D:Herpes Zoster

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Disease Term
Synonyms Acute Posterior Ganglionitis, Chickenpox, Human Herpesvirus 3, Post Herpetic Neuralgia, RAMSAY HUNT SYNDROME, Shingles, Type 3 Human Herpesvirus, TYPE III HUMAN HERPESVIRUS, Varicella, Varicella Zoster, Varicella Zoster Virus Infection
Documents 2017
Hot Single Events 200
Hot Interactions 10

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Herpes Zoster. They are ordered first by their relevance to Herpes Zoster and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT64242 Binding of Gast and TSS 1 0.08 1.73 0.09 100.00
2 INT107268 Binding of ITGAL and NCR3 1 0.01 2.76 2.07 96.92
3 INT107269 Binding of HLA-A and NCR3 1 0.35 1.42 1.1 96.92
4 INT107264 Binding of TNF and NCR3 1 0.30 1.42 1.1 96.92
5 INT107263 Binding of HLA-DRB1 and NCR3 1 0.40 1.42 1.1 96.92
6 INT107265 Binding of HLA-DRB1 and ITGAL 1 0.01 1.41 1.1 96.52
7 INT107266 Binding of HLA-DRB1 and TNF 1 0.29 1.41 1.1 96.16
8 INT107267 Binding of HLA-A and TNF 1 0.34 1.41 1.1 96.16
9 INT325807 CXCL13 Positive_regulation of CISH 1 0.16 3.65 0.89 90.16
10 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 89.68
11 INT281733 LTK Regulation of IgG 1 0.00 1.37 0.03 77.00
12 INT295005 Binding of TNFRSF11A and Tnfsf11 3 0.20 2.02 0.09 75.20
13 INT295006 Binding of TNFRSF11A and Tnfrsf11b 2 0.10 1.6 0.04 75.20
14 INT295003 Binding of Tnfrsf11b and Tnfsf11 3 0.22 1.85 0.08 75.00
15 INT315814 Tst Positive_regulation of Localization of RTEL1 1 0.02 2.19 0 61.72
16 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05 54.56
17 INT321890 Slc3a2 Regulation of Dkk1 1 0.01 0.93 0.04 50.28
18 INT352392 Binding of ENOSF1 and Recql4 1 0.02 6.62 0 50.00
19 INT252347 Cd70 Positive_regulation of Cd27 1 0.20 1.06 0.25 44.12
20 INT252349 Binding of Cd70 and Mthfd1 Positive_regulation of Cd27 1 0.03 1.07 0.25 44.12
21 INT191497 Binding of REN and NLRP3 1 0.02 0.55 0.27 43.32
22 INT252340 Binding of Cd70 and Mthfd1 1 0.03 1.05 0.24 43.00
23 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 39.28
24 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 36.04
25 INT191499 CMA1 Positive_regulation of NLRP3 1 0.02 0.42 0.3 32.36
26 INT191502 Binding of CMA1 and NLRP3 1 0.01 0.42 0.3 32.36
27 INT191504 CPN2 Positive_regulation of NLRP3 1 0.00 0.37 0.27 32.00
28 INT250803 Binding of SARS and MBL3P 1 0.09 1.7 0.04 31.44
29 INT191498 Binding of CTSG and NLRP3 1 0.07 0.37 0.25 31.28
30 INT191496 CTSG Positive_regulation of NLRP3 1 0.09 0.37 0.25 31.28
31 INT191536 Klk1c2 Positive_regulation of NLRP3 1 0.02 0.36 0.24 30.64
32 INT191537 Binding of Klk1c2 and NLRP3 1 0.02 0.36 0.24 30.64
33 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25 28.88
34 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 28.72
35 INT191492 Binding of AGT and NLRP3 1 0.01 0.35 0.23 28.36
36 INT36999 Binding of HLA-DRB2 and TNFRSF25 1 0.05 3.46 0.91 25.00
37 INT191505 NLRP3 Positive_regulation of Protein_catabolism of EDN1 1 0.00 1.1 0.28 24.24
38 INT191500 ACE Positive_regulation of Localization of KNG1 1 0.10 0.17 0.24 21.32
39 INT191495 NLRP3 Positive_regulation of Protein_catabolism of ECE1 1 0.01 1.09 0.28 21.20
40 INT191501 NLRP3 Positive_regulation of ECE1 1 0.01 1.09 0.28 20.08
41 INT305038 CD99 Regulation of DES 1 0.12 1.25 0 20.04
