D:Hemosiderosis

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Disease Term
Synonyms HAEMOSIDEROSIS, Hemosideroses
Documents 58
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hemosiderosis. They are ordered first by their relevance to Hemosiderosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT191816 Binding of ETFA and TGM2 1 0.01 0.66 0 14.96
2 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
3 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
4 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
5 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
6 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
7 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
8 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
9 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
10 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
11 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
12 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
13 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
14 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
15 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
16 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
17 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
18 INT289293 Binding of CD59 and Cd33 1 0.02 1.06 0 5.00
19 INT289301 Binding of CD59 and Cd24a 1 0.02 1.06 0 5.00
20 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
21 INT318132 Binding of ATRX and HBE1 1 0.00 1.47 0 5.00
22 INT289296 Binding of CD59 and C6 1 0.02 0.5 0 5.00
23 INT289295 Binding of CD59 and Fcgr3 1 0.01 1.06 0 5.00
24 INT289297 Negative_regulation of Binding of CD59 and C6 1 0.02 0.51 0 5.00
25 INT289300 Binding of CD59 and Fut4 1 0.01 1.06 0 5.00
26 INT289294 Binding of CD59 and Atp6ap1 1 0.10 0.51 0 5.00
27 INT289299 Binding of CD59 and Cd14 1 0.02 1.06 0 5.00
28 INT289298 Negative_regulation of Binding of CD59 and Atp6ap1 1 0.12 0.51 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hemosiderosis. They are ordered first by their pain relevance and then by number of times they were reported in Hemosiderosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT103638 Negative_regulation of MEFV 7 0.39 5.88 0.54 99.54
2 INT150395 Binding of MEFV 55 0.44 31.18 3.42 98.38
3 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 93.12
4 INT79464 Binding of HBA2 2 0.47 1.75 0.09 92.96
5 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 88.28
6 INT104316 Positive_regulation of ETFA 2 0.17 2.4 0.12 83.88
7 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 75.20
8 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68 75.00
9 INT73500 Regulation of IL13 12 0.36 10.37 3.53 69.92
10 INT171562 Regulation of IL4 19 0.36 12.12 5.33 69.44
11 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 68.48
12 INT166835 Regulation of HBB 1 0.02 1.08 0.08 65.76
13 INT8775 Binding of IGHE 167 0.48 102.61 23.54 57.12
14 INT43907 Binding of CD79A 28 0.48 28.11 3.04 57.12
15 INT22597 Positive_regulation of TF 43 0.68 27.27 5.17 50.00
16 INT14572 Binding of INS 205 0.48 175.43 13.38 35.16
17 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 34.16
18 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 26.88
19 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 26.88
20 INT191826 Binding of ETFA 1 0.03 0.66 0 14.96
21 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 12.64
22 INT204348 Gene_expression of PPARGC1A 10 0.75 2.73 0.19 12.64
23 INT226175 Regulation of thd 8 0.14 6.8 1.42 10.32
24 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
25 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
26 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
27 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
28 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
29 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
30 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
31 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 5.00
32 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
33 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 5.00
34 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
35 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
36 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
37 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
38 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
39 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 5.00
40 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
41 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
42 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
43 INT6364 Gene_expression of Edn1 123 0.78 73.76 28.43 5.00
44 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
45 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
46 INT20044 Negative_regulation of Gpi1 50 0.59 29.96 26 5.00
