D:Hemorrhagic Diathesis

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Disease Term
Synonyms Diatheses Hemorrhagic, Diathesis Hemorrhagic, Disorder Hemorrhagic, Disorders Hemorrhagic, Haemorrhagic Condition, HAEMORRHAGIC CONDITIONS, Haemorrhagic Diathesis, HAEMORRHAGIC DISEASE, HAEMORRHAGIC DISEASES, Haemorrhagic Disorder, Haemorrhagic Disorders
Documents 131
Hot Single Events 21
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hemorrhagic Diathesis. They are ordered first by their relevance to Hemorrhagic Diathesis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT197646 DPH1 Negative_regulation of Localization of BGLAP 1 0.01 0.26 0.04 85.92
2 INT197645 DPH1 Positive_regulation of SHBG 1 0.02 0.06 0.14 63.32
3 INT301292 Negative_regulation of Clec5a Negative_regulation of TNF 1 0.05 1.04 0.27 48.08
4 INT172465 Binding of Rab27a and Rab27b 2 0.41 1.71 0.27 17.04
5 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28 5.00
6 INT301285 Binding of Tyrobp and Clec5a 1 0.32 1.63 0.49 5.00
7 INT301277 Il6 Positive_regulation of Positive_regulation of Clec5a 1 0.16 0.37 0.29 5.00
8 INT301287 Positive_regulation of Clec5a Positive_regulation of Gene_expression of Il6 1 0.14 0.58 0.29 5.00
9 INT301289 Positive_regulation of Clec5a Positive_regulation of Gene_expression of Atp6v0d2 1 0.02 1.01 0.28 5.00
10 INT301276 Il6 Positive_regulation of Gene_expression of Tnfrsf11a 1 0.06 0.37 0.26 5.00
11 INT301280 Il6 Positive_regulation of Gene_expression of Acp5 1 0.04 0.37 0.26 5.00
12 INT301291 Il6 Positive_regulation of Gene_expression of TNF 1 0.01 0.37 0.26 5.00
13 INT301279 Tnfsf11 Regulation of Gene_expression of Mmp9 1 0.13 0.34 0.21 5.00
14 INT301281 Tnfsf11 Regulation of Gene_expression of Clec5a 1 0.22 0.34 0.21 5.00
15 INT301290 Tnfsf11 Positive_regulation of Nfatc1 1 0.15 0.65 0.2 5.00
16 INT301282 Tnfsf11 Positive_regulation of Traf6 1 0.10 0.65 0.2 5.00
17 INT197647 DPH1 Negative_regulation of VDR 1 0.02 0.58 0.18 5.00
18 INT301278 Nfatc1 Regulation of Acp5 1 0.05 0.19 0.15 5.00
19 INT301283 Nfatc1 Regulation of Ctsk 1 0.06 0.19 0.13 5.00
20 INT301284 Tnfsf11 Positive_regulation of Localization of Nfatc1 1 0.16 0.32 0.11 5.00
21 INT301288 Clec5a Regulation of Nfatc1 1 0.21 0.25 0.1 5.00
22 INT215245 Binding of Myo1f and Chd7 1 0.00 0.64 0.1 5.00
23 INT197644 NR1I2 Negative_regulation of Positive_regulation of CYP3A 1 0.02 0.47 0.08 5.00
24 INT197650 NR1I2 Negative_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08 5.00
25 INT197652 NR1I2 Positive_regulation of Positive_regulation of CYP2A 1 0.02 0.47 0.08 5.00
26 INT197649 NR1I2 Positive_regulation of VDR 1 0.15 0.54 0.07 5.00
27 INT197648 ESRRB Positive_regulation of VDR 1 0.03 0.54 0.07 5.00
28 INT296749 PTGER2 Positive_regulation of PTGER1 1 0.25 0 0.05 5.00
29 INT319111 Binding of Yy1 and Sap30 1 0.01 0 0.04 5.00
30 INT215240 Binding of Myo1f and Racgap1 1 0.01 0.77 0.04 5.00
31 INT215244 Binding of Racgap1 and Mlph 1 0.04 0.76 0.04 5.00
32 INT319094 Binding of polymerase and RNPC3 1 0.00 0.13 0 5.00
33 INT215243 Binding of Rab3a and Noc2l 1 0.00 0.26 0 5.00
34 INT215246 Binding of Rab27a and Rph3a 1 0.07 0.26 0 5.00
35 INT197651 TNF Regulation of PTH 1 0.05 1.67 0 5.00
36 INT215239 Binding of Rab27a and Sytl4 1 0.26 0.26 0 5.00
37 INT215241 Binding of Rab3a and Rph3a 1 0.00 0.26 0 5.00
38 INT215242 Binding of Rab27a and Noc2l 1 0.07 0.26 0 5.00
39 INT215238 Binding of Rab3a and Sytl4 1 0.01 0.26 0 5.00
40 INT197643 TNF Regulation of VDR 1 0.04 1.67 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hemorrhagic Diathesis. They are ordered first by their pain relevance and then by number of times they were reported in Hemorrhagic Diathesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT46476 Binding of DPH1 2 0.28 0.49 0.37 99.76
2 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 99.16
3 INT2919 Negative_regulation of F8 47 0.59 23.48 5.1 99.16
4 INT10890 Binding of F8 11 0.36 7.27 1.15 98.60
5 INT10888 Binding of Vwf 32 0.46 22.87 5.21 97.96
6 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 96.92