42 INT252343 Gene_expression of Cd70 Positive_regulation of Positive_regulation of Cd27 1 0.20 0.45 0.03 14.20
43 INT106676 Binding of Trpv1 and Phax 18 0.34 4.19 12.36 5.00
44 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
45 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 5.00
46 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
47 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
48 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
49 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
50 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
51 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
52 INT140659 Phax Positive_regulation of Trpv1 3 0.49 0.68 2.18 5.00
53 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
54 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
55 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
56 INT261831 Mapk1 Negative_regulation of Hspg2 1 0.00 1.26 1.42 5.00
57 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
58 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3 5.00
59 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29 5.00
60 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
61 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
62 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
63 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
64 INT231391 Binding of Lpar1 and Rbm39 1 0.00 1.04 1.04 5.00
65 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
66 INT167173 Binding of Ccl2 and Ccr2 2 0.30 1.15 0.98 5.00
67 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93 5.00
68 INT265566 Binding of PDE4D and PTPN5 1 0.03 0.81 0.85 5.00
69 INT140660 Phax Negative_regulation of Trpv1 2 0.08 0.58 0.84 5.00
70 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
71 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
72 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
73 INT281651 Phax Positive_regulation of Gene_expression of Trpv1 1 0.09 0.89 0.79 5.00
74 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
75 INT261834 Itpr3 Positive_regulation of Prkca 2 0.01 0.33 0.78 5.00
76 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
77 INT231390 Pla2g4a Regulation of Pla2g2a 1 0.08 0.92 0.77 5.00
78 INT231388 Pla2g4a Regulation of Pla2g6 1 0.08 0.92 0.77 5.00
79 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
80 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
81 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
82 INT221415 IRF6 Positive_regulation of Gene_expression of IL10 2 0.05 1.73 0.75 5.00
83 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
84 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
85 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
86 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
87 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
88 INT261845 NGF Positive_regulation of Trpa1 1 0.04 0.73 0.71 5.00
89 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
90 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
91 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
92 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
93 INT261835 Camk2a Positive_regulation of Prkca 1 0.01 0.32 0.66 5.00
94 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
95 INT320152 IL6 Positive_regulation of IL1RN 2 0.23 2.59 0.66 5.00
96 INT191494 IL6 Positive_regulation of Binding of CRP 1 0.02 1.65 0.65 5.00
97 INT261832 Trpv1 Negative_regulation of Trpa1 1 0.10 0.58 0.64 5.00
98 INT261830 Hspg2 Negative_regulation of Trpa1 1 0.01 0.58 0.63 5.00
99 INT281650 Trpv1 Positive_regulation of Localization of Calca 1 0.12 0.71 0.61 5.00
100 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
101 INT261828 Igf1 Regulation of Localization of Trpv2 1 0.02 1.04 0.58 5.00
102 INT281648 Negative_regulation of Binding of Trpv1 and Fig4 1 0.14 0.69 0.55 5.00
103 INT281647 Binding of Trpv1 and Fig4 1 0.12 0.68 0.55 5.00
104 INT281649 Negative_regulation of Binding of Calca and Trpv1 1 0.13 0.67 0.54 5.00
105 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
106 INT327999 Binding of FPR2 and FPR3 1 0.02 3.72 0.53 5.00
107 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
108 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 5.00
109 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 5.00
110 INT172096 Binding of HLA-E and Il27ra 2 0.01 1.32 0.48 5.00
111 INT261839 Binding of Car2 and Trpv1 1 0.03 0 0.45 5.00
112 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
113 INT186373 Il6 Positive_regulation of Gene_expression of Il17a 2 0.14 1.52 0.42 5.00
114 INT186385 Binding of TNF and Tnfrsf1b 4 0.30 3.24 0.42 5.00
115 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 5.00
116 INT221417 IL12A Positive_regulation of Binding of IFN1@ 1 0.14 0.98 0.33 5.00
117 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 5.00
118 INT313915 Binding of Il12a and Il23a 2 0.16 0.44 0.31 5.00
119 INT186345 Binding of Gast and Stat6 1 0.03 2.19 0.3 5.00
120 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 5.00
121 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 5.00
122 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 5.00
123 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 5.00
124 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 5.00
125 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
126 INT191503 CD40LG Regulation of Gene_expression of F3 1 0.01 0.99 0.27 5.00
127 INT224458 TNF Positive_regulation of Gene_expression of Nfkb1 2 0.34 1.47 0.26 5.00
128 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
129 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 5.00
130 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24 5.00
131 INT186368 Il10 Negative_regulation of Gene_expression of Il12a 1 0.06 0.17 0.24 5.00
132 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 5.00
133 INT320153 Negative_regulation of Binding of IL6 and IL6R 1 0.02 0.37 0.24 5.00
134 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 5.00
135 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
136 INT261842 Pla2g6 Positive_regulation of Trpm8 1 0.03 0 0.23 5.00
137 INT221416 Binding of IL1B and Positive_regulation of NFKB2 1 0.02 0.88 0.23 5.00
138 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23 5.00
139 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 5.00
140 INT186374 Il13 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
141 INT186371 Il4 Negative_regulation of Positive_regulation of Il12a 1 0.06 0.3 0.23 5.00
142 INT186351 Binding of Gast and Stat1 3 0.16 2.77 0.22 5.00
143 INT186391 TNF Positive_regulation of Gene_expression of Il17a 1 0.03 0.38 0.22 5.00
144 INT186358 Il1 Positive_regulation of Gene_expression of Il17a 1 0.02 0.38 0.22 5.00