47 INT4781 Gene_expression of TH 68 0.73 26.92 24.01 5.00
48 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
49 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 5.00
50 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
51 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
52 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
53 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
54 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
55 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 5.00
56 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
57 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
58 INT12081 Localization of TGFB1 64 0.81 35.4 17.47 5.00
59 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 5.00
60 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 5.00
61 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
62 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
63 INT171666 Regulation of GOPC 117 0.39 40.41 15.47 5.00
64 INT75502 Positive_regulation of CDKN1A 123 0.68 70.75 14.74 5.00
65 INT37430 Gene_expression of Gpi1 61 0.63 54.63 13.87 5.00
66 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
67 INT18012 Gene_expression of EPO 169 0.78 108.36 13.75 5.00
68 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
69 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 5.00
70 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
71 INT102272 Regulation of TH1L 41 0.44 30.89 11.63 5.00
72 INT192967 Gene_expression of Hp 14 0.43 8.06 11.01 5.00
73 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
74 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
75 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 5.00
76 INT69306 Negative_regulation of TH1L 28 0.57 24.81 9.74 5.00
77 INT57162 Positive_regulation of Gene_expression of CDKN1A 64 0.68 35.3 9.69 5.00
78 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 5.00
79 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 5.00
80 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 5.00
81 INT19185 Negative_regulation of Cd4 80 0.51 61.32 8.51 5.00
82 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 5.00
83 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 5.00
84 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
85 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
86 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
87 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
88 INT5490 Binding of CA2 52 0.36 9.73 5.53 5.00
89 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
90 INT103518 Negative_regulation of SCN2A 17 0.57 8.4 5.4 5.00
91 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 5.00
92 INT89104 Binding of TGFB1 29 0.44 13.67 5.12 5.00
93 INT120073 Positive_regulation of Itk 34 0.44 23.45 5.09 5.00
94 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
95 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37 5.00
96 INT6507 Binding of C5 23 0.48 15.35 3.91 5.00
97 INT69904 Binding of Hc 11 0.35 7.79 3.69 5.00
98 INT9256 Gene_expression of SELPLG 30 0.75 16.44 3.66 5.00
99 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6 5.00
100 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
101 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
102 INT23220 Positive_regulation of FOXG1 10 0.43 2.86 3.49 5.00
103 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
104 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31 5.00
105 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 5.00
106 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 5.00
107 INT78297 Gene_expression of CD59 31 0.72 24.11 3.18 5.00
108 INT38013 Gene_expression of Casr 30 0.73 6.03 3.09 5.00
109 INT226178 Gene_expression of thd 14 0.23 8.29 2.92 5.00
110 INT74508 Gene_expression of Gypa 7 0.75 2.15 2.89 5.00
111 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 5.00
112 INT155160 Binding of C3 20 0.47 7.77 2.61 5.00
113 INT182034 Binding of Gpi1 10 0.39 8.76 2.59 5.00
114 INT12485 Binding of DNAH8 17 0.48 4.24 2.54 5.00
115 INT18969 Gene_expression of HLA-DQA1 29 0.65 12.19 2.54 5.00
116 INT32421 Gene_expression of FCER2 19 0.73 17.23 2.53 5.00
117 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 5.00
118 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 5.00
119 INT102036 Positive_regulation of Dre 12 0.59 4.41 2.4 5.00
120 INT35359 Negative_regulation of LCT 23 0.59 9.13 2.29 5.00
121 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 5.00
122 INT68865 Gene_expression of ACOX1 13 0.52 5.49 2.09 5.00
123 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99 5.00
124 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98 5.00
125 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 5.00
126 INT91550 Gene_expression of PPM1D 7 0.10 0.68 1.81 5.00