7 INT2129 Positive_regulation of F2 83 0.70 58.95 12.63 96.92
8 INT1038 Negative_regulation of F2 26 0.58 15.12 6.75 95.36
9 INT96845 Positive_regulation of Regulation of Serpinc1 1 0.18 1.78 1.22 95.08
10 INT57494 Positive_regulation of Positive_regulation of Serpinc1 3 0.26 1.67 1.19 95.08
11 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98 95.04
12 INT39634 Regulation of Gene_expression of F2 4 0.22 1.72 1.31 95.04
13 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26 95.04
14 INT14396 Regulation of Serpinc1 5 0.19 3.16 1.16 95.04
15 INT96844 Regulation of Positive_regulation of Serpinc1 1 0.10 0.89 0.61 95.04
16 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 94.48
17 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43 91.80
18 INT2805 Negative_regulation of C7 1 0.26 0.73 0.11 87.12
19 INT68260 Localization of BGLAP 34 0.78 16.04 4.63 85.92
20 INT104032 Negative_regulation of Localization of BGLAP 4 0.33 2.22 0.04 85.92
21 INT3880 Negative_regulation of Serping1 54 0.58 37.19 4.75 82.28
22 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 79.60
23 INT4047 Binding of F13A1 105 0.43 66.54 11.81 79.08
24 INT23278 Negative_regulation of Binding of F13A1 6 0.39 3.54 1.37 79.08
25 INT90899 Gene_expression of Rab27a 49 0.78 26.71 0.74 78.20
26 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 76.00
27 INT301263 Gene_expression of Clec5a 22 0.77 14.64 5.18 74.12
28 INT228951 Gene_expression of HIST1H4PS1 3 0.05 1.29 0.03 72.08
29 INT228950 Positive_regulation of Gene_expression of HIST1H4PS1 1 0.03 0.77 0.03 72.08
30 INT44741 Negative_regulation of F13B 1 0.03 0.64 0.1 67.60
31 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 66.60
32 INT27018 Gene_expression of PTGER1 68 0.75 31.76 20.12 65.44
33 INT34720 Positive_regulation of SHBG 58 0.69 32.4 3.83 62.60
34 INT119827 Gene_expression of PTPN11 31 0.75 24.21 1.22 60.56
35 INT326331 Gene_expression of ZC3H7B 1 0.01 1.27 0 60.56
36 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 60.36
37 INT241303 Localization of PTPN11 8 0.77 10.23 0.06 57.28
38 INT326330 Localization of ZC3H7B 1 0.01 1.25 0 57.28
39 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 56.64
40 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 55.16
41 INT172438 Gene_expression of Rab27b 8 0.77 10.95 0.27 52.40
42 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34 49.76
43 INT301261 Negative_regulation of Clec5a 3 0.58 1.68 0.66 48.08
44 INT2228 Protein_catabolism of SUPT7L 1 0.64 0.09 0.1 47.36
45 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 46.68
46 INT123701 Negative_regulation of VDR 61 0.59 48.94 9.67 46.00
47 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 45.44
48 INT11937 Localization of Il6 228 0.81 139.83 64.39 44.44
49 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 38.36
50 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12 38.36
51 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 37.44
52 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 30.96
53 INT197662 Negative_regulation of Positive_regulation of SHBG 5 0.39 3.54 0.52 27.68
54 INT215225 Regulation of Localization of Rab3d 1 0.29 0.38 0 27.60
55 INT12135 Gene_expression of PLEK 62 0.75 34.13 12.47 25.00
56 INT18143 Gene_expression of Tbxas1 9 0.56 5.89 2.39 25.00
57 INT215235 Localization of Rab3d 1 0.52 0.38 0 24.96
58 INT215234 Binding of Rab27b 1 0.37 0.54 0.14 17.04
59 INT215233 Positive_regulation of Gene_expression of Rab3d 1 0.45 0.38 0 15.92
60 INT215231 Gene_expression of Rab3d 1 0.50 0.38 0 15.92
61 INT172442 Binding of Rab27a 3 0.37 1.5 0.21 15.84
62 INT301262 Negative_regulation of Gene_expression of Clec5a 1 0.43 3.01 1.02 15.80
63 INT23010 Positive_regulation of CYP19A1 28 0.58 24.18 5.37 12.64
64 INT171105 Positive_regulation of Positive_regulation of CYP19A1 5 0.39 4.02 0.58 12.64
65 INT110569 Gene_expression of XDH 31 0.75 18.35 1.34 8.52
66 INT209435 Regulation of Tyrobp 2 0.40 1.55 0.37 7.48
67 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
68 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
