D:Hemifacial Microsomia

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Asymmetries Facial, ASYMMETRY FACIAL, Facial Asymmetries, Facial Asymmetry, Hemifacial Microsomia Disorder
Documents 172
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hemifacial Microsomia. They are ordered first by their relevance to Hemifacial Microsomia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 13.44
2 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36 5.00
3 INT239081 Binding of GH1 and MAS1 1 0.03 1.41 0.15 5.00
4 INT204246 ETFA Regulation of CD68 1 0.37 1.05 0.04 5.00
5 INT204247 S100B Regulation of CD68 1 0.03 1.05 0.04 5.00
6 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0 5.00
7 INT265964 TNNI2 Regulation of CA2 1 0.22 0.09 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hemifacial Microsomia. They are ordered first by their pain relevance and then by number of times they were reported in Hemifacial Microsomia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT168919 Regulation of Regulation of Ihh 1 0.40 0.43 0.07 94.48
2 INT140984 Regulation of Ihh 5 0.54 2.81 0.56 94.08
3 INT102698 Binding of ACCS 54 0.42 66.73 9.06 87.80
4 INT35548 Regulation of Mme 9 0.45 10.62 2.97 83.68
5 INT38674 Regulation of KRT20 32 0.44 19 2.15 83.68
6 INT162148 Regulation of Cd79a 1 0.00 0.75 0.13 83.68
7 INT168916 Positive_regulation of Gene_expression of Ndst1 1 0.50 0.35 0.08 62.64
8 INT168917 Gene_expression of Ndst1 1 0.68 0.35 0.08 62.64
9 INT148341 Gene_expression of MAS1 9 0.65 4.19 0.68 62.24
10 INT131488 Binding of MAS1 9 0.36 8.49 1.01 60.68
11 INT105021 Binding of GOPC 187 0.40 60.39 20.38 59.52
12 INT239085 Binding of KAT2B 1 0.18 2.04 0.09 59.52
13 INT239082 Binding of BCAM 1 0.03 2.03 0.09 59.52
14 INT15610 Localization of GOPC 223 0.65 68.26 28.7 53.92
15 INT239084 Localization of KAT2B 4 0.73 3.08 0.36 53.92
16 INT239086 Localization of BCAM 2 0.54 2.32 0.09 53.92
17 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 51.12
18 INT168918 Negative_regulation of Ndst1 1 0.43 0.43 0.17 49.20
19 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 44.96
20 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 35.08
21 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 33.84
22 INT1020 Negative_regulation of BCHE 109 0.59 44.86 16.4 31.76
23 INT961 Positive_regulation of ATRX 3 0.53 1.99 0.36 27.72
24 INT100601 Localization of PRNP 17 0.66 13.61 0.71 22.88
25 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 16.84
26 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 16.44
27 INT246641 Gene_expression of YWHAQ 5 0.58 3 0.22 12.28
28 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 11.16
29 INT167203 Binding of PRNP 25 0.48 20.09 1.84 5.76
30 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
31 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
32 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 5.00
33 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
34 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
35 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
36 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 5.00
37 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
38 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
39 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 5.00
40 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66 5.00
41 INT11937 Localization of Il6 228 0.81 139.83 64.39 5.00
42 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 5.00
43 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
44 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 5.00
45 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 5.00
46 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
47 INT6979 Positive_regulation of CA2 206 0.67 50.79 44.97 5.00
48 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
49 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
50 INT9655 Regulation of Il6 98 0.62 70.92 31.95 5.00
51 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 5.00
52 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
53 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 5.00
54 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
55 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
56 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
57 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
58 INT11938 Positive_regulation of Localization of Il6 61 0.70 35.72 18.25 5.00
59 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
60 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 5.00
61 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 5.00
62 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
63 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
64 INT65057 Regulation of Nfkb1 28 0.47 16.48 11.62 5.00
65 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
66 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 5.00
67 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 5.00
68 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 5.00
69 INT10019 Binding of CD8A 57 0.36 31.49 10.08 5.00
70 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
71 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 5.00
72 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98 5.00
73 INT25585 Positive_regulation of DNAH8 39 0.70 17.96 7.85 5.00