127 INT29777 Negative_regulation of CD59 16 0.42 14.88 1.56 5.00
128 INT55479 Localization of Epo 13 0.81 6.1 1.53 5.00
129 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 5.00
130 INT27762 Positive_regulation of Gene_expression of EPO 18 0.70 17.67 1.45 5.00
131 INT182035 Positive_regulation of Gene_expression of Gpi1 5 0.36 4.95 1.4 5.00
132 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39 5.00
133 INT273128 Protein_catabolism of Hp 3 0.47 2.2 1.39 5.00
134 INT179169 Transcription of IL13 11 0.15 4.22 1.37 5.00
135 INT29898 Negative_regulation of C6orf25 16 0.29 9.58 1.33 5.00
136 INT100275 Gene_expression of TBL1XR1 19 0.25 6.99 1.33 5.00
137 INT120075 Gene_expression of Itk 11 0.43 6.39 1.27 5.00
138 INT57689 Localization of CD59 7 0.78 4.51 1.17 5.00
139 INT9243 Gene_expression of FOXG1 14 0.53 7.52 1.02 5.00
140 INT15040 Gene_expression of NKX2-1 8 0.65 3.95 1.02 5.00
141 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1 5.00
142 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97 5.00
143 INT102353 Positive_regulation of HLA-DQA2 6 0.06 4.07 0.82 5.00
144 INT169706 Positive_regulation of Gene_expression of Itk 2 0.32 2.08 0.81 5.00
145 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66 5.00
146 INT274725 Regulation of TBL1XR1 5 0.11 2.08 0.64 5.00
147 INT190229 Gene_expression of Cd55 7 0.64 5 0.64 5.00
148 INT191825 Regulation of Positive_regulation of CD8A 3 0.12 2.5 0.62 5.00
149 INT161807 Phosphorylation of ROS1 10 0.43 4.86 0.62 5.00
150 INT122737 Gene_expression of Daf2 6 0.69 2.11 0.61 5.00
151 INT36201 Gene_expression of ETFA 8 0.66 9.18 0.58 5.00
152 INT181965 Negative_regulation of Gene_expression of Gpi1 3 0.07 2.83 0.51 5.00
153 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 5.00
154 INT227043 Negative_regulation of Dre 2 0.19 1.13 0.49 5.00
155 INT277912 Positive_regulation of Gene_expression of CD59 2 0.19 2.76 0.49 5.00
156 INT274724 Positive_regulation of TBL1XR1 5 0.12 2.74 0.45 5.00
157 INT128793 Gene_expression of HBB 16 0.78 10.69 0.42 5.00
158 INT216873 Binding of TBL1XR1 3 0.36 4.44 0.4 5.00
159 INT186453 Gene_expression of TAB1 6 0.65 4.83 0.35 5.00
160 INT186450 Negative_regulation of SFTPB 17 0.58 10.94 0.31 5.00
161 INT290576 Positive_regulation of NPTX2 1 0.06 3.32 0.31 5.00
162 INT317746 Positive_regulation of Gene_expression of FCER2 2 0.01 4.09 0.3 5.00
163 INT125804 Localization of Pth 9 0.69 3.93 0.29 5.00
164 INT191823 Positive_regulation of TGM2 2 0.30 1.95 0.25 5.00
165 INT100277 Positive_regulation of Gene_expression of TBL1XR1 5 0.19 1.9 0.25 5.00
166 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22 5.00
167 INT204363 Gene_expression of VIS1 6 0.19 2.49 0.21 5.00
168 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21 5.00
169 INT239883 Transcription of SFTPC 3 0.69 1.11 0.18 5.00
170 INT192842 Binding of Hspa5 3 0.33 1.48 0.16 5.00
171 INT231230 Localization of SFTPC 2 0.68 2.06 0.16 5.00
172 INT284968 Positive_regulation of CDA 2 0.05 0.34 0.15 5.00
173 INT156610 Negative_regulation of HBB 2 0.37 1.25 0.15 5.00
174 INT146139 Gene_expression of ETV4 11 0.12 8.43 0.11 5.00
175 INT41890 Positive_regulation of Gene_expression of FOXG1 2 0.32 1.04 0.09 5.00
176 INT74442 Binding of ATRX 2 0.41 3.2 0.09 5.00
177 INT320983 Negative_regulation of Localization of Pth 2 0.38 1.17 0.09 5.00
178 INT208515 Regulation of Gene_expression of Gpi1 2 0.11 2.51 0.09 5.00
179 INT331623 Negative_regulation of Binding of TGFB1 1 0.02 1.02 0.08 5.00
180 INT128794 Negative_regulation of Gene_expression of HBB 1 0.59 5.98 0.06 5.00
181 INT331613 Regulation of Positive_regulation of Itk 1 0.02 0.87 0.06 5.00
182 INT300743 Regulation of MS4A2 1 0.00 0.62 0.06 5.00
183 INT331615 Binding of Igbp1 1 0.00 0.95 0.05 5.00
184 INT274745 Localization of TAB1 2 0.45 0.74 0.04 5.00
185 INT191542 Binding of ABCA3 1 0.22 1.61 0.03 5.00
186 INT258134 Gene_expression of NPTX2 2 0.40 0.65 0 5.00
187 INT289270 Positive_regulation of Gene_expression of Cd55 1 0.24 0.6 0 5.00
188 INT259001 Localization of Cd55 2 0.35 1.1 0 5.00
189 INT300746 Gene_expression of MS4A2 1 0.01 0.25 0 5.00
190 INT300748 Negative_regulation of Negative_regulation of IGHE 1 0.38 0.55 0 5.00
191 INT289283 Negative_regulation of Gene_expression of CD59 2 0.18 0.9 0 5.00
192 INT207239 Binding of HBE1 2 0.20 1.53 0 5.00
193 INT318137 Negative_regulation of PMCH 1 0.02 0.96 0 5.00
194 INT228302 Transcription of 16S 3 0.67 0.08 0 5.00
195 INT300749 Binding of MS4A2 1 0.00 0.38 0 5.00
196 INT289273 Negative_regulation of Gene_expression of Cd55 1 0.20 0.53 0 5.00
197 INT179299 Binding of TGM2 3 0.24 1.02 0 5.00
198 INT331624 Transcription of SFTPB 1 0.03 0.48 0 5.00
199 INT289275 Positive_regulation of Gene_expression of Piga 1 0.49 0.85 0 5.00
200 INT274747 Regulation of COX1 1 0.26 0.1 0 5.00
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