69 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
70 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
71 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
72 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
73 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
74 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
75 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
76 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
77 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
78 INT118381 Gene_expression of Il17a 405 0.76 306.97 112.06 5.00
79 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
80 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
81 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
82 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
83 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
84 INT6585 Positive_regulation of Insrr 110 0.52 40.67 89.9 5.00
85 INT48408 Gene_expression of ICAM1 494 0.78 340.08 88.6 5.00
86 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
87 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
88 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 5.00
89 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 5.00
90 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
91 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
92 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 5.00
93 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
94 INT55671 Gene_expression of Ik 151 0.27 80.1 48.49 5.00
95 INT145266 Gene_expression of IL17A 154 0.75 109.83 45.33 5.00
96 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
97 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 5.00
98 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
99 INT62827 Positive_regulation of ICAM1 184 0.70 180.95 36.28 5.00
100 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
101 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 5.00
102 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 5.00
103 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
104 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 5.00
105 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 5.00
106 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 5.00
107 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 5.00
108 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
109 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
110 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
111 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 5.00
112 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 5.00
113 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
114 INT15796 Regulation of IL2 66 0.61 25.43 20.62 5.00
115 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
116 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 5.00
117 INT49103 Positive_regulation of Vcam1 71 0.69 59.52 19.85 5.00
118 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
119 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 5.00
120 INT35487 Localization of PTGER2 103 0.46 51.24 17.45 5.00
121 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 5.00
122 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 5.00
123 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
124 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
125 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
126 INT3623 Negative_regulation of CTSB 49 0.55 27.39 13.52 5.00
127 INT73594 Positive_regulation of Gene_expression of ISYNA1 61 0.55 31.35 13.45 5.00
128 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
129 INT150851 Positive_regulation of Cxcl1 45 0.57 20.83 11.88 5.00
130 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 5.00
131 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
132 INT119700 Gene_expression of VDR 88 0.75 65.33 11.5 5.00
133 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47 5.00
134 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
135 INT1762 Negative_regulation of PTGER2 64 0.43 28.21 11.27 5.00
136 INT56448 Regulation of ICAM1 52 0.60 55.1 10.96 5.00