145 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21 5.00
146 INT186353 Binding of Il12a and Il1 1 0.21 0.38 0.2 5.00
147 INT252330 Binding of Cd36 and Cd47 2 0.10 0.72 0.19 5.00
148 INT345924 IL6 Regulation of Gene_expression of SPHAR 1 0.00 0.21 0.18 5.00
149 INT214380 Binding of IL1A and PRTN3 1 0.00 0.94 0.18 5.00
150 INT258399 Binding of IL6R and IL6ST 1 0.06 0.61 0.18 5.00
151 INT229928 Binding of C3 and CFH 1 0.07 1.35 0.17 5.00
152 INT252646 Binding of C6orf25 and SYT16 1 0.00 0.51 0.17 5.00
153 INT355829 Binding of SETBP1 and LIN9 1 0.00 0.06 0.17 5.00
154 INT229931 Negative_regulation of Binding of C3 and CFH 1 0.08 1.35 0.17 5.00
155 INT252326 Binding of Cx3cl1 and Klrk1 1 0.01 0.23 0.16 5.00
156 INT328004 Binding of CYBB and Gnb5 1 0.00 1.13 0.15 5.00
157 INT186380 Binding of SOAT1 and Stat6 1 0.02 0.11 0.15 5.00
158 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15 5.00
159 INT352417 Ccl2 Positive_regulation of Ccr5 1 0.06 0.26 0.14 5.00
160 INT186357 Binding of Irf1 and Stat6 1 0.04 2.09 0.14 5.00
161 INT186372 Binding of Irf1 and Stat1 1 0.04 2.06 0.14 5.00
162 INT352416 Ccl2 Positive_regulation of Ccr2 1 0.23 0.26 0.14 5.00
163 INT252336 Il2 Positive_regulation of Akt1 1 0.01 0 0.13 5.00
164 INT252327 Binding of Cd27 and Cd70 1 0.16 0.82 0.13 5.00
165 INT313913 Binding of Il23a and Il23r 1 0.24 0.43 0.13 5.00
166 INT313914 Binding of Il12a and Il23r 1 0.14 0.44 0.13 5.00
167 INT186379 Il12a Positive_regulation of Binding of IFNA1 1 0.03 0.07 0.12 5.00
168 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11 5.00
169 INT270201 Binding of CD28 and Cd86 1 0.10 0.58 0.08 5.00
170 INT250804 Binding of CCL4L1 and AP5M1 1 0.01 1.48 0.08 5.00
171 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08 5.00
172 INT252344 Binding of Cd40 and Mthfd1 2 0.16 0.34 0.08 5.00
173 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08 5.00
174 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08 5.00
175 INT270202 Binding of CD28 and Cd80 1 0.09 0.58 0.08 5.00
176 INT250801 Binding of AP5M1 and MAPKAP1 1 0.00 1.48 0.08 5.00
177 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08 5.00
178 INT186369 Negative_regulation of Binding of Gast and Stat1 1 0.04 1.04 0.07 5.00
179 INT186347 Binding of Irf2 and Rfc1 1 0.00 1.02 0.07 5.00
180 INT186361 Binding of Gast and Irf1 1 0.01 1.03 0.07 5.00
181 INT186364 Binding of Irf2 and Nos2 1 0.04 1.02 0.07 5.00
182 INT355828 Binding of MFGE8 and SEA 1 0.01 0.07 0.07 5.00
183 INT186860 MIR181A2HG Regulation of Cd86 1 0.02 1.05 0.07 5.00
184 INT186341 Binding of Irf1 and Irf2 1 0.02 1.04 0.07 5.00
185 INT186366 Binding of Stat1 and Stat6 1 0.12 1.04 0.07 5.00
186 INT186814 MIR181A2HG Regulation of ICAM1 1 0.01 1.05 0.07 5.00
187 INT252353 Regulation of Binding of LCP2 and Cd28 1 0.37 0 0.06 5.00
188 INT345925 IL6 Negative_regulation of Gene_expression of CYP1A2 1 0.13 0.18 0.06 5.00
189 INT186375 TNF Negative_regulation of Gene_expression of Il12b 1 0.03 0.78 0.06 5.00
190 INT252355 Binding of LCP2 and Cd28 1 0.30 0 0.06 5.00
191 INT270199 Icos Positive_regulation of Localization of Il10 1 0.03 0.63 0.06 5.00
192 INT229977 Binding of amd and Cfb 1 0.03 2.78 0.06 5.00
193 INT252338 Binding of Cd28 and Lat 1 0.30 0 0.06 5.00
194 INT229982 Binding of C3 and amd 1 0.02 1.14 0.06 5.00
195 INT252335 Regulation of Binding of Cd28 and Lat 1 0.37 0 0.06 5.00
196 INT229985 Binding of C2 and amd 1 0.01 1.89 0.06 5.00
197 INT186390 Binding of TNF and Irf1 1 0.02 0.99 0.05 5.00
198 INT186263 Binding of TNF and GORASP1 1 0.10 0.99 0.05 5.00
199 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05 5.00
200 INT186383 Binding of Nos2 and GORASP1 1 0.12 0.93 0.05 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Herpes Zoster. They are ordered first by their pain relevance and then by number of times they were reported in Herpes Zoster. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT278362 Negative_regulation of Hps5 2 0.21 15.71 4.44 100.00
2 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 100.00
3 INT278341 Positive_regulation of Hps5 8 0.38 5.47 0.62 100.00
4 INT31949 Negative_regulation of PIF1 5 0.05 4 1.38 100.00
5 INT278318 Gene_expression of Hps5 10 0.37 4.24 1.27 100.00
6 INT66585 Gene_expression of IER3 13 0.63 7.39 3.48 100.00
7 INT328986 Transcription of Hps5 1 0.04 1.82 0 100.00
8 INT67248 Gene_expression of TACC2 12 0.50 13.51 3.65 100.00
9 INT278331 Localization of Hps5 3 0.34 4.14 0.34 100.00
10 INT169076 Localization of MRVI1 1 0.68 1.94 0.35 100.00
11 INT60122 Negative_regulation of MADD 3 0.11 2.23 0.93 100.00
12 INT16236 Negative_regulation of CFH 31 0.57 19.59 3.36 100.00
13 INT55224 Gene_expression of DRGX 99 0.31 67.55 67.63 100.00
14 INT285836 Binding of ORF61 1 0.36 1.85 0 100.00
15 INT278328 Negative_regulation of Gene_expression of Hps5 1 0.20 1.1 0.39 100.00
16 INT328985 Negative_regulation of Negative_regulation of Hps5 1 0.03 1.07 0.39 100.00
17 INT154821 Negative_regulation of MOS 1 0.41 1.29 0.28 100.00
18 INT191528 Positive_regulation of Localization of LPA 1 0.05 3.59 0.83 100.00
19 INT153814 Localization of LPA 19 0.65 18.25 7.68 100.00
20 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.98
21 INT285834 Gene_expression of ORF63 1 0.02 4.52 0 99.98
22 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 99.98
23 INT67589 Gene_expression of MT1E 8 0.51 7.52 1.09 99.98
24 INT185394 Binding of PVRL1 5 0.14 2.94 0.09 99.92
25 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0 99.92
26 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 99.88
27 INT68369 Transcription of TNC 13 0.72 8.69 4.42 99.82
28 INT266166 Negative_regulation of RPA1 2 0.08 1.65 0.03 99.78
29 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 99.76
30 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 99.76
31 INT318764 Regulation of CTTNBP2 1 0.03 0.78 0 99.70
32 INT318743 Regulation of Transcription of ORF61 1 0.03 0.78 0 99.70
33 INT318765 Regulation of Transcription of CTTNBP2 1 0.04 0.78 0 99.70
34 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 99.66
35 INT116426 Gene_expression of Pdpn 7 0.58 2.75 0.29 99.56
36 INT158295 Transcription of CD8A 11 0.53 4.02 0.7 99.54
37 INT281221 Transcription of ORF61 2 0.05 1.51 0.06 99.52
38 INT318766 Transcription of CTTNBP2 1 0.07 0.78 0 99.52
39 INT152221 Gene_expression of PRODH 7 0.58 11.03 0.79 99.50
40 INT232187 Gene_expression of DFNB31 1 0.06 1.32 0.29 99.36
41 INT114017 Gene_expression of CD200 10 0.75 2.38 0.88 99.36
42 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 99.32
43 INT96845 Positive_regulation of Regulation of Serpinc1 1 0.18 1.78 1.22 99.20
44 INT57494 Positive_regulation of Positive_regulation of Serpinc1 3 0.26 1.67 1.19 99.20
45 INT200435 Binding of polymerase 6 0.16 5.56 0.47 99.20
46 INT20200 Positive_regulation of Serpinc1 25 0.68 17.08 4.98 99.16
47 INT14396 Regulation of Serpinc1 5 0.19 3.16 1.16 99.16
48 INT96844 Regulation of Positive_regulation of Serpinc1 1 0.10 0.89 0.61 99.16
49 INT39634 Regulation of Gene_expression of F2 4 0.22 1.72 1.31 99.16
50 INT2270 Positive_regulation of Gene_expression of F2 6 0.21 4.23 1.26 99.16
51 INT27703 Negative_regulation of Pol1 2 0.52 2.08 0.26 99.14
52 INT23402 Binding of HLA-DOA 74 0.48 52.01 10.89 99.12
53 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.04
54 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41 99.02
55 INT7531 Positive_regulation of Eef1a1 29 0.62 8.16 15.41 99.02
56 INT4868 Gene_expression of GAL 75 0.78 22.23 29.02 99.00
57 INT51946 Gene_expression of Apold1 13 0.39 3.56 6.08 98.96
58 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.94
59 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 98.86
60 INT10016 Negative_regulation of CD8A 81 0.42 56.68 13.15 98.80
61 INT106781 Negative_regulation of Ylpm1 5 0.49 5.36 2.95 98.76
62 INT14301 Binding of CSF2 82 0.48 67.95 8.98 98.72
63 INT214 Localization of AVP 370 0.81 208.51 91.09 98.70
64 INT70933 Regulation of SEPHS1 3 0.37 2.56 0.81 98.60
65 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 98.60
66 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 98.48
67 INT8634 Gene_expression of Nfasc 23 0.68 9.16 14.96 98.44
68 INT81100 Binding of Pol1 1 0.08 0.71 0.03 98.32
69 INT81103 Phosphorylation of Tk1 4 0.40 3.07 0.87 98.20
70 INT8959 Binding of Gnb5 17 0.40 31.38 5.1 98.20
71 INT107575 Positive_regulation of Gene_expression of Atf3 25 0.69 27.37 14.55 98.16
72 INT107576 Gene_expression of Atf3 114 0.78 72.42 38.64 98.16
73 INT11161 Gene_expression of HLA-DRB1 121 0.78 75.33 20.96 98.16
74 INT14854 Regulation of Gene_expression of HLA-DRB1 10 0.39 5.27 2.19 98.16
75 INT221269 Binding of BRCA1 14 0.40 31.77 2.7 98.16
76 INT11235 Positive_regulation of IFNA2 27 0.69 15.32 2.57 97.92
77 INT19768 Negative_regulation of LAMC2 11 0.57 10.54 5.32 97.92
78 INT145856 Positive_regulation of GZMB 3 0.10 2.64 0.15 97.80
79 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 97.72
80 INT5870 Negative_regulation of IFNA2 20 0.49 12 4.3 97.66
81 INT67590 Gene_expression of RDBP 9 0.51 5.17 1.1 97.52
82 INT154730 Regulation of Slc6a5 3 0.43 1.91 1.56 97.44
83 INT144689 Regulation of RCT 49 0.53 25.91 9.6 97.32
84 INT53222 Regulation of Negative_regulation of C5AR1 1 0.26 0.61 0.13 97.32
85 INT101859 Gene_expression of MCF2 34 0.49 19.45 1.51 97.28
86 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 97.16
87 INT142597 Regulation of Binding of Apoe 1 0.34 2.21 0.8 97.06
88 INT72141 Binding of Apoe 11 0.37 10.91 3.27 97.06
89 INT116552 Positive_regulation of Localization of Nfkb1 16 0.61 12.7 7.74 97.04
90 INT78480 Localization of Nfkb1 39 0.80 23.14 13.64 96.84
91 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 96.76
92 INT23174 Gene_expression of NLRP3 51 0.72 35.49 6.47 96.68
93 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 96.64
94 INT42277 Gene_expression of GIPC1 6 0.25 2.06 1.61 96.48
95 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 96.44
96 INT45109 Binding of C5AR1 10 0.37 5.77 2.69 96.40
