D:Herpes Simplex Virus Infection

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Disease Term
Synonyms COLD SORE, COLD SORES, Dendritic Ulcer, Dendritic Ulcers, Genital Herpes, Gingivostomatitis, Herpes Labialis, Herpes Simplex Virus Infections, Herpetic, Herpetic Keratitis, Herpetic Stomatitis
Documents 917
Hot Single Events 123
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Herpes Simplex Virus Infection. They are ordered first by their relevance to Herpes Simplex Virus Infection and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT210029 PROC Negative_regulation of PRTN3 1 0.00 1.06 0.18 94.64
2 INT154716 Binding of MON1B and CD209 1 0.01 1.76 0.08 89.48
3 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 57.24
4 INT317546 Oprm1 Regulation of Prkca 1 0.06 0.4 0.82 56.24
5 INT317513 Oprm1 Regulation of Positive_regulation of Src 1 0.09 0.4 0.82 56.24
6 INT317570 Oprm1 Regulation of Src 1 0.04 0.4 0.82 56.24
7 INT317573 Binding of Oprm1 and Pik3r1 1 0.12 0.33 0.71 52.04
8 INT340816 Tnfrsf14 Regulation of Gene_expression of Btla 1 0.11 1.09 0.18 50.00
9 INT340822 Trav6-3 Regulation of Gene_expression of Btla 1 0.07 0.97 0.15 50.00
10 INT340819 Regulation of Binding of Ly6g6d and Tnfrsf14 1 0.01 1.58 0.12 50.00
11 INT340818 Binding of Ly6g6d and Tnfrsf14 1 0.01 1.57 0.12 50.00
12 INT74033 Binding of IGHG3 and Ighg1 2 0.08 0.87 0.06 50.00
13 INT340823 Btla Regulation of Ly6g6d 1 0.04 0.99 0.03 50.00
14 INT348334 Gml Positive_regulation of Micrl 1 0.01 0.51 0 50.00
15 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 48.36
16 INT317523 Oprm1 Positive_regulation of Gene_expression of Akt1 1 0.32 0.05 0.53 44.60
17 INT317574 Oprm1 Positive_regulation of Akt1 1 0.22 0.05 0.52 44.60
18 INT317565 Oprm1 Positive_regulation of Pik3r1 1 0.14 0.05 0.52 44.60
19 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 28.40
20 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
21 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
22 INT317517 Binding of Nos1 and Oprm1 1 0.17 0.22 3.85 5.00
23 INT317511 Ppp1r9b Regulation of Oprm1 3 0.27 0.33 3.85 5.00
24 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
25 INT317522 Akt1 Positive_regulation of Phosphorylation of Nos1 1 0.43 0.4 3.13 5.00
26 INT317563 Binding of Hint1 and Oprm1 1 0.20 0.25 3.03 5.00
27 INT317551 Binding of Akt1 and Oprm1 1 0.19 0.21 2.74 5.00
28 INT317528 Ppp1r9b Regulation of Grin1 1 0.18 0.2 2.48 5.00
29 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38 5.00
30 INT211748 Binding of Pag1 and Mors1 2 0.07 0.2 2.26 5.00
31 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
32 INT317524 Binding of Camk2a and Grin1 1 0.17 0.06 2.21 5.00
33 INT317540 Camk2a Negative_regulation of Oprm1 1 0.19 0 1.98 5.00
34 INT317558 Binding of Oprm1 and Rgs17 1 0.18 0 1.59 5.00
35 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55 5.00
36 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55 5.00
37 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 5.00
38 INT317538 Binding of Neu3 and Mors1 1 0.00 0 1.51 5.00
39 INT317509 Oprm1 Negative_regulation of Phosphorylation of Oprd1 1 0.00 0 1.46 5.00
40 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
41 INT317519 Grin1 Positive_regulation of Negative_regulation of Oprm1 1 0.14 0 1.31 5.00
42 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 5.00
43 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29 5.00
44 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
45 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25 5.00
46 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
47 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
48 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
49 INT317553 Binding of Car2 and Grin1 1 0.07 0 1.14 5.00
50 INT317549 Negative_regulation of Camk2a Negative_regulation of Phosphorylation of Oprm1 1 0.19 0 1.14 5.00
51 INT317548 Positive_regulation of Akt1 Positive_regulation of Prkca 1 0.15 0 1.11 5.00
