D:Hydrocele

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Disease Term
Synonyms Hydrocele Sac, Hydroceles
Documents 181
Hot Single Events 21
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hydrocele. They are ordered first by their relevance to Hydrocele and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 71.68
2 INT197097 IL1B Regulation of FLT4 1 0.03 0.66 0.19 68.00
3 INT197098 TNF Regulation of FLT4 1 0.14 0.66 0.19 68.00
4 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 65.76
5 INT175727 IL1B Regulation of VEGFA 2 0.04 0.7 0.19 65.76
6 INT197095 IL1B Regulation of Positive_regulation of TNF 1 0.01 0.64 0.19 63.60
7 INT197093 TNF Regulation of Positive_regulation of IL1B 1 0.01 0.64 0.19 63.60
8 INT313687 Binding of BCR and IFIH1 1 0.09 0.23 0 40.84
9 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 33.92
10 INT197096 VEGFA Positive_regulation of FLT4 1 0.04 1.43 0 16.92
11 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49 5.00
12 INT197099 Negative_regulation of Binding of FLT4 and VEGFA 1 0.04 1.04 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hydrocele. They are ordered first by their pain relevance and then by number of times they were reported in Hydrocele. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.30
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.20
3 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 98.92
4 INT297919 Negative_regulation of Gene_expression of LTF 2 0.09 3.27 0.79 98.92
5 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 98.64
6 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 98.54
7 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 98.48
8 INT103020 Gene_expression of SGCA 22 0.56 14.29 2.75 98.48
9 INT91106 Negative_regulation of LTF 9 0.51 5.73 1.09 98.40
10 INT4988 Gene_expression of KRT1 64 0.77 43.4 4.12 97.60
11 INT196007 Positive_regulation of FLT4 2 0.56 5.44 0.08 93.52
12 INT147113 Binding of LTF 14 0.29 18.24 0.98 93.32
13 INT99524 Gene_expression of IFIH1 34 0.64 23.38 2.24 92.48
14 INT152643 Positive_regulation of Gene_expression of IFIH1 5 0.42 5.2 0.28 92.48
15 INT188776 Positive_regulation of IFIH1 10 0.23 9.93 0.35 90.60
16 INT67389 Positive_regulation of SGCA 7 0.45 2.92 0.69 85.84
17 INT188176 Positive_regulation of Gene_expression of CDH5 3 0.32 0.75 0.07 85.84
18 INT188173 Gene_expression of CDH5 14 0.49 3.17 0.44 85.44
19 INT197105 Negative_regulation of FLT4 13 0.42 11.48 0.92 84.80
20 INT288384 Binding of CHIT1 2 0.15 2.04 0.22 83.04
21 INT297921 Regulation of Gene_expression of LTF 2 0.10 3.11 0.37 82.40
22 INT188775 Binding of IFIH1 11 0.16 12.4 0.61 79.92
23 INT313688 Regulation of IFIH1 3 0.19 4.2 0.48 79.48
24 INT183668 Binding of SGCA 15 0.36 9.86 2.42 76.72
25 INT80007 Transcription of GRIN1 5 0.67 2.36 3.26 74.80
26 INT241797 Gene_expression of CHIT1 10 0.24 9.75 0.69 73.76
27 INT288383 Regulation of Gene_expression of CHIT1 1 0.18 2.99 0 73.76
28 INT181790 Gene_expression of FLT4 13 0.72 11.73 0.56 73.52
29 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 72.88
30 INT32344 Localization of LTF 30 0.80 15.28 10.09 71.40
31 INT26585 Gene_expression of Vim 117 0.77 39.97 6 68.68
32 INT196006 Regulation of FLT4 2 0.25 2.24 0.27 68.00
33 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 61.52
34 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 61.52
35 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 60.40
36 INT68960 Gene_expression of Ptger4 42 0.67 15.75 9.64 60.20
37 INT192676 Binding of PTEN 14 0.46 10.58 3.06 59.04
38 INT148271 Regulation of SGCA 10 0.37 5.89 0.86 57.12
39 INT204254 Localization of KIT 8 0.73 6.78 0.61 54.96
40 INT4144 Gene_expression of SHBG 64 0.68 39.94 6.08 47.84
41 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 47.60
