D:Hepatocellular Cancer

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Disease Term
Synonyms CARCINOMA HEPATOCELLULAR, Carcinomas Hepatocellular, Hepatocellular Cancers, Hepatocellular Carcinoma, Hepatocellular Carcinomas, Hepatocellular Dysplasia, Hepatocellular Hyperplasia, HEPATOCELLULAR NEOPLASIA, Hepatocellular Neoplasm, HEPATOCELLULAR NEOPLASMS, HEPATOCELLULAR SARCOMA
Documents 1610
Hot Single Events 200
Hot Interactions 121

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hepatocellular Cancer. They are ordered first by their relevance to Hepatocellular Cancer and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT87808 Binding of Gpt and HCC 3 0.04 5.09 0.07 100.00
2 INT179097 Binding of Myc and Vps54 1 0.01 2.42 0 100.00
3 INT348033 Fndc3b Positive_regulation of Vps54 1 0.00 1.87 0.03 100.00
4 INT278041 Binding of VEGFA and HCC 1 0.02 1.64 0 100.00
5 INT348012 Samsn1 Positive_regulation of Vps54 1 0.00 1.93 0.15 100.00
6 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 100.00
7 INT179096 Positive_regulation of Myc Positive_regulation of Positive_regulation of Vps54 1 0.02 1.14 0 100.00
8 INT355867 Binding of Afp and HCC 1 0.01 2.25 0.14 100.00
9 INT348021 Stat3 Regulation of Vps54 1 0.02 1.32 0.07 100.00
10 INT342625 Binding of IFN1@ and Vps54 1 0.03 1.18 0.3 100.00
11 INT355866 Binding of EXT1 and Afp 1 0.04 3.56 0 100.00
12 INT348017 Mapk8 Positive_regulation of Positive_regulation of Vps54 1 0.02 0.89 0.03 100.00
13 INT348044 Binding of Mapk8 and Mapk8ip3 Negative_regulation of Vps54 1 0.00 1.04 0.16 100.00
14 INT348043 Binding of Mapk8 and Mapk8ip3 Negative_regulation of Positive_regulation of Vps54 1 0.00 1.04 0.16 100.00
15 INT341316 Negative_regulation of Binding of RTN4R and HCC 1 0.02 0.79 0 100.00
16 INT326017 Binding of PCNA and HCC 1 0.00 0.99 0 100.00
17 INT341315 Binding of RTN4R and HCC 1 0.02 0.74 0 100.00
18 INT179093 Myc Positive_regulation of Vps54 1 0.02 2.31 0 100.00
19 INT346455 IFNA1 Regulation of HCC 1 0.02 1.64 0.23 100.00
20 INT130959 Binding of Gtf3a and Eif4h 1 0.05 0.29 0.08 100.00
21 INT130958 Binding of Eif4h and Ash1l 1 0.07 0.29 0.08 100.00
22 INT116124 Binding of AFP and HCC 2 0.20 1.72 0.15 100.00
23 INT320888 Binding of olt and HCC 1 0.00 1.62 0.06 100.00
24 INT348029 Re Positive_regulation of Vps54 1 0.01 0.44 0.07 100.00
25 INT348011 Binding of Samsn1 and Vps54 1 0.00 1.35 0.11 100.00
26 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0 100.00
27 INT179094 Gene_expression of Myc Positive_regulation of Vps54 1 0.02 0.54 0 100.00
28 INT285396 Binding of Adam17 and R3hcc1 1 0.15 0.93 0 100.00
29 INT253022 PTTG1 Negative_regulation of Negative_regulation of Trp53 1 0.03 1.34 0 99.84
30 INT323500 Ghrl Positive_regulation of Grb2 1 0.13 0.5 0 99.76
31 INT323495 Ghrl Positive_regulation of Irs1 1 0.20 0.5 0 99.76
32 INT323499 Ghrl Positive_regulation of Ins1 1 0.21 0.25 0 99.76
33 INT320267 CCNA2 Positive_regulation of CDK1 1 0.12 1.08 0.08 99.56
34 INT179871 IK Positive_regulation of SOCS3 1 0.01 1 0.1 99.44
35 INT315369 Binding of IL6 and Crp 1 0.10 2.09 0.3 99.36
36 INT323591 Negative_regulation of Binding of Aldh2 and Napa 1 0.02 0.17 0 99.16
37 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0 99.12
38 INT242479 Negative_regulation of Ciapin1 Negative_regulation of Bcl2 1 0.14 1.28 0 99.12
39 INT88500 RYBP Negative_regulation of Positive_regulation of Gtf3a 1 0.00 0.19 0.73 99.00
40 INT191890 Pbsn Negative_regulation of Binding of Prkca 1 0.03 0.29 0.18 98.96
41 INT191881 Pbsn Negative_regulation of Prkca 1 0.03 0.29 0.18 98.96
42 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1 98.90
43 INT314756 IL6 Positive_regulation of Gene_expression of Crp 2 0.13 4.58 0.48 98.88
44 INT313298 Negative_regulation of SQSTM1 Positive_regulation of KEAP1 1 0.39 0.39 0 98.86
45 INT313303 Negative_regulation of SQSTM1 Positive_regulation of GOPC 1 0.05 0.39 0 98.86
46 INT323590 Binding of Aldh2 and Napa 1 0.01 0.16 0 98.80
47 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37 98.76
48 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37 98.76
49 INT348034 Mapk8ip3 Negative_regulation of Mapk8 1 0.05 0.98 0.16 98.36
50 INT327338 Positive_regulation of Mapk1 Positive_regulation of Positive_regulation of VEGFA 1 0.05 0.93 0.05 98.24
51 INT306241 Ins1 Negative_regulation of Gene_expression of PCK1 1 0.00 0.91 0.08 98.00
52 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37 97.96
53 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37 97.96
54 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19 97.84
55 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32 97.76
56 INT348019 Negative_regulation of Binding of Mapk8 and Mapk8ip3 1 0.05 1.04 0.16 97.76
57 INT348030 Mapk8 Regulation of Re 1 0.17 0.95 0.06 97.60
58 INT280163 Twist1 Positive_regulation of Mod2 1 0.07 1.67 0 97.52
59 INT280164 Twist1 Negative_regulation of Mod2 1 0.06 1.76 0 97.24
60 INT201456 Hmox1 Positive_regulation of Gene_expression of Bcl2 1 0.06 0.74 0.08 96.80
61 INT52806 CYP2E1 Positive_regulation of RYBP 1 0.43 0.24 0.95 96.60
62 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12 96.56
63 INT308004 Rsph1 Positive_regulation of Mapk14 1 0.02 0.61 0.12 96.16
64 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0 95.48
65 INT179098 Myc Regulation of Binding of Max and Myc 1 0.17 0.52 0 95.48
66 INT179091 Binding of Max and Myc 1 0.16 0.52 0 95.48
67 INT355864 EXT1 Positive_regulation of Positive_regulation of Afp 1 0.05 0.93 0 95.44
68 INT335129 PPARA Positive_regulation of Gene_expression of Insig1 1 0.20 0.15 0.07 95.08
69 INT348025 Mapk8 Regulation of Gene_expression of Proc 1 0.00 0.58 0.08 94.84
70 INT298785 PPARA Positive_regulation of ACOX1 3 0.29 1.58 0.23 94.40
71 INT280833 Il1 Positive_regulation of Gene_expression of Crh 1 0.05 0.09 0.17 93.92
72 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11 93.92
73 INT252778 RAF1 Positive_regulation of Positive_regulation of ROS1 1 0.04 2.05 0.11 93.92
74 INT327314 Positive_regulation of Mapk1 Positive_regulation of Phosphorylation of Ttpa 1 0.02 0.91 0.05 93.68
75 INT327112 HCCS Positive_regulation of Gene_expression of SLCO1B3 1 0.03 0.65 0.19 92.64
76 INT355865 EXT1 Positive_regulation of Cm3 1 0.04 0.99 0 92.44
77 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0 92.40
78 INT348038 Binding of Fos and Hltf 1 0.01 0.45 0.03 92.28
79 INT348817 Binding of Fndc3b and Gopc 1 0.01 1.68 0 92.20
80 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37 91.60
81 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37 91.60
82 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37 90.64
83 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37 90.64
84 INT291641 Binding of DST and ESRRG 1 0.16 1.8 0.28 90.24
85 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 90.08
86 INT313310 KEAP1 Regulation of Gene_expression of SQSTM1 1 0.43 0.35 0 89.20
87 INT191879 Positive_regulation of Pbsn Negative_regulation of Positive_regulation of Mapk3 1 0.01 0.25 0.23 88.76
88 INT242481 Ad Regulation of Gene_expression of Ciapin1 1 0.00 0.63 0 88.52
89 INT242477 Ad Regulation of Ciapin1 1 0.00 0.63 0 88.52
90 INT348042 Positive_regulation of Mapk8 Regulation of Gene_expression of VEGFA 1 0.03 0.85 0.1 88.12
91 INT304281 IL8 Positive_regulation of TBK1 1 0.01 2.35 0.44 87.64
92 INT320887 Binding of TP63 and olt 1 0.01 2.15 0 87.40
93 INT312693 Binding of CCR6 and CCL20 2 0.34 2.33 0.53 86.80
94 INT115916 AHR Regulation of Gene_expression of SLC45A2 1 0.64 0.36 0.44 86.16
95 INT280008 Binding of IFNA1 and PAEP 2 0.08 1.29 0.25 85.96
96 INT115914 AHR Regulation of Gene_expression of PPIG 1 0.25 0.36 0.44 85.76
97 INT179868 HGF Positive_regulation of Binding of HGF and MET 1 0.05 0.35 0.04 85.44
98 INT115915 AHR Regulation of Gene_expression of CYP2B6 1 0.06 0.36 0.43 85.36
99 INT339695 Binding of CYP3A4 and TRO 1 0.06 0.57 0.05 84.96
100 INT191887 Pbsn Regulation of Phosphorylation of Mapk3 1 0.00 0.24 0.23 84.76
101 INT179872 Binding of HGF and MET 7 0.09 4.69 0.07 84.72
102 INT348032 Fndc3b Positive_regulation of Tlr2 1 0.01 1.3 0.2 84.64
103 INT343163 ACSL4 Regulation of Gene_expression of PTGS2 1 0.08 0.5 0 84.56
104 INT191885 Tlr4 Regulation of Phosphorylation of Mapk3 1 0.01 0.24 0.23 84.52
105 INT354925 ALB Positive_regulation of ALPP 1 0.34 1.69 0.09 84.40
106 INT348040 TNF Positive_regulation of Gene_expression of Tlr2 1 0.02 0.98 0.14 84.12
107 INT237907 Tlr4 Positive_regulation of Gene_expression of Tlr2 7 0.40 5.85 0.6 84.12
108 INT280841 Jun Positive_regulation of Gene_expression of Crh 1 0.35 0.16 0.1 84.00
109 INT323492 Ins1 Regulation of Gene_expression of Pck1 1 0.08 0.16 0 83.16
110 INT327337 MIR29A Negative_regulation of Ttpa 1 0.04 1.14 0.28 82.96
111 INT198019 NPY6R Negative_regulation of Gene_expression of SRC 1 0.06 1.75 0 82.88
112 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 82.80
113 INT144283 ACP1 Positive_regulation of ABCB1 1 0.63 0.6 0.81 82.40
114 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27 82.40
115 INT280836 Gene_expression of Fos Positive_regulation of Crh 1 0.09 0.17 0.1 81.84
116 INT242480 Ciapin1 Positive_regulation of Gene_expression of Jak2 1 0.27 1.05 0.07 81.72
117 INT242482 Ciapin1 Positive_regulation of Gene_expression of Bcl2l1 1 0.31 1.05 0.07 81.72
118 INT306238 Tead1 Regulation of Ins1 1 0.00 1.04 0.05 81.04
119 INT170495 Negative_regulation of Egf Positive_regulation of Mapk1 1 0.20 0.08 0 80.68
120 INT170496 Egf Positive_regulation of Mapk1 3 0.21 0.5 0.3 80.04
121 INT170497 Positive_regulation of Egf Positive_regulation of Mapk1 1 0.21 0.08 0 80.04
122 INT135130 Binding of CYP3A4 and NR1I2 1 0.34 0.31 0 80.00
123 INT348014 Binding of Tbk1 and Gramd3 1 0.00 1.33 0.2 79.84
124 INT242475 Ciapin1 Positive_regulation of Gene_expression of Anxa2 1 0.01 1.13 0.06 79.76
125 INT338785 Gene_expression of TMPRSS6 Positive_regulation of Positive_regulation of HAMP 1 0.10 0.24 0 79.60
126 INT339707 TRO Positive_regulation of CYP3A4 1 0.12 0.97 0.04 79.52
127 INT219406 AHR Positive_regulation of CBL 1 0.03 0.65 0 79.40
128 INT102553 HGF Positive_regulation of Phosphorylation of MAPK1 1 0.40 0.49 0.48 78.80
129 INT280006 Binding of CLTC and IFNA1 1 0.04 1.59 0 78.40
130 INT198007 MTOR Regulation of Gene_expression of GOPC 1 0.08 1.33 0 77.76
131 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 77.64
132 INT348013 Negative_regulation of Binding of Irf3 and Tbk1 1 0.21 1.41 0.2 77.64
133 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04 77.56
134 INT348031 Binding of Irf3 and Tbk1 1 0.17 2.82 0.4 77.24
135 INT338789 HFE2 Regulation of HAMP 1 0.11 1 0.09 77.20
136 INT338771 HFE2 Regulation of HFE2 Regulation of HAMP 1 0.01 0.23 0 77.20
137 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14 77.12
138 INT348041 Binding of IFNA1 and Irf3 1 0.02 1.41 0.2 77.04
139 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05 76.88
140 INT340565 Gopc Regulation of Phosphorylation of Mapk8 1 0.04 0.92 0 76.88
141 INT283361 AXIN2 Negative_regulation of GSK 1 0.09 1.67 0 76.64
142 INT283362 AXIN2 Negative_regulation of APC 1 0.10 1.67 0 76.64
143 INT340563 Gopc Regulation of Phosphorylation of Mapk14 1 0.04 0.91 0 76.56
144 INT316498 Il6 Positive_regulation of IL6 1 0.49 0.89 0 75.84
145 INT197998 KDR Negative_regulation of KDR Negative_regulation of VEGFA 1 0.04 0.95 0 75.72
146 INT198024 CDCP1 Negative_regulation of MTOR 1 0.00 0.97 0 75.72
147 INT198010 KDR Negative_regulation of MTOR 1 0.11 0.95 0 75.72
148 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28 75.52
149 INT135129 NR1I2 Regulation of Transcription of CYP3A4 1 0.58 0.6 0 75.28
150 INT316493 Il6 Positive_regulation of Il11ra1 1 0.64 1.69 0.4 75.28
151 INT102552 HGF Positive_regulation of MAPK3 1 0.38 0.47 0.47 75.08
152 INT102555 HGF Positive_regulation of MAPK1 1 0.38 0.47 0.47 75.08
153 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28 75.04
154 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28 75.04
155 INT135128 Binding of NR1I2 and NR1H4 1 0.09 0.57 0 75.00
156 INT135127 Binding of RXRB and NR1I2 1 0.29 0.57 0 75.00
157 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94 75.00
158 INT141242 Binding of SYP and DNLZ 1 0.29 1.74 0.41 75.00
159 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89 75.00
160 INT102556 HGF Positive_regulation of Phosphorylation of ELK1 1 0.10 0.46 0.47 75.00
161 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6 75.00
162 INT119276 Negative_regulation of CYBB Negative_regulation of Positive_regulation of ROS1 1 0.09 1.18 0.97 75.00
163 INT119275 Negative_regulation of CYBB Negative_regulation of Gene_expression of ROS1 1 0.09 1.18 0.97 75.00
164 INT119274 CYBB Positive_regulation of ROS1 1 0.11 1.11 0.88 75.00
165 INT149096 PITX2 Positive_regulation of Gene_expression of Egr1 1 0.01 1.23 0.19 75.00
166 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15 75.00
167 INT149092 PITX2 Positive_regulation of RFFL 1 0.00 1.51 0.15 75.00
168 INT160159 Gene_expression of CYP2C9 Positive_regulation of HSP90B2P 1 0.13 0.53 0.09 75.00
169 INT198016 Localization of KDR Negative_regulation of VEGFA 1 0.08 0.95 0 74.84
170 INT348027 Gramd3 Negative_regulation of Irf3 1 0.00 1.39 0.2 74.36
171 INT198013 MTOR Regulation of Gene_expression of MCL1 1 0.29 1.3 0 74.24
172 INT198000 Gene_expression of KDR Negative_regulation of VEGFA 1 0.08 0.94 0 73.48
173 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21 73.36
174 INT346459 Binding of RNASE1 and ROS1 1 0.06 1.42 0.18 73.12
175 INT198012 KDR Negative_regulation of VEGFA 1 0.08 0.93 0 73.08
176 INT307207 Ppara Positive_regulation of Apoa2 1 0.10 0.94 0.25 72.64
177 INT198002 KDR Negative_regulation of PDGFA 1 0.09 0.94 0 72.28
178 INT144281 ACP1 Negative_regulation of Positive_regulation of MAPK1 1 0.27 0.58 0.94 72.20
179 INT144282 ACP1 Negative_regulation of Positive_regulation of PHOSPHO2 1 0.05 0.58 0.94 72.20
180 INT144284 ACP1 Negative_regulation of PHOSPHO2 1 0.05 0.58 0.93 71.80
181 INT144285 ACP1 Negative_regulation of MAPK1 1 0.37 0.58 0.93 71.32
182 INT317387 Amp1 Positive_regulation of Prkag1 1 0.04 0.34 0.07 71.04
183 INT266423 Binding of HMGB1 and Mapk3 1 0.04 0.9 0.2 70.48
184 INT266410 Binding of HMGB1 and Mapk14 1 0.03 0.91 0.2 70.48
185 INT266416 Binding of HMGB1 and Mapk1 1 0.06 0.9 0.2 70.48
186 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2 70.48
187 INT344254 Binding of PARP1 and CASP3 1 0.06 0.94 0.06 70.40
188 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09 64.92
189 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6 64.76
190 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58 64.76
191 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 64.48
192 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2 63.40
193 INT287893 VEGFA Positive_regulation of Localization of WISP1 1 0.03 1.23 0.1 63.40
194 INT340554 Myod1 Positive_regulation of Negative_regulation of Mapk1 1 0.28 0.25 0 63.12
195 INT340551 Myod1 Positive_regulation of Mapk1 1 0.19 0.25 0 63.12
196 INT340559 Myod1 Positive_regulation of Myog 1 0.12 0.25 0 63.12
197 INT340560 Myog Positive_regulation of Mapk1 1 0.07 0.25 0 62.76
198 INT340557 Myog Positive_regulation of Negative_regulation of Mapk1 1 0.16 0.25 0 62.76
199 INT313308 Binding of SQSTM1 and KEAP1 1 0.46 1.16 0.1 62.48
200 INT313293 Binding of KEAP1 and GOPC 1 0.04 0.24 0 62.48

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hepatocellular Cancer. They are ordered first by their pain relevance and then by number of times they were reported in Hepatocellular Cancer. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 100.00
2 INT72782 Positive_regulation of HCC 41 0.40 63.74 2.46 100.00
3 INT79140 Binding of HCC 36 0.31 46.96 1.87 100.00
4 INT21487 Negative_regulation of HCC 18 0.49 29.81 1.88 100.00
5 INT169431 Gene_expression of Vps54 17 0.21 21.76 0.96 100.00
6 INT242467 Positive_regulation of Gene_expression of Ciapin1 1 0.70 27.67 0.26 100.00
7 INT70242 Localization of HCC 18 0.66 23.95 2.35 100.00
8 INT169432 Positive_regulation of Vps54 10 0.16 13.96 0.53 100.00
9 INT139852 Regulation of HCC 14 0.39 14.54 0.97 100.00
10 INT222845 Gene_expression of Chuk 27 0.52 25.15 2.67 100.00
11 INT106263 Gene_expression of R3hcc1 4 0.44 9.36 0.88 100.00
12 INT106262 Positive_regulation of R3hcc1 4 0.24 8.81 0.38 100.00
13 INT38153 Binding of Vps54 6 0.31 7.31 0.57 100.00
14 INT38154 Negative_regulation of Vps54 7 0.37 7.99 1.99 100.00
15 INT198032 Negative_regulation of Gene_expression of HCC 4 0.21 8.16 0.08 100.00
16 INT234454 Regulation of Gene_expression of HCC 6 0.18 8.3 0.06 100.00
17 INT167101 Positive_regulation of Gene_expression of HCC 4 0.20 7.49 0.07 100.00
18 INT326179 Negative_regulation of R3hcc1 1 0.15 4.07 0 100.00
19 INT285395 Binding of R3hcc1 4 0.16 3.34 0.19 100.00
20 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 100.00
21 INT277347 Localization of Vps54 3 0.09 3.14 0.63 100.00
22 INT277348 Negative_regulation of Gene_expression of Vps54 1 0.05 2.38 0.05 100.00
23 INT347989 Positive_regulation of Gene_expression of Vps54 1 0.02 1.82 0.09 100.00
24 INT179883 Transcription of HCC 2 0.31 1.7 0.03 100.00
25 INT270992 Positive_regulation of Positive_regulation of HCC 2 0.13 2.22 0.12 100.00
26 INT222850 Positive_regulation of Gene_expression of Chuk 7 0.34 4.91 0.44 100.00
27 INT242466 Regulation of Vps54 1 0.01 1.06 0.04 100.00
28 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15 100.00
29 INT106264 Negative_regulation of Gene_expression of Vcam1 13 0.53 10.47 3.55 100.00
30 INT342611 Positive_regulation of Transcription of Vps54 1 0.04 1.09 0.66 100.00
31 INT342610 Transcription of Vps54 1 0.05 1.08 0.65 100.00
32 INT49105 Gene_expression of Vcam1 157 0.78 157.27 43.01 100.00
33 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 100.00
34 INT3882 Positive_regulation of SARNP 2 0.31 1.46 0.82 100.00
35 INT283364 Positive_regulation of Negative_regulation of HCC 1 0.13 1.78 0.05 100.00
36 INT211265 Positive_regulation of Gene_expression of Hk2 1 0.04 2.26 0.14 100.00
37 INT278057 Negative_regulation of Binding of HCC 1 0.07 0.67 0 100.00
38 INT342615 Negative_regulation of MHAa97h7 1 0.01 0.55 0.06 100.00
39 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 100.00
40 INT53983 Gene_expression of Opcml 30 0.78 10.35 9.69 100.00
41 INT176264 Binding of PCNA 21 0.21 9.08 0.51 100.00
42 INT321843 Regulation of Binding of HCC 1 0.16 0.7 0 100.00
43 INT165105 Localization of Mapk8 7 0.69 4.45 0.76 100.00
44 INT935 Localization of Gtf3a 124 0.70 35.72 43.3 100.00
45 INT130957 Localization of Ash1l 1 0.41 0.29 0.08 100.00
46 INT144158 Negative_regulation of Positive_regulation of AFP 1 0.42 1.66 0.06 100.00
47 INT164381 Regulation of Positive_regulation of MAPK3 2 0.60 1.49 1.03 100.00
48 INT240849 Negative_regulation of Phosphorylation of Irs1 11 0.43 4.74 0.85 100.00
49 INT240855 Negative_regulation of Phosphorylation of Irs2 4 0.34 2.18 0.07 100.00
50 INT7581 Binding of ADHD1 132 0.46 135.1 19.73 100.00
51 INT225703 Positive_regulation of Transcription of Entpd2 1 0.21 0.62 0.15 100.00
52 INT279374 Gene_expression of MOK 1 0.09 0.26 0 100.00
53 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.98
54 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 99.98
55 INT7994 Gene_expression of Lta 113 0.67 69.81 19.59 99.98
56 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 99.96
57 INT142953 Positive_regulation of Gene_expression of TRPV2 2 0.70 5.56 0.64 99.96
58 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 99.96
59 INT179080 Positive_regulation of Positive_regulation of Myc 1 0.70 5.2 0.03 99.96
60 INT7776 Gene_expression of Abcb1b 63 0.75 21.35 14.92 99.96
61 INT57057 Gene_expression of APC 131 0.78 122.24 8.7 99.92
62 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 99.92
63 INT172452 Gene_expression of Myc 121 0.78 69.56 1.36 99.92
64 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 99.92
65 INT172445 Positive_regulation of Gene_expression of Myc 58 0.70 39.62 0.25 99.92
66 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.92
67 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.92
68 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 99.92
69 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 99.92
70 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78 99.92
71 INT134795 Positive_regulation of Scrib 30 0.22 36.91 2.81 99.92
72 INT198027 Localization of MCL1 5 0.72 7.46 0.51 99.92
73 INT98647 Positive_regulation of Mdk 65 0.59 32.93 15.67 99.90
74 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18 99.90
75 INT59198 Regulation of Ccnd1 11 0.47 6.54 0.9 99.90
76 INT14823 Gene_expression of MET 103 0.75 51.92 32.48 99.88
77 INT277343 Negative_regulation of Trerf1 1 0.16 0.69 0.29 99.88
78 INT176533 Positive_regulation of Gene_expression of MET 13 0.67 7.17 0.06 99.88
79 INT57560 Positive_regulation of GLA 14 0.54 5.01 0.83 99.88
80 INT242471 Gene_expression of Ciapin1 1 0.78 54.25 0.44 99.84
81 INT303585 Gene_expression of Coro1c 1 0.63 18.63 0.15 99.84
82 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 99.84
83 INT242459 Negative_regulation of Ciapin1 1 0.59 10.17 0.03 99.84
84 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 99.84
85 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69 99.84
86 INT242460 Negative_regulation of Gene_expression of Ciapin1 1 0.59 4.97 0.05 99.84
87 INT242455 Regulation of Gene_expression of Ciapin1 1 0.62 3.75 0.04 99.84
88 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1 99.84
89 INT650 Gene_expression of Afp 13 0.78 7.44 1.47 99.84
90 INT71786 Phosphorylation of MAPK1 256 0.82 110.09 46.17 99.84
91 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11 99.84
92 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68 99.84
93 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15 99.84
94 INT184054 Negative_regulation of Gene_expression of Socs1 7 0.53 9.18 2.22 99.84
95 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 99.84
96 INT175214 Gene_expression of HSPB2 21 0.72 22.84 0.81 99.84
97 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 99.84
98 INT195679 Positive_regulation of Positive_regulation of APC 6 0.50 4.43 0.05 99.84
99 INT25152 Gene_expression of SAA1 37 0.75 53.56 8.07 99.84
100 INT46311 Regulation of Gene_expression of SAA1 4 0.27 1.51 0.51 99.84
101 INT242474 Regulation of Negative_regulation of Ciapin1 1 0.24 0.87 0 99.84
102 INT242458 Positive_regulation of Negative_regulation of Ciapin1 1 0.44 0.87 0 99.84
103 INT91462 Positive_regulation of Phosphorylation of MAPK1 99 0.67 40.28 18.99 99.84
104 INT279383 Negative_regulation of Ttpa 2 0.06 16.02 3.37 99.84
105 INT140620 Gene_expression of HYOU1 5 0.66 3.72 0.54 99.84
106 INT151586 Positive_regulation of Prkag1 51 0.54 18.7 3.34 99.84
107 INT6894 Gene_expression of CNR1 168 0.78 74.07 62.84 99.84
108 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 99.84
109 INT81664 Positive_regulation of Gene_expression of Pnoc 12 0.68 2.51 9.75 99.84
110 INT41099 Localization of Mdk 5 0.64 2.38 2.89 99.84
111 INT64743 Positive_regulation of olt 19 0.40 16.46 3.86 99.80
112 INT62854 Positive_regulation of Chp 1 0.21 2.74 0.49 99.80
113 INT7678 Localization of Alb 142 0.81 80.93 22.49 99.80
114 INT120062 Binding of AIP 4 0.42 28.86 3.91 99.80
115 INT200100 Negative_regulation of Gene_expression of G6PC 1 0.05 0.54 0.06 99.80
116 INT24080 Negative_regulation of Mtor 64 0.37 41.56 5.19 99.78
117 INT53871 Gene_expression of Socs1 32 0.71 22.83 6.21 99.78
118 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76 99.78
119 INT239095 Negative_regulation of PTTG1 2 0.32 8.24 0.09 99.78
120 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8 99.78
121 INT93165 Gene_expression of TRPV2 32 0.78 12.49 5.62 99.76
122 INT61117 Gene_expression of Ppara 158 0.68 69.3 15.98 99.76
123 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 99.76
124 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88 99.76
125 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 99.76
126 INT86187 Positive_regulation of AKT1 199 0.69 122.13 19.44 99.76
127 INT8075 Localization of Crh 64 0.81 25.41 19.45 99.76
128 INT144729 Negative_regulation of Gcsh 2 0.40 1.26 0.21 99.76
129 INT350827 Localization of SELS 1 0.62 1.24 0.19 99.76
130 INT108172 Positive_regulation of Gene_expression of Abcb1b 5 0.67 1.64 1.76 99.74
131 INT108173 Gene_expression of Abcb1b 14 0.75 8.61 4.26 99.74
132 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 99.72
133 INT2579 Protein_catabolism of Ins1 43 0.99 9.91 5.14 99.72
134 INT22213 Localization of Gpt 52 0.78 34.05 12.94 99.72
135 INT2580 Negative_regulation of Protein_catabolism of Ins1 8 0.58 1.34 0.81 99.72
136 INT285394 Binding of Adam17 1 0.31 0.93 0 99.72
137 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 99.70
138 INT6628 Transcription of Eef1a1 4 0.16 2.59 1.8 99.68
139 INT240819 Phosphorylation of Irs2 10 0.71 4.75 0.25 99.68
140 INT48239 Binding of Gtf3a 52 0.33 23.14 6.45 99.68
141 INT52809 Gene_expression of OR1E1 1 0.02 0.29 0.66 99.68
142 INT83708 Negative_regulation of MAPK1 156 0.57 84.93 27.85 99.66
143 INT154303 Negative_regulation of DCPS 27 0.36 33.83 5.45 99.66
144 INT277349 Gene_expression of Trerf1 1 0.30 4.61 0.05 99.64
145 INT303584 Positive_regulation of Gene_expression of Coro1c 1 0.38 4.19 0 99.64
146 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37 99.64
147 INT47207 Negative_regulation of Ahr 25 0.52 16.11 3.02 99.64
148 INT227043 Negative_regulation of Dre 2 0.19 1.13 0.49 99.64
149 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 99.62
150 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2 99.60
151 INT151168 Gene_expression of Pten 60 0.78 35.63 10.54 99.60
152 INT666 Gene_expression of Jun 124 0.78 54.61 33.67 99.60
153 INT154139 Gene_expression of Top2a 2 0.72 4.23 0.19 99.60
154 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 99.60
155 INT179889 Negative_regulation of CDKN1B 4 0.57 1.71 0.21 99.60
156 INT135009 Positive_regulation of BPI 8 0.54 3.8 1.59 99.60
157 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.60
158 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 99.60
159 INT71281 Positive_regulation of Gene_expression of CYP2C9 13 0.62 5.11 1.3 99.60
160 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 99.60
161 INT187186 Gene_expression of HAB1 1 0.01 0.93 0.67 99.60
162 INT5379 Gene_expression of Fos 656 0.78 255.5 292.54 99.60
163 INT44478 Negative_regulation of PTEN 32 0.57 27.45 0.63 99.60
164 INT28110 Transcription of MET 9 0.67 9.43 1.15 99.60
165 INT20066 Gene_expression of Mdk 38 0.76 21.41 13.4 99.60
166 INT345315 Gene_expression of MMP16 1 0.22 4.37 0.28 99.60
167 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 99.60
168 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 99.60
169 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68 99.60
170 INT225708 Transcription of Entpd2 1 0.24 0.61 0.15 99.60
171 INT120525 Gene_expression of SLCO1B3 2 0.57 1.47 0.33 99.56
172 INT56925 Negative_regulation of TSC1 54 0.52 63.39 1.87 99.56
173 INT341319 Localization of RTN4R 1 0.25 0.88 0.08 99.56
174 INT42319 Gene_expression of Hpd 5 0.44 11.25 0.9 99.56
175 INT348792 Gene_expression of Fndc3b 1 0.04 9.86 0.13 99.56
176 INT191804 Transcription of CD24 10 0.72 12.43 1.25 99.56
177 INT227048 Positive_regulation of Regulation of Dre 1 0.21 0.4 0 99.56
178 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 99.52
179 INT355901 Gene_expression of Zeb1 1 0.41 0.66 0 99.52
180 INT27096 Positive_regulation of Nfkb1 325 0.70 195.11 109.06 99.52
181 INT13824 Transcription of Egf 6 0.56 0.94 0.33 99.52
182 INT138955 Transcription of EGFR 18 0.71 11.39 0.78 99.52
183 INT87212 Negative_regulation of Positive_regulation of Nfkb1 74 0.57 38.21 28.31 99.52
184 INT104979 Gene_expression of MITF 51 0.62 54.83 6.91 99.52
185 INT102174 Gene_expression of FASN 11 0.65 6.4 0.67 99.52
186 INT281657 Positive_regulation of CLEC4F 2 0.10 2.02 0.49 99.52
187 INT164777 Negative_regulation of Gclm 1 0.21 0.51 0.06 99.52
188 INT283021 Binding of Prot 1 0.01 1.11 0 99.52
189 INT73982 Gene_expression of Hmox1 141 0.78 119.43 32.17 99.48
190 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.48
191 INT80228 Positive_regulation of Gene_expression of Hmox1 68 0.70 62.88 14.01 99.48
192 INT115386 Gene_expression of Ppara 779 0.77 549.99 128.36 99.48
193 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 99.48
194 INT28215 Gene_expression of CDKN1A 196 0.76 113.9 18.3 99.48
195 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22 99.48
196 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 99.48
197 INT122039 Positive_regulation of Gene_expression of Ppara 144 0.68 113.55 28.55 99.48
198 INT115277 Gene_expression of HSD3B1 1 0.18 0.36 0.21 99.46
199 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24 99.44
200 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 99.44
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