52 INT317516 Binding of Oprm1 and Negative_regulation of Positive_regulation of Akt1 1 0.17 0.1 1.11 5.00
53 INT317527 Binding of Hint1 and Nos1 1 0.27 0.1 1.11 5.00
54 INT317512 Binding of Oprm1 and Prkca 1 0.07 0.13 1.1 5.00
55 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 5.00
56 INT317561 Binding of Grin1 and Oprm1 1 0.14 0.09 1.08 5.00
57 INT317531 Regulation of Binding of Grin1 and Mors1 1 0.08 0.06 1.05 5.00
58 INT317534 Regulation of Binding of Camk2a and Grin1 1 0.20 0.06 1.05 5.00
59 INT317552 Binding of Calm3 and Car2 2 0.06 0.07 1.05 5.00
60 INT317535 Binding of Grin1 and Mors1 1 0.07 0.06 1.04 5.00
61 INT317554 Akt1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 5.00
62 INT317532 Grin1 Regulation of Negative_regulation of Oprm1 1 0.18 0.07 1 5.00
63 INT317518 Src Regulation of Negative_regulation of Oprm1 1 0.16 0.07 1 5.00
64 INT317555 Nos1 Regulation of Negative_regulation of Oprm1 1 0.21 0.07 1 5.00
65 INT317544 Camk2a Regulation of Negative_regulation of Oprm1 1 0.20 0.07 1 5.00
66 INT317564 Pik3r1 Regulation of Negative_regulation of Oprm1 1 0.13 0.07 1 5.00
67 INT317568 Prkca Regulation of Negative_regulation of Oprm1 1 0.10 0.07 1 5.00
68 INT317550 Binding of Hint1 and Rgs20 1 0.32 0.07 0.98 5.00
69 INT317529 Binding of Hint1 and Rgs17 1 0.32 0.07 0.98 5.00
70 INT317543 Pag1 Positive_regulation of Oprm1 1 0.12 0.73 0.97 5.00
71 INT317567 Binding of Akt1 and Nos1 1 0.22 0 0.96 5.00
72 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
73 INT317559 Binding of Hint1 and Pla2g4a 1 0.01 0.06 0.94 5.00
74 INT317541 Oprd1 Negative_regulation of Akt1 1 0.06 0 0.91 5.00
75 INT317530 Negative_regulation of Binding of Nos1 and Oprm1 1 0.21 0.06 0.9 5.00
76 INT339318 Ngf Positive_regulation of Pik3cg 1 0.02 0.69 0.87 5.00
77 INT317515 Binding of Hint1 and Prkca 1 0.13 0.17 0.87 5.00
78 INT317556 Phosphorylation of Gopc Positive_regulation of Akt1 1 0.10 0.08 0.82 5.00
79 INT317514 Akt1 Regulation of Localization of Oprm1 1 0.21 0.07 0.82 5.00
80 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
81 INT308176 TNF Regulation of Tnfrsf1a 1 0.05 1.19 0.75 5.00
82 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75 5.00
83 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
84 INT317547 Src Positive_regulation of Positive_regulation of Grin1 1 0.17 0 0.72 5.00
85 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71 5.00
86 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 5.00
87 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 5.00
88 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
89 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65 5.00
90 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 5.00
91 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 5.00
92 INT308175 Negative_regulation of Mapk14 Negative_regulation of Localization of TNF 1 0.03 0.89 0.61 5.00
93 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 5.00
94 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56 5.00
95 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54 5.00
96 INT317537 Oprm1 Positive_regulation of Phosphorylation of Nos1 1 0.16 0 0.5 5.00
97 INT308170 Binding of thd and Tnfrsf14 1 0.00 1.84 0.46 5.00
98 INT308171 Binding of TNF and thd 1 0.00 1.84 0.45 5.00
99 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
100 INT317521 Camk2a Negative_regulation of Binding of Calm3 1 0.11 0 0.43 5.00
101 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 5.00
102 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 5.00
103 INT330377 Positive_regulation of Binding of TLR2 and TLR9 1 0.09 2.79 0.32 5.00
104 INT330381 Binding of TLR2 and TLR9 1 0.07 2.77 0.32 5.00
105 INT330389 Positive_regulation of Binding of TLR2 and TLR8 1 0.08 2.78 0.32 5.00
106 INT317566 Car2 Positive_regulation of Camk2a 2 0.19 0.58 0.32 5.00
107 INT317545 Calm3 Positive_regulation of Camk2a 1 0.17 0 0.31 5.00
