D:Hepatic Porphyrias

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pChart

Disease Term
Synonyms Hepatic Porphyria, PORPHYRIA HEPATIC
Documents 57
Hot Single Events 33
Hot Interactions 0

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hepatic Porphyrias. They are ordered first by their pain relevance and then by number of times they were reported in Hepatic Porphyrias. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT158690 Negative_regulation of 3.8-1.4 2 0.07 2.77 0.13 99.72
2 INT15509 Negative_regulation of HMBS 14 0.58 13.13 2.78 99.72
3 INT50290 Binding of Cpox 29 0.27 17.19 8.01 99.72
4 INT158692 Negative_regulation of Gene_expression of HMBS 1 0.25 0.67 0.09 99.72
5 INT158691 Negative_regulation of BTF3P4 1 0.03 0.59 0.08 99.72
6 INT74178 Gene_expression of HMBS 24 0.76 9.62 1.36 99.44
7 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.40
8 INT49441 Negative_regulation of Cpox 494 0.59 303.22 177.46 99.06
9 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.06
10 INT89 Positive_regulation of Gast 187 0.70 80.49 42.07 97.84
11 INT24800 Negative_regulation of AMPD1 44 0.59 21.19 6.76 97.84
12 INT90 Localization of Gast 400 0.81 137.67 113 97.84
13 INT1189 Gene_expression of AMPD1 7 0.59 4.1 0.9 97.84
14 INT17934 Localization of MLN 16 0.80 2.83 2.24 97.68
15 INT102747 Gene_expression of Hmbs 17 0.78 10.53 1.34 97.12
16 INT3322 Positive_regulation of Gene_expression of ALAS2 4 0.43 3.25 0 96.68
17 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 96.68
18 INT40216 Positive_regulation of Alas1 11 0.65 6.08 1.8 95.36
19 INT35990 Negative_regulation of Sds 8 0.49 4.47 4.96 95.32
20 INT70616 Positive_regulation of LOC689539 1 0.17 0.6 0.43 95.08
21 INT3321 Positive_regulation of ALAS2 10 0.51 3.08 0.32 93.36
22 INT196375 Negative_regulation of Ppox 2 0.08 2.73 0 93.04
23 INT50291 Positive_regulation of HMBS 10 0.67 8.89 0.73 91.24
24 INT8047 Positive_regulation of Nts 20 0.67 7.96 10.35 91.08
25 INT8724 Positive_regulation of Mln 21 0.66 14.12 6.17 91.08
26 INT37865 Positive_regulation of Alad 5 0.27 3.13 0.6 90.64
27 INT40215 Negative_regulation of Fech 9 0.57 8.39 1.85 88.96
28 INT196373 Negative_regulation of Vmn2r81 1 0.02 1.96 0 87.08
29 INT127038 Gene_expression of Alas1 6 0.72 3.94 1.48 86.36
30 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 84.24
31 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 83.92
32 INT16656 Negative_regulation of Gene_expression of YY1 8 0.57 2.62 2.12 82.76
33 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 81.88
34 INT178338 Gene_expression of Tbx15 50 0.65 38.65 12.19 78.56
35 INT127039 Negative_regulation of Ppig 13 0.21 5.29 3.87 78.32
36 INT80223 Positive_regulation of Hmox1 128 0.68 77.71 17.64 76.72
37 INT127040 Negative_regulation of Alas1 2 0.35 0.72 0.54 75.12
38 INT3320 Regulation of ALAS2 3 0.33 0.93 1.05 71.84
39 INT118264 Binding of Hmbs 6 0.37 4.87 0.33 69.00
40 INT102746 Negative_regulation of Hmbs 11 0.59 8.35 0.77 68.64
41 INT102745 Positive_regulation of Hmbs 17 0.61 12.41 0.78 67.00
42 INT49246 Negative_regulation of Urod 1 0.22 1.04 0.11 59.60
43 INT196372 Positive_regulation of Alas1 1 0.19 1.91 0.22 57.48
44 INT39418 Negative_regulation of Tdo2 12 0.57 0.8 6.93 42.80
45 INT39419 Positive_regulation of Negative_regulation of Tdo2 3 0.43 0.19 1.09 42.80
46 INT196371 Gene_expression of Ireb2 1 0.41 1.95 0 38.72
47 INT196374 Negative_regulation of Positive_regulation of Alas1 1 0.16 0.67 0.12 35.80
48 INT70410 Positive_regulation of AKAP13 2 0.49 0.77 0.96 35.08
49 INT46038 Positive_regulation of ALAS1 3 0.60 0.9 1 25.00
50 INT46036 Regulation of ALAS1 2 0.39 0.23 0.72 25.00
51 INT196376 Positive_regulation of Gene_expression of Alas1 1 0.19 1.01 0.25 23.60
52 INT196377 Gene_expression of Nrf1 4 0.68 5.97 2.63 21.12
53 INT84130 Gene_expression of Foxo1 1 0.26 0.97 1.22 21.12
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