97 INT17692 Negative_regulation of C5AR1 5 0.57 2.99 1.04 96.40
98 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 96.38
99 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 96.16
100 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 96.12
101 INT14501 Gene_expression of CST3 28 0.75 25.77 5.16 95.96
102 INT94876 Gene_expression of LY6G6E 1 0.01 1.82 0.48 95.68
103 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 95.68
104 INT288676 Negative_regulation of CREM 3 0.18 1.34 0.96 95.60
105 INT16404 Regulation of CD4 54 0.61 33.05 10.29 95.32
106 INT252662 Binding of SYT16 1 0.01 8.05 0.45 95.28
107 INT285835 Localization of ORF63 1 0.02 1.39 0 94.96
108 INT92349 Positive_regulation of MAX 3 0.41 1.46 0.53 94.96
109 INT158 Localization of Prl 2431 0.81 378.96 952.2 94.40
110 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 94.40
111 INT318767 Gene_expression of WDR19 1 0.05 0.68 0 94.04
112 INT11072 Binding of HELT 4 0.31 3.81 0.89 94.00
113 INT107272 Binding of GPA33 1 0.24 1.37 0.76 94.00
114 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 94.00
115 INT32517 Positive_regulation of LRPAP1 13 0.49 7.4 3.44 93.80
116 INT143996 Positive_regulation of CISH 28 0.49 17.31 7.17 93.72
117 INT48248 Gene_expression of Scn10a 38 0.78 19.3 25.05 93.68
118 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 93.34
119 INT56651 Binding of HLA-DRB1 58 0.48 52.25 13.68 93.20
120 INT192684 Negative_regulation of vs 15 0.19 9.18 1.75 93.08
121 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 92.76
122 INT233 Binding of Gast 31 0.42 17.07 5.21 92.56
123 INT315796 Positive_regulation of Gene_expression of Tst 1 0.32 5 0 92.48
124 INT47950 Negative_regulation of ELOVL1 15 0.41 20.33 1.41 92.40
125 INT130793 Positive_regulation of Gene_expression of Nfasc 1 0.02 1.76 0.99 92.24
126 INT8380 Positive_regulation of Gene_expression of Npy 49 0.70 19.62 24.13 92.24
127 INT144702 Gene_expression of Tst 19 0.68 12.87 4.04 92.24
128 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 91.84
129 INT81101 Regulation of Phosphorylation of Tk1 1 0.02 0.77 0.07 91.60
130 INT35368 Positive_regulation of Tk1 9 0.53 4.68 1.81 91.08
131 INT81102 Positive_regulation of Positive_regulation of Tk1 2 0.35 1.45 0.61 91.08
132 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 90.84
133 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 90.84
134 INT93908 Negative_regulation of Dpyd 9 0.45 3.19 0.78 90.80
135 INT95904 Gene_expression of CD27 45 0.76 26.17 1.93 90.56
136 INT88053 Gene_expression of IGHD@ 2 0.61 4.41 0.17 90.56
137 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 90.56
138 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 90.56
139 INT236839 Positive_regulation of CXCL13 14 0.44 19.27 5.81 90.16
140 INT81280 Binding of Atp9a 20 0.47 11.14 3.24 90.08
141 INT79270 Gene_expression of MKI67 113 0.77 63.52 3.38 89.80
142 INT214558 Localization of IGHD@ 2 0.10 2.89 0 89.60
143 INT163189 Localization of CD27 7 0.74 5.31 0.18 89.60
144 INT161382 Localization of KRT20 25 0.61 12.97 2.13 89.60
145 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 89.52
146 INT250811 Regulation of AP5M1 1 0.01 2.45 0.07 88.84
147 INT264881 Localization of CXCL13 4 0.42 9.52 1.85 88.76
148 INT127428 Negative_regulation of Ptger1 8 0.42 5.26 4.15 88.68
149 INT127427 Negative_regulation of Ptgdr 1 0.17 1.66 1.12 88.68
150 INT10019 Binding of CD8A 57 0.36 31.49 10.08 88.64
151 INT53196 Binding of Cd4 44 0.47 27.28 5.85 88.64
152 INT182240 Gene_expression of CXCL13 25 0.59 22.77 11.96 88.40
153 INT180535 Gene_expression of BPI 4 0.52 3.61 0.91 88.12
154 INT15814 Positive_regulation of Localization of CALCB 4 0.20 2.49 3.82 88.08
155 INT15812 Localization of CALCB 10 0.30 8.77 6.36 88.08
156 INT11244 Transcription of CALCA 21 0.69 3.61 12.27 88.00
157 INT326917 Gene_expression of Olfr53 1 0.01 11.96 0.67 87.92
158 INT57549 Gene_expression of GNPTAB 49 0.65 57.5 9.05 87.92
159 INT320680 Regulation of Gene_expression of GNPTAB 2 0.32 2.14 0.09 87.92
160 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 87.64
161 INT49149 Transcription of GAL 9 0.67 2.18 5.39 87.60
162 INT285839 Gene_expression of C12orf61 1 0.01 1.45 0 87.48
163 INT250817 Binding of AP5M1 2 0.01 2.72 0.15 87.48
164 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 87.00
165 INT55486 Negative_regulation of Positive_regulation of LBR 1 0.41 1.07 0.08 86.64
166 INT48106 Positive_regulation of LBR 11 0.49 5.14 2.86 86.64
167 INT56816 Gene_expression of Tk1 7 0.59 4.92 0.9 86.56
168 INT195203 Binding of Tenc1 14 0.32 13.97 8.28 86.08
169 INT55904 Binding of Padi4 2 0.02 1.63 0.26 86.08
170 INT2405 Negative_regulation of SGCA 15 0.57 6.04 2.45 86.00
171 INT10870 Regulation of IgG 67 0.59 43.27 12.74 86.00
172 INT4866 Positive_regulation of GAL 32 0.67 13.02 16.16 85.84
173 INT174557 Negative_regulation of Gene_expression of Cd28 7 0.43 4.42 1.2 85.60
174 INT94125 Gene_expression of Cd28 38 0.67 21.73 7.75 85.40
175 INT74631 Gene_expression of UBXN11 19 0.75 6.11 0.57 84.88
176 INT191527 Positive_regulation of Gene_expression of NLRP3 6 0.50 8.65 1.15 84.68
177 INT287483 Negative_regulation of Localization of IGH@ 1 0.15 1.3 0.08 84.68
178 INT6852 Localization of TNF 883 0.81 705.95 270.84 84.60
179 INT70529 Positive_regulation of Cish 16 0.59 14.43 3.8 84.52
180 INT140411 Gene_expression of Nqo1 45 0.60 62.35 8.7 84.28
181 INT209607 Localization of IGH@ 3 0.34 2.5 0.22 84.28
182 INT14887 Gene_expression of Mbp 55 0.75 36.13 16.11 83.68
183 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 83.48
184 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 83.48
185 INT64175 Negative_regulation of Gene_expression of CPOX 66 0.38 39.64 23.07 83.48
186 INT81099 Positive_regulation of Pol1 1 0.09 1.29 0.13 83.44
187 INT188844 Gene_expression of AES 44 0.58 33.94 5.85 83.36
188 INT89594 Gene_expression of Ccl5 44 0.54 24.08 18.62 83.28
189 INT11266 Positive_regulation of UMOD 2 0.43 1.25 1.16 82.64
190 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 82.40
191 INT14888 Gene_expression of PSS 9 0.66 6.9 1.65 82.28
192 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 82.24
193 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 82.16
194 INT174550 Negative_regulation of Cd28 7 0.33 4.7 1.06 82.08
195 INT174240 Negative_regulation of TYMS 12 0.57 6.35 1.82 81.68
196 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 81.52
197 INT26705 Transcription of ADRA1D 6 0.67 3.99 2.74 81.52
198 INT7898 Gene_expression of Homer1 123 0.78 31.52 53.67 80.96
199 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 80.52
200 INT84704 Positive_regulation of Nqo1 18 0.70 18.64 5.65 80.40
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