D:Homocystinuria

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Disease Term
Synonyms CYSTATHIONINE BETA SYNTHASE DEFICIENCY DISEASE, Cystathionine Synthase Deficiency, DEFICIENCY DISEASE CYSTATHIONINE BETA SYNTHASE
Documents 47
Hot Single Events 16
Hot Interactions 0

Single Events

The table below shows the top 200 pain related interactions that have been reported for Homocystinuria. They are ordered first by their pain relevance and then by number of times they were reported in Homocystinuria. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 99.54
2 INT111345 Negative_regulation of Cbs 2 0.30 2.82 0.36 98.98
3 INT70913 Gene_expression of MTR 2 0.12 0.44 0.21 98.68
4 INT9217 Negative_regulation of MTR 17 0.58 1.13 1.32 98.36
5 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 96.32
6 INT30443 Positive_regulation of AIS 30 0.54 22.59 7.2 95.84
7 INT255313 Positive_regulation of Positive_regulation of AIS 2 0.04 3.83 0.55 95.84
8 INT1928 Negative_regulation of Lpl 18 0.51 11.22 2.49 90.52
9 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 89.72
10 INT38299 Negative_regulation of FCGR2C 6 0.21 3.92 0.52 89.00
11 INT39512 Negative_regulation of TRAP 22 0.56 8.18 4.76 86.88
12 INT101556 Regulation of Nt5e 5 0.40 2.81 5.2 84.12
13 INT119485 Regulation of Entpd1 1 0.27 1.26 0.93 84.12
14 INT21545 Regulation of DNAH8 22 0.59 8.67 6.48 81.28
15 INT151522 Binding of NSD1 2 0.37 4.28 0.09 80.60
16 INT40878 Localization of UTP14C 2 0.38 0.24 0.8 80.56
17 INT14447 Localization of F2 20 0.79 12.77 2.67 78.36
18 INT214056 Negative_regulation of NSD1 3 0.43 3.44 0.09 74.00
19 INT214055 Gene_expression of NSD1 8 0.67 4.46 0 73.52
20 INT2871 Positive_regulation of Comt 9 0.50 2.8 4.78 72.28
21 INT329023 Positive_regulation of Cbs 1 0.18 1.36 0.07 71.28
22 INT97078 Positive_regulation of Entpd1 16 0.64 8.54 4.49 66.36
23 INT101555 Positive_regulation of Nt5e 5 0.45 2.91 1.4 65.76
24 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07 63.88
25 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 63.88
26 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 63.88
27 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 63.52
28 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 63.52
29 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 63.52
30 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 53.44
31 INT519 Negative_regulation of Comt 52 0.59 17.65 20.39 47.20
32 INT147583 Gene_expression of AIS 82 0.58 48.7 7.11 37.12
33 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
34 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
35 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48 5.00
36 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 5.00
37 INT520 Binding of Comt 24 0.48 8.98 12.21 5.00
38 INT73431 Positive_regulation of Nos3 82 0.65 53.22 11.61 5.00
39 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27 5.00
40 INT20664 Binding of ACE 60 0.48 35.27 9.16 5.00
41 INT15887 Gene_expression of Nbr1 39 0.77 23.91 7.34 5.00
42 INT63042 Binding of Apoe 59 0.48 31.23 5.88 5.00
43 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31 5.00
44 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 5.00
45 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 5.00
46 INT10828 Regulation of Apob 7 0.39 7.55 0.83 5.00
47 INT161085 Positive_regulation of Notch3 4 0.41 4.36 0.27 5.00
48 INT287448 Gene_expression of Tagln 6 0.65 3.73 0.16 5.00
49 INT287445 Regulation of Tagln 2 0.29 2.59 0.08 5.00
50 INT299147 Positive_regulation of Gene_expression of Ren2 2 0.24 1.51 0 5.00
51 INT299151 Gene_expression of Ren2 3 0.37 1.96 0 5.00
52 INT329021 Regulation of Gene_expression of Notch3 1 0.09 2.04 0 5.00
53 INT329022 Gene_expression of Notch3 1 0.27 2.04 0 5.00
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