D:Hydronephrosis

From wiki-pain
Jump to: navigation, search

pChart

Disease Term
Synonyms Hydronephroses
Documents 759
Hot Single Events 58
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hydronephrosis. They are ordered first by their relevance to Hydronephrosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 100.00
2 INT269838 Binding of Hsp90b1 and Tlr2 1 0.26 1.75 0.03 100.00
3 INT320492 KRT7 Positive_regulation of Pip 1 0.00 1.02 0.2 16.44
4 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 6.04
5 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
6 INT348637 Binding of TLE4 and OLFM1 1 0.01 1.67 0.24 5.00
7 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00
8 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14 5.00
9 INT88137 Ren Regulation of Gene_expression of Spp1 1 0.04 0.24 0.09 5.00
10 INT352579 CNTF Negative_regulation of Gene_expression of NPY 1 0.17 0.89 0.07 5.00
11 INT194244 Binding of SFSWAP and IgG 1 0.05 0.46 0 5.00
12 INT194226 Binding of IGHG3 and SFSWAP 1 0.03 0.93 0 5.00
13 INT349050 Binding of EPCAM and ZNF845 1 0.02 1.54 0 5.00
14 INT279145 Binding of VHL and RNF139 1 0.30 1.87 0 5.00
15 INT279143 Binding of TSN and RNF139 1 0.31 0.83 0 5.00
16 INT279144 RNF139 Regulation of TSN 1 0.24 3.47 0 5.00
17 INT194243 Binding of SFSWAP and Ighg1 1 0.01 0.46 0 5.00
18 INT192618 Atrx Regulation of Gene_expression of Hba-a1 1 0.08 0.45 0 5.00
19 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 5.00
20 INT349051 Binding of EPCAM and SCFV 1 0.03 1.37 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hydronephrosis. They are ordered first by their pain relevance and then by number of times they were reported in Hydronephrosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142594 Gene_expression of Tlr2 165 0.78 139.73 22.26 100.00
2 INT142593 Positive_regulation of Tlr2 85 0.70 75.9 13.62 100.00
3 INT152060 Gene_expression of VUR 75 0.67 83.83 2.34 100.00
4 INT142595 Negative_regulation of Tlr2 24 0.52 19.17 5.43 100.00
5 INT174688 Binding of Tlr2 45 0.42 36.65 5.25 100.00
6 INT265987 Protein_catabolism of ALAS2 1 0.01 2.77 0.07 100.00
7 INT221131 Localization of Tlr2 17 0.80 13.82 1.28 100.00
8 INT142596 Positive_regulation of Gene_expression of Tlr2 42 0.69 38.41 6.67 100.00
9 INT228188 Regulation of Gene_expression of Tlr2 5 0.45 6.96 0.71 100.00
10 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 99.96
11 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.96
12 INT269825 Negative_regulation of Transcription of Mmp9 2 0.27 1.61 0.36 99.84
13 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 99.84
14 INT256690 Binding of Hsp90b1 11 0.30 5.94 0.55 99.76
15 INT57070 Protein_catabolism of VUR 19 0.99 18.75 0.76 99.58
16 INT212758 Binding of Hmgb1 40 0.44 35.6 7.41 99.48
17 INT11918 Localization of CGB 35 0.51 8.21 15.01 99.48
18 INT39553 Gene_expression of Hmgb1 50 0.75 51.18 12.21 99.08
19 INT17817 Binding of VUR 41 0.48 46.85 0.95 99.06
20 INT105985 Transcription of Mmp9 11 0.66 8.55 3.02 98.48
21 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 98.44
22 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99 98.12
23 INT269822 Transcription of Timp2 1 0.36 1.43 0.36 98.12
24 INT269828 Transcription of Timp1 3 0.38 5.2 1.53 98.12
25 INT237382 Localization of VUR 11 0.72 14.58 0.11 98.08
26 INT4771 Gene_expression of CGB 23 0.67 14.22 3.42 97.88
27 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 96.76
28 INT114362 Localization of Hmgb1 127 0.78 120.28 23.26 96.48
29 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 96.48
30 INT88133 Positive_regulation of Spp1 8 0.66 10.07 1.33 96.12
31 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 95.80
32 INT85829 Gene_expression of CA9 14 0.68 12.59 1.4 95.80
33 INT85830 Positive_regulation of Gene_expression of CA9 4 0.41 5.47 1.02 95.80
34 INT160736 Negative_regulation of KRT7 9 0.41 10.08 0.68 95.76
35 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 95.60
36 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 95.40
37 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 95.36
38 INT85831 Positive_regulation of CA9 5 0.60 8.29 1.02 95.08
39 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 94.96
40 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 94.88
41 INT122813 Binding of Krt20 11 0.32 13.77 0.88 94.88
42 INT23146 Negative_regulation of Aprt 8 0.56 7.53 0.71 93.92
43 INT46530 Gene_expression of Pthlh 15 0.78 11.23 1.7 93.44
44 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 92.64
45 INT38379 Positive_regulation of VUR 15 0.58 15 0.71 92.04
46 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 91.96
47 INT4345 Gene_expression of Gtf3a 157 0.67 80.75 48.47 91.72
48 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 91.36