108 INT317557 Calm3 Positive_regulation of Car2 1 0.05 0 0.31 5.00
109 INT330383 Binding of TLR2 and TLR3 1 0.07 2.77 0.31 5.00
110 INT330378 Positive_regulation of Binding of TLR2 and TLR3 1 0.10 2.78 0.31 5.00
111 INT330387 Binding of TLR2 and TLR8 1 0.06 2.77 0.31 5.00
112 INT186345 Binding of Gast and Stat6 1 0.03 2.19 0.3 5.00
113 INT317571 Grin1 Regulation of Trpv1 1 0.00 0 0.29 5.00
114 INT317562 Binding of Grin1 and Gnptab 1 0.00 0 0.29 5.00
115 INT317533 Akt1 Positive_regulation of Nos1 1 0.43 0 0.28 5.00
116 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 5.00
117 INT317510 Binding of Grin2a and Gnptab 1 0.00 0 0.26 5.00
118 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24 5.00
119 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23 5.00
120 INT186374 Il13 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
121 INT186371 Il4 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
122 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22 5.00
123 INT186391 TNF Positive_regulation of Gene_expression of Il17a 1 0.03 0.38 0.22 5.00
124 INT186358 Il1 Positive_regulation of Gene_expression of Il17a 1 0.02 0.38 0.22 5.00
125 INT330382 IFNA1 Positive_regulation of Gene_expression of IL10 1 0.06 0.83 0.21 5.00
126 INT186353 Binding of Il12a and Il1 1 0.21 0.38 0.2 5.00
127 INT330371 Binding of TLR3 and Ifx 1 0.17 1.12 0.2 5.00
128 INT329068 Tlr9 Positive_regulation of Localization of IFNA1 1 0.03 1.54 0.19 5.00
129 INT330388 Binding of PTPRC and TLR2 1 0.00 1.19 0.16 5.00
130 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
131 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
132 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15 5.00
133 INT186357 Binding of Irf1 and Stat6 1 0.04 2.09 0.14 5.00
134 INT186372 Binding of Irf1 and Stat1 1 0.04 2.06 0.14 5.00
135 INT330370 Positive_regulation of Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
136 INT330369 Binding of IL10 and Il4 1 0.01 0.47 0.13 5.00
137 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
138 INT186379 Il12a Positive_regulation of Binding of IFNA1 1 0.03 0.07 0.12 5.00
139 INT330380 CD40 Regulation of Gene_expression of IFNA1 1 0.17 0.78 0.1 5.00
140 INT208983 Binding of Ca2 and Kcnma1 2 0.01 0.28 0.1 5.00
141 INT208979 Binding of Itpr3 and Trpc3 1 0.00 0.33 0.09 5.00
142 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08 5.00
143 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08 5.00
144 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08 5.00
145 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08 5.00
146 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08 5.00
147 INT186369 Negative_regulation of Binding of Gast and Stat1 1 0.04 1.04 0.07 5.00
148 INT208989 Binding of CALM1 and Fig4 1 0.01 0 0.07 5.00
149 INT186347 Binding of Irf2 and Rfc1 1 0.00 1.02 0.07 5.00
150 INT186361 Binding of Gast and Irf1 1 0.01 1.03 0.07 5.00
151 INT186364 Binding of Irf2 and Nos2 1 0.04 1.02 0.07 5.00
152 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
153 INT186341 Binding of Irf1 and Irf2 1 0.02 1.04 0.07 5.00
154 INT186366 Binding of Stat1 and Stat6 1 0.12 1.04 0.07 5.00
155 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
156 INT186375 TNF Negative_regulation of Gene_expression of Il12b 1 0.03 0.78 0.06 5.00
157 INT270199 Icos Positive_regulation of Localization of Il10 1 0.03 0.63 0.06 5.00
158 INT186390 Binding of TNF and Irf1 1 0.02 0.99 0.05 5.00
159 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05 5.00
160 INT208988 Binding of CALM1 and Itpr3 1 0.01 0.15 0.05 5.00
161 INT186263 Binding of TNF and GORASP1 1 0.10 0.99 0.05 5.00
162 INT186383 Binding of Nos2 and GORASP1 1 0.12 0.93 0.05 5.00
163 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05 5.00
164 INT186377 Binding of Irf1 and GORASP1 1 0.12 0.87 0.05 5.00
165 INT186350 Gtf3a Negative_regulation of Transcription of Nos2 1 0.00 0.77 0.04 5.00
166 INT208982 Negative_regulation of Binding of Itpr3 and Trpc3 1 0.00 0.17 0.04 5.00
167 INT186352 Il13 Negative_regulation of Transcription of Nos2 1 0.05 0.76 0.04 5.00
168 INT186359 Stat6 Negative_regulation of Il4 1 0.06 0.78 0.04 5.00
169 INT186362 Il4 Negative_regulation of Transcription of Nos2 1 0.04 0.77 0.04 5.00
170 INT186356 Gtf3a Regulation of Positive_regulation of Nos2 1 0.00 0.91 0.04 5.00
171 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04 5.00
172 INT330372 Ifx Positive_regulation of IFNA1 1 0.54 0.67 0.04 5.00
173 INT186360 Stat6 Negative_regulation of Transcription of Nos2 1 0.08 0.78 0.04 5.00
174 INT186348 Irf1 Regulation of Positive_regulation of Nos2 1 0.02 0.91 0.04 5.00
175 INT186387 IFNA1 Positive_regulation of Transcription of Nos2 1 0.03 0.7 0.04 5.00
176 INT270206 Hdl1 Positive_regulation of Gene_expression of IL2 1 0.01 0.35 0.03 5.00
177 INT304757 Binding of HIVEP1 and ERVV-2 1 0.00 1.41 0.03 5.00
178 INT186382 TNF Regulation of Il12a 1 0.06 0.72 0.03 5.00
179 INT186363 Binding of Stat6 and Positive_regulation of Positive_regulation of Irf2 1 0.05 0.4 0.03 5.00
180 INT186384 Il4 Negative_regulation of Gene_expression of IFNA1 1 0.01 0.48 0.03 5.00
181 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03 5.00
182 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03 5.00
183 INT186342 Il13 Negative_regulation of Positive_regulation of Nos2 1 0.03 0.65 0.03 5.00
184 INT186386 Il12a Regulation of Gene_expression of TNF 1 0.06 0.66 0.03 5.00
185 INT304756 Regulation of Binding of HIVEP1 and ERVV-2 1 0.00 1.46 0.03 5.00
186 INT293368 Binding of CSH1 and Ppia 1 0.00 0.19 0.03 5.00
187 INT186354 Stat6 Positive_regulation of Positive_regulation of Irf2 1 0.06 0.4 0.03 5.00
188 INT186344 Binding of Tnfrsf1a and Tnfrsf1b 1 0.20 0.48 0 5.00
189 INT186378 IFNA1 Positive_regulation of Il12a 1 0.03 0.76 0 5.00
190 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0 5.00
191 INT186346 Binding of Irf8 and Irf1 1 0.05 1.25 0 5.00
192 INT256502 Sis Regulation of Tg(CAG-EGFP)D4Nagy 1 0.00 0.1 0 5.00
193 INT186392 Binding of TNF and P4hb 1 0.02 0.47 0 5.00
194 INT353985 Binding of GYPA and POMT1 1 0.04 0.72 0 5.00
195 INT293357 RORC Regulation of PPP2R4 1 0.00 0 0 5.00
196 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0 5.00
197 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0 5.00
198 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0 5.00
199 INT202599 Binding of IL2 and PTPN5 1 0.03 0.12 0 5.00
200 INT270204 TNF Positive_regulation of Il4 1 0.01 0.53 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Herpes Simplex Virus Infection. They are ordered first by their pain relevance and then by number of times they were reported in Herpes Simplex Virus Infection. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT29885 Gene_expression of GGH 13 0.67 12.77 0.96 100.00
2 INT162058 Binding of GGH 8 0.37 3.45 0.2 100.00
3 INT29879 Positive_regulation of GGH 9 0.70 3.13 2.62 100.00
4 INT170474 Regulation of Binding of GGH 1 0.45 0.53 0 100.00
5 INT68640 Regulation of Pnoc 18 0.54 7.6 17.27 99.84
6 INT49171 Gene_expression of Nos1 241 0.78 140.7 104.76 99.68
7 INT166486 Negative_regulation of Gene_expression of Slc6a9 1 0.42 1.27 1.29 99.68
8 INT166487 Negative_regulation of Gene_expression of Slc6a5 1 0.48 1.27 1.29 99.68
9 INT151520 Negative_regulation of Slc6a9 5 0.58 1.86 1.86 99.68
10 INT166484 Negative_regulation of Slc6a5 1 0.35 1.26 1.28 99.68
11 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 99.42
12 INT49172 Regulation of Nos1 43 0.52 27.53 23.66 99.40
13 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 99.32
14 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.24
15 INT9556 Negative_regulation of NAV1 47 0.59 28.49 49.33 99.08
16 INT89854 Regulation of Nos2 49 0.61 42.58 24.1 99.04
17 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.04
18 INT43707 Positive_regulation of CCBE1 11 0.07 8.22 4.86 99.04