74 INT74520 Positive_regulation of CD68 30 0.61 31.68 7.59 5.00
75 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 5.00
76 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94 5.00
77 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
78 INT62336 Positive_regulation of Hdc 38 0.70 14.45 5.51 5.00
79 INT3165 Gene_expression of LYZ 25 0.65 16.72 5.16 5.00
80 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 5.00
81 INT49375 Regulation of Localization of Il6 16 0.62 4.54 5.08 5.00
82 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9 5.00
83 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
84 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 5.00
85 INT149332 Gene_expression of CD163 19 0.75 13.63 3.65 5.00
86 INT19491 Gene_expression of CD19 44 0.75 28.8 3.47 5.00
87 INT78284 Positive_regulation of PTPRC 40 0.49 27.17 3.45 5.00
88 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 5.00
89 INT17511 Negative_regulation of PRTN3 19 0.41 12 3.3 5.00
90 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 5.00
91 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
92 INT82913 Regulation of Ppara 15 0.61 10.66 3.03 5.00
93 INT239083 Binding of PPY 9 0.32 7.59 2.9 5.00
94 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 5.00
95 INT24895 Positive_regulation of LYZ 25 0.70 17.92 2.64 5.00
96 INT98607 Regulation of Regulation of TNF 8 0.44 6.95 2.56 5.00
97 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 5.00
98 INT2544 Localization of PTH 39 0.81 30.55 2.22 5.00
99 INT105824 Regulation of Casq1 4 0.07 2.66 2.1 5.00
100 INT83896 Gene_expression of CD1A 19 0.68 15.58 2.1 5.00
101 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 5.00
102 INT20388 Binding of LYZ 8 0.39 5.65 1.93 5.00
103 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 5.00
104 INT114490 Gene_expression of PDLIM7 17 0.78 11.35 1.42 5.00
105 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21 5.00
106 INT119187 Gene_expression of HLA-DRB5 5 0.02 4.47 1.18 5.00
107 INT85621 Regulation of PRNP 16 0.60 8.7 1.15 5.00
108 INT160576 Gene_expression of Psgb1 3 0.35 1.63 1.08 5.00
109 INT181973 Positive_regulation of MAS1 8 0.49 7.64 1.07 5.00
110 INT183933 Binding of CD68 8 0.31 8.74 1.06 5.00
111 INT90240 Gene_expression of MYOG 19 0.75 10 1.06 5.00
112 INT198406 Localization of C2 5 0.65 1.42 1.01 5.00
113 INT161591 Positive_regulation of CD163 5 0.48 3.9 0.98 5.00
114 INT959 Regulation of ATRX 5 0.47 5.04 0.89 5.00
115 INT68228 Positive_regulation of TNFRSF8 5 0.56 6.26 0.84 5.00
116 INT125627 Gene_expression of TTF1 11 0.78 12.68 0.78 5.00
117 INT167381 Localization of DES 4 0.73 4.15 0.77 5.00
118 INT204254 Localization of KIT 8 0.73 6.78 0.61 5.00
119 INT91209 Binding of VIM 15 0.36 12.02 0.53 5.00
120 INT107118 Positive_regulation of ALK 4 0.49 3.64 0.52 5.00
121 INT163993 Gene_expression of Hnf1a 2 0.65 1.38 0.49 5.00
122 INT204258 Binding of NSMCE1 4 0.36 6.41 0.42 5.00
123 INT153260 Gene_expression of CD22 19 0.70 8.35 0.39 5.00
124 INT117096 Gene_expression of Wnt4 2 0.67 4.68 0.38 5.00
125 INT204941 Protein_catabolism of Timp2 1 0.03 0.35 0.32 5.00
126 INT2659 Positive_regulation of Psgb1 2 0.40 3.25 0.3 5.00
127 INT962 Gene_expression of ATRX 2 0.59 1.72 0.27 5.00
128 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 5.00
129 INT201570 Gene_expression of CR2 11 0.48 14.21 0.22 5.00
130 INT68056 Gene_expression of NSMCE1 2 0.14 0.49 0.2 5.00
131 INT281732 Binding of LTK 1 0.00 1.03 0.19 5.00
132 INT134223 Localization of CD99 4 0.73 4.42 0.16 5.00
133 INT196691 Positive_regulation of Positive_regulation of DNAH8 2 0.10 1.23 0.13 5.00
134 INT166811 Regulation of Casq1 3 0.04 1.18 0.1 5.00
135 INT265969 Regulation of TNNI2 1 0.45 1.35 0.09 5.00
136 INT265966 Regulation of MYH3 1 0.44 1.35 0.09 5.00
137 INT350956 Binding of Psgb1 1 0.03 1.64 0.08 5.00
138 INT350958 Positive_regulation of PSG9 1 0.07 1.56 0.07 5.00
139 INT204256 Gene_expression of HCLS1 1 0.03 5.24 0.07 5.00
140 INT281731 Positive_regulation of LTK 1 0.01 1.27 0.05 5.00
141 INT204255 Localization of MYOG 1 0.18 1.82 0.03 5.00
142 INT204938 Positive_regulation of Casq1 1 0.08 0.17 0.03 5.00
143 INT205576 Positive_regulation of Hnf1a 2 0.49 1.1 0 5.00
144 INT205587 Negative_regulation of Cyp17a1 1 0.28 0.24 0 5.00
145 INT265972 Positive_regulation of Gene_expression of ATRX 1 0.38 1.72 0 5.00
146 INT204253 Binding of TTF1 1 0.16 1.71 0 5.00
147 INT265970 Binding of TNNI2 1 0.37 0.2 0 5.00
148 INT265971 Gene_expression of MYH3 1 0.66 1.2 0 5.00
149 INT205583 Gene_expression of Hnf1b 1 0.59 2.09 0 5.00
150 INT204259 Binding of CD163 3 0.24 3.29 0 5.00
151 INT205579 Positive_regulation of Gene_expression of Hnf1b 1 0.44 2.1 0 5.00
152 INT265967 Gene_expression of TNNI2 1 0.67 1.39 0 5.00
153 INT205582 Positive_regulation of Hnf1b 1 0.44 1.05 0 5.00
154 INT205585 Regulation of Wnt4 1 0.45 0.7 0 5.00
155 INT205578 Negative_regulation of Wnt4 1 0.43 1.69 0 5.00
156 INT350957 Binding of Psg27 1 0.04 0.93 0 5.00
157 INT204252 Positive_regulation of NSMCE1 3 0.04 1.92 0 5.00
158 INT205581 Regulation of Negative_regulation of Wnt4 1 0.27 0.7 0 5.00
159 INT205577 Positive_regulation of Gene_expression of Hnf1a 1 0.49 1.1 0 5.00
160 INT265968 Gene_expression of TNNT3 1 0.65 1.39 0 5.00
161 INT204257 Gene_expression of RTL1 3 0.08 3.09 0 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox