D:Hydatidiform Mole

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Disease Term
Synonyms Complete Hydatidiform Mole, Complete Hydatidiform Moles, Hydatid Mole, Hydatid Moles, Hydatidiform Mole Complete, Hydatidiform Mole Partial, Hydatidiform Moles, Hydatidiform Moles Complete, Hydatidiform Moles Partial, Molar Pregnancies, Molar Pregnancy
Documents 53
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hydatidiform Mole. They are ordered first by their relevance to Hydatidiform Mole and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67 5.00
2 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
3 INT240620 Binding of INS and SHBG 4 0.12 3.35 0.15 5.00
4 INT186243 IL36RN Positive_regulation of B4GALNT1 1 0.00 0.43 0.12 5.00
5 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 5.00
6 INT186246 Binding of CAT and SCN5A 1 0.03 0.47 0.1 5.00
7 INT186242 Binding of ALB and SCN5A 1 0.04 0.36 0.1 5.00
8 INT186245 Binding of AGRP and CAT 1 0.02 0.53 0.1 5.00
9 INT186244 Binding of AGRP and ALB 1 0.03 0.53 0.1 5.00
10 INT350106 Binding of SLC4A3 and SLC4A1 1 0.13 2.78 0.09 5.00
11 INT251469 INS Negative_regulation of Gene_expression of SHBG 2 0.11 4.11 0.08 5.00
12 INT266082 PROC Regulation of Localization of VEGFA 1 0.00 0.84 0.05 5.00
13 INT251468 Binding of APOE and DBT 1 0.03 1.18 0.05 5.00
14 INT266078 VEGFA Positive_regulation of DBI 1 0.10 0.45 0.04 5.00
15 INT266074 LGALS1 Regulation of Gene_expression of PAEP 1 0.14 0.43 0.03 5.00
16 INT266075 LIF Regulation of Gene_expression of PAEP 1 0.19 0.43 0.03 5.00
17 INT266070 LIF Regulation of Gene_expression of PAPPA 1 0.35 0.49 0.03 5.00
18 INT186249 Binding of ROS1 and SCN5A 1 0.09 0.73 0.03 5.00
19 INT266072 LGALS1 Regulation of Gene_expression of LIF 1 0.17 0.43 0.03 5.00
20 INT266067 PAPPA Regulation of Gene_expression of LIF 1 0.35 0.49 0.03 5.00
21 INT266076 LIF Regulation of Gene_expression of LGALS1 1 0.17 0.43 0.03 5.00
22 INT266081 PAPPA Regulation of Gene_expression of LGALS1 1 0.24 0.49 0.03 5.00
23 INT266077 LGALS1 Regulation of Gene_expression of PAPPA 1 0.24 0.49 0.03 5.00
24 INT266073 PAPPA Regulation of Gene_expression of PAEP 1 0.27 0.49 0.03 5.00
25 INT186248 NR5A1 Positive_regulation of Transcription of STAR 1 0.01 0.21 0 5.00
26 INT186239 Binding of ROS1 and Positive_regulation of PDE2A 1 0.00 0 0 5.00
27 INT186241 Gene_expression of ROS1 Positive_regulation of PDE2A 1 0.00 0 0 5.00
28 INT266080 Binding of PAPPA and MUC16 1 0.40 0.74 0 5.00
29 INT266068 Binding of CHKB and MUC16 1 0.22 0.74 0 5.00
30 INT186247 CGA Regulation of Gene_expression of SOD1 1 0.01 0.35 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hydatidiform Mole. They are ordered first by their pain relevance and then by number of times they were reported in Hydatidiform Mole. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1793 Localization of CGA 379 0.81 67.38 114.69 99.78
2 INT1792 Positive_regulation of CGA 123 0.70 64.73 20.79 99.32
3 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 99.04
4 INT57029 Positive_regulation of HEXB 6 0.40 4.52 0.55 95.20
5 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 94.56
6 INT10675 Gene_expression of DBI 28 0.67 19.74 6.07 94.52
7 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 85.48
8 INT100886 Gene_expression of GCLC 16 0.76 5.63 2.29 82.64
9 INT100892 Positive_regulation of GCLC 8 0.68 3.44 1.08 82.64
10 INT186262 Transcription of GCLC 3 0.23 1.19 0 82.64
11 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 80.56
12 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 79.88
13 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 79.88
14 INT23352 Negative_regulation of A2M 10 0.33 8.35 2.16 79.12
15 INT425 Localization of PRL 455 0.81 189.64 144.8 78.96
16 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 77.44
17 INT23348 Negative_regulation of Serpinf2 8 0.38 3.02 0.65 75.60
18 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 69.68
19 INT10565 Gene_expression of MRXS5 94 0.53 37.35 19.08 63.52
20 INT25463 Negative_regulation of Gene_expression of MRXS5 7 0.38 4.75 2.12 63.52
21 INT159543 Localization of SOD1 29 0.75 8.62 1.06 54.24
22 INT159542 Localization of SOD2 5 0.80 1.91 0.36 54.24
23 INT10676 Negative_regulation of DBI 10 0.37 7 3.65 32.64
24 INT8545 Negative_regulation of MUC16 19 0.57 15.96 2.81 32.16
25 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 25.00
26 INT11728 Binding of NUPL2 3 0.47 3.28 0.42 23.36
27 INT70449 Binding of SLC4A1 5 0.36 5.1 0.38 22.56
28 INT283503 Binding of SLC4A2 3 0.09 3.39 0.19 21.76
29 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 18.28
30 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 7.52
31 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 7.52
32 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
33 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