19 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 99.00
20 INT127427 Negative_regulation of Ptgdr 1 0.17 1.66 1.12 98.76
21 INT67214 Transcription of Oprl1 9 0.69 1.8 5.66 98.72
22 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 98.72
23 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.66
24 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7 98.66
25 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 98.64
26 INT26705 Transcription of ADRA1D 6 0.67 3.99 2.74 98.64
27 INT79484 Regulation of Negative_regulation of Pnoc 2 0.37 0.92 1.62 98.52
28 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 98.46
29 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 98.40
30 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 98.40
31 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 98.40
32 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 98.26
33 INT73351 Negative_regulation of Pnoc 13 0.42 5.71 14.17 98.16
34 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 98.04
35 INT88081 Negative_regulation of Gene_expression of Oprm1 45 0.59 16.56 37.5 98.04
36 INT14054 Positive_regulation of H2-Ab1 10 0.69 2.98 6.25 97.88
37 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 97.88
38 INT166485 Gene_expression of Slc6a5 2 0.64 1.51 1.36 97.84
39 INT127428 Negative_regulation of Ptger1 8 0.42 5.26 4.15 97.56
40 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 97.28
41 INT49170 Negative_regulation of Nos1 116 0.59 60.66 58.87 97.26
42 INT166488 Gene_expression of Slc6a9 2 0.77 1.45 6.46 97.24
43 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 97.00
44 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 97.00
45 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 96.48
46 INT50130 Positive_regulation of Ptger3 13 0.67 5.23 6.47 96.32
47 INT143494 Binding of DCPS 24 0.29 24.41 3.67 96.24
48 INT45109 Binding of C5AR1 10 0.37 5.77 2.69 96.16
49 INT154730 Regulation of Slc6a5 3 0.43 1.91 1.56 96.08
50 INT104774 Regulation of PGE 5 0.39 2.5 1.76 96.04
51 INT195203 Binding of Tenc1 14 0.32 13.97 8.28 95.72
52 INT17692 Negative_regulation of C5AR1 5 0.57 2.99 1.04 95.36
53 INT53222 Regulation of Negative_regulation of C5AR1 1 0.26 0.61 0.13 95.36
54 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 95.36
55 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.92
56 INT1665 Positive_regulation of Pag1 270 0.68 186.63 229.87 94.52
57 INT28861 Binding of Gh 61 0.46 25.61 6.38 94.32
58 INT186290 Binding of Pvrl1 8 0.11 4.82 0.46 93.80
59 INT340809 Gene_expression of Btla 1 0.77 27.14 1.69 93.72
60 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 93.64
61 INT74232 Binding of RPSAP8 1 0.06 0.93 0.07 93.44
62 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 93.28
63 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 93.00
64 INT16782 Binding of ERLEC1 15 0.10 8.23 1.7 93.00
65 INT44118 Binding of CD209 10 0.35 8.83 0.69 93.00
66 INT68559 Negative_regulation of Gli3 5 0.37 4.56 4.93 92.84
67 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 91.96
68 INT170662 Localization of NPCDR1 1 0.37 1.14 0 91.64
69 INT22502 Gene_expression of Hal 21 0.53 9.8 3.32 91.36
70 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 90.92
71 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 90.48
72 INT91238 Regulation of Negative_regulation of Oprm1 6 0.45 1.4 7.85 90.20
73 INT114025 Transcription of Nos1 20 0.70 16.48 15.63 90.08
74 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 90.08
75 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 90.08
76 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 90.08
77 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 89.64
78 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94 89.64
79 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29 89.64
80 INT5331 Positive_regulation of Gene_expression of NPEPPS 6 0.49 3.74 1.81 89.64
81 INT17275 Gene_expression of HIVEP1 267 0.75 232.07 24.06 89.52
82 INT53948 Regulation of Gene_expression of Cpox 40 0.51 20.97 13.87 89.52
83 INT17276 Negative_regulation of Gene_expression of HIVEP1 27 0.42 26.85 2.61 89.52
84 INT99116 Binding of Cacna2d3 15 0.48 7.33 13.58 89.48
85 INT133375 Binding of Pdha1 1 0.07 3.09 7.07 89.48
86 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 89.12
87 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 89.08
88 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 88.88
89 INT200435 Binding of polymerase 6 0.16 5.56 0.47 88.32
90 INT317143 Regulation of D9Mgi9 1 0.01 1.66 0 88.28
91 INT140200 Regulation of Cacna2d3 4 0.45 1.48 2.53 87.84
92 INT154717 Regulation of Binding of DCPS 1 0.35 1.76 0.08 87.24
93 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 87.08
94 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 87.04
95 INT105021 Binding of GOPC 187 0.40 60.39 20.38 86.24
96 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 84.40
97 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83 84.40
98 INT123419 Binding of NAV1 37 0.48 7.09 26.43 84.40
99 INT51946 Gene_expression of Apold1 13 0.39 3.56 6.08 84.32
100 INT84703 Negative_regulation of Nqo1 8 0.38 7.1 4.05 84.04
101 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 83.52
102 INT8634 Gene_expression of Nfasc 23 0.68 9.16 14.96 83.28
103 INT11696 Gene_expression of HLA-A 50 0.78 41.25 14.1 83.24
104 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 83.24
105 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 83.20
106 INT186878 Binding of RTEL1 7 0.12 4.75 0 82.96
107 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 82.84
108 INT210030 Negative_regulation of Binding of NPEPPS 1 0.05 0.49 0.13 82.84
109 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 82.80
110 INT93908 Negative_regulation of Dpyd 9 0.45 3.19 0.78 82.72
111 INT64110 Positive_regulation of Gene_expression of Nos1 68 0.70 58.11 51.64 82.68
112 INT76469 Positive_regulation of Gene_expression of Prkca 18 0.46 7.9 13.36 82.68
113 INT92516 Positive_regulation of Gene_expression of Grin1 8 0.45 2.53 3.77 82.68
114 INT99020 Gene_expression of Nlrp3 23 0.75 18.86 4.4 82.36
115 INT92348 Binding of NPEPPS 3 0.04 2.94 0.71 82.32
116 INT111100 Gene_expression of Dusp1 18 0.76 14.81 5.21 82.04
117 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 81.80
118 INT64159 Gene_expression of Prkca 90 0.78 34.65 55.97 81.36
119 INT71868 Regulation of Tenc1 9 0.52 10.73 4.09 81.32
120 INT87698 Gene_expression of WAS 25 0.58 8.75 11.83 80.72
121 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 80.24
122 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 80.16
123 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55 80.16
124 INT317508 Binding of Hint1 1 0.40 1.37 6.31 79.92
125 INT89046 Positive_regulation of P2RX2 15 0.67 7.25 7.52 79.88
126 INT6926 Regulation of Pag1 72 0.39 55.79 65.09 79.84
127 INT7800 Localization of Pag1 51 0.56 33.06 53.74 79.84
128 INT60728 Gene_expression of Serpinb1-ps1 10 0.59 6.92 0.93 79.60
129 INT230419 Gene_expression of NUDCD1 2 0.06 1.16 0.16 79.60
130 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 79.36
131 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 78.64
132 INT130793 Positive_regulation of Gene_expression of Nfasc 1 0.02 1.76 0.99 78.64
133 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 78.60
134 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 78.48
135 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 78.24
136 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 78.16
137 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 78.00
138 INT199510 Negative_regulation of STIP1 15 0.47 20.99 1.12 77.88
139 INT45818 Gene_expression of C4A 35 0.75 26.4 3.52 77.76
140 INT32580 Gene_expression of C4B 24 0.75 17.95 7.75 77.40
141 INT189177 Positive_regulation of Gene_expression of FSCN1 12 0.11 3.77 6.12 76.64
