D:Hepatopulmonary Syndrome

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pChart

Disease Term
Synonyms Abnormal Arterial Oxygenation, Hepato Pulmonary Syndrome, Hepato Pulmonary Syndromes, Hepatopulmonary Syndromes, Liver Dysfunction, Pulmonary Vascular Dilatation, Syndrome Hepato Pulmonary, Syndrome Hepatopulmonary, Syndromes Hepato Pulmonary, SYNDROMES HEPATOPULMONARY
Documents 18
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hepatopulmonary Syndrome. They are ordered first by their relevance to Hepatopulmonary Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT332685 Trib3 Positive_regulation of Binding of Ros1 1 0.01 0.74 0.12 27.44
2 INT285979 Ros1 Positive_regulation of Trib3 2 0.02 2.18 0.2 24.32
3 INT332687 Ros1 Positive_regulation of Crk 1 0.17 0.77 0.12 23.76
4 INT332689 Binding of Edn1 and Ros1 1 0.08 0.71 0.14 7.44
5 INT350363 Gatm Negative_regulation of NOS1 1 0.00 0.31 0.17 5.00
6 INT332688 Ros1 Positive_regulation of Binding of Edn1 1 0.10 0.57 0.09 5.00
7 INT332684 Binding of Edn1 and Lep 1 0.09 1.11 0.04 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hepatopulmonary Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Hepatopulmonary Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT87780 Gene_expression of Gja1 22 0.77 5.84 4.24 99.56
2 INT65211 Binding of Prkcg 38 0.48 14.75 16.92 98.96
3 INT84170 Positive_regulation of Gene_expression of Ccl2 58 0.69 48.79 32.43 97.00
4 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 96.60
5 INT12765 Positive_regulation of Phosphorylation of Prkcg 59 0.66 20.16 34.67 94.76
6 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78 94.32
7 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 94.32
8 INT12763 Phosphorylation of Prkcg 167 0.82 38.91 89.63 90.84
9 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 85.40
10 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 84.52
11 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68 84.52
12 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15 84.52
13 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76 84.52
14 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 83.84
15 INT83198 Positive_regulation of Nos3 78 0.64 35.69 17.71 83.48
16 INT222609 Binding of Tlr4 8 0.43 4.03 1.98 66.64
17 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 58.32
18 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 58.32
19 INT7153 Positive_regulation of Regulation of Edn1 2 0.35 1.97 0.57 58.32
20 INT4636 Positive_regulation of Regulation of Agt 4 0.50 1.3 0.3 58.32
21 INT1158 Regulation of Agt 106 0.61 29.4 30.29 57.40
22 INT5806 Regulation of Edn1 63 0.62 23.46 13.88 57.40
23 INT289546 Negative_regulation of Gene_expression of Sirt1 5 0.42 3.1 0.31 51.28
24 INT332681 Regulation of Positive_regulation of Sirt1 1 0.16 0.69 0.11 45.76
25 INT289543 Regulation of Gene_expression of Sirt1 3 0.45 1.81 0.11 45.76
26 INT289550 Positive_regulation of Sirt1 25 0.69 13.59 0.8 44.64
27 INT289547 Positive_regulation of Positive_regulation of Sirt1 2 0.69 0.76 0.11 44.64
28 INT289575 Gene_expression of Sirt1 47 0.77 29.29 1.47 41.44
29 INT289553 Positive_regulation of Gene_expression of Sirt1 21 0.69 20.43 1.03 41.44
30 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 33.04
31 INT115528 Binding of Ros1 37 0.41 22.96 5.5 27.44
32 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 22.32
33 INT10173 Binding of Tnf 45 0.48 35.6 14.32 22.16
34 INT181581 Regulation of Positive_regulation of Edn1 4 0.23 3.76 0.51 9.68
35 INT68758 Positive_regulation of Ros1 125 0.46 82.72 25.27 9.28
36 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4 6.40
37 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.68
38 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 5.00
39 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 5.00
40 INT9131 Positive_regulation of Prkcg 431 0.70 130.8 302.41 5.00
41 INT1352 Localization of Acot1 728 0.80 73.01 296.01 5.00
42 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
43 INT9132 Negative_regulation of Prkcg 279 0.59 88.05 203.47 5.00
44 INT69764 Positive_regulation of Cnr1 126 0.70 67.8 91.49 5.00
45 INT74376 Gene_expression of Cnr1 173 0.78 73.43 89.7 5.00
46 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 5.00
47 INT1472 Positive_regulation of Ins1 349 0.69 146.2 86.36 5.00
48 INT39777 Regulation of Prkcg 90 0.62 31.52 68.17 5.00
49 INT55344 Gene_expression of Ros1 396 0.54 217.64 59.98 5.00
50 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
51 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
52 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 5.00
53 INT49017 Negative_regulation of Gene_expression of Nos2 169 0.59 80.64 52.67 5.00
54 INT76620 Gene_expression of Cnr2 93 0.78 34.7 50.14 5.00
55 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 5.00
56 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04 5.00
57 INT4735 Gene_expression of Acot1 80 0.71 13.22 26.68 5.00
58 INT74377 Regulation of Cnr1 38 0.59 16.93 24.77 5.00
59 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 5.00
60 INT72060 Positive_regulation of Gene_expression of Ros1 127 0.41 76.76 20.91 5.00
61 INT5048 Binding of Edn1 55 0.47 18.86 19.16 5.00
62 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38 5.00
63 INT9525 Regulation of Positive_regulation of Prkcg 20 0.62 7.82 16.18 5.00
64 INT55343 Localization of Ros1 39 0.60 34.51 12.5 5.00
65 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 5.00
66 INT113317 Regulation of Cnr2 17 0.52 10.27 10.68 5.00
67 INT95271 Negative_regulation of Nos3 46 0.53 24.1 9.71 5.00
68 INT55014 Positive_regulation of Ednrb 31 0.70 16.61 9.68 5.00
69 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71 5.00
70 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 5.00
71 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19 5.00
72 INT45101 Positive_regulation of Gene_expression of Acot1 13 0.40 2.2 6.55 5.00
73 INT21953 Binding of Ednra 12 0.33 4.72 4.56 5.00
74 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08 5.00
75 INT102515 Binding of Nos3 19 0.45 9.41 4.01 5.00
76 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5 5.00
77 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88 5.00
78 INT131498 Gene_expression of Cybb 15 0.40 8.73 2.34 5.00
79 INT55853 Positive_regulation of Positive_regulation of Edn1 11 0.61 6.5 2.21 5.00
80 INT21813 Gene_expression of Apoa2 10 0.61 3.68 1.81 5.00
81 INT72021 Localization of Ednra 7 0.58 3.13 1.53 5.00
82 INT12429 Negative_regulation of Spdya 5 0.20 1.07 1.49 5.00
83 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39 5.00
84 INT54044 Negative_regulation of EDA 7 0.42 2.54 1.14 5.00
85 INT132667 Regulation of Transcription of NOS1 1 0.30 2.58 0.95 5.00
86 INT197032 Regulation of Ncf1 3 0.45 2.84 0.79 5.00
87 INT141864 Negative_regulation of Binding of Nos3 3 0.39 2.27 0.56 5.00
88 INT10983 Binding of Apoa2 7 0.45 4.21 0.52 5.00
89 INT115202 Positive_regulation of Positive_regulation of Ednra 2 0.39 2.88 0.49 5.00
90 INT27534 Negative_regulation of Gba 10 0.57 6.23 0.38 5.00
91 INT158794 Binding of EDA 2 0.47 1.61 0.33 5.00
92 INT47453 Positive_regulation of Positive_regulation of Apoa2 3 0.31 1.17 0.32 5.00
93 INT67227 Positive_regulation of Binding of Apoa2 2 0.26 1.31 0.25 5.00
94 INT332683 Positive_regulation of Gene_expression of Ddah1 1 0.12 1.75 0.05 5.00
95 INT332682 Gene_expression of Ddah1 1 0.13 1.75 0.05 5.00
96 INT170179 Binding of Vwf 4 0.36 0.93 0 5.00
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