34 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
35 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
36 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
37 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
38 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
39 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
40 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
41 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
42 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
43 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
44 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
45 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
46 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 5.00
47 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6 5.00
48 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69 5.00
49 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
50 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
51 INT651 Positive_regulation of PTGS1 93 0.69 37.27 29.18 5.00
52 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
53 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
54 INT70504 Regulation of Gene_expression of NOS1 30 0.51 21.72 21.72 5.00
55 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 5.00
56 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
57 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 5.00
58 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
59 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 5.00
60 INT69435 Negative_regulation of ROS1 74 0.51 50.38 13.71 5.00
61 INT73594 Positive_regulation of Gene_expression of ISYNA1 61 0.55 31.35 13.45 5.00
62 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
63 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48 5.00
64 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 5.00
65 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 5.00
66 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
67 INT112003 Localization of ROS1 94 0.73 66.32 12.16 5.00
68 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
69 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 5.00
70 INT13240 Gene_expression of TF 94 0.76 57.81 10.99 5.00
71 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 5.00
72 INT22132 Positive_regulation of CAT 41 0.67 18.64 10.67 5.00
73 INT86361 Positive_regulation of Positive_regulation of NOS1 39 0.53 18.93 10.42 5.00
74 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
75 INT3846 Positive_regulation of GSR 60 0.50 35.16 9.37 5.00
76 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 5.00
77 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 5.00
78 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 5.00
79 INT48908 Transcription of NOS1 27 0.55 13.46 8.39 5.00
80 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41 5.00
81 INT6906 Negative_regulation of SCN5A 64 0.43 20.64 7.3 5.00
82 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 5.00
83 INT4228 Gene_expression of CAT 50 0.75 20.62 7.18 5.00
84 INT79062 Gene_expression of B4GALNT1 42 0.14 18.89 6.98 5.00
85 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
86 INT2111 Gene_expression of LIF 34 0.77 16.82 6.76 5.00
87 INT24907 Gene_expression of PAPPA 42 0.75 28.32 6.63 5.00
88 INT29561 Binding of GSTM1 35 0.48 25.86 6.24 5.00
89 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
90 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 5.00
91 INT39047 Gene_expression of PGF 34 0.78 17.48 6 5.00
92 INT48911 Binding of NOS1 24 0.40 11.21 5.89 5.00
93 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 5.00
94 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6 5.00
95 INT30209 Localization of SCN5A 24 0.72 7.95 5.35 5.00
96 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
97 INT47662 Localization of CHKB 34 0.81 22.63 5.14 5.00
98 INT174193 Gene_expression of LILRA3 20 0.28 12.65 5.1 5.00
99 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 5.00
100 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 5.00
101 INT8340 Negative_regulation of SHBG 49 0.57 35.96 4.73 5.00
102 INT103155 Gene_expression of KDR 78 0.66 50.53 4.38 5.00
103 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 5.00
104 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06 5.00
105 INT117614 Positive_regulation of PAPPA 18 0.67 11.9 3.76 5.00
106 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 5.00
107 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 5.00
108 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 5.00
109 INT9549 Regulation of CHKB 25 0.47 13.61 3.2 5.00
110 INT140555 Positive_regulation of Localization of ROS1 29 0.55 23.82 3.14 5.00
111 INT22402 Positive_regulation of DBI 17 0.59 7.77 2.91 5.00
112 INT172678 Gene_expression of NUPL2 20 0.75 5.06 2.85 5.00
113 INT24904 Negative_regulation of PAPPA 13 0.57 9.93 2.74 5.00
114 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62 5.00
115 INT24902 Gene_expression of SP1 17 0.71 8.11 2.58 5.00
116 INT172808 Positive_regulation of Positive_regulation of ROS1 35 0.40 31.39 2.27 5.00
117 INT22404 Regulation of DBI 7 0.39 3.66 2.24 5.00
118 INT96856 Localization of NOSTRIN 8 0.49 6.39 2.19 5.00
119 INT62331 Gene_expression of TNFRSF8 26 0.72 17.75 2.08 5.00
120 INT82166 Regulation of NOS3 14 0.54 7.57 2.08 5.00
121 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99 5.00
122 INT2982 Positive_regulation of Gene_expression of CGA 17 0.59 9.08 1.99 5.00
123 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92 5.00
124 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92 5.00
125 INT20630 Positive_regulation of Gene_expression of CHKB 19 0.47 15.79 1.85 5.00
126 INT24906 Negative_regulation of SP1 8 0.40 4.48 1.77 5.00
127 INT192684 Negative_regulation of vs 15 0.19 9.18 1.75 5.00
128 INT25499 Localization of DBI 14 0.52 5.31 1.7 5.00
129 INT117330 Negative_regulation of Binding of ROS1 13 0.37 8.33 1.67 5.00
130 INT110569 Gene_expression of XDH 31 0.75 18.35 1.34 5.00
131 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34 5.00
132 INT42116 Positive_regulation of ME1 5 0.05 1.56 1.33 5.00
133 INT3486 Positive_regulation of Regulation of INS 9 0.47 5.65 1.15 5.00
134 INT3046 Gene_expression of LGALS1 20 0.75 12.48 1.11 5.00
135 INT186251 Negative_regulation of Gene_expression of B4GALNT1 5 0.07 1.84 1.07 5.00
136 INT189748 Transcription of CHKB 6 0.36 1.6 1.07 5.00
137 INT2981 Negative_regulation of Gene_expression of CGA 14 0.42 3.41 1.05 5.00
138 INT104908 Binding of B4GALNT1 7 0.05 4.62 0.82 5.00
139 INT20765 Negative_regulation of INHBA 6 0.34 1.91 0.77 5.00
140 INT70530 Binding of NPR1 3 0.17 0.71 0.65 5.00
141 INT10677 Positive_regulation of Gene_expression of DBI 3 0.24 6.2 0.64 5.00
142 INT81799 Negative_regulation of Binding of AGRP 5 0.42 1.13 0.63 5.00
143 INT174274 Positive_regulation of Localization of NOSTRIN 2 0.09 2.35 0.58 5.00
144 INT186260 Positive_regulation of Binding of B4GALNT1 1 0.06 0.93 0.56 5.00
145 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55 5.00
146 INT24903 Negative_regulation of Gene_expression of PAPPA 6 0.42 2.98 0.52 5.00
147 INT20766 Positive_regulation of INHBA 4 0.66 5.66 0.48 5.00
148 INT7067 Negative_regulation of Gene_expression of SHBG 7 0.41 5.08 0.48 5.00
149 INT158019 Positive_regulation of Gene_expression of FLT1 20 0.68 9.73 0.44 5.00
150 INT2110 Localization of LIF 5 0.73 1.59 0.44 5.00
151 INT96816 Regulation of APOE 8 0.45 6.62 0.44 5.00
152 INT131773 Regulation of KDR 12 0.49 12.01 0.39 5.00
153 INT111489 Gene_expression of HAS3 3 0.61 1.91 0.39 5.00
154 INT189750 Negative_regulation of Positive_regulation of CHKB 4 0.26 2.36 0.38 5.00
155 INT39715 Negative_regulation of PGF 3 0.41 1.22 0.31 5.00
156 INT158990 Localization of PAPPA 3 0.78 2.48 0.27 5.00
157 INT212762 Regulation of FLT1 21 0.58 2.95 0.26 5.00
158 INT129399 Transcription of SOD1 6 0.66 3.08 0.25 5.00
159 INT186256 Transcription of ROS1 4 0.39 2.37 0.25 5.00
160 INT58857 Positive_regulation of Positive_regulation of CHKB 5 0.43 2.77 0.19 5.00
161 INT204721 Localization of FLT1 30 0.73 4.64 0.15 5.00
162 INT266086 Negative_regulation of Gene_expression of DBI 1 0.07 1.16 0.1 5.00
163 INT110568 Positive_regulation of Gene_expression of XDH 7 0.49 5.14 0.09 5.00
164 INT266090 Transcription of DBI 1 0.12 1.18 0.08 5.00
165 INT247569 Positive_regulation of Regulation of VEGFA 6 0.48 4.15 0.07 5.00
166 INT266087 Positive_regulation of Positive_regulation of DBI 1 0.09 1.35 0.06 5.00
167 INT186259 Gene_expression of NR5A1 2 0.64 2.19 0.05 5.00
168 INT266092 Localization of HAP1 2 0.67 0.44 0.03 5.00
169 INT186257 Positive_regulation of Transcription of ROS1 2 0.34 0.1 0.03 5.00
170 INT266091 Positive_regulation of Localization of HAP1 2 0.45 0.44 0.03 5.00
171 INT266088 Positive_regulation of Localization of LIF 1 0.34 0.45 0.03 5.00
172 INT266085 Negative_regulation of Positive_regulation of DBI 1 0.07 1.09 0.03 5.00
173 INT266089 Positive_regulation of Localization of PAPPA 1 0.49 0.44 0.03 5.00
174 INT251463 Negative_regulation of Inha 1 0.41 0.68 0.03 5.00
175 INT186261 Gene_expression of ME1 3 0.10 2.87 0 5.00
176 INT251465 Positive_regulation of Inha 1 0.67 1.8 0 5.00
177 INT186254 Transcription of STAR 1 0.02 0.2 0 5.00
178 INT204193 Negative_regulation of TRIT1 1 0.05 0.27 0 5.00
179 INT251471 Gene_expression of LGALS13 1 0.10 1.02 0 5.00
180 INT186253 Binding of NR5A1 1 0.17 0.16 0 5.00
181 INT251472 Positive_regulation of Gene_expression of LGALS13 1 0.08 0.48 0 5.00
182 INT186258 Localization of NR5A1 5 0.77 3.62 0 5.00
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