D:Hereditary Corneal Dystrophies

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pChart

Disease Term
Synonyms CORNEAL DYSTROPHY HEREDITARY, Corneal Granular Dystrophies, CORNEAL GRANULAR DYSTROPHY, Corneal Macular Dystrophies, Corneal Macular Dystrophy, Corneal Stromal Dystrophies, Corneal Stromal Dystrophy, Dystrophies Corneal Granular, DYSTROPHIES CORNEAL MACULAR, DYSTROPHIES CORNEAL STROMAL, Dystrophies Groenouw S
Documents 4
Hot Single Events 5
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hereditary Corneal Dystrophies. They are ordered first by their relevance to Hereditary Corneal Dystrophies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT238460 Binding of TGFBI and MLLT4-AS1 1 0.01 0.2 0.06 5.00
2 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hereditary Corneal Dystrophies. They are ordered first by their pain relevance and then by number of times they were reported in Hereditary Corneal Dystrophies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT273159 Gene_expression of CHED1 1 0.36 1.83 0 99.96
2 INT55655 Gene_expression of DCN 17 0.75 7.98 5.98 99.48
3 INT273153 Positive_regulation of CHED1 1 0.27 1.53 0 95.48
4 INT201028 Localization of TGFBI 3 0.71 0.34 0 94.20
5 INT2116 Negative_regulation of VSX1 29 0.36 10.67 1.89 93.96
6 INT165342 Gene_expression of TGFBI 13 0.59 5.81 0.39 70.00
7 INT11508 Positive_regulation of TGFBI 24 0.70 19.81 15.78 37.56
8 INT38055 Positive_regulation of KRT3 4 0.64 1.05 0.39 37.56
9 INT242853 Binding of TGFBI 10 0.42 1.38 0.07 23.72
10 INT53189 Gene_expression of VSX1 32 0.69 10.59 7.21 5.00
11 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
12 INT52678 Positive_regulation of VSX1 15 0.42 3.94 3.64 5.00
13 INT2117 Regulation of VSX1 15 0.30 3.38 3.38 5.00
14 INT4596 Positive_regulation of SCD 18 0.42 22.59 3.26 5.00
15 INT44873 Negative_regulation of LCAT 16 0.59 6.92 3.13 5.00
16 INT85084 Gene_expression of KRT19 66 0.73 42.56 1.82 5.00
17 INT121335 Localization of SCD 10 0.68 6.81 1.51 5.00
18 INT126370 Localization of VSX1 6 0.56 1.7 1.28 5.00
19 INT59175 Localization of TNMD 4 0.70 4.14 0.71 5.00
20 INT4597 Regulation of SCD 5 0.39 2.25 0.5 5.00
21 INT189634 Regulation of DCN 3 0.25 1.69 0.49 5.00
22 INT273158 Binding of COL8A2 1 0.33 2.02 0.22 5.00
23 INT218762 Localization of ZEB1 2 0.65 0.09 0.2 5.00
24 INT238461 Positive_regulation of MTDH 1 0.05 0.28 0.08 5.00
25 INT273145 Negative_regulation of COL8A2 1 0.40 0.83 0.06 5.00
26 INT273155 Gene_expression of COL8A2 1 0.53 0.74 0.05 5.00
27 INT232943 Binding of KRT12 3 0.47 0.88 0 5.00
28 INT232980 Binding of KRT3 2 0.29 0.43 0 5.00
29 INT273142 Gene_expression of Smc3 1 0.09 0.35 0 5.00
30 INT273143 Negative_regulation of Tat 1 0.01 2.3 0 5.00
31 INT273144 Binding of CHED1 1 0.19 1.7 0 5.00
32 INT273146 Positive_regulation of Binding of TNMD 1 0.02 0.21 0 5.00
33 INT273147 Binding of TBCD 1 0.05 0 0 5.00
34 INT273148 Localization of LCAT 1 0.38 0.91 0 5.00
35 INT273149 Localization of GCDH 1 0.06 0.77 0 5.00
36 INT273150 Regulation of CHED1 1 0.24 0.09 0 5.00
37 INT273151 Binding of GCDH 1 0.04 0.25 0 5.00
38 INT273152 Positive_regulation of Localization of LCAT 1 0.26 0.91 0 5.00
39 INT273154 Positive_regulation of Localization of SCD 1 0.03 0.94 0 5.00
40 INT273156 Gene_expression of SLC4A11 1 0.41 0.84 0 5.00
41 INT273157 Localization of COL8A2 1 0.26 0.09 0 5.00
42 INT273160 Binding of TNMD 4 0.42 1.72 0 5.00
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