42 INT35254 Negative_regulation of SERPINB1 22 0.48 11.42 4.7 46.00
43 INT37193 Negative_regulation of BDNF-AS 21 0.37 15.06 3.12 46.00
44 INT247403 Negative_regulation of Gene_expression of SERPINB1 1 0.01 0.77 0 46.00
45 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 45.36
46 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 45.36
47 INT154235 Gene_expression of KPNA1 2 0.78 1.77 0.1 37.44
48 INT281255 Positive_regulation of Negative_regulation of CDY1 1 0.28 1.64 0 36.20
49 INT281257 Positive_regulation of Positive_regulation of DAZ1 1 0.16 1.58 0 36.20
50 INT281252 Positive_regulation of DAZ1 1 0.16 1.56 0 34.28
51 INT47625 Negative_regulation of IFIH1 4 0.51 1.68 0.39 33.84
52 INT281258 Negative_regulation of CDY1 1 0.23 1.61 0 33.48
53 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 28.12
54 INT23598 Binding of SCN5A 32 0.40 16 5.35 27.08
55 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 24.00
56 INT20611 Gene_expression of Asap1 55 0.65 23.71 14.62 20.00
57 INT84894 Gene_expression of Calb2 45 0.73 24.65 7.81 20.00
58 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 20.00
59 INT93559 Gene_expression of Thbd 13 0.75 6.58 0.8 20.00
60 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 15.80
61 INT14690 Localization of CSF2 124 0.80 85.17 27.26 14.80
62 INT24231 Localization of SERPINB1 13 0.61 3.1 3.61 14.04
63 INT21604 Localization of BDNF-AS 12 0.73 9.5 0.79 14.04
64 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 10.68
65 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 7.84
66 INT310762 Negative_regulation of War 1 0.02 0.13 0.3 7.84
67 INT6021 Binding of PRL 18 0.48 12.55 4.3 7.80
68 INT12033 Binding of PLOD1 15 0.48 8.04 2.3 7.80
69 INT7033 Binding of FSHR 19 0.37 6.66 1.52 7.80
70 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
71 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
72 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
73 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
74 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
75 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
76 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
77 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
78 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
79 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
80 INT92517 Gene_expression of Grin1 105 0.78 29.53 39.43 5.00
81 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
82 INT47710 Negative_regulation of GRIN1 71 0.57 25.57 34.24 5.00
83 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
84 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
85 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
86 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
87 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
88 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
89 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
90 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
91 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 5.00
92 INT18513 Binding of GRIN1 32 0.47 9.44 15.08 5.00
93 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
94 INT18773 Localization of ALB 117 0.80 69.18 13.8 5.00
95 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
96 INT35801 Regulation of Alms1 34 0.38 20.88 12.38 5.00
97 INT69436 Negative_regulation of Gene_expression of ROS1 81 0.38 46.58 12.22 5.00
98 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
99 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 5.00
100 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
101 INT75907 Binding of LEP 53 0.46 46.65 8.44 5.00
102 INT69439 Regulation of ROS1 46 0.45 31.22 6.94 5.00
103 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88 5.00
104 INT20673 Binding of CDS1 18 0.31 1.96 5.72 5.00
105 INT135473 Negative_regulation of Gene_expression of Grin1 14 0.47 5.47 5.36 5.00
106 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 5.00
107 INT170604 Negative_regulation of Gene_expression of GOPC 50 0.35 12.71 4.51 5.00
108 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
109 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47 5.00
110 INT14086 Binding of SERPINB1 18 0.34 4.32 3.13 5.00
111 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 5.00
112 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
113 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 5.00
114 INT9466 Binding of APOB 27 0.41 19.36 1.56 5.00
115 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 5.00
116 INT216123 Negative_regulation of Cd68 2 0.41 1.96 1.48 5.00
117 INT152223 Binding of BEST1 10 0.29 6.67 1.46 5.00
118 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39 5.00
119 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 5.00
120 INT259692 Gene_expression of TNFAIP8L2 3 0.06 3.94 1.13 5.00
121 INT10303 Regulation of STH 16 0.60 16.14 0.95 5.00
122 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 5.00
123 INT200855 Positive_regulation of Kdr 14 0.45 11.14 0.77 5.00
124 INT200438 Negative_regulation of Gene_expression of SCN5A 6 0.36 1.93 0.71 5.00
125 INT80939 Positive_regulation of PDR 8 0.55 5.43 0.67 5.00
126 INT59792 Gene_expression of STH 14 0.75 15.2 0.61 5.00
127 INT162801 Localization of CALR 7 0.73 8.69 0.6 5.00
128 INT252612 Regulation of Gene_expression of SCN5A 5 0.35 0.56 0.53 5.00
129 INT259689 Gene_expression of KRT35 1 0.03 6.1 0.52 5.00
130 INT259690 Localization of TNFAIP8L2 2 0.06 1.94 0.51 5.00
131 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 5.00
132 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41 5.00
133 INT182465 Negative_regulation of Cd1d1 4 0.28 1.72 0.29 5.00
134 INT187017 Positive_regulation of Bcar1 2 0.44 2.02 0.27 5.00
135 INT75648 Negative_regulation of CTD 4 0.07 3.91 0.25 5.00
136 INT45510 Binding of Scn8a 4 0.31 3.89 0.25 5.00
137 INT216124 Negative_regulation of Pcna 3 0.13 2.06 0.19 5.00
138 INT259688 Positive_regulation of Localization of TNFAIP8L2 1 0.04 1.14 0.19 5.00
139 INT197104 Positive_regulation of Gene_expression of FLT4 1 0.56 3.45 0.19 5.00
140 INT197102 Localization of FLT4 4 0.65 2.89 0.17 5.00
141 INT246513 Regulation of IL4I1 2 0.10 2.06 0.15 5.00
142 INT197103 Binding of FLT4 2 0.29 3.08 0.14 5.00
143 INT23647 Negative_regulation of CDA 3 0.38 1.48 0.08 5.00
144 INT197101 Positive_regulation of Localization of FLT4 1 0.38 0.77 0.06 5.00
145 INT259693 Positive_regulation of Gene_expression of KRT35 1 0.03 1.22 0.04 5.00
146 INT182438 Localization of MPG 3 0.30 1.43 0.04 5.00
147 INT281251 Negative_regulation of LAMTOR1 1 0.12 1.42 0 5.00
148 INT248744 Negative_regulation of STH 2 0.41 1.02 0 5.00
149 INT259687 Binding of KRT35 1 0.02 0.55 0 5.00
150 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0 5.00
151 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0 5.00
152 INT281256 Positive_regulation of CCND2 1 0.20 1.42 0 5.00
153 INT281253 Negative_regulation of Negative_regulation of LAMTOR1 1 0.09 1.49 0 5.00
154 INT161203 Gene_expression of PCSK7 6 0.65 0.92 0 5.00
155 INT259691 Gene_expression of PRCD 1 0.02 1.13 0 5.00
156 INT66973 Gene_expression of Ua1 2 0.01 2.22 0 5.00
157 INT187016 Binding of Bcar1 1 0.31 1.36 0 5.00
158 INT252611 Protein_catabolism of AGRP 1 0.33 0.05 0 5.00
159 INT251628 Negative_regulation of CDKN2D 2 0.15 1.83 0 5.00
160 INT281250 Negative_regulation of Negative_regulation of CDKN2D 1 0.08 1.49 0 5.00
161 INT246512 Positive_regulation of IL4I1 2 0.26 1.05 0 5.00
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