142 INT85943 Negative_regulation of Nos2 161 0.59 108.56 42.65 76.36
143 INT140201 Positive_regulation of Binding of Cacna2d3 1 0.69 0.62 1.07 76.12
144 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 76.04
145 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 75.00
146 INT340793 Transcription of Ly6g6d 1 0.06 4.21 0.16 75.00
147 INT95342 Gene_expression of GRIN2B 21 0.75 4.99 9.32 75.00
148 INT3323 Gene_expression of ALAS2 10 0.58 7.51 0.21 75.00
149 INT340797 Positive_regulation of Gene_expression of Btla 1 0.69 12.73 0.95 75.00
150 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 75.00
151 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 75.00
152 INT225988 Regulation of Del(7)Tyr<c-1DThWb>-p 6 0.03 8.79 0.58 75.00
153 INT225986 Negative_regulation of Regulation of Del(7)Tyr<c-1DThWb>-p 3 0.03 3.14 0.1 75.00
154 INT107575 Positive_regulation of Gene_expression of Atf3 25 0.69 27.37 14.55 74.48
155 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 74.32
156 INT133423 Positive_regulation of Micrl 2 0.18 2.51 0.28 74.32
157 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64 74.08
158 INT48248 Gene_expression of Scn10a 38 0.78 19.3 25.05 74.08
159 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 74.08
160 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 73.88
161 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47 73.52
162 INT183467 Negative_regulation of TBK1 6 0.12 9.89 5.41 73.36
163 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 72.88
164 INT101578 Regulation of Cnr2 26 0.62 16.7 19.12 72.60
165 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 72.60
166 INT103666 Regulation of Mors1 20 0.28 3.6 18.86 72.56
167 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 72.32
168 INT304760 Positive_regulation of ERVV-2 1 0.01 2.62 0 71.12
169 INT274271 Negative_regulation of Negative_regulation of NARFL 1 0.06 5.13 0.22 71.04
170 INT274273 Regulation of Gene_expression of NARFL 3 0.10 4.39 0.2 71.04
171 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 70.52
172 INT133371 Negative_regulation of Binding of Dll1 1 0.41 0.5 1.22 69.72
173 INT55148 Binding of Dll1 5 0.48 0.66 2.97 69.04
174 INT3682 Binding of Ppr1 10 0.42 1.87 2.96 68.40
175 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 68.32
176 INT9381 Positive_regulation of TRPV1 523 0.70 187.4 276.05 68.16
177 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 67.80
178 INT35368 Positive_regulation of Tk1 9 0.53 4.68 1.81 67.08
179 INT81102 Positive_regulation of Positive_regulation of Tk1 2 0.35 1.45 0.61 67.08
180 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 66.00
181 INT72141 Binding of Apoe 11 0.37 10.91 3.27 65.84
182 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8 65.84
183 INT5454 Localization of CRH 124 0.79 79.18 41.53 65.44
184 INT81103 Phosphorylation of Tk1 4 0.40 3.07 0.87 65.12
185 INT72884 Positive_regulation of Tenc1 13 0.42 14.01 7.67 65.12
186 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 65.12
187 INT43507 Gene_expression of Gabbr1 79 0.78 28.53 38.22 65.04
188 INT12444 Binding of Gabrd 26 0.48 4.7 11.23 64.88
189 INT149314 Negative_regulation of CAV2 5 0.42 1.21 2.76 64.88
190 INT73755 Localization of Scn10a 2 0.81 1.82 1.76 64.72
191 INT25392 Positive_regulation of Gene_expression of Csf2 41 0.49 34.28 8.36 64.48
192 INT719 Negative_regulation of SGCG 96 0.57 47.91 30.22 63.60
193 INT168399 Localization of Cnr2 12 0.81 4.37 6.77 63.52
194 INT151939 Gene_expression of NPCDR1 4 0.65 1.65 0 63.48
195 INT11766 Negative_regulation of H2-Ab1 15 0.43 5.27 12.32 63.36
196 INT25383 Gene_expression of Csf2 222 0.76 152.93 43.32 63.04
197 INT79358 Gene_expression of ERVW-1 65 0.75 29.9 1.31 62.20
198 INT139078 Gene_expression of Tnip1 2 0.51 1.93 0.64 62.20
199 INT304762 Regulation of ERVV-2 1 0.00 2.09 0.07 62.08
200 INT193816 Gene_expression of SYCP3 4 0.65 3.55 1.09 61.96
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