49 INT50446 Binding of MRGPRF 3 0.31 3.05 0.08 89.76
50 INT74446 Positive_regulation of Dync1h1 25 0.59 13 2.38 89.16
51 INT214 Localization of AVP 370 0.81 208.51 91.09 87.84
52 INT237383 Positive_regulation of Protein_catabolism of VUR 3 0.50 4.25 0.04 85.88
53 INT197367 Positive_regulation of Tbs1 5 0.07 2.44 0.8 84.96
54 INT204363 Gene_expression of VIS1 6 0.19 2.49 0.21 82.76
55 INT62386 Negative_regulation of Gene_expression of IGHG3 12 0.20 7.94 3.62 82.36
56 INT1127 Negative_regulation of IGHG3 32 0.28 21.1 7.37 82.36
57 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 82.04
58 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 81.64
59 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 79.48
60 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 78.88
61 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 78.84
62 INT39416 Gene_expression of Cd79a 81 0.64 45.17 6.08 78.84
63 INT105884 Binding of Bcl2 19 0.35 15.67 3 77.32
64 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 76.56
65 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88 76.32
66 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 75.88
67 INT83212 Positive_regulation of Gene_expression of Mki67 21 0.55 17.53 0.39 75.88
68 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 75.84
69 INT18773 Localization of ALB 117 0.80 69.18 13.8 75.84
70 INT109896 Negative_regulation of CA9 2 0.06 2.87 0.16 73.72
71 INT27935 Binding of Vim 21 0.36 15.65 2.61 73.04
72 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 72.92
73 INT36200 Gene_expression of S100A1 9 0.77 9.56 0.75 72.76
74 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 72.72
75 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 72.64
76 INT328097 Positive_regulation of MBOAT7 1 0.02 3.57 0.38 72.64
77 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91 72.28
78 INT269821 Regulation of Localization of Tlr2 1 0.27 1.04 0.07 71.80
79 INT27243 Positive_regulation of SPINK1 13 0.68 26.71 2.92 71.64
80 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72 71.44
81 INT212876 Negative_regulation of Gene_expression of Lipg 1 0.06 0.37 0.1 71.44
82 INT8801 Gene_expression of Csf3 71 0.74 45.6 10.83 71.28
83 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 71.12
84 INT193196 Regulation of MNX1 2 0.19 2.53 0.64 70.92
85 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17 70.88
86 INT16235 Positive_regulation of CGB 27 0.70 15.71 4.06 70.84
87 INT240748 Positive_regulation of Gene_expression of VUR 2 0.41 6.74 0.32 70.04
88 INT106381 Negative_regulation of CEACAM7 8 0.38 7.45 0.5 69.80
89 INT145502 Binding of dds 2 0.39 4.44 0.16 69.52
90 INT34007 Binding of Eno2 6 0.22 3.3 1.08 68.56
91 INT82374 Binding of SYP 13 0.36 13.69 0.85 68.56
92 INT214458 Binding of ALK 1 0.17 1.84 0.46 68.56
93 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 64.96
94 INT259690 Localization of TNFAIP8L2 2 0.06 1.94 0.51 61.56
95 INT259688 Positive_regulation of Localization of TNFAIP8L2 1 0.04 1.14 0.19 61.56
96 INT16616 Negative_regulation of SRD5A1 44 0.57 34.81 2.96 61.04
97 INT118217 Regulation of Cuzd1 2 0.30 2.36 0.91 59.12
98 INT112989 Gene_expression of AIP 3 0.56 25.4 4.23 59.04
99 INT9254 Negative_regulation of LDHA 23 0.43 13.3 2.2 58.24
100 INT56165 Negative_regulation of NSMCE1 1 0.20 0.92 0.05 57.92
101 INT2386 Gene_expression of Pgr 112 0.78 45.46 22.19 56.04
102 INT181756 Positive_regulation of Erbb2 6 0.46 4.12 0.28 54.56
103 INT165139 Positive_regulation of Krt7 3 0.10 1.85 0.09 54.56
104 INT4003 Positive_regulation of Gene_expression of IGHG3 31 0.46 20.38 3.16 53.80
105 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 53.80
106 INT233453 Gene_expression of Itm2b 8 0.74 8.45 0.99 51.92
107 INT183037 Gene_expression of MNX1 12 0.53 4.27 0.69 51.52
108 INT52021 Regulation of IGHG3 34 0.39 22.43 3.3 50.96
109 INT21999 Regulation of Gene_expression of IGHG3 8 0.30 3.26 1.84 50.96
110 INT287796 Regulation of Positive_regulation of IGHG3 1 0.02 1.19 0.03 50.96
111 INT117313 Negative_regulation of VUR 11 0.42 12.14 0.39 50.64
112 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 50.00
113 INT2140 Regulation of REN 104 0.62 28.24 24.49 50.00
114 INT182810 Gene_expression of Cuzd1 5 0.44 1.49 0.53 49.32
115 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 49.16
116 INT154732 Positive_regulation of Pip 7 0.41 5.93 0.6 49.16
117 INT105781 Positive_regulation of Krt7 4 0.04 3.34 0.3 49.16
118 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 46.64
119 INT22455 Binding of Nbr1 8 0.21 10.57 0.93 44.40
120 INT197368 Gene_expression of Tbs1 6 0.10 3.56 1 42.88
121 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 40.72
122 INT129454 Negative_regulation of Adamts13 6 0.30 7.78 0.31 38.64
