 0.9 96.64
131 INT756 Gene_expression of C3 138 0.75 100.6 19.2 96.60
132 INT248415 Binding of Tph2 9 0.44 3.88 0.34 96.48
133 INT142184 Regulation of TXK 10 0.11 8.25 0.59 96.48
134 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 96.44
135 INT1876 Positive_regulation of HLA-B 82 0.69 52.16 21.08 96.44
136 INT25386 Positive_regulation of Cd3e 30 0.62 13.91 3.41 96.40
137 INT181339 Regulation of Ccl8 3 0.40 1.55 1.02 96.40
138 INT268379 Gene_expression of ARAF 22 0.16 9.34 1.07 96.24
139 INT272427 Regulation of Gene_expression of ARAF 2 0.02 1.33 0.12 96.24
140 INT144993 Gene_expression of Epor 4 0.75 5.7 1.61 96.20
141 INT255663 Binding of Flt1 11 0.32 6.92 1.64 96.20
142 INT242464 Positive_regulation of Ciapin1 1 0.61 3.32 0.05 96.16
143 INT199383 Gene_expression of Prokr2 8 0.59 7.37 5.21 96.12
144 INT66823 Positive_regulation of PIGA 2 0.49 2.83 0 96.00
145 INT66822 Positive_regulation of Positive_regulation of PIGA 1 0.49 1 0 96.00
146 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 95.96
147 INT110184 Binding of HMI 9 0.28 5.52 2.24 95.88
148 INT174492 Positive_regulation of Gene_expression of Cd3e 8 0.39 5.08 0.77 95.84
149 INT242065 Positive_regulation of Cflar 4 0.12 2.65 0.14 95.80
150 INT135578 Gene_expression of Prokr1 22 0.70 11.71 8.31 95.76
151 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 95.68
152 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76 95.64
153 INT61949 Regulation of Nos2 74 0.58 34.08 16.7 95.60
154 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 95.60
155 INT72757 Negative_regulation of Negative_regulation of Nos2 8 0.42 4.23 2.68 95.60
156 INT174100 Gene_expression of YWHAE 14 0.31 12.42 0.08 95.52
157 INT284484 Positive_regulation of Gene_expression of YWHAE 3 0.23 3.4 0.08 95.52
158 INT283811 Gene_expression of Csta 1 0.74 9.08 0.05 95.48
159 INT248001 Positive_regulation of Gene_expression of SNORA73A 1 0.49 2.51 0 95.40
160 INT8112 Regulation of EPO 38 0.58 22.04 2.76 95.40
161 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71 95.24
162 INT83991 Regulation of Nos3 25 0.44 9.89 4.06 95.24
163 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 95.12
164 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 95.08
165 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 95.08
166 INT9660 Regulation of TNF 363 0.62 312.94 139.99 95.08
167 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 95.08
168 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 94.88
169 INT22434 Gene_expression of Ads1 10 0.75 9.16 1.4 94.76
170 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18 94.68
171 INT242467 Positive_regulation of Gene_expression of Ciapin1 1 0.70 27.67 0.26 94.64
172 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 94.64
173 INT140175 Regulation of Kit 23 0.62 8.59 1.79 94.64
174 INT6481 Binding of TNF 624 0.48 510.2 214.82 94.64
175 INT319954 Localization of MCAM 1 0.65 0.09 0.09 94.64
176 INT188047 Positive_regulation of Wnt2 51 0.58 31.41 2.94 94.52
177 INT70614 Gene_expression of FAS 118 0.75 112.33 19.01 94.52
178 INT83531 Gene_expression of KITLG 54 0.65 26 7.07 94.52
179 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.40
180 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 94.32
181 INT9210 Regulation of IL6 166 0.62 125.61 49.95 94.28
182 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 94.20
183 INT181129 Positive_regulation of Araf 8 0.21 4.3 0.79 94.20
184 INT16321 Gene_expression of Cd3e 111 0.72 49.9 14.21 94.08
185 INT91152 Regulation of Pecam1 4 0.30 4.14 0.42 94.04
186 INT91151 Regulation of Flt4 1 0.06 1.96 0.15 94.04
187 INT125587 Positive_regulation of Gene_expression of Stmn1 9 0.67 4.2 0.08 94.00
188 INT7534 Gene_expression of Ifng 193 0.78 111.02 68.6 93.88
189 INT102659 Gene_expression of CSF3 32 0.77 21.93 2.39 93.80
190 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 93.72
191 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25 93.68
192 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22 93.68
193 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 93.68
194 INT173624 Negative_regulation of Positive_regulation of SELP 1 0.04 0.38 0 93.68
195 INT235291 Protein_catabolism of Cpa1 1 0.31 0.46 0 93.68
196 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47 93.44
197 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 93.28
198 INT108481 Positive_regulation of CCL19 4 0.44 15.22 3.77 93.24
199 INT126514 Positive_regulation of CCR7 16 0.43 16.21 2.79 93.24
200 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 93.20
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