137 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 5.00
138 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81 5.00
139 INT16449 Binding of IGHG3 67 0.48 39.55 10.59 5.00
140 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53 5.00
141 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 5.00
142 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 5.00
143 INT76573 Negative_regulation of Vcam1 26 0.58 24.36 9.84 5.00
144 INT63341 Negative_regulation of ICAM1 42 0.59 30.45 9.5 5.00
145 INT59465 Negative_regulation of ISYNA1 41 0.49 21.9 9.46 5.00
146 INT73497 Regulation of IL10 33 0.45 22.6 9.19 5.00
147 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01 5.00
148 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
149 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 5.00
150 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 5.00
151 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 5.00
152 INT39457 Positive_regulation of SOAT1 32 0.67 22.8 8.28 5.00
153 INT12334 Positive_regulation of CYP3A 34 0.70 6.77 7.85 5.00
154 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84 5.00
155 INT81399 Regulation of Vcam1 24 0.46 23.53 7.68 5.00
156 INT18524 Regulation of Gene_expression of IFNA1 37 0.44 18.79 7.62 5.00
157 INT73508 Negative_regulation of Gene_expression of ISYNA1 32 0.51 19.67 7.57 5.00
158 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45 5.00
159 INT153794 Gene_expression of Ctsk 51 0.77 24.99 7.28 5.00
160 INT35584 Binding of ACLY 22 0.35 31.78 7.17 5.00
161 INT17041 Gene_expression of PER1 24 0.66 5.31 7.12 5.00
162 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 5.00
163 INT66925 Positive_regulation of Gene_expression of Ik 22 0.15 10.47 6.4 5.00
164 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 5.00
165 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 5.00
166 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
167 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 5.00
168 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 5.00
169 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63 5.00
170 INT107619 Gene_expression of PTGER3 42 0.75 15 5.61 5.00
171 INT186063 Phosphorylation of SOAT1 29 0.28 11.77 5.34 5.00
172 INT171562 Regulation of IL4 19 0.36 12.12 5.33 5.00
173 INT80712 Gene_expression of PTGER4 21 0.65 13.08 5.03 5.00
174 INT11493 Positive_regulation of KLK1 21 0.67 9.22 5 5.00
175 INT59464 Regulation of ISYNA1 21 0.43 12.15 4.63 5.00
176 INT35765 Gene_expression of TXNRD1 47 0.56 9.16 4.43 5.00
177 INT97131 Positive_regulation of CD14 25 0.67 12.03 4.21 5.00
178 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21 5.00
179 INT88278 Binding of Kit 33 0.37 24.45 4.13 5.00
180 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07 5.00
181 INT134590 Localization of ADA 7 0.65 8.43 3.96 5.00
182 INT54701 Localization of Ptafr 19 0.49 18.68 3.82 5.00
183 INT63121 Binding of APC 29 0.41 23.02 3.8 5.00
184 INT111532 Gene_expression of Nfatc1 15 0.75 5.27 3.73 5.00
185 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73 5.00
186 INT67724 Regulation of Gene_expression of ISYNA1 14 0.51 5.99 3.62 5.00
187 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 5.00
188 INT148892 Binding of HPS1 13 0.37 19.21 3.35 5.00
189 INT171998 Binding of DMD 58 0.47 38.13 3.35 5.00
190 INT14397 Gene_expression of Serpinc1 27 0.46 14.54 3.32 5.00
191 INT61259 Negative_regulation of Itgam 16 0.47 11.11 3.27 5.00
192 INT175262 Binding of SH2B2 18 0.36 22.85 3.18 5.00
193 INT37590 Regulation of COL7A1 15 0.54 9.4 3.12 5.00
194 INT107011 Positive_regulation of NR1I2 14 0.49 8.85 3.11 5.00
195 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 5.00
196 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99 5.00
197 INT301272 Positive_regulation of Clec5a 1 0.69 6.17 2.92 5.00
198 INT234717 Regulation of Cxcl1 10 0.41 6.14 2.9 5.00
199 INT10893 Binding of VWF 27 0.47 25.02 2.82 5.00
200 INT170305 Regulation of Gene_expression of Mmp9 11 0.33 5.7 2.8 5.00
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