123 INT195758 Negative_regulation of Transcription of Adamts13 1 0.03 2.23 0 38.64
124 INT195759 Transcription of Adamts13 1 0.05 2.22 0 38.24
125 INT111607 Gene_expression of CDH1 103 0.75 90.45 7.77 38.16
126 INT139237 Negative_regulation of Gene_expression of CDH1 23 0.57 24.31 1.28 38.16
127 INT279147 Negative_regulation of RNF139 1 0.53 5.41 0.06 37.36
128 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 37.04
129 INT22329 Gene_expression of Ptprc 36 0.66 15.84 1.59 37.04
130 INT101209 Gene_expression of Wt1 19 0.72 25.77 0.7 37.04
131 INT192619 Regulation of SMARCA2 1 0.06 0.3 0 31.44
132 INT192620 Regulation of BTAF1 1 0.06 0.3 0 31.44
133 INT68286 Regulation of SERPINB3 10 0.60 3.07 0.06 30.16
134 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 27.68
135 INT193195 Localization of MNX1 1 0.59 1.01 0.03 26.92
136 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 26.04
137 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 26.04
138 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 25.96
139 INT9188 Localization of HBG1 12 0.75 8.14 2.24 25.96
140 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 23.76
141 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 22.72
142 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 22.24
143 INT73731 Binding of RAPH1 9 0.33 14.58 0.5 22.08
144 INT192614 Gene_expression of Atrx 1 0.77 1.75 0 19.56
145 INT126374 Gene_expression of Gli3 6 0.77 3.67 2.02 18.76
146 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 18.56
147 INT2274 Regulation of Localization of INS 101 0.62 41.55 34.79 18.20
148 INT33008 Gene_expression of Dync1h1 41 0.68 23.85 3.82 18.20
149 INT2065 Binding of BTG3 15 0.36 10.9 4.65 18.08
150 INT114363 Positive_regulation of Hmgb1 50 0.67 48.92 8.15 16.88
151 INT256673 Positive_regulation of Hsp90b1 12 0.49 8.49 0.68 16.88
152 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 16.84
153 INT812 Localization of INS 1026 0.81 515.6 145.31 16.48
154 INT179524 Negative_regulation of Pip 7 0.38 4.49 0.29 15.24
155 INT75907 Binding of LEP 53 0.46 46.65 8.44 13.60
156 INT225029 Gene_expression of TRERF1 3 0.53 1.62 0.08 10.16
157 INT269823 Transcription of Hspd1 1 0.30 1.66 0.04 10.12
158 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 7.60
159 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 7.60
160 INT193198 Positive_regulation of Binding of DES 1 0.18 0.49 0 7.60
161 INT59784 Binding of DES 22 0.47 19.48 2.27 7.08
162 INT140245 Binding of Gli3 3 0.36 2.65 1.46 5.08
163 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
164 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
165 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
166 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
167 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
168 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
169 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
170 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
171 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
172 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
173 INT21737 Binding of MC1R 129 0.48 45.45 56.54 5.00
174 INT314 Positive_regulation of Ren 212 0.70 66.68 55.56 5.00
175 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
176 INT921 Regulation of GH1 172 0.60 52.88 51.04 5.00
177 INT2463 Localization of CCK 101 0.81 37.54 47.59 5.00
178 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81 5.00
179 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
180 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
181 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 5.00
182 INT16194 Binding of CNR1 82 0.48 20.75 39.59 5.00
183 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
184 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
185 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 5.00
186 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
187 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 5.00
188 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
189 INT1159 Negative_regulation of Agt 133 0.59 40.14 31.67 5.00
190 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
191 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 5.00
192 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 5.00
193 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
194 INT5055 Positive_regulation of IFNG 89 0.69 64.03 23.05 5.00
195 INT15458 Gene_expression of NPY 50 0.76 22.67 23.03 5.00
196 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
197 INT16794 Binding of App 103 0.48 64.87 19.79 5.00
198 INT65502 Regulation of App 77 0.62 52.05 19.44 5.00
199 INT18311 Positive_regulation of CD8A 145 0.69 113.48 19.44 5.00
200 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox